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HK1009587A1 - Compositions for inhalation - Google Patents

Compositions for inhalation Download PDF

Info

Publication number
HK1009587A1
HK1009587A1 HK98110333A HK98110333A HK1009587A1 HK 1009587 A1 HK1009587 A1 HK 1009587A1 HK 98110333 A HK98110333 A HK 98110333A HK 98110333 A HK98110333 A HK 98110333A HK 1009587 A1 HK1009587 A1 HK 1009587A1
Authority
HK
Hong Kong
Prior art keywords
polypeptide
enhancer
composition
hormone
less
Prior art date
Application number
HK98110333A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1009587B (en
Inventor
Goran Erik Backstrom Kjell
Magnus Olof Dahlback Carl
Edman Peter
Charlotte Birgit Johansson Ann
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9302198A external-priority patent/SE9302198D0/xx
Priority claimed from SE9400371A external-priority patent/SE9400371L/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1009587A1 publication Critical patent/HK1009587A1/en
Publication of HK1009587B publication Critical patent/HK1009587B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
HK98110333.8A 1993-06-24 1994-06-23 Compositions for inhalation HK1009587B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE9302198A SE9302198D0 (sv) 1993-06-24 1993-06-24 Powder preparation for inhalation
SE9302198 1993-06-24
SE9400371A SE9400371L (sv) 1994-02-04 1994-02-04 Kompositioner för inhalation
SE9400371 1994-02-04
PCT/SE1994/000634 WO1995000128A1 (en) 1993-06-24 1994-06-23 Compositions for inhalation

Publications (2)

Publication Number Publication Date
HK1009587A1 true HK1009587A1 (en) 1999-06-04
HK1009587B HK1009587B (en) 2002-05-03

Family

ID=

Also Published As

Publication number Publication date
EP0706383B1 (en) 2001-09-26
DE69428442T2 (de) 2002-07-11
HU226474B1 (en) 2009-01-28
KR100372674B1 (ko) 2003-05-12
CN1127471A (zh) 1996-07-24
EG21484A (en) 2001-11-28
CA2166109A1 (en) 1995-01-05
JP2006089497A (ja) 2006-04-06
IL110085A0 (en) 1994-10-07
PT706383E (pt) 2002-03-28
PL312210A1 (en) 1996-04-01
SA94150060B1 (ar) 2005-05-31
IS4179A (is) 1994-12-25
SK160295A3 (en) 1997-03-05
EP0706383A1 (en) 1996-04-17
EE03222B1 (et) 1999-10-15
NO955227D0 (no) 1995-12-21
CZ287656B6 (en) 2001-01-17
SK283253B6 (sk) 2003-04-01
CZ339395A3 (en) 1996-05-15
AU692781B2 (en) 1998-06-18
HU9503660D0 (en) 1996-02-28
WO1995000128A1 (en) 1995-01-05
ATE206046T1 (de) 2001-10-15
HUT75066A (en) 1997-03-28
AU7090294A (en) 1995-01-17
US5952008A (en) 1999-09-14
CN1116030C (zh) 2003-07-30
NZ268138A (en) 1997-10-24
UA48111C2 (uk) 2002-08-15
BR9406908A (pt) 1996-04-02
CA2166109C (en) 2004-12-14
DK0706383T3 (da) 2001-12-10
NO955227L (no) 1996-02-20
IS1796B (is) 2001-12-31
MX9404762A (es) 1995-01-31
NO313080B1 (no) 2002-08-12
ES2162865T3 (es) 2002-01-16
FI111909B (fi) 2003-10-15
IL110085A (en) 2001-06-14
PL178261B1 (pl) 2000-03-31
FI956228A0 (fi) 1995-12-22
FI956228L (fi) 1995-12-22
JPH09500621A (ja) 1997-01-21
DE69428442D1 (de) 2001-10-31
MY114125A (en) 2002-08-30

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20120623