EP0659077A4 - Controlled release pilocarpine delivery system. - Google Patents
Controlled release pilocarpine delivery system.Info
- Publication number
- EP0659077A4 EP0659077A4 EP19930916952 EP93916952A EP0659077A4 EP 0659077 A4 EP0659077 A4 EP 0659077A4 EP 19930916952 EP19930916952 EP 19930916952 EP 93916952 A EP93916952 A EP 93916952A EP 0659077 A4 EP0659077 A4 EP 0659077A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- delivery system
- controlled release
- release pilocarpine
- pilocarpine delivery
- controlled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- QCHFTSOMWOSFHM-WPRPVWTQSA-N (+)-Pilocarpine Chemical compound C1OC(=O)[C@@H](CC)[C@H]1CC1=CN=CN1C QCHFTSOMWOSFHM-WPRPVWTQSA-N 0.000 title 1
- QCHFTSOMWOSFHM-UHFFFAOYSA-N SJ000285536 Natural products C1OC(=O)C(CC)C1CC1=CN=CN1C QCHFTSOMWOSFHM-UHFFFAOYSA-N 0.000 title 1
- 238000013270 controlled release Methods 0.000 title 1
- 229960001416 pilocarpine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US907852 | 1978-05-19 | ||
US07/907,952 US5268231A (en) | 1991-07-02 | 1992-07-02 | Method for the treatment of surfaces |
PCT/US1993/006323 WO1994001108A1 (en) | 1992-07-02 | 1993-07-02 | Controlled release pilocarpine delivery system |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0659077A4 true EP0659077A4 (en) | 1995-03-21 |
EP0659077A1 EP0659077A1 (en) | 1995-06-28 |
Family
ID=25424918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP93916952A Withdrawn EP0659077A1 (en) | 1992-07-02 | 1993-07-02 | Controlled release pilocarpine delivery system |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP0659077A1 (en) |
WO (1) | WO1994001108A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2737661B1 (en) * | 1995-08-08 | 1997-10-31 | Mgi Pharma Inc | PHARMACEUTICAL COMPOSITION IN THE FORM OF TABLETS COMPRISING PILOCARPINE HYDROCHLORIDE |
GB9618341D0 (en) * | 1996-09-03 | 1996-10-16 | Scotia Holdings Plc | Method of treatment |
FR2864901B1 (en) * | 2004-01-09 | 2007-10-05 | Philippe Perovitch | COMPOSITION FOR THE TREATMENT IN CONTACT WITH HYPOSIALIES, INCLUDING PILOCARPINE AND MULTIPLE EFFECTS |
BRPI0912679A2 (en) * | 2008-05-16 | 2016-01-26 | Axis Inc | pharmaceutical composition for the treatment of fibromyalgia |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4209505A (en) * | 1979-04-03 | 1980-06-24 | Mikhail Adib R | Pilocarpine mouthwash for dry mouth relief |
WO1991001130A1 (en) * | 1989-07-14 | 1991-02-07 | Alza Corporation | Oral osmotic device with hydrogel driving member |
WO1992000044A1 (en) * | 1990-06-27 | 1992-01-09 | Insite Vision Incorporated | Ophthalmic suspensions |
WO1992003124A1 (en) * | 1990-08-21 | 1992-03-05 | Oramed, Inc. | Controlled release formulations and method |
-
1993
- 1993-07-02 EP EP93916952A patent/EP0659077A1/en not_active Withdrawn
- 1993-07-02 WO PCT/US1993/006323 patent/WO1994001108A1/en not_active Application Discontinuation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4209505A (en) * | 1979-04-03 | 1980-06-24 | Mikhail Adib R | Pilocarpine mouthwash for dry mouth relief |
WO1991001130A1 (en) * | 1989-07-14 | 1991-02-07 | Alza Corporation | Oral osmotic device with hydrogel driving member |
WO1992000044A1 (en) * | 1990-06-27 | 1992-01-09 | Insite Vision Incorporated | Ophthalmic suspensions |
WO1992003124A1 (en) * | 1990-08-21 | 1992-03-05 | Oramed, Inc. | Controlled release formulations and method |
Non-Patent Citations (5)
Title |
---|
DESHPANDE SG ET AL: "Sustained release ophthalmic formulations of pilocarpine.", J PHARM PHARMACOL (ENGLAND), MAR 1989, VOL. 41, NO. 3, PAGE(S) 197-200, * |
PAVAN-LANGSTON D: "Potential use of ocular-insert therapy in dry eyes.", INT OPHTHALMOL CLIN (UNITED STATES) SPRING, 1973, VOL. 13, NO. 1, PAGE(S) 231-8, * |
SCHULLER DE ET AL: "Treatment of radiation side effects with oral pilocarpine.", J SURG ONCOL (UNITED STATES), DEC 1989, VOL. 42, NO. 4, PAGE(S) 272-6, * |
See also references of WO9401108A1 * |
SEVERIN GA: "Keratoconjunctivitis sicca.", VET CLIN NORTH AM (UNITED STATES), SEP 1973, VOL. 3, NO. 3, PAGE(S) 407-22, * |
Also Published As
Publication number | Publication date |
---|---|
EP0659077A1 (en) | 1995-06-28 |
WO1994001108A1 (en) | 1994-01-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A4 | Supplementary search report drawn up and despatched | ||
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19950105 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 19980224 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20001016 |