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KR970702729A - 항-맥관형성 활성과 종양 퇴화 효과를 갖는 상어의 연골 추출물 및 그의 제조 방법(extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof) - Google Patents

항-맥관형성 활성과 종양 퇴화 효과를 갖는 상어의 연골 추출물 및 그의 제조 방법(extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof)

Info

Publication number
KR970702729A
KR970702729A KR1019960706077A KR19960706077A KR970702729A KR 970702729 A KR970702729 A KR 970702729A KR 1019960706077 A KR1019960706077 A KR 1019960706077A KR 19960706077 A KR19960706077 A KR 19960706077A KR 970702729 A KR970702729 A KR 970702729A
Authority
KR
South Korea
Prior art keywords
supernatant
vivo
tumor
activity
extracts
Prior art date
Application number
KR1019960706077A
Other languages
English (en)
Other versions
KR100378787B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR970702729A publication Critical patent/KR970702729A/ko
Application granted granted Critical
Publication of KR100378787B1 publication Critical patent/KR100378787B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
KR1019960706077A 1994-04-28 1995-04-21 항-맥관형성활성과종양퇴화효과를갖는상어의연골추출물및그의제조방법 KR100378787B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23401994A 1994-04-28 1994-04-28
US08/234,019 1994-04-28
US08/384,555 US5618925A (en) 1994-04-28 1995-02-03 Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof
US08/384,555 1995-02-03

Publications (2)

Publication Number Publication Date
KR970702729A true KR970702729A (ko) 1997-06-10
KR100378787B1 KR100378787B1 (ko) 2003-06-19

Family

ID=26927471

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960706077A KR100378787B1 (ko) 1994-04-28 1995-04-21 항-맥관형성활성과종양퇴화효과를갖는상어의연골추출물및그의제조방법

Country Status (24)

Country Link
US (2) US5618925A (ko)
EP (1) EP0759765B1 (ko)
JP (1) JPH09512563A (ko)
KR (1) KR100378787B1 (ko)
CN (2) CN1541656A (ko)
AT (1) ATE224198T1 (ko)
BG (1) BG62954B1 (ko)
BR (1) BR9507552A (ko)
CA (1) CA2188793C (ko)
CZ (1) CZ290520B6 (ko)
DE (1) DE69528258T2 (ko)
DK (1) DK0759765T3 (ko)
ES (1) ES2182900T3 (ko)
FI (1) FI117375B (ko)
HU (1) HU220784B1 (ko)
IS (1) IS1975B (ko)
NO (1) NO317674B1 (ko)
NZ (1) NZ284407A (ko)
PL (1) PL181981B1 (ko)
PT (1) PT759765E (ko)
RO (1) RO114868B1 (ko)
RU (1) RU2156132C2 (ko)
SI (1) SI0759765T1 (ko)
WO (1) WO1995032722A1 (ko)

