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JPH07275254A - Medical laser device - Google Patents

Medical laser device

Info

Publication number
JPH07275254A
JPH07275254A JP7016828A JP1682895A JPH07275254A JP H07275254 A JPH07275254 A JP H07275254A JP 7016828 A JP7016828 A JP 7016828A JP 1682895 A JP1682895 A JP 1682895A JP H07275254 A JPH07275254 A JP H07275254A
Authority
JP
Japan
Prior art keywords
fluorescence
lesion
laser
image
laser light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7016828A
Other languages
Japanese (ja)
Other versions
JP2636775B2 (en
Inventor
Kazuo Arakawa
和男 荒川
Reiji Sano
令而 佐野
Iwajiro Senbokutani
岩次郎 仙北谷
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Panasonic Holdings Corp
Original Assignee
Matsushita Electric Industrial Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matsushita Electric Industrial Co Ltd filed Critical Matsushita Electric Industrial Co Ltd
Priority to JP7016828A priority Critical patent/JP2636775B2/en
Publication of JPH07275254A publication Critical patent/JPH07275254A/en
Application granted granted Critical
Publication of JP2636775B2 publication Critical patent/JP2636775B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Radiation-Therapy Devices (AREA)
  • Surgical Instruments (AREA)
  • Endoscopes (AREA)
  • Laser Surgery Devices (AREA)

Abstract

PURPOSE:To enable the accurate recognition of fluorescence from a lesion by providing a filter for intersepting reflected laser beams from the lesion, between a catheter for guiding laser beams to the lesion from a laser beam source and a fluorescence detecting part for detecting fluorescence from the lesion through the catheter. CONSTITUTION:A laser fiber 3 is connected to a laser beam source 19 and formed of an optical fiber or the like for guiding laser beams to a lesion. An image fiber 5 transmitting an observed image and fluorescence is formed of an optical fiber bundle with the tip part provided with an optical system such as an objective lens and with the other end provided with an ocular lens 12. This laser device is provided with an image pickup part formed of an image pickup tube, a solid image pickup element, or the like, for picking up and displaying the observed image transmitted by the image fiber 5, an image display part 17 formed of a cathode-ray tube, a solid display element, or the like. A filter 21 for preventing laser beams from entering an observation system is further provided in front of the observation system.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【産業上の利用分野】本発明はレーザ光により、病巣を
治療する医用レーザ装置に関する。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a medical laser device for treating a lesion with laser light.

【0002】[0002]

【従来の技術】従来より、胃や食道を治療する方法とし
て、レーザ光を用い病巣を蒸散・除去する治療方法が知
られている。
2. Description of the Related Art Heretofore, as a method for treating the stomach and esophagus, there has been known a therapeutic method in which a lesion is evaporated and removed by using a laser beam.

【0003】例えば、励起用レーザ光源と治療用レーザ
光源とからのレーザ光を一本の伝送路を介して病巣に照
射し、励起用レーザにより励起された病巣からの蛍光を
観察して、病巣を確認し、次にレーザ光源を切り替え、
治療用レーザにより病巣を治療する内視鏡(特開昭62
−11440号公報)が知られていた。
For example, a lesion is irradiated with laser light from an excitation laser light source and a therapeutic laser light source through a single transmission path, and fluorescence from the lesion excited by the excitation laser is observed to form a lesion. , Then switch the laser light source,
An endoscope for treating a lesion with a therapeutic laser (Japanese Patent Application Laid-Open No. 62-62160)
No. 11440 gazette) was known.

【0004】[0004]

【発明が解決しようとする課題】しかしながら、上記従
来の技術では、次のような2つの課題があった。
However, the above-mentioned conventional technique has the following two problems.

【0005】第1の課題:病巣からの反射する励起用レ
ーザ光により、蛍光が判別できず、的確に病巣を確認で
きない。
First problem: Fluorescence cannot be discriminated by the laser light for excitation reflected from the lesion, and the lesion cannot be confirmed accurately.

【0006】第2の課題:治療用レーザ光源と励起用レ
ーザ光源とを別に設けなければならず、装置が大型化し
たり、装置が高価になる。
Second problem: The treatment laser light source and the excitation laser light source must be separately provided, which makes the device large and expensive.

