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[Takayasu arteritis]

Rev Med Interne. 2016 Apr;37(4):223-9. doi: 10.1016/j.revmed.2015.12.024. Epub 2016 Jan 27.
[Article in French]

Abstract

Takayasu arteritis is a chronic inflammatory vasculitis of unknown origin affecting large vessels, predominantly the aorta and its main branches. Vessel inflammation leads to wall thickening, fibrosis, and stenosis. The lesions are often asymptomatic leading to limb numbness, transient ischemic attack, cardiovascular event and renovascular hypertension. Treatment is based on corticosteroids, immunosuppressant and biologics if necessary. Endovascular treatment and open-surgery can be useful for end-organ ischemia relief.

Keywords: Aortite; Aortitis; Maladie de Takayasu; Takayasu arteritis.

Publication types

  • Review

MeSH terms

  • Aorta / pathology
  • Aortitis / diagnosis
  • Aortitis / etiology
  • Aortitis / therapy
  • Constriction, Pathologic / diagnosis
  • Constriction, Pathologic / etiology
  • Disease Progression
  • Female
  • Humans
  • Hypertension, Renovascular / diagnosis
  • Hypertension, Renovascular / etiology
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / therapy
  • Takayasu Arteritis* / diagnosis
  • Takayasu Arteritis* / epidemiology
  • Takayasu Arteritis* / etiology
  • Takayasu Arteritis* / pathology
  • Takayasu Arteritis* / therapy