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Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome. bioRxiv. 2024 Oct 22.
Wang HB, Smale NE, Brown SH, Villanueva SAM, Zhou D, Mulji A, Nguyen-Ngo K, Harvey JR, Ghiani CA, Colwell CS. PMID: 39345407; PMCID: PMC11429936.
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Circadian Interventions in Preclinical Models of Huntington's Disease: A Narrative Review. Biomedicines. 2024 Aug 06; 12(8).
Dell'Angelica D, Singh K, Colwell CS, Ghiani CA. PMID: 39200241; PMCID: PMC11351982.
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PubMed Mentions:
1
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Scheduled feeding improves sleep in a mouse model of Huntington's disease. Front Neurosci. 2024; 18:1427125.
Chiem E, Zhao K, Dell'Angelica D, Ghiani CA, Paul KN, Colwell CS. PMID: 39161652; PMCID: PMC11330895.
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PubMed Mentions:
1
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Relative importance of intensity and spectrum of artificial light at night in disrupting behavior of a nocturnal rodent. J Exp Biol. 2024 Jul 15; 227(14).
Longcore T, Villanueva SAMB, Nguyen-Ngo K, Ghiani CA, Harrison B, Colwell CS. PMID: 38873751; PMCID: PMC11418196.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Scheduled feeding improves sleep in a mouse model of Huntington's disease. bioRxiv. 2024 May 07.
Chiem E, Zhao K, Dell'Angelica D, Ghiani CA, Paul KN, Colwell CS. PMID: 38766112; PMCID: PMC11100594.
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Sex differences in sleep architecture in a mouse model of Huntington's disease. J Neurosci Res. 2024 01; 102(1):e25290.
Chiem E, Zhao K, Stark G, Ghiani CA, Colwell CS, Paul KN. PMID: 38284849.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Hydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice. Sleep Adv. 2024; 5(1):zpad057.
Vincent SM, Madani M, Dikeman D, Golden K, Crocker N, Jackson C, Wimmer SP, Dover M, Tucker A, Ghiani CA, Colwell CS, LeBaron TW, Tarnava A, Paul KN. PMID: 38264142; PMCID: PMC10803172.
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PubMed Mentions:
1
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Sex Differences in Sleep Phenotypes in the BACHD Mouse Model of Huntington's Disease. bioRxiv. 2023 Apr 28.
Chiem E, Zhao K, Stark G, Ghiani CA, Colwell CS, Paul KN. PMID: 37162913; PMCID: PMC10168394.
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Long wavelength light reduces the negative consequences of dim light at night. Neurobiol Dis. 2023 01; 176:105944.
Wang HB, Zhou D, Luk SHC, In Cha H, Mac A, Chae R, Matynia A, Harrison B, Afshari S, Block GD, Ghiani CA, Colwell CS. PMID: 36493974; PMCID: PMC10594349.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Dietary ketosis improves circadian dysfunction as well as motor symptoms in the BACHD mouse model of Huntington's disease. Front Nutr. 2022; 9:1034743.
Whittaker DS, Tamai TK, Bains RS, Villanueva SAM, Luk SHC, Dell'Angelica D, Block GD, Ghiani CA, Colwell CS. PMID: 36407529; PMCID: PMC9669764.
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PubMed Mentions:
7
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Targeted Genetic Reduction of Mutant Huntingtin Lessens Cardiac Pathology in the BACHD Mouse Model of Huntington's Disease. Front Cardiovasc Med. 2021; 8:810810.
Park S, Luk SHC, Bains RS, Whittaker DS, Chiem E, Jordan MC, Roos KP, Ghiani CA, Colwell CS. PMID: 35004919; PMCID: PMC8739867.
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PubMed Mentions:
6
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Melatonin treatment of repetitive behavioral deficits in the Cntnap2 mouse model of autism spectrum disorder. Neurobiol Dis. 2020 11; 145:105064.
Wang HB, Tahara Y, Luk SHC, Kim YS, Hitchcock ON, MacDowell Kaswan ZA, In Kim Y, Block GD, Ghiani CA, Loh DH, Colwell CS. PMID: 32889171; PMCID: PMC7597927.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Sex-dimorphic effects of biogenesis of lysosome-related organelles complex-1 deficiency on mouse perinatal brain development. J Neurosci Res. 2021 01; 99(1):67-89.