【0007】この第1の課題を解決するものとして、励
起用レーザ光によって病巣が発する蛍光をより鮮明に確
認するために、励起用レーザとしてアルゴンイオンレー
ザを用い、蛍光と反射レーザ光の周波数の差を大きく
し、蛍光を透過するフィルターを設けたレーザ診断内視
鏡(特開昭57−89844号公報)が知られており、
また第2の課題を解決するために、本発明者は治療用レ
ーザ光源と励起用レーザ光源とを同じ光源とすることを
考えてきた。
As a solution to the first problem, in order to more clearly confirm the fluorescence emitted from the lesion by the excitation laser light, an argon ion laser is used as the excitation laser and the frequencies of the fluorescence and the reflected laser light are changed. There is known a laser diagnostic endoscope (Japanese Patent Laid-Open No. 57-89844) provided with a filter that increases the difference and transmits fluorescence.
In order to solve the second problem, the inventor of the present invention has considered making the therapeutic laser light source and the excitation laser light source the same light source.

【0008】そして、本発明者は上記2つの課題を同時
に解決しようと考えてきたが、治療用レーザ光源と励起
用レーザ光源とを同じ光源とした場合には、励起用レー
ザ光の波長が、治療用レーザ光と同じとなり、蛍光の周
波数との差を大きくするような自由な選択ができず、レ
ーザ光と蛍光との波長が非常に近いか、もしくは同じ場
合には、蛍光のみを透過するフィルターを設けることは
できなかった。
The present inventor has considered to solve the above two problems at the same time. However, when the therapeutic laser light source and the excitation laser light source are the same light source, the wavelength of the excitation laser light is It becomes the same as the therapeutic laser light, and it is not possible to freely select it so as to increase the difference between the fluorescence frequency and the wavelengths of the laser light and the fluorescence are very close or the same, and only the fluorescence is transmitted. No filter could be installed.

【0009】本発明は上記従来の課題を解決し、病巣か
らの蛍光を確実に確認することのできる医用レーザ装置
を提供することを目的とする。
An object of the present invention is to solve the above-mentioned conventional problems and to provide a medical laser device capable of surely confirming fluorescence from a lesion.

【0010】[0010]

【課題を解決するための手段】上記課題を解決するため
に、本発明の医用レーザ装置は、レーザ光源からのレー
ザ光を病巣に導くカテーテルと、前記病巣からの蛍光を
前記カテーテルを介して検出する蛍光検出部と、前記カ
テーテルと前記蛍光検出部との間に前記病巣からの反射
レーザ光を遮断するフィルターを設けたものである。
In order to solve the above-mentioned problems, a medical laser device of the present invention comprises a catheter for guiding a laser beam from a laser light source to a lesion, and fluorescence from the lesion detected via the catheter. And a filter for blocking the reflected laser light from the lesion is provided between the fluorescence detecting section and the catheter and the fluorescence detecting section.

【0011】[0011]

【作用】上記構成により、病巣部からの蛍光と反射レー
ザ光は、フィルターを通過することにより、反射レーザ
光は遮断される。同時に、反射レーザ光と同じ周波数の
蛍光も遮断されるが、蛍光は一般的に反射レーザ光より
も広い周波数帯域であるので、反射レーザ光と反射数の
異なる蛍光は遮断されずに、蛍光検出部に到達すること
となる。
With the above structure, the fluorescence and the reflected laser light from the lesion portion pass through the filter, and the reflected laser light is blocked. At the same time, the fluorescence of the same frequency as the reflected laser light is also blocked, but since the fluorescence generally has a wider frequency band than the reflected laser light, the fluorescence having a different reflection number from the reflected laser light is not blocked and the fluorescence detection is performed. It will reach the department.

【0012】[0012]

【実施例】以下、本発明の一実施例について、図面を用
いて説明する。
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An embodiment of the present invention will be described below with reference to the drawings.

