Meng et al., 2025 - Google Patents
Molecular Trojan Based on Membrane‐Mimicking Conjugated Electrolyte for Stimuli‐Responsive Drug ReleaseMeng et al., 2025
- Document ID
- 1816670899728034443
- Author
- Meng Y
- Gao J
- Huang X
- Liu P
- Zhang C
- Zhou P
- Bai Y
- Guo J
- Zhou C
- Li K
- Huang F
- Cao Y
- Publication year
- Publication venue
- Advanced Materials
External Links
Snippet
Enhancing payload encapsulation stability while enabling controlled drug release are both critical objectives in drug delivery systems but are challenging to reconcile. This study introduces a zwitterionic conjugated electrolyte (CE) molecule named Zwit, which acts as a …
- 229940079593 drug 0 title abstract description 27
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
- A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
- A61K47/48169—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying agent being an organic macromolecular compound, i.e. an oligomeric, polymeric, dendrimeric molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Kang et al. | Good steel used in the blade: well‐tailored type‐I photosensitizers with aggregation‐induced emission characteristics for precise nuclear targeting photodynamic therapy | |
| Hu et al. | Rational Design of IR820‐and Ce6‐Based Versatile Micelle for Single NIR Laser–Induced Imaging and Dual‐Modal Phototherapy | |
| Li et al. | Synchronously Manipulating Absorption and Extinction Coefficient of Semiconducting Polymers via Precise Dual‐Acceptor Engineering for NIR‐II Excited Photothermal Theranostics | |
| Zhang et al. | A Versatile prodrug strategy to in situ encapsulate drugs in MOF nanocarriers: a case of cytarabine‐IR820 prodrug encapsulated ZIF‐8 toward chemo‐photothermal therapy | |
| Zheng et al. | Nanoparticles of chlorin dimer with enhanced absorbance for photoacoustic imaging and phototherapy | |
| Yang et al. | 1D coordination polymer nanofibers for low‐temperature photothermal therapy | |
| Duan et al. | Biomimetic nanocomposites cloaked with bioorthogonally labeled glioblastoma cell membrane for targeted multimodal imaging of brain tumors | |
| Guo et al. | Molecular engineering of conjugated polymers for biocompatible organic nanoparticles with highly efficient photoacoustic and photothermal performance in cancer theranostics | |
| Song et al. | Photosensitizer‐conjugated albumin− polypyrrole nanoparticles for imaging‐guided in vivo photodynamic/photothermal therapy | |
| Yu et al. | Porphyrin Nanocage‐Embedded Single‐Molecular Nanoparticles for Cancer Nanotheranostics | |
| Zhou et al. | Programmed multiresponsive vesicles for enhanced tumor penetration and combination therapy of triple‐negative breast cancer | |
| Zhou et al. | Theranostic prodrug vesicles for reactive oxygen species‐triggered ultrafast drug release and local‐regional therapy of metastatic triple‐negative breast cancer | |
| Hameed et al. | Self-assembly of porphyrin-grafted lipid into nanoparticles encapsulating doxorubicin for synergistic chemo-photodynamic therapy and fluorescence imaging | |
| Hou et al. | pH-Sensitive self-assembling nanoparticles for tumor near-infrared fluorescence imaging and chemo–photodynamic combination therapy | |
| Yang et al. | Micelles assembled with carbocyanine dyes for theranostic near-infrared fluorescent cancer imaging and photothermal therapy | |
| Zhang et al. | Surfactant‐stripped micelles of near infrared dye and paclitaxel for photoacoustic imaging guided photothermal‐chemotherapy | |
| Xing et al. | Doxorubicin/gold nanoparticles coated with liposomes for chemo-photothermal synergetic antitumor therapy | |
| Wang et al. | Multi-stimuli responsive nanosystem modified by tumor-targeted carbon dots for chemophototherapy synergistic therapy | |
| Jing et al. | A reduction-responsive polypeptide nanogel encapsulating NIR photosensitizer for imaging guided photodynamic therapy | |
| Wang et al. | Central metal-derived co-assembly of biomimetic GdTPP/ZnTPP porphyrin nanocomposites for enhanced dual-modal imaging-guided photodynamic therapy | |
| Pei et al. | Albumin-bound paclitaxel dimeric prodrug nanoparticles with tumor redox heterogeneity-triggered drug release for synergistic photothermal/chemotherapy | |
| Wang et al. | Improved cancer phototheranostic efficacy of hydrophobic IR780 via parenteral route by association with tetrahedral nanostructured DNA | |
| Wang et al. | Biomimetic HDL nanoparticle mediated tumor targeted delivery of indocyanine green for enhanced photodynamic therapy | |
| Wu et al. | pH-responsive and self-targeting assembly from hyaluronic acid-based conjugate toward all-in-one chemo-photodynamic therapy | |
| He et al. | A Sequential Dual‐Model Strategy Based on Photoactivatable Metallopolymer for On‐Demand Release of Photosensitizers and Anticancer Drugs |