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US5618925A (en) * 1994-04-28 1997-04-08 Les Laboratories Aeterna Inc. Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof
US6028118A (en) * 1996-08-08 2000-02-22 Les Laboratoires Aeterna Inc. Methods of using extracts of shark cartilage
US6380366B1 (en) * 1994-04-28 2002-04-30 Les Laboratoires Aeterna Inc. Shark cartilage extract:process of making, methods of using and compositions thereof
US6025334A (en) * 1994-04-28 2000-02-15 Les Laboratoires Aeterna Inc. Extracts of shark cartilage having anti-collagenolytic, anti-inflammatory, anti-angiogenic and anti-tumoral activities; process of making, methods of using and compositions thereof
RU2157695C2 (ru) * 1995-02-03 2000-10-20 Ле Лабораториз Аетерна Инк. Экстракты хрящей акулы, способ их получения и применения
US5843920A (en) * 1996-09-16 1998-12-01 Biocell Technology, Llc Anionic saccharides for extraction of anti-angiogenic protein from cartilage
CA2288269A1 (en) * 1997-02-20 1998-08-27 Industrial Research Limited Angiogenesis inhibitors and activators from shark cartilage
BR9808858A (pt) * 1997-03-11 2000-08-01 Aeterna Lab Inc Terapias antitumores compreendendo uma combinação de um extrato de cartilagem e um agente antineoplástico provendo uma alta eficácia e baixos efeitos colaterais tóxicos
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US5840342A (en) * 1997-09-17 1998-11-24 Raithaus; Lawrence R. Shark liver extract for stimulating the immune system
FR2778558B1 (fr) 1998-05-12 2001-02-16 Oreal Utilisation d'inhibiteur de metalloproteinases pour induire et/ou stimuler la croissance des cheveux ou des poils et/ou freiner leur chute
PT1520588E (pt) 1998-07-13 2015-03-31 Univ Texas Usos de anticorpos para amino fosfolípidos para o tratamento do cancro
US6168807B1 (en) 1998-07-23 2001-01-02 Les Laboratoires Aeterna Inc. Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof
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SI1107795T1 (en) 1998-09-04 2003-06-30 The Regents Of The University Of Michigan Thiomolybdate associated with at least one carbohydrate, and its use for preventing or treating diseases characterized by aberrant vascularization, such as cancer, wet type macular degeneration, rheumatoid arthritis
CN1064690C (zh) * 1998-09-10 2001-04-18 中国人民解放军海军医学研究所 鲨鱼软骨血管生成抑制因子及其分离纯化方法
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WO2002096450A1 (en) * 2001-05-30 2002-12-05 Wackvom Limited Compositions containing an active fraction isolated from ganoderma lucidum and methods of use
US20030087830A1 (en) * 2001-06-12 2003-05-08 Eric Dupont Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
US6908627B2 (en) * 2001-06-21 2005-06-21 Mote Marine Laboratory Conditioned media for inhibiting growth of tumor cells
US7309501B2 (en) * 2001-06-21 2007-12-18 Mote Marine Laboratory Conditioned media to inhibit growth of tumor cells
CA2476126A1 (en) 2002-02-15 2003-08-21 Ocean Nutrition Canada Limited Shark cartilage extracts and use thereof for immunomodulation
KR20150021911A (ko) 2002-07-15 2015-03-03 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 포스파티딜에탄올아민에 결합하는 펩타이드, 및 바이러스 감염 및 암을 치료하는데 있어서 이의 용도
US20070010430A1 (en) * 2003-03-20 2007-01-11 Hosokawa Micron Corparation Proteoglycan isolated from cartilaginous fish and process for producing the same
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
ES2223291B1 (es) * 2003-08-06 2006-03-16 Bioiberica, S.A. Nuevo uso terapeutico de condroitin sulfato.
EP2335650B1 (en) 2003-12-11 2012-10-03 Isto Technologies Inc. Particulate cartilage system
CA3031283A1 (en) 2004-01-22 2005-08-04 University Of Miami Topical co-enzyme q10 formulations and methods of use
CN100377741C (zh) * 2004-02-23 2008-04-02 江卫世 注射用复方骨肽及其制备工艺
US20050288796A1 (en) * 2004-06-23 2005-12-29 Hani Awad Native soft tissue matrix for therapeutic applications
US7837740B2 (en) * 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
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US7815926B2 (en) * 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
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US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
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KR101628982B1 (ko) 2015-11-27 2016-06-09 김준혁 항종양 및 면역 증강용 건강식품 조성물
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CN109394786A (zh) * 2018-10-26 2019-03-01 西交利物浦大学 一种抗肿瘤的药物组合物
WO2020203812A1 (ja) * 2019-03-29 2020-10-08 学校法人慶應義塾 魚介類由来成分による低酸素応答制御
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Also Published As

Publication number Publication date
BG62954B1 (bg) 2000-12-29
CZ314196A3 (en) 1997-04-16
AU719118B2 (en) 2000-05-04
NO964547L (no) 1996-12-30
CN1541656A (zh) 2004-11-03
NZ284407A (en) 1998-04-27
US5618925A (en) 1997-04-08
BR9507552A (pt) 1997-08-05
HU9602975D0 (en) 1997-01-28
ES2182900T3 (es) 2003-03-16
FI117375B (fi) 2006-09-29
DK0759765T3 (da) 2003-01-27
HU220784B1 (hu) 2002-05-28
IS4379A (is) 1996-10-25
CA2188793C (en) 2001-01-16
HUT76554A (en) 1997-09-29
JPH09512563A (ja) 1997-12-16
DE69528258T2 (de) 2003-04-17
EP0759765B1 (en) 2002-09-18
WO1995032722A1 (en) 1995-12-07
PL317076A1 (en) 1997-03-03
PT759765E (pt) 2003-02-28
RU2156132C2 (ru) 2000-09-20
PL181981B1 (en) 2001-10-31
KR100378787B1 (ko) 2003-06-19
NO317674B1 (no) 2004-11-29
CZ290520B6 (cs) 2002-08-14
CN1153477A (zh) 1997-07-02
RO114868B1 (ro) 1999-08-30
DE69528258D1 (de) 2002-10-24
NO964547D0 (no) 1996-10-25
BG100941A (en) 1997-07-31
FI964327A (fi) 1996-12-20
CA2188793A1 (en) 1995-12-07
US5985839A (en) 1999-11-16
CN1147305C (zh) 2004-04-28
AU2300195A (en) 1995-12-21
SI0759765T1 (en) 2003-02-28
FI964327A0 (fi) 1996-10-28
ATE224198T1 (de) 2002-10-15
EP0759765A1 (en) 1997-03-05
IS1975B (is) 2005-01-14

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