p62, upregulated during preneoplasia, induces hepatocellular carcinogenesis by maintaining survival of stressed HCC-initiating cells A Umemura, F He, K Taniguchi, H Nakagawa, S Yamachika, ... Cancer cell 29 (6), 935-948, 2016 | 439 | 2016 |
CD8+ T cell metabolism in infection and cancer M Reina-Campos, NE Scharping, AW Goldrath Nature Reviews Immunology 21 (11), 718-738, 2021 | 321 | 2021 |
Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis T Valencia, JY Kim, S Abu-Baker, J Moscat-Pardos, CS Ahn, ... Cancer cell 26 (1), 121-135, 2014 | 318 | 2014 |
Metabolism shapes the tumor microenvironment M Reina-Campos, J Moscat, M Diaz-Meco Current opinion in cell biology 48, 47-53, 2017 | 274 | 2017 |
p62/SQSTM1 by binding to vitamin D receptor inhibits hepatic stellate cell activity, fibrosis, and liver cancer A Duran, ED Hernandez, M Reina-Campos, EA Castilla, S Subramaniam, ... Cancer cell 30 (4), 595-609, 2016 | 240 | 2016 |
Increased serine and one-carbon pathway metabolism by PKCλ/ι deficiency promotes neuroendocrine prostate cancer M Reina-Campos, JF Linares, A Duran, T Cordes, A L'Hermitte, MG Badur, ... Cancer Cell 35 (3), 385-400. e9, 2019 | 172 | 2019 |
Amino acid activation of mTORC1 by a PB1-domain-driven kinase complex cascade JF Linares, A Duran, M Reina-Campos, P Aza-Blanc, A Campos, J Moscat, ... Cell reports 12 (8), 1339-1352, 2015 | 122 | 2015 |
Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population JJ Milner, H Nguyen, K Omilusik, M Reina-Campos, M Tsai, C Toma, ... Proceedings of the National Academy of Sciences 117 (41), 25667-25678, 2020 | 104 | 2020 |
Adipocyte p62/SQSTM1 suppresses tumorigenesis through opposite regulations of metabolism in adipose tissue and tumor J Huang, A Duran, M Reina-Campos, T Valencia, EA Castilla, TD Müller, ... Cancer cell 33 (4), 770-784. e6, 2018 | 101 | 2018 |
ATF4-induced metabolic reprograming is a synthetic vulnerability of the p62-deficient tumor stroma JF Linares, T Cordes, A Duran, M Reina-Campos, T Valencia, CS Ahn, ... Cell metabolism 26 (6), 817-829. e6, 2017 | 101 | 2017 |
NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly F He, L Antonucci, S Yamachika, Z Zhang, K Taniguchi, A Umemura, ... Journal of hepatology 72 (6), 1182-1195, 2020 | 95 | 2020 |
The complexity of the serine glycine one-carbon pathway in cancer M Reina-Campos, MT Diaz-Meco, J Moscat Journal of Cell Biology 219 (1), e201907022, 2019 | 90 | 2019 |
Repression of intestinal stem cell function and tumorigenesis through direct phosphorylation of β-catenin and Yap by PKCζ V Llado, Y Nakanishi, A Duran, M Reina-Campos, PM Shelton, JF Linares, ... Cell reports 10 (5), 740-754, 2015 | 88 | 2015 |
Stromal SOX2 upregulation promotes tumorigenesis through the generation of a SFRP1/2-expressing cancer-associated fibroblast population H Kasashima, A Duran, A Martinez-Ordoñez, Y Nakanishi, H Kinoshita, ... Developmental cell 56 (1), 95-110. e10, 2021 | 76 | 2021 |
The dual roles of the atypical protein kinase Cs in cancer M Reina-Campos, MT Diaz-Meco, J Moscat Cancer cell 36 (3), 218-235, 2019 | 76 | 2019 |
Control of Paneth cell fate, intestinal inflammation, and tumorigenesis by PKCλ/ι Y Nakanishi, M Reina-Campos, N Nakanishi, V Llado, L Elmen, ... Cell reports 16 (12), 3297-3310, 2016 | 68 | 2016 |
The secretion of miR-200s by a PKCζ/ADAR2 signaling axis promotes liver metastasis in colorectal cancer PM Shelton, A Duran, Y Nakanishi, M Reina-Campos, H Kasashima, ... Cell reports 23 (4), 1178-1191, 2018 | 63 | 2018 |
Simultaneous loss of both atypical protein kinase C genes in the intestinal epithelium drives serrated intestinal cancer by impairing immunosurveillance Y Nakanishi, A Duran, A L’Hermitte, PM Shelton, N Nakanishi, ... Immunity 49 (6), 1132-1147. e7, 2018 | 46 | 2018 |
Metabolic reprogramming of the tumor microenvironment by p62 and its partners M Reina-Campos, PM Shelton, MT Diaz-Meco, J Moscat Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1870 (1), 88-95, 2018 | 44 | 2018 |
Metabolic programs of T cell tissue residency empower tumour immunity M Reina-Campos, M Heeg, K Kennewick, IT Mathews, G Galletti, V Luna, ... Nature 621 (7977), 179-187, 2023 | 39 | 2023 |