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2024
Epigenetic Regulation of Drug Metabolism in Aging: Utilizing Epigenetics to Optimize Geriatric Pharmacotherapy
Pharmacogenomics
2024
Potential impact of underlying diseases influencing ADME in nonclinical safety assessment
Food and Chemical Toxicology
2024
Molecular basis of progressive familial intrahepatic cholestasis 3. A proteomics study
BioFactors
2023
Toxicological and histopathological alterations in the heart of young and adult albino rats exposed to mosquito coil smoke
Environmental Science and Pollution Research
2023
Differences in the pharmacokinetics and steady-state blood concentrations of orally administered lenvatinib in adult and juvenile rats
Frontiers in Pharmacology
2023
Intracellular spatiotemporal metabolism in connection to target engagement
Advanced Drug Delivery Reviews
2023
The effect of brain serotonin deficit (TPH2-KO) on the expression and activity of liver cytochrome P450 enzymes in aging male Dark Agouti rats
Pharmacological Reports
2023
The Roles of Lipid Metabolism in the Pathogenesis of Chronic Diseases in the Elderly
Nutrients
2023
Advances in Medical Diagnosis, Treatment, and Care
2023
Acetaminophen for the patent ductus arteriosus: has safety been adequately demonstrated?
Journal of Perinatology
2022
Using liver models generated from human-induced pluripotent stem cells (iPSCs) for evaluating chemical-induced modifications and disease across liver developmental stages
Toxicology in Vitro
2022
The effect of aging on the repeated-dose liver micronucleus assay using diethylnitrosamine
Genes and Environment
2022
Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats
Neurochemistry International
2022
The Effects of AT-533 and AT-533 gel on Liver Cytochrome P450 Enzymes in Rats
European Journal of Drug Metabolism and Pharmacokinetics
2022
Pharmacokinetics of levonorgestrel and etonogestrel in rat or minipig following intravenous, subcutaneous, or intradermal administration
Xenobiotica
2022
A pilot study for the prediction of liver function related scores using breath biomarkers and machine learning
Scientific Reports
2022
Pharmacogenomics in Psychiatry Practice: The Value and the Challenges
International Journal of Molecular Sciences
2022
Pharmacokinetics and transplacental transfer of codeine and codeine metabolites from Papaver somniferum L.
Journal of Ethnopharmacology
2022
CYP3A1 metabolism-based neurotoxicity of strychnine in rat
Toxicology
2022
ROS: Basic Concepts, Sources, Cellular Signaling, and its Implications in Aging Pathways
Oxidative Medicine and Cellular Longevity
2021
Age-and Region-Dependent Disposition of Raloxifene in Rats
Pharmaceutical Research
2021
Ontogeny of Hepatic Transporters and Drug-Metabolizing Enzymes in Humans and in Nonclinical Species
Pharmacological Reviews
2021
Research Progress on Association between Early-Life Exposure to Phthalates and Childhood Asthma
Journal of Biomedical Research & Environmental Sciences
2021
Early onset senescence and cognitive impairment in a murine model of repeated mTBI
Acta Neuropathologica Communications
2021
Acute severe poisoning with disinfectant in senior aged patient-case report and overview of literature considering age influence on treatment decision in alcohol-based intoxications
SAGE Open Medical Case Reports
2021
An age‐related decline in the expression of a red carotenoid‐based ornament in wild birds
Evolution
2021
The Aging Liver: Redox Biology and Liver Regeneration
Antioxidants & Redox Signaling
2021
Thyroid Disruptors: Extrathyroidal Sites of Chemical Action and Neurodevelopmental Outcome—An Examination Using Triclosan and Perfluorohexane Sulfonate
Toxicological Sciences
2021
Methods in Molecular Biology
2021
Serum and Erythrocyte Antioxidant Defense in Colorectal Cancer Patients during Early Postoperative Period: Potential Modifiers and Impact on Clinical Outcomes
Antioxidants
2021
Effects of Short- and Long-Term Soy Protein Feeding on Hepatic Cytochrome P450 Expression in Obese Nonalcoholic Fatty Liver Disease Rat Model
Frontiers in Nutrition
2021
Protective Effect of Curcumin against Sodium Salicylate-Induced Oxidative Kidney Damage, Nuclear Factor-Kappa Dysregulation, and Apoptotic Consequences in Rats
Antioxidants
2020
Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin
Journal of Pharmacy and Pharmacology
2020
Pedro Ximenez sun-dried grape must: a dietary supplement for a healthy longevity
Food & Function
2020
First assessment of POPs and cytochrome P450 expression in Cuvier’s beaked whales (Ziphius cavirostris) skin biopsies from the Mediterranean Sea
Scientific Reports
2020
Changes and sex- and age-related differences in the expression of drug metabolizing enzymes in a KRAS-mutant mouse model of lung cancer
PeerJ
2020
Identification and mutational analyses of KpsF gene containing PxIxIT motif in Aspergillus fumigatus
Journal of King Saud University - Science
2020
Catalpol coordinately regulates phase I and II detoxification enzymes of Triptolide through CAR and NRF2 pathways to reduce Triptolide-induced hepatotoxicity
Biomedicine & Pharmacotherapy
2020
Regulation of CAR and PXR Expression in Health and Disease
Cells
2020
Impact of host and environmental factors on β-glucuronidase enzymatic activity: implications for gastrointestinal serotonin
American Journal of Physiology-Gastrointestinal and Liver Physiology
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