Papers by Mohammed Alasqah
Clinical Implant Dentistry and Related Research, Mar 20, 2019
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Environmental Toxicology and Pharmacology, Jul 1, 2018
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Clinical Implant Dentistry and Related Research, Dec 13, 2018
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Photodiagnosis and Photodynamic Therapy, Sep 1, 2018
To evaluate the effects of single application of antimicrobial photodynamic therapy (aPDT) as an ... more To evaluate the effects of single application of antimicrobial photodynamic therapy (aPDT) as an adjunct to open flap debridement (OFD) and OFD alone in patients with peri-implantitis (PI). Twenty four patients with PI were divided into 2 groups receiving aPDT with OFD and OFD alone respectively. Peri-implant plaque index (PI), bleeding on probing (BOP), pocket depth (PD) and marginal bone level (MBL) were assessed at baseline, 6 and 12 months post-therapy. Digital periapical radiographs were taken and viewed on a calibrated computer screen using a software for the assessment of MBL. Only single implant from each patient was included in the study protocol (intent to treat analysis). At baseline, peri-implant PI, BOP, PD and MBL were comparable among individuals in aPDT and OFD groups. All patients had localized peri-implant PD ≥5 mm. At 6 months, aPDT and OFD significantly reduced peri-implant PI, BOP, PD and MBL. Similarly, after 12 months post-therapy, both groups reduced PI, BOP, PD and MBL. However, there was no significant difference between aPDT and OFD groups over time. Single application of aPDT as an adjunct to OFD does not provide additional benefit in improving clinical and radiographic peri-implant parameters in peri-implantitis.
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Clinical Implant Dentistry and Related Research, 2018
BackgroundObesity seem to regulate peri‐implant health. It is proposed that peri‐implant crevicul... more BackgroundObesity seem to regulate peri‐implant health. It is proposed that peri‐implant crevicular fluid (PICF) levels of interleukin (IL)‐1β and IL‐6 are higher in obese as compared to nonobese individuals.ObjectiveThe purpose of the present clinico‐laboratory study is to estimate and compare the clinical and radiographic indices and PICF levels of IL‐1β and IL‐6 among obese and nonobese patients.Materials and MethodsFifty patients were divided into two groups (25 obese with ≥27.5 kg/m2 and 25 nonobese with <27.5 kg/m2 individuals). Clinical indices for both periodontal and peri‐implant evaluating plaque index (PI), bleeding on probing (BOP), probing depth (PD), clinical attachment level (CAL), and crestal bone loss (CBL) were recorded around teeth and implants. PICF was collected and assessed for the levels of IL‐1β and IL‐6 using enzyme‐linked immunosorbent assay.ResultsA significant difference was observed in PI and BOP around natural teeth and implants in obese patients, re...
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Journal of periodontology, Jan 12, 2018
It is hypothesized that peri-implant soft tissue inflammation and crestal bone loss (CBL) are hig... more It is hypothesized that peri-implant soft tissue inflammation and crestal bone loss (CBL) are higher around adjacent implants placed in cigarette-smokers compared with never-smokers. The aim of the present 5 years' follow-up retrospective clinical study was to compare the peri-implant soft tissue status and crestal bone loss (CBL) around adjacent implants placed in cigarette-smokers and never-smokers. Cigarette-smokers (Group-1) and never-smokers (Group-2) with adjacent dental implants were included. Demographic information regarding age, gender, duration of smoking (pack years), daily frequency of tooth brushing and most recent visit to a dentist or dental hygienist were recorded using a questionnaire. Information regarding implant dimensions (length × diameter), duration of implants in function, loading protocol (and type of restoration was recorded. Peri-implant plaque index (PI), bleeding on probing (BOP), probing depth (PD) and mesial and distal CBL were measured. P < 0....
