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HK1123803A1 - Novel pyridazine compound and use thereof - Google Patents

Novel pyridazine compound and use thereof Download PDF

Info

Publication number
HK1123803A1
HK1123803A1 HK09103622.1A HK09103622A HK1123803A1 HK 1123803 A1 HK1123803 A1 HK 1123803A1 HK 09103622 A HK09103622 A HK 09103622A HK 1123803 A1 HK1123803 A1 HK 1123803A1
Authority
HK
Hong Kong
Prior art keywords
compound
acid
hcv
formula
fatty acid
Prior art date
Application number
HK09103622.1A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1123803B (en
Inventor
Steven S. Bondy
Terrence C. Dahl
David A. Oare
Reza Oliyai
Winston C. Tse
Vahid Zia
Original Assignee
Gilead Sciences, Inc.
K.U. Leuven Research And Development
Gerhard Puerstinger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences, Inc., K.U. Leuven Research And Development, Gerhard Puerstinger filed Critical Gilead Sciences, Inc.
Publication of HK1123803A1 publication Critical patent/HK1123803A1/en
Publication of HK1123803B publication Critical patent/HK1123803B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK09103622.1A 2006-07-07 2007-07-06 Novel pyridazine compound and use thereof HK1123803B (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US81928906P 2006-07-07 2006-07-07
US60/819,289 2006-07-07
US83240306P 2006-07-21 2006-07-21
US60/832,403 2006-07-21
US83276906P 2006-07-24 2006-07-24
US60/832,769 2006-07-24
PCT/US2007/015553 WO2008005519A2 (en) 2006-07-07 2007-07-06 Novel pyridazine compound and use thereof

Publications (2)

Publication Number Publication Date
HK1123803A1 true HK1123803A1 (en) 2009-06-26
HK1123803B HK1123803B (en) 2010-05-28

Family

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Also Published As

Publication number Publication date
NZ574312A (en) 2012-02-24
CA2656415C (en) 2012-05-22
RS51336B (en) 2011-02-28
CY1112107T1 (el) 2015-11-04
SI2038275T1 (sl) 2010-06-30
AU2007269614A1 (en) 2008-01-10
US8569487B2 (en) 2013-10-29
EP2038275B1 (en) 2010-01-06
EP2038275A2 (en) 2009-03-25
DK2038275T3 (da) 2010-05-10
HRP20090078A2 (en) 2009-06-30
ATE454384T1 (de) 2010-01-15
AR061969A1 (es) 2008-08-10
US7754720B2 (en) 2010-07-13
SG175604A1 (en) 2011-11-28
US7956184B2 (en) 2011-06-07
TW200811180A (en) 2008-03-01
EA200900156A1 (ru) 2009-06-30
AP3430A (en) 2015-09-30
JP4958974B2 (ja) 2012-06-20
AP2008004717A0 (en) 2008-12-31
WO2008005519A3 (en) 2008-04-24
MX2009000235A (es) 2009-01-23
IL195528A (en) 2014-07-31
WO2008005519A2 (en) 2008-01-10
US20080199427A1 (en) 2008-08-21
KR101143596B1 (ko) 2012-05-11
TWI360549B (en) 2012-03-21
PL2038275T3 (pl) 2010-08-31
HRP20100180T1 (hr) 2010-06-30
ES2339298T3 (es) 2010-05-18
DE602007004220D1 (de) 2010-02-25
US20100063059A1 (en) 2010-03-11
IL195528A0 (en) 2009-09-01
KR20090028813A (ko) 2009-03-19
CA2656415A1 (en) 2008-01-10
PT2038275E (pt) 2010-04-08
US20100152444A1 (en) 2010-06-17
CN102617571B (zh) 2015-06-10
CN102617571A (zh) 2012-08-01
JP2009542692A (ja) 2009-12-03
EA019452B1 (ru) 2014-03-31
NO20090595L (no) 2009-04-07
AU2007269614B2 (en) 2011-09-08

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150706