Expression of proliferating cell nuclear antigen and bcl-2 during a pseudomenopausal state induced by presurgical treatment of uterine leiomyomas with gonadotropin-releasing hormone analogues plus tibolone

Int J Gynecol Pathol. 2005 Jul;24(3):286-91. doi: 10.1097/01.pgp.0000163848.29506.67.

Authors

Marianna De Falco¹, Stefania Staibano, Fabrizio Pollio, Gaetano Salvatore, Massimo Pontillo, Francesca Ciociola, Gelsomina Mansueto, Andrea Di Lieto

Affiliation

¹ Department of Obstetrical-Gynaecological and Urological Science and Reproductive Medicine, University Federico II of Naples, Napoli, Italy.

PMID: 15968206
DOI: 10.1097/01.pgp.0000163848.29506.67

No abstract available

Publication types

Clinical Trial
Randomized Controlled Trial

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Combined Modality Therapy
Female
Humans
Immunohistochemistry
Leiomyoma / drug therapy*
Leiomyoma / metabolism
Leiomyoma / surgery
Leuprolide / therapeutic use*
Norpregnenes / therapeutic use*
Proliferating Cell Nuclear Antigen / biosynthesis*
Proto-Oncogene Proteins c-bcl-2 / biosynthesis*
Uterine Neoplasms / drug therapy*
Uterine Neoplasms / metabolism
Uterine Neoplasms / surgery

Substances

Norpregnenes
Proliferating Cell Nuclear Antigen
Proto-Oncogene Proteins c-bcl-2
Leuprolide
tibolone