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Liachko et al., 2014 - Google Patents

GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris

Liachko et al., 2014

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Document ID
10112046140950655635
Author
Liachko I
Youngblood R
Tsui K
Bubb K
Queitsch C
Raghuraman M
Nislow C
Brewer B
Dunham M
Publication year
Publication venue
PLoS genetics

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The well-studied DNA replication origins of the model budding and fission yeasts are A/T- rich elements. However, unlike their yeast counterparts, both plant and metazoan origins are G/C-rich and are associated with transcription start sites. Here we show that an industrially …
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