Much of the interest in amino acid metabolism has centered on the intermediary steps
involved in catabolism, the regulation of biosynthesis and transport, and genetic disorders
resulting in abnormal urinary and/or plasma concentrations of amino acids. This review will
focus on recent studies in which amino acid exchange between various organs has been
examined in a variety of physiologic and pathologic conditions in intact humans. Particular
emphasis, reflecting my own interest, will be focused on the relationship of amino acid …