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Environmental toxicology and pharmacology, Jan 23, 2018
The aim was to compare the clinical (plaque index [PI], bleeding on probing [BOP], probing pocket... more The aim was to compare the clinical (plaque index [PI], bleeding on probing [BOP], probing pocket depth [PPD] and clinical attachment loss [CAL]) and radiographic (marginal bone loss [MBL]) periodontal parameters and whole salivary cotinine, interleukin (IL)-1β and IL-6 levels among cigarette-smokers, waterpipe-smokers, E-cig users and never-smokers. In total, 154 male individuals (39 cigarette-smokers, 40 waterpipe-smokers, 37 E-cig users and 38 never-smokers) were included. Full mouth PI, BOP, PPD and CAL were measured on all teeth (excluding third molars); and MBL was measured in digital intra-oral radiographs. Unstimulated whole salivary flow rate (UWSFR) and whole salivary cotinine, IL-1β and IL-6 levels were measured. Group comparisons were performed using one way analysis of variance and Bonferroni post-hoc tests. P-values less than 0.05 were considered statistically significant. There was no difference in UWSFR among the groups. Cotinine levels were significantly higher amon...
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Photodiagnosis and photodynamic therapy, Jan 14, 2018
There are no studies that have assessed the effectiveness of antimicrobial photodynamic therapy (... more There are no studies that have assessed the effectiveness of antimicrobial photodynamic therapy (aPDT) in reducing peri-implant inflammatory response in individuals vaping electronic cigarettes (e-cigs). This study explored the effectiveness of aPDT as an adjunct to mechanical debridement (MD) in the treatment of peri-implant mucositis (p-iM) in individuals vaping e-cigs. Vaping individuals with p-iM were divided into 2 groups: (a) Group-I: receiving MD with aPDT (test group); and (b) Group-II: MD only (control group). Peri-implant inflammatory parameters including plaque index (PI), bleeding on probing (BoP), and pocket depth (PD) were assessed at baseline and 12-weeks follow-up. Inter- and intra-group comparisons were made using Mann-Whitney U test and Wilcoxon signed ranks test. P-value < 0.05 was considered significant. Thirty-eight male patients (20 in Group-I and 18 in Group-II) were included. The mean age of vaping individuals in groups I and II were 33.6 ± 2.8 and 35.4 ± ...
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Brazilian oral research, Jan 6, 2018
The aim of the present study was to compare the clinical and radiographic periodontal parameters ... more The aim of the present study was to compare the clinical and radiographic periodontal parameters in prediabetes, type 2 diabetes mellitus (T2DM), and non-diabetic patients. Forty-one patients with prediabetes (Group 1), 43 patients with T2DM (Group 2), and 41 controls (Group 3) were included. Demographic data were recorded using a questionnaire. Full-mouth clinical (plaque index [PI], bleeding on probing [BOP], probing depth [PD], clinical attachment loss [CAL], missing teeth [MT]) and radiographic (marginal bone loss [MBL]) parameters were measured on digital radiographs. In all groups, hemoglobin A1c (HbA1c) levels were also measured. P values less than 0.05 were considered statistically significant. The mean age and HbA1c levels of participants in Groups 1, 2, and 3 were 53.4±3.5, 60.1 ± 0.6, and 56.6 ± 2.5 years and 6.1%, 8.4%, and 4.8%, respectively. The mean duration of prediabetes and T2DM in patients from Groups 1 and 2 were 1.9 ± 0.3 and 3.1 ± 0.5 years, respectively. PI, B...
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Healthcare
This study aimed to evaluate the radiographic reliability in the diagnosis of furcation involveme... more This study aimed to evaluate the radiographic reliability in the diagnosis of furcation involvement in first molars. A total of 52 subjects were included in the current study. Personal history regarding smoking was recorded and a periodontal examination was performed. Pocket depth (PD), clinical attachment level (CAL), gingival recession, and furcation involvement in all first molars were assessed for each patient. Periodontal staging and grading were evaluated using the new classification of periodontal disease. Class II and Class III furcation classification were more frequently observed in radiographs than the Class I furcation; however, no significant differences were observed. Radiographic observation of the furcation was seen more when PD and CAL were >5 mm in all molars. The presence of gingival recession and its relation to the radiographic assessment did not reveal any statistically significant association (p > 0.05) except for tooth #16. The trend of visibility of fu...
