Xenon and argon are the two noble gases used in tonne scale dark matter direct detection experiments. We compare the detection capability of both target elements for interactions due to a pseudoscalar mediator including loop-level contributions to the cross section. At tree-level this type of interaction depends on the nuclear spin and would thus not be detectable in argon-based detectors, since Ar has spin zero. However, at the loop-level the same interaction yields spin-independent contributions that would be detectable in an argon target and are not negligible with respect to the tree-level interactions in xenon, because these are momentum suppressed. In fact, the loop-level contributions are also important for xenon-based experiments at low recoil energies, which could change their discovery reach for this interaction.