"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
| Descriptor ID |
D008070
|
| MeSH Number(s) |
D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".
Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".
This graph shows the total number of publications written about "Lipopolysaccharides" by people in this website by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 14 | 16 | 30 |
| 1996 | 16 | 17 | 33 |
| 1997 | 9 | 10 | 19 |
| 1998 | 14 | 25 | 39 |
| 1999 | 17 | 15 | 32 |
| 2000 | 17 | 26 | 43 |
| 2001 | 16 | 27 | 43 |
| 2002 | 19 | 47 | 66 |
| 2003 | 25 | 40 | 65 |
| 2004 | 23 | 40 | 63 |
| 2005 | 24 | 45 | 69 |
| 2006 | 24 | 44 | 68 |
| 2007 | 18 | 53 | 71 |
| 2008 | 19 | 39 | 58 |
| 2009 | 22 | 72 | 94 |
| 2010 | 19 | 59 | 78 |
| 2011 | 18 | 53 | 71 |
| 2012 | 18 | 53 | 71 |
| 2013 | 20 | 55 | 75 |
| 2014 | 22 | 51 | 73 |
| 2015 | 20 | 45 | 65 |
| 2016 | 19 | 40 | 59 |
| 2017 | 24 | 43 | 67 |
| 2018 | 7 | 46 | 53 |
| 2019 | 17 | 34 | 51 |
| 2020 | 14 | 36 | 50 |
| 2021 | 12 | 39 | 51 |
| 2022 | 5 | 44 | 49 |
| 2023 | 4 | 31 | 35 |
| 2024 | 21 | 15 | 36 |
| 2025 | 1 | 1 | 2 |
Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles.
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Loss of TRPV4 decreases NFκB-mediated myometrial inflammation and prevents preterm labor. FASEB J. 2025 Feb 28; 39(4):e70418.
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IRF1 cooperates with ISGF3 or GAF to form innate immune de novo enhancers in macrophages. Sci Signal. 2025 Jan 07; 18(868):eado8860.
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Molecular profiles of blood from numerous species that differ in sensitivity to acute inflammation. Mol Med. 2024 Dec 28; 30(1):280.
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Ezrin drives adaptation of monocytes to the inflamed lung microenvironment. Cell Death Dis. 2024 Nov 29; 15(11):864.
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Microglia drive diurnal variation in susceptibility to inflammatory blood-brain barrier breakdown. JCI Insight. 2024 Nov 08; 9(21).
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Immunomodulatory activity of omadacycline in vitro and in a murine model of acute lung injury. mSphere. 2024 Nov 21; 9(11):e0067124.
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25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation. J Neuroinflammation. 2024 Oct 05; 21(1):251.
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MDM2 induces pro-inflammatory and glycolytic responses in M1 macrophages by integrating iNOS-nitric oxide and HIF-1α pathways in mice. Nat Commun. 2024 Oct 04; 15(1):8624.
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Repeated LPS induces training and tolerance of microglial responses across brain regions. J Neuroinflammation. 2024 Sep 20; 21(1):233.
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Tropomodulin1 exacerbates inflammatory response in macrophages by negatively regulating LPS-induced TLR4 endocytosis. Cell Mol Life Sci. 2024 Sep 14; 81(1):402.