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EP1718894B1 - Fluid conduit connector apparatus - Google Patents

Fluid conduit connector apparatus Download PDF

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Publication number
EP1718894B1
EP1718894B1 EP05713934A EP05713934A EP1718894B1 EP 1718894 B1 EP1718894 B1 EP 1718894B1 EP 05713934 A EP05713934 A EP 05713934A EP 05713934 A EP05713934 A EP 05713934A EP 1718894 B1 EP1718894 B1 EP 1718894B1
Authority
EP
European Patent Office
Prior art keywords
connector
fluid
valve
port
coupling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP05713934A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1718894A1 (en
Inventor
Christopher Tesluk
Malcolm Bock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covidien LP
Original Assignee
Tyco Healthcare Group LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/784,639 external-priority patent/US7490620B2/en
Priority claimed from US10/784,607 external-priority patent/US7871387B2/en
Priority claimed from US10/784,604 external-priority patent/US7282038B2/en
Priority claimed from US10/784,323 external-priority patent/US7354410B2/en
Application filed by Tyco Healthcare Group LP filed Critical Tyco Healthcare Group LP
Publication of EP1718894A1 publication Critical patent/EP1718894A1/en
Application granted granted Critical
Publication of EP1718894B1 publication Critical patent/EP1718894B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A61H23/04—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with hydraulic or pneumatic drive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H9/00—Pneumatic or hydraulic massage
    • A61H9/005—Pneumatic massage
    • A61H9/0078—Pneumatic massage with intermittent or alternately inflated bladders or cuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/16—Physical interface with patient
    • A61H2201/1602—Physical interface with patient kind of interface, e.g. head rest, knee support or lumbar support
    • A61H2201/1645—Physical interface with patient kind of interface, e.g. head rest, knee support or lumbar support contoured to fit the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/16—Physical interface with patient
    • A61H2201/1683—Surface of interface
    • A61H2201/169—Physical characteristics of the surface, e.g. material, relief, texture or indicia
    • A61H2201/1697—Breathability of the material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5002—Means for controlling a set of similar massage devices acting in sequence at different locations on a patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5007—Control means thereof computer controlled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5058—Sensors or detectors
    • A61H2201/5071—Pressure sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2205/00—Devices for specific parts of the body
    • A61H2205/06—Arms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2205/00—Devices for specific parts of the body
    • A61H2205/10—Leg
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2205/00—Devices for specific parts of the body
    • A61H2205/12—Feet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2209/00—Devices for avoiding blood stagnation, e.g. Deep Vein Thrombosis [DVT] devices

