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HUT54362A - Process for producing cumarin derivatives and pharmaceutical compositions containing them - Google Patents

Process for producing cumarin derivatives and pharmaceutical compositions containing them

Info

Publication number
HUT54362A
HUT54362A HU904689A HU468990A HUT54362A HU T54362 A HUT54362 A HU T54362A HU 904689 A HU904689 A HU 904689A HU 468990 A HU468990 A HU 468990A HU T54362 A HUT54362 A HU T54362A
Authority
HU
Hungary
Prior art keywords
producing
pharmaceutical compositions
compositions containing
hydrogen
lower alkyl
Prior art date
Application number
HU904689A
Other languages
English (en)
Other versions
HU207510B (en
Inventor
Hiroaki Yanagisawa
Koichi Fujimoto
Yasuo Shimoji
Takuro Kanazaki
Nobuyoshi Iwata
Yoshiko Kubo
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of HUT54362A publication Critical patent/HUT54362A/hu
Publication of HU207510B publication Critical patent/HU207510B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
HU904689A 1989-07-31 1990-07-31 Process for producing cumarine derivatives and pharmaceutical compositions containing cerebral vasodilatators HU207510B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19881789 1989-07-31
JP30955889 1989-11-28

Publications (2)

Publication Number Publication Date
HUT54362A true HUT54362A (en) 1991-02-28
HU207510B HU207510B (en) 1993-04-28

Family

ID=26511193

Family Applications (1)

Application Number Title Priority Date Filing Date
HU904689A HU207510B (en) 1989-07-31 1990-07-31 Process for producing cumarine derivatives and pharmaceutical compositions containing cerebral vasodilatators

Country Status (9)

Country Link
EP (1) EP0411912B1 (hu)
KR (1) KR910002846A (hu)
CN (2) CN1028527C (hu)
AT (1) ATE121395T1 (hu)
CA (1) CA2022236A1 (hu)
DE (1) DE69018726D1 (hu)
HU (1) HU207510B (hu)
IE (1) IE902750A1 (hu)
PT (1) PT94866A (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2190708A1 (en) * 1995-12-08 1997-06-09 Johannes Aebi Aminoalkyl substituted benzo-heterocyclic compounds
HUP0003647A3 (en) * 1997-09-24 2002-12-28 Orion Corp Bisethers of 1-oxa, aza and thianaphthalen-2-ones, their use for producing medicaments, the medicaments and their intermediates
JP2006508339A (ja) 2002-09-20 2006-03-09 プロメガ　コーポレイション シトクロムｐ４５０活性を測定するための発光を利用する方法およびプローブ
CN100358519C (zh) * 2003-05-15 2008-01-02 中国科学院上海有机化学研究所 香豆素类化合物作为制备抗真菌药物的应用
EP2272972A1 (en) 2005-05-31 2011-01-12 Promega Corporation Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
EP2323996B1 (en) 2008-08-18 2014-10-22 Promega Corporation Luminogenic compounds and methods to detect cytochrome p450 3a enzymes
CN103788044B (zh) * 2008-11-28 2016-09-14 中国医学科学院药物研究所 硝克柳胺化合物晶i型、其制法和其药物组合物与用途
EP3099683B1 (en) 2014-01-29 2020-08-05 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
CN105524034B (zh) * 2015-03-27 2018-08-17 北京大学 香豆素衍生物的制备、药理作用及治疗脑缺血的应用
EP3831820A1 (en) * 2019-12-05 2021-06-09 ETH Zurich Compounds and methods for amine oxidase imaging
CN114920722B (zh) * 2021-06-02 2024-03-08 何黎琴 一种7-羟基-3-乙酰基香豆素肟类化合物、其制备方法及医药用途
CN113292526A (zh) * 2021-06-16 2021-08-24 锦州九泰药业有限责任公司 一种高收率延通心原料药的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6013788A (ja) * 1983-07-05 1985-01-24 Yamanouchi Pharmaceut Co Ltd 新規なクマリン誘導体
DE3427985A1 (de) * 1984-07-28 1986-01-30 Boehringer Mannheim Gmbh, 6800 Mannheim Neue 2h-l-benzopyran-2-on-derivate, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US4701456A (en) * 1984-09-19 1987-10-20 Warner-Lambert Company Aminoalkoxybenzopyranones as antipsychotic and anxiolytic agents

Also Published As

Publication number Publication date
CN1107151A (zh) 1995-08-23
CN1049662A (zh) 1991-03-06
CN1028527C (zh) 1995-05-24
PT94866A (pt) 1991-03-20
EP0411912B1 (en) 1995-04-19
HU207510B (en) 1993-04-28
EP0411912A2 (en) 1991-02-06
ATE121395T1 (de) 1995-05-15
CA2022236A1 (en) 1991-02-01
IE902750A1 (en) 1991-02-27
EP0411912A3 (en) 1991-09-11
KR910002846A (ko) 1991-02-26
DE69018726D1 (de) 1995-05-24

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee