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Boyd et al., 2017 - Google Patents

EXTH-44. ADDITION OF THE CARBONIC ANHYDRASE IX INHIBITOR SLC-0111 TO TEMOZOLOMIDE EXTENDS SURVIVAL OF MICE BEARING ORTHOTOPIC …

Boyd et al., 2017

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Document ID
11657086429874811919
Author
Boyd N
Walker K
Tran A
Hackney J
McDonald P
Benavides G
Bevensee M
Gillespie Y
Nabors B
Darley-Usmar V
Dedhar S
Hjelmeland A
Publication year
Publication venue
Neuro-oncology

External Links

Snippet

Brain tumor microenvironments characterized by hypoxia, restricted glucose, and acidic stress contain a subset of neoplastic cells that thrive in these environments, identified as brain tumor initiating cells (BTICs). BTICs are resistant to chemo-and radiotherapy, providing …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

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