Definitions

  • the present disclosure generally relates to the field of fluid conduit connectors for application to multiple fluid line systems and more particularly to fluid line connectors having a valved port.
  • DVT deep vein thrombosis
  • peripheral edema Medical conditions that form clots in the blood, such as deep vein thrombosis (DVT) and peripheral edema, are a major concern to immobile medical patients. Such patients include those undergoing surgery, anesthesia, extended periods of bed rest, etc. These blood clotting conditions generally occur in the deep veins of the lower extremities and/or pelvis. These veins, such as the iliac, femoral, popiteal and tibial return deoxygenated blood to the heart. When blood circulation in these veins is retarded due to illness, injury or inactivity, there is a tendency for blood to accumulate or pool. A static pool of blood provides an ideal environment for dangerous clot formations. A major risk associated with this condition is interference with cardiovascular circulation. Most seriously, a fragment of the blood clot can break loose and migrate. A pulmonary embolism can form a potentially life-threatening blockage in a main pulmonary artery.
  • Sequential compression devices consist of an air pump connected to a disposable wraparound pad by a series of fluid conduits such as air tubes, for example.
  • the wraparound pad is placed around the patient's leg. Air is then forced into different parts of the wraparound pad in sequence, creating pressure around the calves and improving venous return.
  • These known devices suffer from various drawbacks due to their bulk and cumbersome nature of use. These drawbacks cause patient discomfort, reduce compliance and can prevent mobility of the patient as recovery progresses after surgery. It would be desirable to overcome the disadvantages of such known devices.
  • U.S. Patent Application Serial No. 10/784,607 filed on February 23, 2004 and entitled Compression Apparatus, of which priority is claimed, discloses an exemplary sequential compression apparatus that overcomes the disadvantages and drawbacks of the prior art by reducing bulk and improving comfort and compliance to a patient.
  • This sequential compression apparatus includes a removable portion of a compression sleeve (wraparound pad) and a valve connector that facilitates coupling of the removable portion from a pressurized fluid source.
  • a predetermined fluid pressure is supplied to each of a plurality of tubes to the apparatus according to a predetermined timing sequence. Fluid pressure feedback information is acquired to ensure proper operation of the apparatus. Closure of a valve in the valve connector prevents fluid leakage when the removable portion and corresponding tube is disconnected and removed. Valve connectors heretofore known either completely open or completely close a fluid conduit. The open or closed fluid conduit has pneumatic characteristics different from those of the previously connected system components.
  • a controller recognizes a pressure change indicating closure of the valve connector when the removable portion is removed. The controller then begins executing a second predetermined pressure timing sequence to supply pressurized fluid to the remaining portions of the apparatus. If the valve connector is not present or malfunctions when the removable portion is removed, the controller recognizes a pressure change indicating an open fluid line and can execute an error or alarm program sequence (see, for example, the controller described in U.S. Patent Application Serial No. 10/784,323, filed on February 23, 2004 and entitled Compression Treatment System, of which priority is claimed).
  • valve connectors thus disadvantageously requires a more complicated control element in the fluid supply apparatus which must be capable of executing a plurality of pressure/timing sequences in response to acquired pressure measurements.
  • switching between multiple control sequences disadvantageously requires interruption of the system and can require manual input to initiate the second pressure/timing sequence.
  • a fluid conduit connector apparatus that facilitates uninterrupted execution of a single pressure timing sequence when a fluid conduit is removed from a pneumatic system.
  • the fluid conduit connector apparatus overcomes the disadvantages and drawbacks of the prior art when incorporated in a prophylaxis sequential compression apparatus by reducing control system complexity, providing ease of use and minimizing interruption to patients.
  • the fluid conduit connector apparatus includes a port portion including a valve to achieve the advantages of the present disclosure.
  • the fluid conduit connector apparatus has a valve that approximates the pneumatic characteristics of a removed pneumatic system component. The fluid conduit connector apparatus is easily and efficiently fabricated.
  • the fluid conduit connector apparatus in accordance with the principles of the present disclosure, is adapted for use with a compression apparatus.
  • the fluid connector apparatus includes a connector having a plurality of fluid ports formed therewith that facilitates fluid communication between a plurality of fluid conduits of the compression apparatus and a pressurized fluid source.
  • Each of the plurality of fluid ports defines a fluid orifice configured for fluid flow.
  • a valve is disposed with one of the fluid ports. The valve is operable to engage the fluid port such that disconnect of a fluid conduit of the compression apparatus corresponding to the fluid port from the connector reduces a dimension of the fluid orifice of the fluid port.
  • the fluid connector apparatus can include a first connector having a first plurality of fluid ports formed therewith that fluidly communicates with a first plurality of fluid conduits.
  • the first plurality of fluid conduits is a set of three air tubes.
  • a valve is supported with the first connector and is movable such that upon disconnection of one of the first plurality of fluid conduits from the first connector, the valve engages a corresponding fluid port in a configuration that creates a reduced fluid orifice therein.
  • the valve is adapted to approximate pneumatic characteristics of a connected apparatus when the connected apparatus is disconnected from the first connector.
  • one of the fluid ports includes a coupling port and one of the first plurality fluid conduits includes a quick-disconnect fitting adapted for removable mating with the coupling port.
  • the valve is disposed in the coupling port and can, for example, include a spring loaded plunger.
  • An illustrative coupling fitting includes an engagement portion extending therefrom. The spring loaded plunger is displaced by the engagement portion when the coupling fitting is mated to the coupling port.
  • the coupling port includes a cap portion disposed therein.
  • the spring loaded plunger engages the cap portion to create an orifice that provides a pneumatic behavior approximating one of the first plurality of fluid conduits when the coupling fitting is disconnected from the coupling port.
  • the fluid connector apparatus also includes a second connector in fluid communication with a second plurality of fluid conduits.
  • the second plurality of fluid conduits is a set of three air tubes.
  • a plurality of couplings is in fluid communication with the air tubes.
  • the first connector includes a sleeve defining a cavity adapted for mating with the plurality of couplings.
  • the cavity defines a female mating receptacle.
  • the plurality of couplings defines a male mating plug adapted for mating with the female mating receptacle.
  • the first and/or second connectors include improved streamlining of their outer surfaces to prevent snagging of the connectors on patient garments and bedding.
  • the first connector includes an interference key in the cavity to prevent the first connector from mating with legacy connector components.
  • the second connector includes a clearance space for the interference key.
