[go: up one dir, main page]

Zhang et al., 2025 - Google Patents

Bioactive DNA hydrogel interfacing with living cells and extracellular vesicles

Zhang et al., 2025

Document ID
18161551458740632891
Author
Zhang R
Liu M
Li H
Huang Y
Nah C
Yao C
Yang D
Publication year
Publication venue
Biomaterials Science

External Links

Snippet

Biological vesicles, such as living cells and extracellular vesicles (EVs) in biological systems, are important agents and regulators of life functions and play an irreplaceable role in physiological processes and disease progression. The maintenance of high bioactivity …
Continue reading at pubs.rsc.org (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells being immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells being immobilised on or in an organic carrier entrapped within the carrier, e.g. gel, hollow fibre
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/30—Macromolecular compounds
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin, zein

Similar Documents

Publication Publication Date Title
Shahbazi et al. DNA hydrogel assemblies: Bridging synthesis principles to biomedical applications
Gačanin et al. Biomedical applications of DNA‐based hydrogels
Fan et al. Engineered extracellular vesicles as intelligent nanosystems for next-generation nanomedicine
Blackman et al. Confinement of therapeutic enzymes in selectively permeable polymer vesicles by polymerization-induced self-assembly (PISA) reduces antibody binding and proteolytic susceptibility
Ansari et al. Poly (N-isopropylacrylamide)-based hydrogels for biomedical applications: A review of the state-of-the-art
Jacob et al. Emerging role of hydrogels in drug delivery systems, tissue engineering and wound management
Bozuyuk et al. Light-triggered drug release from 3D-printed magnetic chitosan microswimmers
Xu et al. Preparation of intelligent DNA hydrogel and its applications in biosensing
Hoffman Stimuli-responsive polymers: Biomedical applications and challenges for clinical translation
Such et al. Engineered hydrogen-bonded polymer multilayers: from assembly to biomedical applications
De Geest et al. The pros and cons of polyelectrolyte capsules in drug delivery
Dong et al. Supramolecular hydrogels: synthesis, properties and their biomedical applications
Wu et al. DNA hydrogels and their derivatives in biomedical engineering applications
Wu et al. Polymerization in living organisms
Zare et al. DNA hydrogels and nanogels for diagnostics, therapeutics, and theragnostics of various cancers
Sharma et al. Selection and role of polymers for designing of a drug carrier
Wang et al. Injectable DNA hydrogel-based local drug delivery and immunotherapy
Chimisso et al. Design of bio-conjugated hydrogels for regenerative medicine applications: from polymer scaffold to biomolecule choice
Askari et al. Cancer immunotherapy using bioengineered micro/nano structured hydrogels
Tian et al. Nucleic acid–based aggregates and their biomedical applications
Di et al. Design, bioanalytical, and biomedical applications of aptamer-based hydrogels
Drachuk et al. Improving the activity of DNA-encoded sensing elements through confinement in silk microcapsules
Wang et al. Logic “AND Gate Circuit”-based gasdermin protein expressing nanoplatform induces tumor-specific pyroptosis to enhance cancer immunotherapy
You et al. Advances in rolling circle amplification (RCA)‐based DNA‐functional materials for cancer diagnosis and therapy
Zhu et al. Intelligent DNA-based hydrogels for bioanalysis and therapeutics