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WO2004113871A3 - Fluidic circuits for sample preparation including bio-discs and methods relating thereto - Google Patents

Fluidic circuits for sample preparation including bio-discs and methods relating thereto Download PDF

Info

Publication number
WO2004113871A3
WO2004113871A3 PCT/US2004/019569 US2004019569W WO2004113871A3 WO 2004113871 A3 WO2004113871 A3 WO 2004113871A3 US 2004019569 W US2004019569 W US 2004019569W WO 2004113871 A3 WO2004113871 A3 WO 2004113871A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid
discs
sample preparation
methods relating
preparation including
Prior art date
Application number
PCT/US2004/019569
Other languages
French (fr)
Other versions
WO2004113871A2 (en
Inventor
Horacio Kido
James R Norton
James H Coombs
Original Assignee
Nagaoka Kk
Burstein Technologies Inc
Horacio Kido
James R Norton
James H Coombs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagaoka Kk, Burstein Technologies Inc, Horacio Kido, James R Norton, James H Coombs filed Critical Nagaoka Kk
Priority to EP04755618A priority Critical patent/EP1656203A2/en
Publication of WO2004113871A2 publication Critical patent/WO2004113871A2/en
Publication of WO2004113871A3 publication Critical patent/WO2004113871A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0621—Control of the sequence of chambers filled or emptied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0694—Valves, specific forms thereof vents used to stop and induce flow, backpressure valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Centrifugal Separators (AREA)

Abstract

A fluidic circuit for receiving a fluid and separating a component of a fluid from the fluid comprises a separation chamber for receiving the fluid, an air chamber in fluid communication with the separation chamber, and a return channel in fluid communication with the separation chamber. In an advantageous embodiment, the fluidic circuit is subjected to a force, such as a centrifugal force, so that substantially all of the component of the fluid is moved to the return channel while substantially all remaining portions of the fluid are moved to the separation chamber.
PCT/US2004/019569 2003-06-19 2004-06-17 Fluidic circuits for sample preparation including bio-discs and methods relating thereto WO2004113871A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04755618A EP1656203A2 (en) 2003-06-19 2004-06-17 Fluidic circuits for sample preparation including bio-discs and methods relating thereto

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47980303P 2003-06-19 2003-06-19
US60/479,803 2003-06-19

Publications (2)

Publication Number Publication Date
WO2004113871A2 WO2004113871A2 (en) 2004-12-29
WO2004113871A3 true WO2004113871A3 (en) 2005-09-29

Family

ID=33539224

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/019569 WO2004113871A2 (en) 2003-06-19 2004-06-17 Fluidic circuits for sample preparation including bio-discs and methods relating thereto

Country Status (4)

Country Link
US (2) US20050047968A1 (en)
EP (1) EP1656203A2 (en)
TW (1) TW200514981A (en)
WO (1) WO2004113871A2 (en)

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CN101073003B (en) * 2004-12-08 2011-07-06 松下电器产业株式会社 Plate for biological sample analysis
DE102005048233A1 (en) * 2005-10-07 2007-04-12 Albert-Ludwigs-Universität Freiburg Apparatus and method for handling a liquid sample using a siphon structure
US7384798B2 (en) * 2006-10-31 2008-06-10 Hewlett-Packard Development Company, L.P. Method of detecting analytes in a microfluidic sample and a system for performing the same
US8307988B2 (en) 2006-12-11 2012-11-13 Samsung Electronics Co., Ltd. Apparatus and method for separating components
US7857141B2 (en) * 2006-12-11 2010-12-28 Samsung Electronics Co., Ltd. Apparatus and method for separating components
JP5174723B2 (en) * 2009-03-12 2013-04-03 パナソニック株式会社 Analytical device
US9562262B2 (en) 2011-03-08 2017-02-07 UNIVERSITé LAVAL Fluidic centripetal device
AU2012304228B2 (en) 2011-08-30 2016-02-11 National Research Council Of Canada Centrifugally-enhanced capture method and device
CA2756621C (en) * 2011-10-26 2020-07-14 Michael Serpe Gel assembly
GB2516672B (en) * 2013-07-29 2015-05-20 Atlas Genetics Ltd A system and method for expelling liquid from a fluidic cartridge
GB2516675A (en) 2013-07-29 2015-02-04 Atlas Genetics Ltd A valve which depressurises, and a valve system
DE102013219929B4 (en) * 2013-10-01 2015-07-30 Albert-Ludwigs-Universität Freiburg Fluidic module, apparatus and method for aliquoting a fluid
US9759648B2 (en) 2014-07-03 2017-09-12 The Governors Of The University Of Alberta Stimulus responsive polymeric system
TWI550274B (en) * 2014-08-20 2016-09-21 紹興普施康生物科技有限公司 Microfluidics based analyzer and method for operation thereof
DE102014019526B4 (en) * 2014-12-23 2016-10-27 Testo Ag Examination procedure, disk-shaped sample carrier and use of a sample carrier
WO2017066485A1 (en) 2015-10-13 2017-04-20 Landers James P Devices and methods for extraction, separation and thermocycling
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US10369567B2 (en) * 2015-11-04 2019-08-06 International Business Machines Corporation Continuous, capacitance-based monitoring of liquid flows in a microfluidic device
US20200278348A1 (en) * 2017-11-09 2020-09-03 Small Machines Microchip and device for quantitative analysis of antigen, and method for quantitative analysis of antigen using same
CN114453037B (en) * 2021-12-24 2023-08-29 广州万孚生物技术股份有限公司 Homogeneous phase test micro-fluidic chip and detection system

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Also Published As

Publication number Publication date
TW200514981A (en) 2005-05-01
US20050047968A1 (en) 2005-03-03
EP1656203A2 (en) 2006-05-17
WO2004113871A2 (en) 2004-12-29
US20070280859A1 (en) 2007-12-06

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