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HK1211219A1 - Formulations with reduced oxidation - Google Patents

Formulations with reduced oxidation Download PDF

Info

Publication number
HK1211219A1
HK1211219A1 HK15112071.0A HK15112071A HK1211219A1 HK 1211219 A1 HK1211219 A1 HK 1211219A1 HK 15112071 A HK15112071 A HK 15112071A HK 1211219 A1 HK1211219 A1 HK 1211219A1
Authority
HK
Hong Kong
Prior art keywords
formulation
protein
antibody
oxidation
compound
Prior art date
Application number
HK15112071.0A
Other languages
English (en)
Chinese (zh)
Other versions
HK1211219B (zh
Inventor
Sreedhara Alavattam
Mary MALLANEY
Parbir GREWAL
Original Assignee
霍夫曼-拉罗奇有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 霍夫曼-拉罗奇有限公司 filed Critical 霍夫曼-拉罗奇有限公司
Publication of HK1211219A1 publication Critical patent/HK1211219A1/xx
Publication of HK1211219B publication Critical patent/HK1211219B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Lubricants (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15112071.0A 2013-03-13 2014-03-13 氧化降低的配製劑 HK1211219B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361780845P 2013-03-13 2013-03-13
US61/780,845 2013-03-13
US201361909813P 2013-11-27 2013-11-27
US61/909,813 2013-11-27
PCT/US2014/026841 WO2014160495A1 (fr) 2013-03-13 2014-03-13 Formulations ayant une oxydation réduite

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK42020001599.8A Division HK40011551A (en) 2013-03-13 2015-12-08 Formulations with reduced oxidation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK42020001599.8A Addition HK40011551A (en) 2013-03-13 2015-12-08 Formulations with reduced oxidation

Publications (2)

Publication Number Publication Date
HK1211219A1 true HK1211219A1 (en) 2016-05-20
HK1211219B HK1211219B (zh) 2020-02-07

Family

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Also Published As

Publication number Publication date
KR20150130397A (ko) 2015-11-23
AU2014243700B2 (en) 2019-01-24
CA3113172A1 (en) 2014-10-02
SI2968466T1 (sl) 2018-10-30
CN110075293A (zh) 2019-08-02
EP2968466B1 (fr) 2018-07-25
NZ751543A (en) 2020-09-25
JP2018150317A (ja) 2018-09-27
LT2968466T (lt) 2018-10-10
AU2021201366A1 (en) 2021-03-18
WO2014160495A1 (fr) 2014-10-02
EP2968466A1 (fr) 2016-01-20
RU2015143548A (ru) 2017-04-20
BR112015022484A2 (pt) 2017-07-18
IL269947A (fr) 2019-12-31
ZA201906057B (en) 2022-04-28
CA2904166C (fr) 2021-05-18
MX2019013560A (es) 2020-01-20
MX2015011432A (es) 2016-04-27
HUE039948T2 (hu) 2019-02-28
IL269947B (en) 2022-08-01
IL240933B (en) 2019-10-31
RS57813B1 (sr) 2018-12-31
IL240933A0 (en) 2015-11-30
MX369671B (es) 2019-11-15
RU2707092C2 (ru) 2019-11-22
KR102237885B1 (ko) 2021-04-07
JP6389236B2 (ja) 2018-09-12
CN104968362B (zh) 2018-12-14
CA2904166A1 (fr) 2014-10-02
SG11201507043SA (en) 2015-10-29
AU2019202464A1 (en) 2019-05-02
AU2019202464B2 (en) 2020-12-10
SG10201705525VA (en) 2017-08-30
JP2020164531A (ja) 2020-10-08
HRP20181504T1 (hr) 2018-11-02
MY174679A (en) 2020-05-06
DK2968466T3 (en) 2018-10-22
PT2968466T (pt) 2018-10-22
PL2968466T3 (pl) 2018-11-30
JP2016520521A (ja) 2016-07-14
EP2968466A4 (fr) 2016-10-26
ES2688895T3 (es) 2018-11-07
ZA201506876B (en) 2019-12-18
MY199135A (en) 2023-10-17
NZ711566A (en) 2020-06-26
CN104968362A (zh) 2015-10-07
AU2014243700A1 (en) 2015-10-08

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