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HUT74588A - Pharmaceutical compositions containing aza spiro compounds acting on the cholinergic system with muscarinic agonist activity - Google Patents

Pharmaceutical compositions containing aza spiro compounds acting on the cholinergic system with muscarinic agonist activity

Info

Publication number
HUT74588A
HUT74588A HU9600126A HU9600126A HUT74588A HU T74588 A HUT74588 A HU T74588A HU 9600126 A HU9600126 A HU 9600126A HU 9600126 A HU9600126 A HU 9600126A HU T74588 A HUT74588 A HU T74588A
Authority
HU
Hungary
Prior art keywords
image
pharmaceutical compositions
compositions containing
agonist activity
spiro compounds
Prior art date
Application number
HU9600126A
Other languages
English (en)
Other versions
HU9600126D0 (en
HU224638B1 (hu
Inventor
Dov Barak
Abraham Fisher
Yishai Karton
Daniele Marciano
Haim Meshulam
Original Assignee
Israel State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Israel State filed Critical Israel State
Publication of HU9600126D0 publication Critical patent/HU9600126D0/hu
Publication of HUT74588A publication Critical patent/HUT74588A/hu
Publication of HU224638B1 publication Critical patent/HU224638B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU9600126A 1993-07-20 1994-07-15 A kolinerg rendszerre ható, muszkarin agonista hatású azaspiroszármazékok és ezeket tartalmazó gyógyszerkészítmények HU224638B1 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/094,855 US5534520A (en) 1990-04-10 1993-07-20 Spiro compounds containing five-membered rings

Publications (3)

Publication Number Publication Date
HU9600126D0 HU9600126D0 (en) 1996-03-28
HUT74588A true HUT74588A (en) 1997-01-28
HU224638B1 HU224638B1 (hu) 2005-12-28

Family

ID=22247578

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9600126A HU224638B1 (hu) 1993-07-20 1994-07-15 A kolinerg rendszerre ható, muszkarin agonista hatású azaspiroszármazékok és ezeket tartalmazó gyógyszerkészítmények

Country Status (25)

Country Link
US (1) US5534520A (hu)
EP (1) EP0711292B1 (hu)
JP (1) JP3802050B2 (hu)
KR (1) KR100341683B1 (hu)
CN (1) CN1129942B (hu)
AT (1) ATE212347T1 (hu)
AU (1) AU696530B2 (hu)
BG (1) BG62774B1 (hu)
BR (1) BR9407088A (hu)
CA (1) CA2167584C (hu)
CZ (1) CZ295929B6 (hu)
DE (1) DE69429724T2 (hu)
DK (1) DK0711292T3 (hu)
ES (1) ES2171458T3 (hu)
FI (1) FI113777B (hu)
HU (1) HU224638B1 (hu)
IL (1) IL110340A (hu)
NO (1) NO310075B1 (hu)
NZ (1) NZ268637A (hu)
PL (1) PL178931B1 (hu)
PT (1) PT711292E (hu)
RO (1) RO117851B1 (hu)
RU (1) RU2129555C1 (hu)
WO (1) WO1995003303A2 (hu)
ZA (1) ZA945284B (hu)

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Also Published As

Publication number Publication date
BG100370A (bg) 1996-11-29
NO310075B1 (no) 2001-05-14
CN1129942A (zh) 1996-08-28
FI960238A (fi) 1996-03-18
RO117851B1 (ro) 2002-08-30
JPH09503491A (ja) 1997-04-08
ES2171458T3 (es) 2002-09-16
DE69429724T2 (de) 2002-08-29
RU2129555C1 (ru) 1999-04-27
NO960225L (no) 1996-03-12
HU9600126D0 (en) 1996-03-28
JP3802050B2 (ja) 2006-07-26
FI113777B (fi) 2004-06-15
KR960703914A (ko) 1996-08-31
AU696530B2 (en) 1998-09-10
FI960238A0 (fi) 1996-01-17
IL110340A (en) 1999-06-20
DE69429724D1 (de) 2002-03-14
NO960225D0 (no) 1996-01-18
DK0711292T3 (da) 2002-05-06
CN1129942B (zh) 2011-08-10
BR9407088A (pt) 1996-08-13
NZ268637A (en) 1998-01-26
ATE212347T1 (de) 2002-02-15
WO1995003303A3 (en) 1995-03-02
CZ295929B6 (cs) 2005-12-14
PT711292E (pt) 2002-07-31
HU224638B1 (hu) 2005-12-28
EP0711292A1 (en) 1996-05-15
PL312684A1 (en) 1996-05-13
CA2167584C (en) 2006-10-24
AU7191594A (en) 1995-02-20
IL110340A0 (en) 1994-10-21
PL178931B1 (pl) 2000-06-30
BG62774B1 (bg) 2000-07-31
KR100341683B1 (ko) 2002-11-30
CA2167584A1 (en) 1995-02-02
US5534520A (en) 1996-07-09
EP0711292B1 (en) 2002-01-23
WO1995003303A2 (en) 1995-02-02
ZA945284B (en) 1995-10-12
CZ18296A3 (en) 1996-07-17

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