Lee FY, Larimore J, Faundez V, Dell'Angelica EC, Ghiani CA. PMID: 32436302; PMCID: PMC7677168.
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PubMed Mentions: Fields:
Translation:
Animals
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Circadian dysfunction in the Q175 model of Huntington's disease: Network analysis. J Neurosci Res. 2019 12; 97(12):1606-1623.
Smarr B, Cutler T, Loh DH, Kudo T, Kuljis D, Kriegsfeld L, Ghiani CA, Colwell CS. PMID: 31359503; PMCID: PMC7105276.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Quantitative assessments reveal improved neuroscience engagement and learning through outreach. J Neurosci Res. 2019 09; 97(9):1153-1162.
Saravanapandian V, Sparck EM, Cheng KY, Yu F, Yaeger C, Hu T, Suthana N, Romero-Calderón R, Ghiani CA, Evans CJ, Carpenter EM, Ge W. PMID: 30985023.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Potential Circadian Rhythms in Oligodendrocytes? Working Together Through Time. Neurochem Res. 2020 Mar; 45(3):591-605.
Colwell CS, Ghiani CA. PMID: 30906970; PMCID: PMC6761052.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Sleep/Wake Disruption in a Mouse Model of BLOC-1 Deficiency. Front Neurosci. 2018; 12:759.
Lee FY, Wang HB, Hitchcock ON, Loh DH, Whittaker DS, Kim YS, Aiken A, Kokikian C, Dell'Angelica EC, Colwell CS, Ghiani CA. PMID: 30498428; PMCID: PMC6249416.
View in:
PubMed Mentions:
11
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Pathophysiology in the suprachiasmatic nucleus in mouse models of Huntington's disease. J Neurosci Res. 2018 12; 96(12):1862-1875.
Kuljis D, Kudo T, Tahara Y, Ghiani CA, Colwell CS. PMID: 30168855; PMCID: PMC7105277.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Circadian-based Treatment Strategy Effective in the BACHD Mouse Model of Huntington's Disease. J Biol Rhythms. 2018 10; 33(5):535-554.
Whittaker DS, Loh DH, Wang HB, Tahara Y, Kuljis D, Cutler T, Ghiani CA, Shibata S, Block GD, Colwell CS. PMID: 30084274.
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PubMed Mentions:
28 Fields:
Translation:
Animals
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BLOC-1 deficiency causes alterations in amino acid profile and in phospholipid and adenosine metabolism in the postnatal mouse hippocampus. Sci Rep. 2017 07 12; 7(1):5231.
van Liempd SM, Cabrera D, Lee FY, González E, Dell'Angelica EC, Ghiani CA, Falcon-Perez JM. PMID: 28701731; PMCID: PMC5507893.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Neurocardiovascular deficits in the Q175 mouse model of Huntington's disease. Physiol Rep. 2017 Jun; 5(11).
Cutler TS, Park S, Loh DH, Jordan MC, Yokota T, Roos KP, Ghiani CA, Colwell CS. PMID: 28576852; PMCID: PMC5471434.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Cellular and molecular mechanisms of neurodevelopmental disorders. J Neurosci Res. 2017 05; 95(5):1093-1096.
Ghiani CA, Faundez V. PMID: 28225560; PMCID: PMC5352532.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Blue light therapy improves circadian dysfunction as well as motor symptoms in two mouse models of Huntington's disease. Neurobiol Sleep Circadian Rhythms. 2017 Jan; 2:39-52.
Wang HB, Whittaker DS, Truong D, Mulji AK, Ghiani CA, Loh DH, Colwell CS. PMID: 31236494; PMCID: PMC6575206.
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PubMed Mentions:
24
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Sex Differences in Circadian Dysfunction in the BACHD Mouse Model of Huntington's Disease. PLoS One. 2016; 11(2):e0147583.
Kuljis DA, Gad L, Loh DH, MacDowell Kaswan Z, Hitchcock ON, Ghiani CA, Colwell CS. PMID: 26871695; PMCID: PMC4752447.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease. PLoS One. 2016; 11(1):e0147269.
