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HUT50461A - Process for producing imidazole derivatives inhibiting dopamin-beta-hydroxylase and pharmaceutical compositions comprising such compounds - Google Patents

Process for producing imidazole derivatives inhibiting dopamin-beta-hydroxylase and pharmaceutical compositions comprising such compounds

Info

Publication number
HUT50461A
HUT50461A HU874557A HU455787A HUT50461A HU T50461 A HUT50461 A HU T50461A HU 874557 A HU874557 A HU 874557A HU 455787 A HU455787 A HU 455787A HU T50461 A HUT50461 A HU T50461A
Authority
HU
Hungary
Prior art keywords
dopamin
hydroxylase
beta
compounds
pharmaceutical compositions
Prior art date
Application number
HU874557A
Other languages
English (en)
Other versions
HU204037B (en
Inventor
Joseph A Finkelstein
James S Frazee
Carl Kaiser
Lawrence I Kruse
Thomas B Leonard
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of HUT50461A publication Critical patent/HUT50461A/hu
Publication of HU204037B publication Critical patent/HU204037B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
HU874557A 1986-08-18 1987-08-17 Process for producing dopamine-beta-hydroxylase inhibiting imidazole derivatives and pharmaceutical compositions comprising such compounds HU204037B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89816586A 1986-08-18 1986-08-18
PCT/US1987/002011 WO1988001267A1 (en) 1986-08-18 1987-08-17 DOPAMINE-ss-HYDROXYLASE INHIBITORS

Publications (2)

Publication Number Publication Date
HUT50461A true HUT50461A (en) 1990-02-28
HU204037B HU204037B (en) 1991-11-28

Family

ID=25409053

Family Applications (2)

Application Number Title Priority Date Filing Date
HU874557A HU204037B (en) 1986-08-18 1987-08-17 Process for producing dopamine-beta-hydroxylase inhibiting imidazole derivatives and pharmaceutical compositions comprising such compounds
HU911945A HU911945D0 (en) 1986-08-18 1987-08-17 Process for the production of intermediers of anti dopamin-betha-hydroxylase

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU911945A HU911945D0 (en) 1986-08-18 1987-08-17 Process for the production of intermediers of anti dopamin-betha-hydroxylase

Country Status (15)

Country Link
EP (2) EP0260814B1 (hu)
CN (1) CN87105734A (hu)
AT (1) ATE72430T1 (hu)
AU (1) AU7910287A (hu)
DE (1) DE3776613D1 (hu)
DK (1) DK210488A (hu)
ES (1) ES2038185T3 (hu)
GR (1) GR3004345T3 (hu)
HU (2) HU204037B (hu)
NZ (1) NZ221427A (hu)
PH (1) PH23530A (hu)
PT (1) PT85547B (hu)
WO (1) WO1988001267A1 (hu)
ZA (1) ZA876073B (hu)
ZW (1) ZW15387A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4835154A (en) * 1987-06-01 1989-05-30 Smithkline Beckman Corporation 1-aralykyl-5-piperazinylmethyl-2-mercaptoimidazoles and 2-alkylthioimidazoles and their use as dopamine-βhydroxylase inhibitors
US4882348A (en) * 1987-12-29 1989-11-21 Smithkline Beckman Corporation 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors
FR2928544A1 (fr) * 2008-03-17 2009-09-18 Oreal Utilisation d'inhibiteurs de la dopamine-beta hydroxylase pour la pigmentation capillaire.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors
US4532331A (en) * 1983-04-12 1985-07-30 Smithkline Beckman Corporation 1-Benzyl-2-aminomethyl imidazole derivatives

Also Published As

Publication number Publication date
EP0260814B1 (en) 1992-02-05
PT85547A (pt) 1988-08-17
ZW15387A1 (en) 1987-11-18
EP0288488A1 (en) 1988-11-02
CN87105734A (zh) 1988-02-24
EP0288488A4 (en) 1990-09-12
DK210488D0 (da) 1988-04-18
NZ221427A (en) 1990-12-21
ATE72430T1 (de) 1992-02-15
GR3004345T3 (hu) 1993-03-31
ZA876073B (en) 1988-08-31
ES2038185T3 (es) 1993-07-16
HU911945D0 (en) 1991-12-30
HU204037B (en) 1991-11-28
AU7910287A (en) 1988-03-08
DE3776613D1 (de) 1992-03-19
EP0260814A1 (en) 1988-03-23
PT85547B (pt) 1995-03-01
DK210488A (da) 1988-04-18
WO1988001267A1 (en) 1988-02-25
PH23530A (en) 1989-08-25

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