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EP0763103A4 - GENE DELIVERING VECTOR FROM PLASMID DNA PACKED IN ADENVIRUS AND A PACKING CELL LINE - Google Patents

GENE DELIVERING VECTOR FROM PLASMID DNA PACKED IN ADENVIRUS AND A PACKING CELL LINE

Info

Publication number
EP0763103A4
EP0763103A4 EP95917176A EP95917176A EP0763103A4 EP 0763103 A4 EP0763103 A4 EP 0763103A4 EP 95917176 A EP95917176 A EP 95917176A EP 95917176 A EP95917176 A EP 95917176A EP 0763103 A4 EP0763103 A4 EP 0763103A4
Authority
EP
European Patent Office
Prior art keywords
adenvirus
cell line
plasmid dna
packing cell
delivering vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95917176A
Other languages
German (de)
French (fr)
Other versions
EP0763103A1 (en
Inventor
Gary J Nabel
Michael J Imperiale
Takeshi Ohno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan Ann Arbor
Original Assignee
University of Michigan Ann Arbor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan Ann Arbor filed Critical University of Michigan Ann Arbor
Publication of EP0763103A1 publication Critical patent/EP0763103A1/en
Publication of EP0763103A4 publication Critical patent/EP0763103A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP95917176A 1994-04-28 1995-04-25 GENE DELIVERING VECTOR FROM PLASMID DNA PACKED IN ADENVIRUS AND A PACKING CELL LINE Withdrawn EP0763103A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23499094A 1994-04-28 1994-04-28
US234990 1994-04-28
PCT/US1995/005174 WO1995029993A1 (en) 1994-04-28 1995-04-25 Gene delivery vector using plasmid dna packaged into an adenovirus and a packaging cell line

Publications (2)

Publication Number Publication Date
EP0763103A1 EP0763103A1 (en) 1997-03-19
EP0763103A4 true EP0763103A4 (en) 1998-07-15

Family

ID=22883604

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95917176A Withdrawn EP0763103A4 (en) 1994-04-28 1995-04-25 GENE DELIVERING VECTOR FROM PLASMID DNA PACKED IN ADENVIRUS AND A PACKING CELL LINE

Country Status (4)

Country Link
EP (1) EP0763103A4 (en)
JP (1) JPH10507061A (en)
CA (1) CA2189067A1 (en)
WO (1) WO1995029993A1 (en)

Families Citing this family (35)

