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Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis.
Xiang X, Bhowmick K, Shetty K, Ohshiro K, Yang X, Wong LL, Yu H, Latham PS, Satapathy SK, Brennan C, Dima RJ, Chambwe N, Sharifova G, Cacaj F, John S, Crawford JM, Huang H, Dasarathy S, Krainer AR, He AR, Amdur RL, Mishra L. Xiang X, et al. Among authors: yang x. Genes Cancer. 2024 Feb 1;15:1-14. doi: 10.18632/genesandcancer.234. eCollection 2024. Genes Cancer. 2024. PMID: 38323119 Free PMC article.
Mice with dysfunctional TGF-β signaling develop altered intestinal microbiome and colorectal cancer resistant to 5FU.
Wang Z, Hopson LM, Singleton SS, Yang X, Jogunoori W, Mazumder R, Obias V, Lin P, Nguyen BN, Yao M, Miller L, White J, Rao S, Mishra L. Wang Z, et al. Among authors: yang x. Biochim Biophys Acta Mol Basis Dis. 2021 Oct 1;1867(10):166179. doi: 10.1016/j.bbadis.2021.166179. Epub 2021 May 31. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 34082069 Free PMC article.
β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development.
Rao S, Yang X, Ohshiro K, Zaidi S, Wang Z, Shetty K, Xiang X, Hassan MI, Mohammad T, Latham PS, Nguyen BN, Wong L, Yu H, Al-Abed Y, Mishra B, Vacca M, Guenigault G, Allison MED, Vidal-Puig A, Benhammou JN, Alvarez M, Pajukanta P, Pisegna JR, Mishra L. Rao S, et al. Among authors: yang x. Sci Transl Med. 2021 Dec 15;13(624):eabk2267. doi: 10.1126/scitranslmed.abk2267. Epub 2021 Dec 15. Sci Transl Med. 2021. PMID: 34910547 Free PMC article.
Aldehydes alter TGF-β signaling and induce obesity and cancer.
Yang X, Bhowmick K, Rao S, Xiang X, Ohshiro K, Amdur RL, Hassan MI, Mohammad T, Crandall K, Cifani P, Shetty K, Lyons SK, Merrill JR, Vegesna AK, John S, Latham PS, Crawford JM, Mishra B, Dasarathy S, Wang XW, Yu H, Wang Z, Huang H, Krainer AR, Mishra L. Yang X, et al. Cell Rep. 2024 Sep 24;43(9):114676. doi: 10.1016/j.celrep.2024.114676. Epub 2024 Aug 31. Cell Rep. 2024. PMID: 39217614 Free article.
72,840 results
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