[go: up one dir, main page]

Fletcher et al., 1999 - Google Patents

Structure and interactions of the translation initiation factor eIF1

Fletcher et al., 1999

View HTML
Document ID
2184601992631471671
Author
Fletcher C
Pestova T
Hellen C
Wagner G
Publication year
Publication venue
The EMBO journal

External Links

Snippet

eIF1 is a universally conserved translation factor that is necessary for scanning and involved in initiation site selection. We have determined the solution structure of human eIF1 with an N‐terminal His tag using NMR spectroscopy. Residues 29–113 of the native sequence form …
Continue reading at www.embopress.org (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/564—Immunoassay; Biospecific binding assay for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature

Similar Documents

Publication Publication Date Title
Fletcher et al. Structure and interactions of the translation initiation factor eIF1
Chi et al. Solution structure of a conserved C‐terminal domain of p73 with structural homology to the SAM domain
Hatanaka et al. Tertiary structure of destrin and structural similarity between two actin-regulating protein families
Walsh et al. The inhibitor protein of the cAMP-dependent protein kinase
Aihara et al. The N-terminal domain of the human Rad51 protein binds DNA: structure and a DNA binding surface as revealed by NMR
Lin et al. A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies
Safer et al. Thymosin β4 binds actin in an extended conformation and contacts both the barbed and pointed ends
Jacobs et al. Specificity of the HP1 chromo domain for the methylated N‐terminus of histone H3
Szabo et al. A zinc finger‐like domain of the molecular chaperone DnaJ is involved in binding to denatured protein substrates.
Zhou et al. Solution structure of the core NFATC1/DNA complex
Schade et al. Structure–function analysis of the Z‐DNA‐binding domain Zα of dsRNA adenosine deaminase type I reveals similarity to the (α+ β) family of helix–turn–helix proteins
Cahuzac et al. A recurrent RNA‐binding domain is appended to eukaryotic aminoacyl‐tRNA synthetases
Samuels et al. Purification and characterization of a specific RNA polymerase II transcription factor.
Botuyan et al. Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains
Vise et al. NMR chemical shift and relaxation measurements provide evidence for the coupled folding and binding of the p53 transactivation domain
Friedler et al. Modulation of binding of DNA to the C-terminal domain of p53 by acetylation
Bolin et al. NMR structure of a minimized human agouti related protein prepared by total chemical synthesis
Day et al. Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands
Henri et al. Deep structural analysis of RPAP3 and PIH1D1, two components of the HSP90 co-chaperone R2TP complex
Huang et al. Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails
Chan et al. Structural studies of inositol 1, 4, 5-trisphosphate receptor: coupling ligand binding to channel gating
Hidalgo et al. Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain
Agez et al. Structure of the histone chaperone ASF1 bound to the histone H3 C-terminal helix and functional insights
Blüml et al. A small region in phosducin inhibits G‐protein βγ‐subunit function
Li et al. Solution structures, dynamics, and lipid‐binding of the sterile α‐motif domain of the deleted in liver cancer 2