Schroeder AM, Wang HB, Park S, Jordan MC, Gao F, Coppola G, Fishbein MC, Roos KP, Ghiani CA, Colwell CS. PMID: 26807590; PMCID: PMC4725962.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Misaligned feeding impairs memories. Elife. 2015 Dec 10; 4.
Loh DH, Jami SA, Flores RE, Truong D, Ghiani CA, O'Dell TJ, Colwell CS. PMID: 26652002; PMCID: PMC4729691.
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PubMed Mentions:
32 Fields:
Translation:
Animals
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Circadian rhythm disruption in a mouse model of Rett syndrome circadian disruption in RTT. Neurobiol Dis. 2015 May; 77:155-64.
Li Q, Loh DH, Kudo T, Truong D, Derakhshesh M, Kaswan ZM, Ghiani CA, Tsoa R, Cheng Y, Sun YE, Colwell CS. PMID: 25779967.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Reductions in synaptic proteins and selective alteration of prepulse inhibition in male C57BL/6 mice after postnatal administration of a VIP receptor (VIPR2) agonist. Psychopharmacology (Berl). 2015 Jun; 232(12):2181-9.
Ago Y, Condro MC, Tan YV, Ghiani CA, Colwell CS, Cushman JD, Fanselow MS, Hashimoto H, Waschek JA. PMID: 25575489; PMCID: PMC4433594.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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STAT3-mediated astrogliosis protects myelin development in neonatal brain injury. Ann Neurol. 2012 Nov; 72(5):750-65.
Nobuta H, Ghiani CA, Paez PM, Spreuer V, Dong H, Korsak RA, Manukyan A, Li J, Vinters HV, Huang EJ, Rowitch DH, Sofroniew MV, Campagnoni AT, de Vellis J, Waschek JA. PMID: 22941903; PMCID: PMC3514566.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Project brainstorm: using neuroscience to connect college students with local schools. PLoS Biol. 2012; 10(4):e1001310.
Romero-Calderón R, O'Hare ED, Suthana NA, Scott-Van Zeeland AA, Rizk-Jackson A, Attar A, Madsen SK, Ghiani CA, Evans CJ, Watson JB. PMID: 22529746; PMCID: PMC3328426.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Golli myelin basic proteins stimulate oligodendrocyte progenitor cell proliferation and differentiation in remyelinating adult mouse brain. Glia. 2012 Jul; 60(7):1078-93.
Paez PM, Cheli VT, Ghiani CA, Spreuer V, Handley VW, Campagnoni AT. PMID: 22447683.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Decreased reelin expression and organophosphate pesticide exposure alters mouse behaviour and brain morphology. ASN Neuro. 2012 Feb 18; 5(1):e00106.
Mullen BR, Khialeeva E, Hoffman DB, Ghiani CA, Carpenter EM. PMID: 23298182; PMCID: PMC3575035.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Early effects of lipopolysaccharide-induced inflammation on foetal brain development in rat. ASN Neuro. 2011 Nov 17; 3(4).
Ghiani CA, Mattan NS, Nobuta H, Malvar JS, Boles J, Ross MG, Waschek JA, Carpenter EM, Fisher RS, de Vellis J. PMID: 22007738; PMCID: PMC3218569.
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PubMed Mentions:
23 Fields:
Translation:
Animals
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Dysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade. ASN Neuro. 2011 May 27; 3(2).
Ghiani CA, Dell'Angelica EC. PMID: 21504412; PMCID: PMC3155195.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Aspartoacylase deficiency affects early postnatal development of oligodendrocytes and myelination. Neurobiol Dis. 2010 Nov; 40(2):432-43.
Mattan NS, Ghiani CA, Lloyd M, Matalon R, Bok D, Casaccia P, de Vellis J. PMID: 20637282; PMCID: PMC2964840.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Voluntary exercise increases oligodendrogenesis in spinal cord. Int J Neurosci. 2010 Apr; 120(4):280-90.
Krityakiarana W, Espinosa-Jeffrey A, Ghiani CA, Zhao PM, Topaldjikian N, Gomez-Pinilla F, Yamaguchi M, Kotchabhakdi N, de Vellis J. PMID: 20374076; PMCID: PMC2852894.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth. Mol Psychiatry. 2010 Feb; 15(2):115, 204-15.