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US20020164782A1 (en) 1999-02-10 2002-11-07 Gregory Richard J. Adenovirus vectors for gene therapy
US5670488A (en) * 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
US7252989B1 (en) 1994-04-04 2007-08-07 Board Of Regents, The University Of Texas System Adenovirus supervector system
DK0787200T3 (en) * 1994-10-28 2005-08-15 Univ Pennsylvania Improved adenovirus and methods for its use
AU5551996A (en) * 1995-04-17 1996-11-07 Board Of Regents, The University Of Texas System An adenovirus helper-virus system
EP0888086B1 (en) 1996-02-15 2005-07-27 Biosense Webster, Inc. Excavation probe
WO1997032481A1 (en) * 1996-03-07 1997-09-12 The Regents Of The University Of California Helper-free, totally defective adenovirus for gene therapy
US6443974B1 (en) 1996-07-28 2002-09-03 Biosense, Inc. Electromagnetic cardiac biostimulation
US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
DE69841807D1 (en) 1997-11-06 2010-09-16 Novartis Vaccines & Diagnostic NEISSERIAL ANTIGENE
AU1539399A (en) * 1997-11-25 1999-06-15 Medical University Of South Carolina Inhibitors of nitric oxide synthase
WO1999032647A1 (en) * 1997-12-23 1999-07-01 Introgene B.V. Adeno-associated virus and adenovirus chimeric recombinant viruses useful for the integration of foreign genetic information into the chromosomal dna of target cells
CN1224708C (en) 1998-01-14 2005-10-26 启龙股份公司 i (Neisseria meningitidis) antigens
DE69838526T2 (en) 1998-02-05 2008-07-03 Biosense Webster, Inc., Diamond Bar Device for releasing a drug in the heart
MX343744B (en) 1998-05-01 2016-11-22 J Craig Venter Inst Inc Neisseria meningitidis antigens and compositions.
US6113913A (en) * 1998-06-26 2000-09-05 Genvec, Inc. Recombinant adenovirus
GB9817660D0 (en) * 1998-08-13 1998-10-07 Angeletti P Ist Richerche Bio Adenoviral vectors encoding erythropoietin and their use in gene therapy
EP2278007B1 (en) 1999-04-30 2014-04-16 Novartis Vaccines and Diagnostics S.r.l. Conserved neisserial antigens
GB9911683D0 (en) 1999-05-19 1999-07-21 Chiron Spa Antigenic peptides
GB9916529D0 (en) 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
ES2564463T3 (en) 1999-10-29 2016-03-22 Glaxosmithkline Biologicals S.A. Neisserial antigenic peptides
CA2397508C (en) 2000-01-17 2015-11-24 Chiron Spa Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins
NZ583028A (en) 2000-10-27 2011-10-28 Novartis Vaccines & Diagnostic Nucleic acids and proteins from streptococcus groups A & B
GB0107661D0 (en) 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
GB0107658D0 (en) 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
ES2312649T3 (en) 2001-12-12 2009-03-01 Novartis Vaccines And Diagnostics S.R.L. IMMUNIZATION AGAINST CHLAMYDIA TRACHOMATIS.
GB0308198D0 (en) 2003-04-09 2003-05-14 Chiron Srl ADP-ribosylating bacterial toxin
JP4792390B2 (en) 2004-03-29 2011-10-12 株式会社ガルファーマ Novel galectin-9 variant protein and use thereof
DK1804835T3 (en) 2004-09-13 2010-10-11 Genzyme Corp Multimeric constructions
AR059089A1 (en) 2006-01-20 2008-03-12 Genzyme Corp INTRAVENTRICULAR ADMINISTRATION OF AN ENZYME FOR LISOSOMAL STORAGE DISEASES
JP2009526066A (en) 2006-02-09 2009-07-16 ジェンザイム・コーポレーション Slow intraventricular delivery
WO2009030978A2 (en) 2006-06-09 2009-03-12 Novartis Ag Conformers of bacterial adhesins
EP2812012A1 (en) 2012-02-07 2014-12-17 Global Bio Therapeutics USA, Inc. Compartmentalized method of nucleic acid delivery and compositions and uses thereof
MX378673B (en) 2013-08-08 2025-03-10 Global Bio Therapeutics Inc Clamping device for minimally invasive procedures and its uses.
EP4340855A1 (en) 2021-08-13 2024-03-27 Triovance Holding LLC A skin substitute composition and methods of producing and using the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994028152A1 (en) * 1993-05-28 1994-12-08 Transgene S.A. Defective adenoviruses and corresponding complementation lines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0648271B1 (en) * 1991-08-20 2003-04-16 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Adenovirus mediated transfer of genes to the gastrointestinal tract
FI951404A7 (en) * 1992-09-25 1995-03-24 Rhone Poulenc Rorer Sa Adenovirus vectors for transferring foreign genes into cells of the central nervous system, especially the brain

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994028152A1 (en) * 1993-05-28 1994-12-08 Transgene S.A. Defective adenoviruses and corresponding complementation lines

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GRABLE AND HEARING: "cis and trans Requirements for the selective packaging of Adenovirus type 5 DNA", JOURNAL OF VIROLOGY, vol. 66, no. 2, February 1992 (1992-02-01), AMERICAN SOCIETY FOR MICROBIOLOGY US, pages 723 - 731, XP002012398 *
MASTRANGELI ET AL.: "Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 91, January 1993 (1993-01-01), pages 225 - 234, XP000616634 *
ROSENFELD ET AL.: "In vivo transfer of the human Cystic Fibrosis Transmembrane Conductance Regulator gene to the airway epithelium", CELL, vol. 68, no. 1, 10 January 1992 (1992-01-10), NA US, pages 143 - 155, XP002064228 *
See also references of WO9529993A1 *
STRATFORD-PERRICAUDET AND PERRICAUDET: "Gene transfer into animals: the promise of adenovirus", HUMAN GENE TRANSFER (COHEN-HAGUENAUER AND BOIRON EDS.), vol. 219, 1991, pages 51 - 61, XP002064227 *

Also Published As

Publication number Publication date
JPH10507061A (en) 1998-07-14
EP0763103A1 (en) 1997-03-19
CA2189067A1 (en) 1995-11-09
WO1995029993A1 (en) 1995-11-09

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