  • the first plurality of fluid conduits is a set of webbed tubing having increased webbing volume between at least one pair of adjacent conduits. At least one interference rib is formed between at least one pair of adjacent fluid ports in the first plurality of fluid ports. The increased webbing volume is aligned with the interference rib if the plurality of fluid conduits is improperly oriented with said first connector. The interference rib thereby prevents attachment of improperly oriented fluid conduits to the first connector.
  • the second plurality of fluid conduits can include an increased webbing volume configured to interfere with an interference rib between adjacent ports in the second connector to prevent attachment of improperly oriented fluid conduits to the second connector.
  • the fluid conduit connector apparatus further includes a gasket disposed in the cavity.
  • the gasket is adapted to provide fluid sealing between the first and second connectors when the first and second connectors are mated together.
  • the sleeve includes a window extending at least partially therethrough.
  • the second connector includes a locking ann extending therefrom.
  • the locking arm is adapted to engage the window to releasably retain the first connector with the second connector.
  • the sleeve can include a slot extending to the window which partially bifurcates the sleeve to define opposing snap arms for engaging the locking arm.
  • One of the first or second connectors can include an alignment slot and the other of the first or second connectors can include an alignment rib configured for engaging the alignment slot.
  • the locking arm includes a leading surface inclined at a first angle to provide a predetermined engagement force between the locking arm and snap arms, and a trailing surface inclined at a second angle to provide a predetermined disengagement force between the locking arm and snap arms.
  • the predetermined engagement force can be designed, for example, to be less than the predetermined disengagement force.
  • a fluid connector apparatus in another embodiment, includes a first connector having tubular walls defining a plurality of fluid ports adapted to connect to a first plurality of fluid conduits. At least one of the fluid ports comprises a coupling port. At least one of the first plurality of fluid conduits includes a coupling fitting adapted for removable mating with the coupling port. A valve is disposed within the coupling port. The valve engages the coupling port to create an orifice approximating pneumatic behavior of one of the first plurality of conduits when the coupling fitting is disconnected from said coupling port.
  • a second connector is adapted to connect to a second plurality of fluid conduits and mate with the first connector.
  • the valve includes a spring loaded plunger disposed in the coupling port.
  • the coupling fitting includes an engagement portion extending therefrom.
  • the spring loaded plunger is displaced by the engagement portion when the coupling fitting is mated to said coupling port.
  • the coupling port includes a cap portion disposed therein. The spring loaded plunger engages the cap portion to create an orifice that provides a pneumatic behavior approximating said one of the first plurality of fluid conduits when the coupling fitting is disconnected from the coupling port.
  • the second connector comprises a plurality of couplings in fluid communication with the second plurality of fluid conduits.
  • the first connector includes a sleeve formed therewith defining a cavity adapted for mating with the plurality of couplings.
  • the sleeve includes a window extending at least partially therethrough.
  • the second connector includes a locking arm extending therefrom which is adapted to engage the window to releasably retain the first connector with the second connector.
  • the sleeve includes a slot extending to the window and partially bifurcating the sleeve to define opposing snap arms for engaging the locking arm.
  • a fluid connector apparatus includes a sleeve connector having tubular walls defining a plurality of fluid ports adapted to connect to a first tubing set including an ankle tube, a calf tube and a thigh tube.
  • One of the ports includes a coupling port.
  • the thigh tube has a coupling fitting adapted for removable mating with the coupling port.
  • a valve is disposed within the coupling port.
  • the valve includes a spring loaded plunger which engages the coupling port to create an orifice approximating pneumatic behavior of the thigh tube when the fitting is disconnected from the coupling port.
  • the coupling fitting includes an engagement portion extending therefrom. The spring loaded plunger is displaced by the engagement portion when the coupling fitting is mated to the coupling port.
  • the coupling port includes a cap portion disposed therein. The spring loaded plunger engages the cap portion to create an orifice that provides pneumatic behavior approximating the thigh tube when the coupling fitting is disconnected from the coupling port.
  • a tubing set connector can be adapted to connect to a second tubing set and mate with the sleeve connector.
  • the tubing set connector includes a plurality of couplings in fluid communication with the second tubing set.
  • the sleeve connector includes a sleeve formed therewith defining a cavity adapted for mating with the plurality of couplings, and having a gasket disposed in the cavity.
  • the gasket is adapted to provide fluid sealing between the sleeve connector and the tubing set connector.
  • the gasket includes a retention portion extending therefrom.
  • the sleeve includes a gasket retention groove adapted to accept the retention portion and thereby retain the gasket to the sleeve.
  • the sleeve includes a window extending at least partially therethrough.
  • the tubing set connector includes a locking arm extending therefrom.
  • the locking arm is adapted to engage the window to releasably retain the sleeve connector with the tubing set connector.
  • the sleeve includes a slot extending to the window and partially bifurcating the sleeve to define opposing snap arms for engaging the locking arm.
  • One of the sleeve connector or the tubing set connector includes an alignment slot and the other of the sleeve connector or the tubing set connector includes an alignment rib configured for engaging the alignment slot.
  • the present application discloses a coupling apparatus including a coupling fitting permanently mounted to a first end of a fluid conduit. A second end of the fluid conduit is connected to an inflatable device. A coupling port is adapted for mating with the coupling fitting and includes a valve supported with the coupling port. The valve approximates pneumatic characteristics of the inflatable device and fluid conduit when the coupling fitting is disconnected from the coupling port.
  • the coupling fitting can include a proximal cylinder and a distal cylinder extending therefrom.
  • a central longitudinal axis extends through the proximal cylinder and distal cylinder.
  • the proximal cylinder has an inside diameter approximately equal to the outside diameter of said fluid conduit to facilitate an interference fit therebetween.
  • the distal cylinder has an inside diameter approximately equal to the outside diameter of said coupling port to facilitate a slip fit therebetween and includes a locking tab extending radially from the outer surface of the distal cylinder.
  • the coupling port includes a fluid communication channel and is incorporated with a sleeve having a detent for engaging the locking tab to removably secure the coupling fitting to the coupling port.
  • the sleeve or interior surface of the first connector can include a detent cavity extending at least partially into the interior surface and adapted for accepting the locking tab.
  • An exemplary detent cavity includes a longitudinal track portion adapted for guiding the locking tab during engagement and disengagement and an annular portion adapted for retaining the locking tab when the coupling fitting is rotated about its longitudinal axis.
