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Feng et al., 2025 - Google Patents

Simultaneous quantification of methotrexate, 7-hydroxymethotrexate and creatinine in serum by LC-MS/MS for predicting delayed elimination

Feng et al., 2025

Document ID
16221295812684798709
Author
Feng Y
Li C
Xia W
Pei Y
Sun C
Cao H
Ji Z
Huang J
Li Y
Publication year
Publication venue
Journal of Pharmaceutical and Biomedical Analysis

External Links

Snippet

High-dose methotrexate (HDMTX) is widely accepted as the first-line chemotherapeutic agent for pediatric acute lymphoblastic leukemia (ALL). However, it exhibits significant pharmacokinetic variability among individuals, which may lead to delayed elimination of …
Continue reading at www.sciencedirect.com (other versions)

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