【0013】第1図は本発明の医用レーザ装置の構成を
示す。治療用レーザ光兼蛍光診断用レーザ光を供給する
レーザ光源19と、レーザ光源19に結合されレーザ光
を病変部へ導光する光ファイバー等よりなるレーザファ
イバー3と、体内の観測視野を照明する照明光源9と、
照明光源9に結合され照明光を観測部へ導光するライト
ガイド6と、観測像および蛍光を伝送する先端部に図示
しない対物レンズ等の光学系を具備し、他端に接眼レン
ズ12を具備する光ファイバー束等よりなるイメージフ
ァイバー5と、イメージファイバー5にて伝送されてき
た観測像を撮像し、表示するための撮像管または個体撮
像素子等よりなる撮像部14およびブラウン管または個
体表示素子等よりなる映像表示部17と、蛍光診断モー
ド時に蛍光を検出部15に導光する可動ミラー13と、
蛍光検出部15よりの信号を処理し、ブラウン管等へ出
力する蛍光表示部16と、各部を制御する制御部18
と、分岐部2およびカテーテル1より構成される。
FIG. 1 shows the configuration of a medical laser device according to the present invention. A laser light source 19 that supplies a laser beam for treatment and a laser beam for fluorescence diagnosis, a laser fiber 3 including an optical fiber or the like that is coupled to the laser light source 19 and guides the laser beam to a lesion, and an illumination that illuminates an observation visual field in the body. Light source 9,
A light guide 6 coupled to an illumination light source 9 for guiding illumination light to an observation section, an optical system such as an objective lens (not shown) at the tip portion for transmitting an observation image and fluorescence, and an eyepiece lens 12 at the other end. Image fiber 5 formed of an optical fiber bundle, an image pickup unit 14 including an image pickup tube or an individual image pickup element for picking up and displaying an observation image transmitted by the image fiber 5, and a cathode ray tube or an individual display element. And a movable mirror 13 that guides the fluorescence to the detection unit 15 in the fluorescence diagnosis mode.
A fluorescent display unit 16 which processes a signal from the fluorescent detection unit 15 and outputs it to a cathode ray tube or the like, and a control unit 18 which controls each unit.
And a branch portion 2 and a catheter 1.

【0014】また、レーザ光が観測系に入光しないよう
にするフィルター21を観測系の前に設ける。
Further, a filter 21 for preventing the laser light from entering the observation system is provided in front of the observation system.

【0015】体内に挿入するカテーテル1はその断面詳
細図を示す第2図を参照するに、可撓性を有する不活性
プラスチック、例えばテフロン、シリコンゴム、ポリエ
チレン等より形成される管状部材20内に、分岐部2を
介してレーザファイバー3と、ライトガイド6と、イメ
ージファイバー5を内設する。
The catheter 1 to be inserted into the body is shown in FIG. 2 which is a detailed cross-sectional view of the catheter 1. The catheter 1 is provided in a tubular member 20 formed of a flexible inert plastic such as Teflon, silicone rubber or polyethylene. A laser fiber 3, a light guide 6 and an image fiber 5 are internally provided via the branching portion 2.

【0016】上記の構成にあって、内視鏡モードで使用
する場合は可動ミラー13を第1図の点線の位置とし、
ライトガイド6、イメージファイバー5を用いた体内の
観測視野の可視域像を映像表示部17に出像して観察す
る。
In the above structure, when used in the endoscope mode, the movable mirror 13 is set to the position shown by the dotted line in FIG.
A visible region image of the observation visual field in the body using the light guide 6 and the image fiber 5 is displayed on the video display unit 17 for observation.

【0017】蛍光診断モードで使用する場合は、制御部
18により、レーザ光源19の出力を弱め、可動ミラー
13を第1図の実線の位置とし、イメージファイバー5
よりの光をフィルター21を経て蛍光検出部15に導光
する。この作用として、レーザ光源19より発せられた
出力の弱いレーザ光は、レーザファイバー3を介してカ
テーテル1先端より病変部に照射される。この照射レー
ザ光により生体組織が傷つけられずに励起され、正常組
織、罹患組織それぞれ特有の蛍光を発光する(第3図参
照)。
When used in the fluorescence diagnostic mode, the output of the laser light source 19 is weakened by the control unit 18, the movable mirror 13 is set to the position shown by the solid line in FIG.
The reflected light is guided to the fluorescence detection unit 15 through the filter 21. As a result of this, the laser light emitted from the laser light source 19 and having a weak output is radiated from the tip of the catheter 1 to the lesion area via the laser fiber 3. This irradiation laser beam excites the living tissue without damaging it, and emits fluorescence peculiar to normal tissue and diseased tissue (see FIG. 3).

【0018】さらに、蛍光強度を増強して診断を容易に
するための手段として、腫瘍に集積しやすいく励起光に
より蛍光を発光する光感受性物質、例えばヘマトポルフ
ィリン誘導体等を生体に取り込ませておき、腫瘍にのみ
集積した段階でその励起光である630nmのレーザ光
を照射し、630〜690nmに分布する強い蛍光を得
る方法がある。
Further, as a means for enhancing the fluorescence intensity and facilitating diagnosis, a photosensitizing substance that easily accumulates in tumor and emits fluorescence by excitation light, such as hematoporphyrin derivative, is incorporated into a living body. There is a method of irradiating a laser beam of 630 nm which is its excitation light at the stage of being accumulated only in a tumor to obtain strong fluorescence distributed in 630 to 690 nm.