  • the detent cavity can have varying depth or width into the interior surface. The varying depth of the detent cavity provides a predetermined engagement/disengagement force/displacement profile between the locking tab and the detent cavity.
  • the locking tab has an outer portion with an enlarged manual engagement surface to assist manipulation of the locking tab.
  • the valve includes a spring loaded plunger.
  • the spring is compressed by engagement between the coupling fitting and the plunger to open the coupling port for fluid communication when the coupling fitting is connected to the coupling port.
  • the spring is extended to force the plunger into the channel.
  • the plunger is perforated to provide a predetermined fluid resistance through the channel when the coupling fitting is disconnected from the coupling port.
  • the present disclosure provides a fluid connector apparatus including a first connector having a first plurality of fluid ports formed therewith which fluidly communicate with a first plurality of fluid conduits.
  • a second connector is in fluid communication with a second plurality of fluid conduits and includes a plurality of couplings in fluid communication therewith.
  • Restrictor means within the first connector are provided for approximating pneumatic characteristics of one of the fluid conduits when it is disconnected from the first connector.
  • the present disclosure provides a method of coupling a pressure source to a pneumatic device.
  • a first plurality of fluid conduits from the pneumatic device is connected to a second plurality of conduits from the pressure source using a multi-port tube connector.
  • One of the first plurality of conduits is disconnected from the multi-port tube connector.
  • a valve is thereby released in the connector which approximates the pneumatic characteristics of one of the first plurality of conduits.
  • the fluid conduit coupling has a coupling fitting with a proximal cylinder and a distal cylinder monolithically formed with the proximal cylinder along a central longitudinal axis.
  • the proximal cylinder has an inside diameter adapted for receiving a fluid conduit.
  • the fluid conduit coupling also includes a fluid port having a male cylindrical portion extending proximally therefrom and a fluid channel extending through the port from the male cylindrical portion to a distal opening.
  • the distal cylinder of the coupling fitting includes a female orifice adapted for mating with the male cylindrical portion of the coupling port.
  • a valve disposed in the port is operatively configured to approximate pneumatic characteristics of a disconnected device when the coupling fitting is detached from the coupling port.
  • the coupling fitting of the fluid conduit coupling has an engagement portion adapted to displace the valve in the coupling port.
  • the valve includes plunger biased proximally by a spring force.
  • the engagement portion is aligned to displace the plunger distally against said spring force when the fitting is attached to the port.
  • the plunger providing an increased fluid passage when displaced distally and a reduced fluid passage when biased proximally.
  • the exemplary embodiments of the fluid conduit connector apparatus and methods of operation disclosed are discussed in terms of prophylaxis compression apparatus and vascular therapy including a prophylaxis compression apparatus for application to a limb of a body and more particularly in terms of a compression apparatus having removable portions. It is envisioned that the present disclosure, however, finds application with a wide variety of pneumatic systems having removable fluid conduits, such as, for example, medical and industrial applications requiring timed sequences of compressed air in a plurality of air tubes.
  • proximal refers to a portion of a structure that is closer to a torso of a subject and the term “distal” refers to a portion that is further from the torso.
  • distal refers to a portion that is further from the torso.
  • subject refers to a patient undergoing vascular therapy using the prophylaxis sequential compression apparatus.
  • the term “practitioner” refers to an individual administering the prophylaxis sequential compression apparatus and may include support personnel.
  • FIGS. 1 and 2 there is illustrated a fluid conduit connector apparatus 10, constructed in accordance with the principals of the present disclosure.
  • the fluid conduit connector apparatus 10 includes a connector having a first connector 12 and second connector 14.
  • First connector 12 is configured for removable engagement with a second connector 14.
  • the first connector 12 includes a first plurality of fluid ports 16 extending proximally therefrom and adapted for receiving a first plurality of fluid conduits 18.
  • Fluid conduits 18 are connected to a compression apparatus, including for example, a compression sleeve (not shown) adapted for disposal and treatment about a limb of a subject (not shown).
  • the second connector 14 includes a second plurality of fluid ports 20 extending distally therefrom and adapted for receiving a second plurality of fluid conduits 22.
  • Fluid conduits 22 fluidly communicate with a pressurized fluid source (not shown) that is adapted to inflate the compression sleeve via the advantageous configuration of fluid conduit connector apparatus 10, as described in accordance with the principles of the present disclosure.
  • conduits 18, 22 may include various tubing such as, for example, non-webbed tubing, etc.
  • connectors 12, 14 facilitate fluid communication between the pressurized fluid source and the compression sleeve.
  • the fluid conduit connector apparatus 10 is illustrated as having a set of three fluid ports in each connector for connecting sets of three fluid conduits, it is contemplated that each connector can have any number of fluid ports without departing from the scope of the present disclosure.
  • the first connector 12 includes a sleeve 24 defining a cavity 26 having a distal opening.
  • the cavity 26 houses distal portions of the first plurality of fluid ports 16 which extend distally within the cavity 26.
  • the second connector 14 includes a plurality of fluid couplings 28 extending proximally therefrom.
  • the plurality of fluid couplings 28 is formed by proximal portions of the second plurality of fluid ports 20 for alignment with the distal portions of the first plurality of fluid ports 16.
  • a locking arm 30 extends proximally from the body portion 32 of the second connector 14.
  • a slot 34 in the sleeve 24 of first connector 12 includes a window 36 adapted for removably accepting the locking arm 30 to retain the first connector 12 to the second connector 14.
  • At least one of the first plurality of ports is a coupling port 38 adapted for receiving a coupling fitting 40.
  • the coupling fitting 40 is permanently attached to the distal end of a corresponding one of the first plurality of fluid conduits 18.
  • a locking tab extending radially from the coupling fitting 40 is configured for engaging a detent cavity 44 in the first connector 12, for example in the sleeve 24 as shown in FIG. 1 .
  • a streamlined outer surface 25 prevents the connectors from snagging on patient clothing or bedding.
  • FIGS. 3 - 7 the various components of the fluid conduit connector apparatus will be described in further detail.
  • a gasket 46 conforms to the space between the plurality of couplings 28 and the distal portion of the first plurality of fluid ports 16 within the cavity 26 when the first connnector 12 is engaged with the second connector 14.
  • the gasket 46 provides sealing for pressurized fluid communication between corresponding fluid conduits by providing a sealed fluid channel including the first plurality of fluid ports and second plurality of fluid ports. It is envisioned that the gasket 46 can be efficiently and inexpensively manufactured using a variety of common materials or fabrication methods, for example by injection molding an elastomeric material or dye cutting a cork or paper based gasket material. It is envisioned that the gasket 46 can be configured for retention to one or the other of the first connector 12 and second connector 14.
  • the gasket includes a proximal lip 48 configured to engage the distal portion of each of the first plurality of fluid ports to provide fluid sealing between the first connector 12 and the second connector 14.
  • the gasket includes a retention portion extending therefrom.
  • the sleeve 24 includes a gasket retention groove adapted to accept the retention portion and thereby retain the gasket to the sleeve 24 when the second connector 14 is removed therefrom.
  • the slot 34 at least partially bifurcates the sleeve 24 to allow spreading of the sleeve 24 under stress when the locking arm 30 is pressed into the slot 34 at its distal end as the first connector 12 is mated to the second connector 14.
  • an engagement portion 49 of the locking arm 30 reaches the window portion 36 of the slot 34 the sleeve returns to its relaxed shape to releasably retain the second connector 14 by its locking arms 30.
  • the locking arm 30 is formed with a leading surface 39 inclined at an angle (i.e., first angle) and a trailing surface 41 inclined at a second angle.
  • the leading surface 39 is inclined at a shallower angle than the trailing 41 surface so that the force to connect the first connector 12 to the second connector 14 is lighter than the force to disconnect the first connector 12 from the second connector 14.
  • Predetermined connection/disconnection forces can thereby be achieved by proper selection of the first and second angle when designing a particular locking arm 30.
  • first connector 12 includes a locking arm 234 that is configured for mating engagement with corresponding slot 230 formed in second connector 14, similar to the arm and slot structure described.
  • An alignment rib 59 ( FIG. 1 ) extends radially from at least one of the plurality of couplings 28 along its longitudinal axis.
  • a corresponding alignment slot (not shown) is provided in the inner surface of the sleeve 24 extending to the distal end thereof for accepting the alignment rib 59. It is contemplated that virtually any type of alignment rib/slot configuration commonly used in the art of for alignment of mating connectors can be used without departing from the scope of the present disclosure.
  • the coupling fitting 40 includes a proximal cylinder 52 and a distal cylinder 54 aligned along a longitudinal axis 56.
  • the proximal cylinder 52 includes a proximal opening 58 and an inside diameter 60 defining an inner surface 62 configured for a press fit corresponding to the outside diameter of one of the first plurality of fluid conduits 18.
  • the corresponding fluid conduit is an air tube which is press fit into the proximal cylinder 52 through its proximal opening 58.
  • the fluid conduit is substantially permanently attached to the proximal cylinder 52 by friction.
  • a variety of suitable adhesives may be applied to the inner surface 62 of the proximal cylinder 52 to permanently attach the fluid conduit and provide a fluid tight seal therebetween.
  • a silicon adhesive, rubber cement, a material specific adhesive compound, an o-ring, a gasket or the like can be used according to methods well known in the art to attach the fluid conduit to the coupling fitting.
  • the distal cylinder 54 comprises an inner surface defined by an inside contour 64 revolved about the longitudinal axis 56 and an outer surface 66 defined by an outside diameter.
  • the inside contour 64 includes a sealing portion 68, a flexing portion 70 and an annular lip portion 72.
  • the sealing portion 68 has an inside diameter adapted for a tight fit against the outside surface of the coupling port 38 to provide at least partial fluid sealing therebetween.
  • the annular lip portion 72 defines an annular ring that compresses against the outside surface of coupling port 38 and provides fluid sealing therebetween.
  • the flexing portion 70 is defined by a reduced wall thickness which allows the distal cylinder 54 to deflect inwardly to facilitate engagement of the locking tab 42 to the detent cavity 44.
  • the sleeve 24 or interior surface of the first connector 12 can include a detent cavity 44 extending at least partially into the interior surface and adapted for accepting the locking tab 42 of the coupling fitting 40.
  • a detent 57 of tab 42 is inserted into sleeve 24 to become disposed in cavity 44. Detent 57 is rotated through cavity 44, via manipulation of fitting 40 and retained in position by bump formed in the wall of cavity 44.
  • the detent cavity shown in FIG. 10 includes a longitudinal track portion 55 (shown in phantom) adapted for guiding the locking tab 42 ( FIG. 9 ) during engagement and disengagement and an annular portion 57 adapted for retaining the locking tab 42 ( FIG.
  • the detent cavity 44 can have varying depth or width into the interior surface.
  • the varying depth of the detent cavity 44 provides a predetermined engagement/disengagement force/displacement profile between the locking tab 42 and the detent cavity.
  • the locking tab has an outer portion with an enlarged manual engagement surface 43 to assist manipulation of the locking tab 42.
  • the coupling fitting includes an engagement portion 74 adapted for opening a valve 76 disposed within the coupling port 38.
  • the engagement portion 74 extends distally from a transverse wall 78 within the coupling fitting 40 to displace a plunger 80 in the valve 76.
  • the transverse wall 78 is disposed within the coupling fitting 40 about between the proximal cylinder 52 and the distal cylinder 54 and orthogonal to the longitudinal axis 56. At least one fluid passageway extends through the transverse wall.
  • valve engagement structure can be used to displace a valve plunger 80 within the scope of the present disclosure.
  • a flat surface of the transverse wall 78 or a rib extending from the inner surface of the distal cylinder 54 can be aligned with a complementary structure within a valve 76 to displace a valve plunger 80 when the coupling fitting 40 is engaged with the coupling port 38.
  • the illustrative embodiment includes a valve 76 disposed within the coupling port 38.
  • the valve 76 includes a plunger 80 movable along the longitudinal axis of the coupling port 38 and biased proximally by a spring 82.
  • the spring 82 is supported by the gasket 46 which is held in place in cavity 26 by protrusion 51 on the gasket 46. Adhesive may alternatively be used to maintain gasket 46 in position.
  • the gasket 46 includes a spring seat formed along the longitudinal axis of any gasket passageway to be aligned with a coupling port. ( FIGS. 4 -5 )
  • the spring seat in the illustrative embodiment includes a central stub 84 supported by radial spars 86 within the gasket opening.
  • the valve can be easily assembled by installing the spring 82 over the distal end of the plunger 80 to form a plunger and spring sub-assembly.
  • the plunger 80 includes a step 88 to engage the proximal end of the spring 82.
  • the plunger and spring sub-assembly can then be installed into the coupling port 38 from its proximal end.
  • the gasket 46 can then be installed into the cavity 26.
  • the plunger and spring sub-assembly can be installed to the gasket 46 by fitting the spring 82 to the spring seat before installing the gasket 46 spring 82 and plunger 80 together to the first connector 12.
  • FIGS. 7 and 8 provide two illustrative embodiments of a plunger 80 according to the present disclosure.
  • the present disclosure illustrates the use of a coil spring 82 to bias the plunger 80
  • spring force could be applied to the plunger 80 by forming a plastic cantilever spring arm that could be formed within the first connector 12.
  • a structure similar to the spring seat could be formed of elastomeric material as part of the gasket 46 to provide a biasing force to the plunger 80 without departing from the scope of the present disclosure.
  • the engagement portion 74 of the coupling fitting forces the plunger 80 to move distally against the force of the spring 82 which is thereby compressed.
  • An open fluid connection is thereby provided from the fluid conduit connected to the coupling fitting 40, through the coupling port 38 to the corresponding one of the second plurality of fluid conduits 22, i.e., the corresponding air tube.
  • a portion of the compression sleeve that fluidly communicates with the pressurized fluid source via coupling port 38 may be removed from the remainder of the compression sleeve.
  • the remaining portion of the compression sleeve continues to provide treatment to the limb of the subject.
  • the coupling fitting 40 is disconnected and not engaged to the coupling port 38.
  • Spring 82 forces the plunger 80 to its proximal limit of travel where the plunger 80 engages a proximal stop such that valve 76 is in a closed position.
  • the plunger 80 is configured to cooperate with an internal structure in the coupling port 38 to define a reduced fluid orifice when the plunger 80 is displaced to its proximal limit.
  • the reduced fluid orifice is designed to provide pneumatic characteristics approximating the pneumatic characteristics of a detached device.
  • a cap 90 having a fluid passageway 92 therethrough is disposed in the proximal opening of the coupling port 38.
  • the cap 90 provides a stop defining a proximal limit of plunger travel and is configured to cooperate with the plunger 80 of valve 76, such that valve 76 reduces the dimension of the fluid orifice of coupling port 38.
  • coupling fitting 40 is connected to the coupling port 38 to force plunger 80 distally and open the fluid connection ( FIG. 6A ), described above, for inflating a removable portion of an inflatable compression sleeve (not shown).
  • a valve seat 282 of plunger 80 is disposed via spring 82 (not shown in FIGS. 6A and 6B for clarity), out of engagement with a conical seat 284 of cap 90. This configuration allows air to flow around the conical seat 284 and through conduit 22 (not shown), and out to the inflatable removable portion of the compression sleeve, as shown by arrows A.
  • coupling fitting 40 For removal of the removable portion of the compression sleeve, coupling fitting 40 is removed from coupling port 38.
  • Spring 82 forces valve seat 282 into engagement with a counter bore edge of conical seat 284.
  • this configuration advantageously reduces the dimension of the fluid orifice of coupling port 38 such that air only flows through cavities defined by semi-circular slots 286 of valve seat 282 and the bore edge of conical seat 284. Slots 286 are formed on the sides of valve seat 282.
  • the cavities defined by slots 286 and conical seat 284 facilitate fluid flow that approximates the pneumatic behavior of the removable portion of the compression sleeve when coupling fitting 40 is connected to coupling port 38 during an open fluid connection.
  • the cavities defined by slots 286 and conical seat 284 may have various configurations and dimensions including geometries such as, for example, elliptical, polygonal, etc.
  • the fluid orifice of coupling port 38 may be variously configured such that corresponding engagement with plunger 80 reduces the orifice dimension to approximate fluid flow through coupling port 38 that would otherwise occur with valve 76 in the open position. It is further contemplated that plunger 80 may includes openings to approximate fluid flow. It is envisioned that valve 76 is operable to reduce the dimension of the fluid orifice of coupling port 38 over a range of closed positions, including partial fluid flow, leakage, etc. to approximate fluid in the port or alternatively, the orifice may completely close to prevent fluid flow through the corresponding port. In a completely closed configuration, pump speed or other settings may be adjusted.
  • the present disclosure provides an air tubing connector for use with a compression apparatus having removable portions, see, for example, the compression sleeve described in U.S. Patent Application Serial No. 10/784,607, filed on February 23, 2004 and entitled Compression Apparatus.
  • Three separate air tube are connected to an ankle portion, a calf portion and a knee portion of the apparatus. Each portion is supplied with a timed sequence of compressed air through its respective air tube.
  • the proximal end of each of the three air tubes is connected to the first plurality of fluid ports 16 in a first connector 12 according to the present disclosure.
  • a mating set of three air tubes extends from a timed pressure source and is connected to the second plurality of fluid ports 20 in a second connector 14 according to the present disclosure.
  • the distal end of the thigh tube is connected to the first connector 12 via a coupling fitting 40 and port 38 as described hereinbefore.
  • the thigh portion can be removed and the tubing attached thereto can be disconnected from the first connector at the coupling port 38.
  • Operation of the valve 76 in the coupling port 38 provides a reduced fluid orifice that restricts airflow therethrough to approximate the pneumatic characteristics of the thigh portion and its corresponding air tube.
  • sensors in the timed pressure source will not detect a change in fluid pressure or flow rate when the thigh portion is removed. This allows the timed pressure source to continue supplying uninterrupted timed air pressure to the ankle and calf portions of the prophylaxis compression apparatus.
  • the first plurality of fluid conduits 18 is a set of webbed tubing 98 having increased webbing volume 100 between at least one pair of adjacent conduits.
  • At least one interference rib 94 is formed between at least one pair of adjacent fluid ports in the first plurality of fluid ports.
  • the increased webbing volume 100 is aligned with the interference rib 94 if the set of webbed tubing 98 is improperly oriented with the first connector 12.
  • the interference rib 94 thereby prevents attachment of improperly oriented fluid conduits to the first connector 12.
  • the second plurality of fluid conduits 22 can include an increased webbing volume configured to interfere with an interference rib between adjacent ports in the second connector 14 to prevent attachment of improperly oriented fluid conduits to the second connector 14.
  • one embodiment includes a first connector 12 having an interference key 96 in the cavity 26 to prevent the first connector 12 from mating with legacy connector components.
  • the second connector 14 includes a clearance space for the interference key 96.
  • FIG. 14 schematically depicts the function of an interference key 96 to prevent connection of certain embodiments of a first connector 12 to certain embodiments of a second connector 13.
  • key slot 98 in second connector 13B provides clearance for interference key 96 in first connector 12B to facilitate mating one to the other.
  • Second connector 13B can also be mated to certain first connectors such as 12A which do not include an interference key.
  • Second connector 13A does not include a key slot and therefore can not be mated with first connector 12B.
  • second connector 13A is a legacy connector.
  • the interference key 96 in a non-compatible connector such as first connector 12B is used to prevent connection of the non-compatible connector to the legacy connector.
  • the connector of the present disclosure may be used with various single and plural bladder compression sleeve devices including, for example, the compression sleeve described in U.S. Patent Application Serial No. 10/784,604, filed on February 23, 2004 and entitled Compression Apparatus. Therefore, the above description should not be construed as limiting, but merely as exemplification of the various embodiments. Those skilled in the art will envision other modifications as long as they are within the scope of the claims appended hereto.

