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Kiehntopf et al., 1995 - Google Patents

Ribozymes: Possible New Tools for Treatment of Cancer and Retroviral Diseases?

Kiehntopf et al., 1995

Document ID
7734918924381576709
Author
Kiehntopf M
Brach M
Herrmann F
Publication year
Publication venue
Oncology Research and Treatment

External Links

Snippet

Ribozymes represent an exciting new class of sophisticated antisense molecules as they combine the inherent substrate sequence specificity of complementary nucleic acids with the ability to catalytically degrade and, thus, inactivate susceptible substrate RNAs. This article …
Continue reading at karger.com (other versions)

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
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