Two-photon absorption spectroscopy is an intensity dependent nonlinear effect related to
the excitation of virtual intermediate states. The classical two-photon absorption has an …

Chronic neurohormonal and mechanical stresses are central features of heart disease.
Increasing evidence supports a role for the transient receptor potential canonical channels …

The mechanistic target of rapamycin complex-1 (mTORC1) coordinates regulation of growth,
metabolism, protein synthesis and autophagy 1 . Its hyperactivation contributes to disease …

Rationale: Wound healing after myocardial infarction involves a highly regulated inflammatory
response that is initiated by the appearance of neutrophils to clear out dead cells and …

Cardiomyocytes undergo significant structural and functional changes after birth, and these
fundamental processes are essential for the heart to pump blood to the growing body. …

Rationale: The heart is exquisitely sensitive to mechanical stimuli to adapt rapidly to
physiological demands. In muscle lacking dystrophin, such as Duchenne muscular dystrophy, …

Results: Preventable deaths related to all management errors account for 39.6% of all trauma
deaths. Whereas, 25.7% of preventable deaths were related to management errors in the …

Rationale: One of the physiological mechanisms by which the heart adapts to a rise in blood
pressure is by augmenting myocyte stretch-mediated intracellular calcium, with a …

Thapsigargin (TG), by inducing perturbations in cellular Ca 2+ homeostasis, has been shown
to induce apoptosis. The molecular mechanisms of Ca 2+ perturbation-induced apoptosis …

Rationale: Stimulated PKG1α (protein kinase G-1α) phosphorylates TSC2 (tuberous
sclerosis complex 2) at serine 1365, potently suppressing mTORC1 (mechanistic [mammalian] …