Ghiani CA, Starcevic M, Rodriguez-Fernandez IA, Nazarian R, Cheli VT, Chan LN, Malvar JS, de Vellis J, Sabatti C, Dell'Angelica EC. PMID: 19546860; PMCID: PMC2811213.
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PubMed Mentions:
85 Fields:
Translation:
AnimalsCells
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Inhibition of p53 transcriptional activity: a potential target for future development of therapeutic strategies for primary demyelination. J Neurosci. 2008 Jun 11; 28(24):6118-27.
Li J, Ghiani CA, Kim JY, Liu A, Sandoval J, DeVellis J, Casaccia-Bonnefil P. PMID: 18550754; PMCID: PMC2962898.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Exercise decreases myelin-associated glycoprotein expression in the spinal cord and positively modulates neuronal growth. Glia. 2007 Jul; 55(9):966-75.
Ghiani CA, Ying Z, de Vellis J, Gomez-Pinilla F. PMID: 17497667; PMCID: PMC2805662.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Genetic program of neuronal differentiation and growth induced by specific activation of NMDA receptors. Neurochem Res. 2007 Feb; 32(2):363-76.
Ghiani CA, Beltran-Parrazal L, Sforza DM, Malvar JS, Seksenyan A, Cole R, Smith DJ, Charles A, Ferchmin PA, de Vellis J. PMID: 17191130.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Growth factor-dependent actions of PACAP on oligodendrocyte progenitor proliferation. Regul Pept. 2006 Nov 15; 137(1-2):58-66.
Lelievre V, Ghiani CA, Seksenyan A, Gressens P, de Vellis J, Waschek JA. PMID: 16989910.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Gene expression is differentially regulated by neurotransmitters in embryonic neuronal cortical culture. J Neurochem. 2006 Apr; 97 Suppl 1:35-43.
Ghiani CA, Lelievre V, Beltran-Parrazal L, Sforza DM, Malvar J, Smith DJ, Charles AC, Ferchmin PA, de Vellis J. PMID: 16635248.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Regulation of Kv1 subunit expression in oligodendrocyte progenitor cells and their role in G1/S phase progression of the cell cycle. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):2350-5.
Chittajallu R, Chen Y, Wang H, Yuan X, Ghiani CA, Heckman T, McBain CJ, Gallo V. PMID: 11854528; PMCID: PMC122368.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Inhibition of cyclin E-cyclin-dependent kinase 2 complex formation and activity is associated with cell cycle arrest and withdrawal in oligodendrocyte progenitor cells. J Neurosci. 2001 Feb 15; 21(4):1274-82.
Ghiani C, Gallo V. PMID: 11160398; PMCID: PMC6762244.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Glutamate receptors in glia: new cells, new inputs and new functions. Trends Pharmacol Sci. 2000 Jul; 21(7):252-8.
Gallo V, Ghiani CA. PMID: 10871893.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Glial heterogeneity in expression of the inwardly rectifying K(+) channel, Kir4.1, in adult rat CNS. Glia. 2000 Jun; 30(4):362-72.
Poopalasundaram S, Knott C, Shamotienko OG, Foran PG, Dolly JO, Ghiani CA, Gallo V, Wilkin GP. PMID: 10797616.
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PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
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Voltage-activated K+ channels and membrane depolarization regulate accumulation of the cyclin-dependent kinase inhibitors p27(Kip1) and p21(CIP1) in glial progenitor cells. J Neurosci. 1999 Jul 01; 19(13):5380-92.
Ghiani CA, Yuan X, Eisen AM, Knutson PL, DePinho RA, McBain CJ, Gallo V. PMID: 10377348; PMCID: PMC6782320.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Neurotransmitter receptor activation triggers p27(Kip1 )and p21(CIP1) accumulation and G1 cell cycle arrest in oligodendrocyte progenitors. Development. 1999 Feb; 126(5):1077-90.
Ghiani CA, Eisen AM, Yuan X, DePinho RA, McBain CJ, Gallo V. PMID: 9927607.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Antagonism by abecarnil of enhanced acetylcholine release in the rat brain during anticipation but not consumption of food. Pharmacol Biochem Behav. 1998 Mar; 59(3):657-62.
