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Treatment of obesity: Pharmacotherapy trends in the United States from 1999 to 2010

Obesity (Silver Spring). 2015 Aug;23(8):1721-8. doi: 10.1002/oby.21136.

Abstract

Objective: To describe the antiobesity drug-prescribing patterns of US physicians over the past decade.

Methods: Data for adult patients were obtained from the National Ambulatory Medical Care Survey and the National Hospital Ambulatory Medical Care Survey. Obesity was identified using ICD-9 codes, BMI values, and a chronic-obesity-condition variable. For patients with obesity, a logistic-regression model was estimated to determine the odds of receiving pharmacotherapy.

Results: Of the 987 million visits by patients with obesity from 2005 to 2010, 2.0% mentioned an antiobesity drug. Additionally, there were 6.5 million visits by patients without obesity but with an antiobesity drug mention. Visits made by females (OR = 2.89; 95% CI: 2.08-4.03), by white patients (OR = 1.55; 95% CI: 1.08-2.24), by younger adults (OR = 1.71; 95% CI: 1.34-2.20), and in the South (OR = 3.39; 95% CI: 1.49-7.72) were more likely to involve an antiobesity drug prescription.

Conclusions: Only 1 in 50 patients with obesity received a prescription for an antiobesity medication. Moreover, in contrast to what the 1998 Guidelines suggested, physicians tended to prescribe antiobesity medications to self-paying, young, white females, many of whom lived in the South, and not all of whom had obesity.

Publication types

  • Historical Article

MeSH terms

  • Adult
  • Aged
  • Anti-Obesity Agents / therapeutic use*
  • Drug Therapy / methods*
  • Female
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Male
  • Middle Aged
  • Obesity / drug therapy*
  • Obesity / mortality
  • Obesity / therapy*
  • United States
  • Young Adult

Substances

  • Anti-Obesity Agents