User profiles for Jinbo Huang

Jinbo Huang - Verified email at anu.edu.au - Cited by 1434
Huang, Jinbo - Verified email at bsse.ethz.ch - Cited by 1407

[PDF][PDF] The Effect of Restarts on the Efficiency of Clause Learning.

J Huang - IJCAI, 2007 - cdn.aaai.org
Given the common use of restarts in today’s clause learning SAT solvers, the task of choosing
a good restart policy appears to have attracted remarkably little interest. Many solvers, for …

Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

…, Z Guan, D Zhang, Z Liu, Z Gong, Q Wang, J Huang… - Nature, 2016 - nature.com
Chemical modifications of RNA have essential roles in a vast range of cellular processes 1 ,
2 , 3 . N 6 -methyladenosine (m 6 A) is an abundant internal modification in messenger RNA …

An electrogenetic interface to program mammalian gene expression by direct current

J Huang, S Xue, P Buchmann, AP Teixeira… - Nature …, 2023 - nature.com
Wearable electronic devices are playing a rapidly expanding role in the acquisition of
individuals’ health data for personalized medical interventions; however, wearables cannot yet …

Coordinated dispatch of electric power and district heating networks: A decentralized solution using optimality condition decomposition

J Huang, Z Li, QH Wu - Applied energy, 2017 - Elsevier
The strong linkage of electric power and heat supplies can be decoupled to reduce wind
power curtailment by exploiting the energy storage and regulation capabilities of the district …

Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase

J Huang, X Dong, Z Gong, LY Qin, S Yang… - Protein & …, 2019 - academic.oup.com
N 6 -methyladenosine (m 6 A), a ubiquitous RNA modification, is installed by METTL3-METTL14
complex. The structure of the heterodimeric complex between the methyltransferase …

Intrinsic impairment of CD4+CD25+ regulatory T cells in acquired aplastic anemia

…, S Lu, X Li, Y Shao, J Huang, Z Huang… - Blood, The Journal …, 2012 - ashpublications.org
Acquired aplastic anemia (AA) is an immune-mediated bone marrow (BM) failure attacked
by autoreactive effector T cells and BM is the main target organ. CD4 + CD25 + regulatory T …

Synthesis of phenanthridinones via palladium-catalyzed C (sp 2)–H aminocarbonylation of unprotected o-arylanilines

D Liang, Z Hu, J Peng, J Huang, Q Zhu - Chemical Communications, 2013 - pubs.rsc.org
An efficient synthesis of free (NH)-phenanthridinones through Pd-catalyzed C(sp2)–H
aminocarbonylation of unprotected o-arylanilines under an atmospheric pressure of CO has been …

Structure-based discovery of selective histone deacetylase 8 degraders with potent anticancer activity

J Huang, J Zhang, W Xu, Q Wu, R Zeng… - Journal of Medicinal …, 2022 - ACS Publications
Inducing protein degradation by proteolysis targeting chimeras has gained tremendous
momentum as a promising novel therapeutic strategy. Here, we report the design, synthesis, and …

Palladium-Catalyzed C(sp2)–H Cyanation Using Tertiary Amine Derived Isocyanide as a Cyano Source

J Peng, J Zhao, Z Hu, D Liang, J Huang, Q Zhu - Organic letters, 2012 - ACS Publications
An unprecedented palladium-catalyzed cyanation of aromatic C–H bonds by using tertiary
amine derived isocyanide as a novel cyano source was developed. Cu(TFA) 2 was used as a …

Arylative cyclization of 2-isocyanobiphenyls with anilines: one-pot synthesis of 6-arylphenanthridines via competitive reaction pathways

Z Xia, J Huang, Y He, J Zhao, J Lei, Q Zhu - Organic letters, 2014 - ACS Publications
A transition-metal-free method for the synthesis of C6 phenanthridine derivatives by arylative
cyclization of 2-isocyanobiphenyls with arylamines in one pot was developed. Mechanistic …