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  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rehabilitation Therapy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Massaging Devices (AREA)
  • Surgical Instruments (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Electron Tubes For Measurement (AREA)
  • Nonmetallic Welding Materials (AREA)
  • Finger-Pressure Massage (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Polarising Elements (AREA)
  • Loading And Unloading Of Fuel Tanks Or Ships (AREA)
  • Non-Positive Displacement Air Blowers (AREA)
  • Prostheses (AREA)
  • Quick-Acting Or Multi-Walled Pipe Joints (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Tea And Coffee (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fluid-Pressure Circuits (AREA)
  • Accessory Devices And Overall Control Thereof (AREA)
EP05713934A 2004-02-23 2005-02-23 Fluid conduit connector apparatus Expired - Lifetime EP1718894B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10/784,639 US7490620B2 (en) 2004-02-23 2004-02-23 Fluid conduit connector apparatus
US10/784,607 US7871387B2 (en) 2004-02-23 2004-02-23 Compression sleeve convertible in length
US10/784,604 US7282038B2 (en) 2004-02-23 2004-02-23 Compression apparatus
US10/784,323 US7354410B2 (en) 2004-02-23 2004-02-23 Compression treatment system
PCT/US2005/005599 WO2005083313A1 (en) 2004-02-23 2005-02-23 Fluid conduit connector apparatus