【0019】このようにして得られた生体組織または光
感受性物質からの蛍光は、イメージファイバー5にて伝
送され可動ミラー13によりフィルター21に導光され
る。フィルター21は蛍光観察に障害となる強い励起光
をカットする特性を有しており、励起光と同じ波長の蛍
光も遮断されるが、蛍光は一般に励起光よりも広い波長
領域を有しているため、励起光の波長と異なる波長の蛍
光はフィルター21を通過し、蛍光観察を可能にしてい
る。なお、蛍光診断モードの期間は照明光源部よりの照
明光は蛍光観察の障害となるので制御部18よりの信号
により電気的または機械的に遮断される。
The fluorescence from the living tissue or the photosensitizer thus obtained is transmitted by the image fiber 5 and guided to the filter 21 by the movable mirror 13. The filter 21 has a characteristic of cutting off strong excitation light that interferes with fluorescence observation, and also blocks fluorescence of the same wavelength as the excitation light, but the fluorescence generally has a wider wavelength region than the excitation light. Therefore, fluorescence having a wavelength different from the wavelength of the excitation light passes through the filter 21 and enables fluorescence observation. During the period of the fluorescence diagnosis mode, the illumination light from the illumination light source unit interferes with the fluorescence observation, so that it is electrically or mechanically shut off by the signal from the control unit 18.

【0020】病変部をレーザ光で蒸散・除去する場合
は、レーザファイバー3を病変部に照準して治療モード
でレーザ光源19を駆勢する。術中は可動ミラー13を
蛍光診断モードとして治療用レーザ光による病変部から
の蛍光を観察するか、もしくは内視鏡診断モードで病変
部を観察しながら行えるので、正常部位に損傷を与える
危険がなく安全に施術できる。
When the lesion is evaporated and removed by laser light, the laser fiber 3 is aimed at the lesion and the laser light source 19 is driven in the treatment mode. During operation, the movable mirror 13 is set to the fluorescence diagnostic mode to observe the fluorescence from the lesion by the therapeutic laser light, or the endoscopic diagnostic mode can be performed while observing the lesion, so that there is no risk of damaging the normal site. Can be safely operated.

【0021】以上のように、本装置は治療用レーザ光源
と励起用レーザ光源をその出力を制御する制御部18を
設けることにより1台のレーザ光源19にすることがで
き、小型・軽量で安価な医用レーザ装置を提供すること
が可能となった。さらに、観測系の前に反射レーザ光を
遮断するフィルター21を設けることにより、治療時の
病巣像を治療用レーザ光の反射光で妨害されることな
く、また蛍光診断時は励起用レーザ光の反射光に弱い蛍
光がかき消されることなく、精度の高い治療や診断が可
能となる。
As described above, this apparatus can be integrated into a single laser light source 19 by providing the control section 18 for controlling the output of the therapeutic laser light source and the excitation laser light source, which is small, lightweight and inexpensive. It has become possible to provide various medical laser devices. Furthermore, by providing the filter 21 that blocks the reflected laser light in front of the observation system, the lesion image at the time of treatment is not disturbed by the reflected light of the treatment laser light, and at the time of fluorescence diagnosis, the excitation laser light Highly accurate treatment and diagnosis can be performed without the weak fluorescence of reflected light being extinguished.

【0022】[0022]

【発明の効果】以上のように、本発明は1台のレーザ光
源で治療と診断が行え、小型・軽量で安価な医用レーザ
装置を提供するものである。さらに、病巣像ならびに蛍
光像の観測系の前にレーザを遮断するフィルターを設け
ることにより、照射レーザ光の反射光に妨害されること
なく鮮明な画像情報を得ることができ、安全で正確な治
療が可能となる。
INDUSTRIAL APPLICABILITY As described above, the present invention provides a small-sized, lightweight and inexpensive medical laser device that can perform treatment and diagnosis with one laser light source. Furthermore, by installing a filter that shuts off the laser in front of the observation system for the lesion image and the fluorescence image, clear image information can be obtained without being disturbed by the reflected light of the irradiation laser light, and safe and accurate treatment is possible. Is possible.

