Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Although the biochemical steps linking insulin resistance with the metabolic syndrome have
not been completely clarified, mounting experimental and clinical evidence indicate …

Non-alcoholic fatty liver disease (NAFLD) is a clinicopathologic entity increasingly
recognized as a major health burden in developed countries. It includes a spectrum of liver …

Previous studies have shown familial aggregation of insulin resistance and nonalcoholic
fatty liver disease (NAFLD). Therefore, we aimed to examine whether family history of …

BACKGROUND/AIMS: The importance of epigenetic changes in etiology and pathogenesis
of disease has been increasingly recognized. However, the role of epigenetic alterations in …

High-calorie food leads to nonalcoholic fatty liver disease (NAFLD) through dysregulation of
genes involved in lipid metabolism, but the precise mechanism remains unclear. DNA …

OBJECTIVES: Mitochondria play a major role in cell energy-generating processes and
integrate several signalling pathways to control cellular life and death. DESIGN AND …

Nonalcoholic steatohepatitis (NASH) is common in morbidly obese persons. Liver biopsy is
diagnostic but technically challenging in such individuals. This study was undertaken to …

The epidemic occurrence of obesity has led to a rapid increase in the incidence of non-
alcoholic fatty liver disease (NAFLD) in industrial countries. The disease spectrum includes …

Abstract The adiponutrin (PNPLA3) rs738409 polymorphism has been found to be
associated with susceptibility to non-alcoholic fatty liver disease (NAFLD) in various cohorts …