Publications (2)

Publication Number Publication Date
EP1718894A1 EP1718894A1 (en) 2006-11-08
EP1718894B1 true EP1718894B1 (en) 2010-07-07

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ID=34916527

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Application Number Title Priority Date Filing Date
EP10185262.2A Withdrawn EP2319476A3 (en) 2004-02-23 2005-02-23 Compression treatment system
EP10185260.6A Expired - Lifetime EP2314268B1 (en) 2004-02-23 2005-02-23 Compression treatment system
EP05713933.9A Expired - Lifetime EP1722738B1 (en) 2004-02-23 2005-02-23 Compression treatment system
EP05713935A Expired - Lifetime EP1720504B1 (en) 2004-02-23 2005-02-23 Compression apparatus
EP05723526A Expired - Lifetime EP1720505B1 (en) 2004-02-23 2005-02-23 Compression apparatus
EP05713934A Expired - Lifetime EP1718894B1 (en) 2004-02-23 2005-02-23 Fluid conduit connector apparatus

Family Applications Before (5)

Application Number Title Priority Date Filing Date
EP10185262.2A Withdrawn EP2319476A3 (en) 2004-02-23 2005-02-23 Compression treatment system
EP10185260.6A Expired - Lifetime EP2314268B1 (en) 2004-02-23 2005-02-23 Compression treatment system
EP05713933.9A Expired - Lifetime EP1722738B1 (en) 2004-02-23 2005-02-23 Compression treatment system
EP05713935A Expired - Lifetime EP1720504B1 (en) 2004-02-23 2005-02-23 Compression apparatus
EP05723526A Expired - Lifetime EP1720505B1 (en) 2004-02-23 2005-02-23 Compression apparatus

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EP (6) EP2319476A3 (ko)
JP (4) JP4571156B2 (ko)
KR (5) KR100868148B1 (ko)
CN (1) CN102614074B (ko)
AT (3) ATE473390T1 (ko)
AU (4) AU2005216934B2 (ko)
CA (4) CA2552353C (ko)
DE (2) DE602005021460D1 (ko)
DK (1) DK1720504T3 (ko)
ES (4) ES2414880T3 (ko)
HK (1) HK1091390A1 (ko)
IL (4) IL176409A (ko)
NO (4) NO20064256L (ko)
PL (2) PL1720505T3 (ko)
WO (4) WO2005082316A2 (ko)

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FR2789811B1 (fr) 1999-02-11 2001-05-18 Radiall Sa Raccord coaxial pour relier deux cartes de circuit imprime
US6290662B1 (en) 1999-05-28 2001-09-18 John K. Morris Portable, self-contained apparatus for deep vein thrombosis (DVT) prophylaxis
US6592534B1 (en) * 1999-12-27 2003-07-15 Aircast, Inc. Inflatable medical appliance for prevention of DVT
JP2001286521A (ja) * 2000-04-10 2001-10-16 Nippon Colin Co Ltd 静脈血栓塞栓症防止装置
US6558338B1 (en) * 2000-11-20 2003-05-06 Mego Afek Industrial Measuring Instruments System for and method of applying pressure to human body
JP3951637B2 (ja) * 2001-06-14 2007-08-01 松下電工株式会社 エアーマッサージ機
JP2003319988A (ja) * 2002-05-07 2003-11-11 Marutaka Co Ltd 腕用エアマッサージ機
JP2005533981A (ja) 2002-07-27 2005-11-10 ジェイダブリュエル・マスキン−オージー・プラストファブリック・エイ／エス 高速カップリング装置およびカップリング・ソケットを組み立てる方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11865034B2 (en) 2015-01-27 2024-01-09 Medivance Incorporated Medical pad and system for thermotherapy
US12193968B2 (en) 2015-01-27 2025-01-14 Medivance Incorporated Medical pad and system for thermotherapy
US12241570B2 (en) 2021-07-07 2025-03-04 C. R. Bard, Inc. Negative pressure connector seal

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JP2007522892A (ja) 2007-08-16
EP1722738A1 (en) 2006-11-22
JP2007522890A (ja) 2007-08-16
KR100918718B1 (ko) 2009-09-24
AU2005217424A1 (en) 2005-09-09
EP1720505A2 (en) 2006-11-15
JP4571156B2 (ja) 2010-10-27
PL1720504T3 (pl) 2010-11-30
AU2005216924B2 (en) 2009-03-12
WO2005082315A1 (en) 2005-09-09
CN102614074B (zh) 2015-09-23
ATE468834T1 (de) 2010-06-15
WO2005082316A2 (en) 2005-09-09
NO20064255L (no) 2006-09-20
JP4686485B2 (ja) 2011-05-25
AU2005216934A1 (en) 2005-09-09
ES2806930T3 (es) 2021-02-19
KR100914569B1 (ko) 2009-08-31
KR20060133587A (ko) 2006-12-26
EP1720505B1 (en) 2011-12-14
IL176410A0 (en) 2006-10-05
IL176410A (en) 2010-06-16
KR20070007085A (ko) 2007-01-12
ES2346546T3 (es) 2010-10-18
CA2552353A1 (en) 2005-09-09
KR20080091404A (ko) 2008-10-10
CN102614074A (zh) 2012-08-01
KR100873540B1 (ko) 2008-12-11
EP1718894A1 (en) 2006-11-08
JP2007522891A (ja) 2007-08-16
EP2314268A3 (en) 2014-06-18
AU2005216934B2 (en) 2007-12-13
EP2319476A3 (en) 2014-10-01
WO2005083313A1 (en) 2005-09-09
KR20070027506A (ko) 2007-03-09
KR100868148B1 (ko) 2008-11-12
DK1720504T3 (da) 2010-08-23
EP2314268B1 (en) 2020-04-22
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ES2378886T3 (es) 2012-04-18
NO20064281L (no) 2006-09-21
ATE473390T1 (de) 2010-07-15
EP2314268A2 (en) 2011-04-27
PL1720505T3 (pl) 2012-05-31
CA2552354C (en) 2010-07-06
JP2007522889A (ja) 2007-08-16
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HK1091390A1 (en) 2007-01-19
JP4602996B2 (ja) 2010-12-22
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NO20064256L (no) 2006-09-20
CA2552331C (en) 2009-04-28

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