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Healthcare
Accomplishing painless endodontic treatment, especially in the mandibular molar region, is challe... more Accomplishing painless endodontic treatment, especially in the mandibular molar region, is challenging. Hence, the aim of the study was to compare the efficacy of 2% lidocaine and 4% articaine when used as supplemental intra-ligamentary (IL) anesthesia in mandibular molars having symptomatic irreversible pulpitis with symptomatic apical periodontitis after failed Inferior Alveolar Nerve Block (IANB) injection. In this prospective study, one-hundred and forty-seven adult patients diagnosed with irreversible pulpitis in a mandibular tooth were included who received IANB with 1.8 mL of 2% lidocaine with 1:100,000 epinephrine. Patients who experienced pain were recorded using the Heft–Parker visual analog scale (HP-VAS score ≥ 55 mm) and received supplement intra-ligament injection with either4% articaine or 2% lidocaine with 1:100,000 epinephrine. Supplementary intra-ligament injections resulted in 82.6% and 91.3% of profound anesthesia in the first molar region for 2% lidocaine and 4%...
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Healthcare
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Journal of Family Medicine and Primary Care, 2019
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Platelet Rich Fibrin (PRF) is considered as a healing biomaterial and is commonly used in implant... more Platelet Rich Fibrin (PRF) is considered as a healing biomaterial and is commonly used in implant and plastic periodontal surgery procedures to enhance bone regeneration and soft-tissue wound healing. Smoking has a negative influence on the healing of soft tissue after periodontal therapy; there is no clear assessment of smokings influence on the healing of bony defects after periodontal treatment. The aims of this study to determine whether the level of A-PRF (FGF-2) is affected by smoking. Blood samples were collected from the Riyadh Elm university (REU) patients (30 total samples). The amount of growth factors released from L-PRF at one day, three days, and seven days, samples were kept at 37◦C in the culture media to allow for growth factor release. Protein quantification was carried out using ELISA. At desired time points, FGF-2 was quantified using prepared ELISA kit according to manufacturer protocol. Absorbance was measured at 450 and 570 nm using a micro plate reader and t...
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Open Access Macedonian Journal of Medical Sciences, 2020
BACKGROUND: Gingival recession has been associated with dentinal hypersensitivity, root caries, a... more BACKGROUND: Gingival recession has been associated with dentinal hypersensitivity, root caries, and esthetic compromise. Root coverage procedures aim at providing both tangible and intangible benefits to the patients. Various procedures have been tried to obtain root coverage of single-rooted teeth. Miller Classes I and II gingival recessions hold out the best promise for root coverage as there is no interdental bone and soft-tissue loss associated with these recessions. AIM: The objective of the study was to evaluate and compare the effectiveness of coronally advanced flap (CAF) with platelet-rich fibrin (PRF) membrane with CAF + connective tissue graft (CTG) on recession coverage. MATERIALS AND METHODS: A total of 16 patients required recession coverage for a single tooth were divided into two groups. The test group received CAF + PRF while the control group got CAF + CTG. Different parameters were taken preoperatively (amount of recession, width, and thickness of attached gingiva...
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Journal of Family Medicine and Primary Care, 2020
Periodontal diseases usually refer to inflammatory disorders that are caused by pathogenic bacter... more Periodontal diseases usually refer to inflammatory disorders that are caused by pathogenic bacteria in the subgingival biofilm in association with impaired host immune response and connective tissue breakdown. The bacterial challenge exacerbates the cytokine production by the gingival epithelium, resulting in an uncontrolled inflammation that leads to tooth loss in adults from different populations. The prevalence of these diseases increases with aging, longer retention of teeth, and increased incidence of obesity and diabetes among the population. The prevalence demonstrates an increasing trend and a correlation with numerous comorbidities. Hence, as a family physician one should have the in-depth knowledge regarding the relationship between obesity and periodontitis to create awareness among people to provide primary care. Thus, it is relevant to develop new methods capable of detecting these diseases in the early stages and following up on their progression.
