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HK1068884A1 - 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione benzenesulfonate; process for its preparation; polymorphs i, ii and iii thereof; and its use as pharmaceutical active ingredient - Google Patents

5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione benzenesulfonate; process for its preparation; polymorphs i, ii and iii thereof; and its use as pharmaceutical active ingredient Download PDF

Info

Publication number
HK1068884A1
HK1068884A1 HK05101352A HK05101352A HK1068884A1 HK 1068884 A1 HK1068884 A1 HK 1068884A1 HK 05101352 A HK05101352 A HK 05101352A HK 05101352 A HK05101352 A HK 05101352A HK 1068884 A1 HK1068884 A1 HK 1068884A1
Authority
HK
Hong Kong
Prior art keywords
thiazolidine
pyridyl
benzyl
ethoxy
methyl
Prior art date
Application number
HK05101352A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1068884B (en
Inventor
Andrew Simon Craig
Michael John Millan
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0127934A external-priority patent/GB0127934D0/en
Priority claimed from GB0127937A external-priority patent/GB0127937D0/en
Priority claimed from GB0127935A external-priority patent/GB0127935D0/en
Priority claimed from GB0127936A external-priority patent/GB0127936D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of HK1068884A1 publication Critical patent/HK1068884A1/en
Publication of HK1068884B publication Critical patent/HK1068884B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK05101352.5A 2001-11-21 2002-11-21 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione benzenesulfonate; process for its preparation; polymorphs i, ii and iii thereof; and its use as pharmaceutical active ingredient HK1068884B (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0127934A GB0127934D0 (en) 2001-11-21 2001-11-21 Novel compounds
GB0127937.1 2001-11-21
GB0127937A GB0127937D0 (en) 2001-11-21 2001-11-21 Novel compounds
GB0127936.3 2001-11-21
GB0127935A GB0127935D0 (en) 2001-11-21 2001-11-21 Novel compounds
GB0127936A GB0127936D0 (en) 2001-11-21 2001-11-21 Novel compounds
GB0127935.5 2001-11-21
GB0127934.8 2001-11-21
PCT/GB2002/005232 WO2003045946A1 (en) 2001-11-21 2002-11-21 5-(4-(2-(n-methyl-n-(2-pyridil) amino) ethoxy) benzyl) thiazolidine-2, 4-dione benzenesulfonate; process for its preparation; polymorphs i, ii and iii thereof; and its use as pharmaceutical active ingredient

Publications (2)

Publication Number Publication Date
HK1068884A1 true HK1068884A1 (en) 2005-05-06
HK1068884B HK1068884B (en) 2007-10-26

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Also Published As

Publication number Publication date
WO2003045946A1 (en) 2003-06-05
DK1448559T3 (da) 2007-04-30
DE60217168T2 (de) 2007-10-04
JP2005513038A (ja) 2005-05-12
SI1448559T1 (sl) 2007-06-30
AU2002343050A1 (en) 2003-06-10
CN1612875A (zh) 2005-05-04
CN100390170C (zh) 2008-05-28
CY1106397T1 (el) 2011-10-12
PT1448559E (pt) 2007-03-30
EP1448559A1 (en) 2004-08-25
DE60217168D1 (de) 2007-02-08
ATE349444T1 (de) 2007-01-15
EP1448559B1 (en) 2006-12-27
KR20040062963A (ko) 2004-07-09
ES2278977T3 (es) 2007-08-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20101121