【図面の簡単な説明】[Brief description of drawings]

【図1】本発明による第1の実施例の構成図FIG. 1 is a configuration diagram of a first embodiment according to the present invention.

【図2】本発明の一実施例の断面図FIG. 2 is a sectional view of an embodiment of the present invention.

【図3】蛍光スペクトルの一例の説明図FIG. 3 is an explanatory diagram of an example of a fluorescence spectrum.

【符号の説明】[Explanation of symbols]

1 カテーテル 2 分岐部 3 レーザファイバー 5 イメージファイバー 6 ライトガイド 9 照明光源 12 接眼レンズ 13 可動ミラー 14 撮像部 15 蛍光検出部 16 蛍光表示部 17 映像表示部 18 制御部 19 レーザ光源 20 管状部材 21 フィルター 1 Catheter 2 Bifurcation 3 Laser Fiber 5 Image Fiber 6 Light Guide 9 Illumination Light Source 12 Eyepiece 13 Movable Mirror 14 Imager 15 Fluorescence Detector 16 Fluorescence Display 17 Video Display 18 Control 19 Laser Source 20 Tubular 21 Filter

Claims (1)

【特許請求の範囲】[Claims] 【請求項1】 レーザ光源からのレーザ光を病巣に導く
カテーテルと、前記病巣からの蛍光を前記カテーテルを
介して検出する蛍光検出部と、前記カテーテルと前記蛍
光検出部との間に前記病巣からの反射レーザ光を遮断す
るフィルターを設けた医用レーザ装置。
1. A catheter that guides laser light from a laser light source to a lesion, a fluorescence detection unit that detects fluorescence from the lesion via the catheter, and a lesion between the catheter and the fluorescence detection unit. Medical laser device provided with a filter for blocking the reflected laser light of.
JP7016828A 1995-02-03 1995-02-03 Medical laser equipment Expired - Lifetime JP2636775B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7016828A JP2636775B2 (en) 1995-02-03 1995-02-03 Medical laser equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7016828A JP2636775B2 (en) 1995-02-03 1995-02-03 Medical laser equipment

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP63058754A Division JPH01232950A (en) 1988-03-11 1988-03-11 Medical laser apparatus

Publications (2)

Publication Number Publication Date
JPH07275254A true JPH07275254A (en) 1995-10-24
JP2636775B2 JP2636775B2 (en) 1997-07-30

Family

ID=11927057

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7016828A Expired - Lifetime JP2636775B2 (en) 1995-02-03 1995-02-03 Medical laser equipment

Country Status (1)

Country Link
JP (1) JP2636775B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003070722A (en) * 2001-09-06 2003-03-11 Pentax Corp Probe and fluorescence diagnostic system
JP2005211272A (en) * 2004-01-29 2005-08-11 Pentax Corp Endoscope device
JP2006223710A (en) * 2005-02-21 2006-08-31 Japan Atomic Energy Agency Ileus tube type small intestine endoscope that can be laser-examined and treated
JP2016214374A (en) * 2015-05-15 2016-12-22 アンリツ株式会社 Laser treatment device and photodynamic treatment device for esophageal cancer
JP2022161023A (en) * 2021-04-07 2022-10-20 ジャイラス エーシーエムアイ インク ディー/ビー/エー オリンパス サージカル テクノロジーズ アメリカ Optical splitter for laser surgical systems with overheating protection

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5789844A (en) * 1980-11-27 1982-06-04 Mochida Pharm Co Ltd Laser diangostic endoscope
JPS63252134A (en) * 1987-04-10 1988-10-19 工業技術院長 Cancer diagnostic apparatus utilizing fluorescence detection

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5789844A (en) * 1980-11-27 1982-06-04 Mochida Pharm Co Ltd Laser diangostic endoscope
JPS63252134A (en) * 1987-04-10 1988-10-19 工業技術院長 Cancer diagnostic apparatus utilizing fluorescence detection

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003070722A (en) * 2001-09-06 2003-03-11 Pentax Corp Probe and fluorescence diagnostic system
JP2005211272A (en) * 2004-01-29 2005-08-11 Pentax Corp Endoscope device
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US8945195B2 (en) 2005-02-21 2015-02-03 Japan Atomic Energy Agency Small bowel endoscope of ileus tube type that enables laser inspection and therapy
JP2016214374A (en) * 2015-05-15 2016-12-22 アンリツ株式会社 Laser treatment device and photodynamic treatment device for esophageal cancer
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