User profiles for Mitzi I. Kuroda
 | Mitzi KurodaHarvard Medical School Verified email at genetics.med.harvard.edu Cited by 18110 |
Dynamic competition of polycomb and trithorax in transcriptional programming
Predicting regulatory potential from primary DNA sequences or transcription factor binding
patterns is not possible. However, the annotation of the genome by chromatin proteins, …
patterns is not possible. However, the annotation of the genome by chromatin proteins, …
Global regulation of X chromosomal genes by the MSL complex in Drosophila melanogaster
A long-standing model postulates that X-chromosome dosage compensation in Drosophila
occurs by twofold up-regulation of the single male X, but previous data cannot exclude an …
occurs by twofold up-regulation of the single male X, but previous data cannot exclude an …
Drosophila dosage compensation: a complex voyage to the X chromosome
ME Gelbart, MI Kuroda - 2009 - journals.biologists.com
Dosage compensation is the crucial process that equalizes gene expression from the X
chromosome between males (XY) and females (XX). In Drosophila, the male-specific lethal (MSL…
chromosome between males (XY) and females (XX). In Drosophila, the male-specific lethal (MSL…
A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome
The Drosophila MSL complex associates with active genes specifically on the male X chromosome
to acetylate histone H4 at lysine 16 and increase expression approximately 2-fold. To …
to acetylate histone H4 at lysine 16 and increase expression approximately 2-fold. To …
Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila
…, LM Lyman, R Richman, V Solovyev, MI Kuroda - Cell, 1995 - cell.com
Male-specific lethal-2 (msl-2) is a RING finger protein that is required for X chromosome
dosage compensation in Drosophila males. Consistent with the formation of a dosage …
dosage compensation in Drosophila males. Consistent with the formation of a dosage …
The maleless protein associates with the X chromosome to regulate dosage compensation in Drosophila
MI Kuroda, MJ Kernan, R Kreber, B Ganetzky… - Cell, 1991 - cell.com
The maleless (m/e) gene is one of four known regulatory loci required for increased transcription
(dosage compensation) of X-linked genes in D. melanogaster males. A predicted m/e …
(dosage compensation) of X-linked genes in D. melanogaster males. A predicted m/e …
Sex lethal controls dosage compensation in Drosophila by a non-splicing mechanism
Dosage compensation in Drosophila requires the male-specific lethal (msl) proteins (MSL)
to make gene expression from the single male X chromosome equivalent to that from both …
to make gene expression from the single male X chromosome equivalent to that from both …
[HTML][HTML] Epigenetic spreading of the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin
The multisubunit MSL dosage compensation complex binds to hundreds of sites along the
Drosophila single male X chromosome, mediating its hypertranscription. The male X …
Drosophila single male X chromosome, mediating its hypertranscription. The male X …
MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism
In Drosophila, X chromosome dosage compensation requires the male-specific lethal (MSL)
complex, which associates with actively transcribed genes on the single male X …
complex, which associates with actively transcribed genes on the single male X …
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
Two small RNAs regulate the timing of Caenorhabditis elegans development 1 , 2 . Transition
from the first to the second larval stage fates requires the 22-nucleotide lin-4 RNA 1 , 3 , 4 , …
from the first to the second larval stage fates requires the 22-nucleotide lin-4 RNA 1 , 3 , 4 , …