Ghiani CA, Dazzi L, Maciocco E, Flore G, Maira G, Biggio G. PMID: 9512068.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam. Neurochem Res. 1997 Jun; 22(6):693-7.
Serra M, Cuccu R, Ghiani CA, Pisu MG, Murgia A, Biggio G. PMID: 9178952.
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Translation:
AnimalsCells
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K+ channel expression and cell proliferation are regulated by intracellular sodium and membrane depolarization in oligodendrocyte progenitor cells. J Neurosci. 1997 Apr 15; 17(8):2669-82.
Knutson P, Ghiani CA, Zhou JM, Gallo V, McBain CJ. PMID: 9092588; PMCID: PMC6573116.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolo[2,1-b]-benzothiazol-, -thiazol- or -oxazol-1-ones in rodents. J Pharm Pharmacol. 1996 Aug; 48(8):834-40.
Trapani G, Franco M, Latrofa A, Carotti A, Cellamare S, Serra M, Ghiani CA, Tuligi G, Biggio G, Liso G. PMID: 8887735.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain. Biochem Pharmacol. 1996 Jun 14; 51(11):1527-34.
Ghiani CA, Tuligi G, Maciocco E, Serra M, Sanna E, Biggio G. PMID: 8630094.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Failure of chronic treatment with abecarnil to induce contigent and noncontingent tolerance in pentylenetetrazol-kindled rats. Epilepsia. 1996 Apr; 37(4):332-5.
Serra M, Ghiani CA, Maciocco E, Pisu MG, Tuligi G, Porceddu ML, Giggio G. PMID: 8603637.
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PubMed Mentions: Fields:
Translation:
Animals
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Antagonism of isoniazid-induced convulsions by abecarnil in mice tolerant to diazepam. Pharmacol Biochem Behav. 1995 Oct; 52(2):249-54.
Serra M, Ghiani CA, Motzo C, Porceddu ML, Biggio G. PMID: 8577786.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Felbamate antagonizes isoniazid- and FG 7142-induced reduction of GABAA receptor function in mouse brain. Eur J Pharmacol. 1994 Nov 24; 265(3):185-8.
Serra M, Ghiani CA, Spano S, Biggio G. PMID: 7875235.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Long-term treatment with abecarnil fails to induce tolerance in mice. Eur J Pharmacol. 1994 Jun 23; 259(1):1-6.
Serra M, Ghiani CA, Motzo C, Porceddu ML, Biggio G. PMID: 7957586.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor function. J Pharmacol Exp Ther. 1994 Apr; 269(1):32-8.
Serra M, Ghiani CA, Motzo C, Cuccheddu T, Floris S, Giusti P, Biggio G. PMID: 8169838.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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NMDA receptor function is enhanced in the hippocampus of aged rats. Neurochem Res. 1994 Apr; 19(4):483-7.
Serra M, Ghiani CA, Foddi MC, Motzo C, Biggio G. PMID: 7915012.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Chronic administration of an anticonvulsant dose of imidazenil fails to induce tolerance of GABAA receptor function in mice. Eur J Pharmacol. 1994 Mar 21; 254(3):299-302.
Ghiani CA, Serra M, Motzo C, Giusti P, Cuccheddu T, Porceddu ML, Biggio G. PMID: 8013567.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Failure of flumazenil to precipitate a withdrawal syndrome in cats chronically treated with the new anxioselective beta-carboline derivative abecarnil. Behav Pharmacol. 1993 Oct; 4(5):529-533.
Serra M, Ghiani CA, Foddi MC, Galici R, Motzo C, Biggio G. PMID: 11224221.
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PubMed Mentions:
2 Fields:
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Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors. Psychopharmacol Ser. 1993; 11:62-78.
Serra M, Ghiani CA, Motzo C, Biggio G. PMID: 7908434.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Pharmacology of gamma-aminobutyric acidA receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta-carboline derivative abecarnil. J Pharmacol Exp Ther. 1992 Dec; 263(3):1360-8.
Serra M, Foddi MC, Ghiani CA, Melis MA, Motzo C, Concas A, Sanna E, Biggio G. PMID: 1361574.
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PubMed Mentions:
5 Fields:
Translation:
Animals