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Dental, Oral and Craniofacial Research, 2018
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Journal of Dental Research and Review, 2016
Introduction: Halitosis can be tested using two main methods, organoleptic and assessment of vola... more Introduction: Halitosis can be tested using two main methods, organoleptic and assessment of volatile sulfur compounds (VSCs), using an electronic meter like Halimeter. Therefore, the present study was conducted to measure the oral malodor of volunteers by means of the organoleptic method and VSCs monitoring and to evaluate the diagnostic value of the Halimeter in the diagnosis of halitosis. Materials and Methods: A cross-sectional observational study was conducted to compare the two diagnostic aids for halitosis. The study population included 110 volunteers, all males, between the ages of 18 and 45 years selected from academic staff, students, and patients of college. Evaluation and comparison of two main methods for halitosis were done, namely, organoleptic and Halimeter. Specificity, positive predictive value (PPV), negative predictive value (NPV), and disease prevalence were calculated for the sulfide monitor test. Receiver operating characteristic (ROC) curve was used to determine the diagnostic values of Halimeter to differentiate individuals with and without halitosis. Results: The correlation coefficient between VSC grading and organoleptic score (Kendall's tau-b) was −0.1090, which was not significant (P = 0.2170). Sensitivity and specificity of sulfide monitor grades for detecting individuals with and without halitosis were 20.75% and 66.67%, respectively. The PPV for the Halimeter was 36.67%, and the NPV was 47.50%. A total of 48.18% of all subjects were accurately identified and differentiated. The area under the ROC curve was 0.5790 (95% confidence interval: 0.4600-0.6980). Conclusion: In the present study, the Halimeter was not found to have a good correlation with the organoleptic method. However, due to the diverse influencing factors, proof of halitosis should always be obtained with two different methods.
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The Journal of Contemporary Dental Practice, 2017
Introduction Dental caries and obesity are two of the most prevalent health conditions affecting ... more Introduction Dental caries and obesity are two of the most prevalent health conditions affecting children. Relative decrease in corporeal movements, escalating inactive lifestyles, and changes in dietary factors are strongly linked with the increasing incidence of overweight and obesity. Furthermore, obesity increases the risk of chronic disease and dental caries that significantly affects the quality of life of young children. The present study intends to explore the relationship between dental caries and obesity in children in Al-Kharj city, Kingdom of Saudi Arabia. Materials and methods The present descriptive study was designed as a cross-sectional study in which a total of 386 children in the age range of 6 to 12 years from elementary schools of Al-Kharj city and pediatric dental clinics in Prince Sattam Dental College were included. Results Mean decayed filled teeth (DFT) score was found to be considerably higher among obese children. Also, incidence of dental caries in decidu...
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Canadian Journal of Gastroenterology, 2009
BACKGROUND:Helicobacter pyloriis considered to be a pathogen responsible for gastritis and peptic... more BACKGROUND:Helicobacter pyloriis considered to be a pathogen responsible for gastritis and peptic ulcers, and a risk factor for gastric cancer. A periodontal pocket in the teeth of individuals with chronic periodontitis may function as a reservoir forH pylori.OBJECTIVE: The present study was undertaken to evaluate whether the presence ofH pyloriin the dental plaque of patients with and without periodontitis correlates with gastric involvement.METHODS: A total of 101 patients with dyspepsia were included in the present study. Subjects were divided into periodontitis and non-periodontitis groups. For the detection ofH pyloriin dental plaque, samples were collected from two teeth using a periodontal curette. Subgingival plaque was obtained by inserting two sterile paper points into periodontal pockets for 20 s. This was followed by an upper gastrointestinal endoscopy and antral biopsies.RESULTS: Sixty-five per cent of patients had dental plaque positive forH pyloriand more than 50% har...
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Papers by Mohammed Alasqah