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DOP2016000202A - Proteínas de fusión uti - Google Patents

Proteínas de fusión uti

Info

Publication number
DOP2016000202A
DOP2016000202A DO2016000202A DO2016000202A DOP2016000202A DO P2016000202 A DOP2016000202 A DO P2016000202A DO 2016000202 A DO2016000202 A DO 2016000202A DO 2016000202 A DO2016000202 A DO 2016000202A DO P2016000202 A DOP2016000202 A DO P2016000202A
Authority
DO
Dominican Republic
Prior art keywords
fusion proteins
uti fusion
same
uti
produce
Prior art date
Application number
DO2016000202A
Other languages
English (en)
Inventor
Aaron Chamberlain
Qiang Liu
Mathias Schmidt
Original Assignee
Takeda Pharmaceuticals Co
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co, Takeda Gmbh filed Critical Takeda Pharmaceuticals Co
Publication of DOP2016000202A publication Critical patent/DOP2016000202A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • C07K14/8117Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/90Fusion polypeptide containing a motif for post-translational modification
    • C07K2319/91Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA PRESENTE INVENCIÓN PROVEE PROTEÍNAS DE FUSIÓN UTI, SECUENCIAS DE ADN PARA PRODUCIR LAS MISMAS, Y COMPOSICIONES FARMACÉUTICAS Y MÉTODOS PARA USAR LAS MISMAS.
DO2016000202A 2014-02-24 2016-08-10 Proteínas de fusión uti DOP2016000202A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461943617P 2014-02-24 2014-02-24

Publications (1)

Publication Number Publication Date
DOP2016000202A true DOP2016000202A (es) 2016-12-15

Family

ID=52629709

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2016000202A DOP2016000202A (es) 2014-02-24 2016-08-10 Proteínas de fusión uti

Country Status (38)

Country Link
US (4) US9856310B2 (es)
EP (2) EP3443978A1 (es)
JP (4) JP6574431B2 (es)
KR (3) KR102461210B1 (es)
CN (2) CN106232135B (es)
AR (1) AR101597A1 (es)
AU (4) AU2015218704B2 (es)
BR (1) BR112016019390B1 (es)
CA (2) CA3178241A1 (es)
CL (1) CL2016002136A1 (es)
CR (1) CR20160444A (es)
CY (1) CY1120997T1 (es)
DK (1) DK3110434T3 (es)
DO (1) DOP2016000202A (es)
EA (2) EA202091567A1 (es)
EC (1) ECSP16076535A (es)
ES (1) ES2700149T3 (es)
GE (1) GEP20196970B (es)
HR (1) HRP20182029T1 (es)
IL (1) IL247321B (es)
JO (1) JO3729B1 (es)
LT (1) LT3110434T (es)
MA (1) MA39347B2 (es)
MX (4) MX384070B (es)
MY (1) MY178774A (es)
NZ (3) NZ760008A (es)
PE (1) PE20170257A1 (es)
PH (1) PH12016501629B1 (es)
PL (1) PL3110434T3 (es)
PT (1) PT3110434T (es)
RS (1) RS58285B1 (es)
SG (2) SG10201708400QA (es)
SI (1) SI3110434T1 (es)
SM (1) SMT201800674T1 (es)
TW (1) TWI694084B (es)
UA (1) UA118866C2 (es)
WO (1) WO2015127391A1 (es)
ZA (1) ZA201606327B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS58285B1 (sr) * 2014-02-24 2019-03-29 Takeda Gmbh Uti-fuzioni proteini
BR112019025792A2 (pt) * 2017-06-07 2020-07-07 Spark Therapeutics, Inc. agentes de aperfeiçoamento para transfecção de células melhoradas e/ou produção de vetor raav
WO2020106881A1 (en) * 2018-11-20 2020-05-28 Diamedica Inc. Modified ulinastatin polypeptides
JP2021050161A (ja) 2019-09-25 2021-04-01 武田薬品工業株式会社 複素環化合物及びその用途
JP2021080177A (ja) 2019-11-14 2021-05-27 武田薬品工業株式会社 複素環化合物及びその用途
CN115515616A (zh) 2020-03-05 2022-12-23 代阿麦迪卡美国股份有限公司 乌司他丁多肽

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CN101721699B (zh) * 2008-10-13 2012-11-07 成都康弘生物科技有限公司 Vegf受体融合蛋白在制备治疗伴随vegf升高的炎症反应的药物中的应用
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RS58285B1 (sr) * 2014-02-24 2019-03-29 Takeda Gmbh Uti-fuzioni proteini

Also Published As

Publication number Publication date
US20180072795A1 (en) 2018-03-15
KR102722304B1 (ko) 2024-10-28
JP2017512058A (ja) 2017-05-18
US20160362475A1 (en) 2016-12-15
LT3110434T (lt) 2018-12-27
US20220127334A1 (en) 2022-04-28
CR20160444A (es) 2017-04-21
TWI694084B (zh) 2020-05-21
PT3110434T (pt) 2018-12-19
SMT201800674T1 (it) 2019-01-11
AR101597A1 (es) 2016-12-28
CA2939639A1 (en) 2015-08-27
US10351618B2 (en) 2019-07-16
AU2019204448B2 (en) 2021-06-10
SI3110434T1 (sl) 2019-02-28
CA2939639C (en) 2023-01-24
MA39347B2 (fr) 2020-05-29
US9856310B2 (en) 2018-01-02
JP6938565B2 (ja) 2021-09-22
WO2015127391A1 (en) 2015-08-27
CN106232135A (zh) 2016-12-14
PH12016501629A1 (en) 2017-02-06
EP3443978A1 (en) 2019-02-20
DK3110434T3 (en) 2019-01-14
US20200040062A1 (en) 2020-02-06
AU2015218704B2 (en) 2019-05-02
AU2019204448A1 (en) 2019-07-11
IL247321A0 (en) 2016-09-29
EP3110434A1 (en) 2017-01-04
EP3110434B1 (en) 2018-09-19
EA202091567A1 (ru) 2021-07-30
JP2023123763A (ja) 2023-09-05
SG10201708400QA (en) 2017-11-29
KR20240155987A (ko) 2024-10-29
AU2015218704A1 (en) 2016-09-22
AU2023200875A1 (en) 2023-04-27
AU2021225156A1 (en) 2021-09-30
KR102461210B1 (ko) 2022-10-31
MX2019013124A (es) 2020-08-31
NZ724196A (en) 2022-01-28
MX384070B (es) 2025-03-14
MX2016010950A (es) 2017-04-25
CN110092837B (zh) 2024-01-02
PH12016501629B1 (en) 2023-10-20
UA118866C2 (uk) 2019-03-25
KR20220151005A (ko) 2022-11-11
IL247321B (en) 2020-06-30
AU2021225156B2 (en) 2022-11-24
PE20170257A1 (es) 2017-03-30
MX2024000004A (es) 2024-02-20
ZA201606327B (en) 2019-01-30
RS58285B1 (sr) 2019-03-29
NZ760008A (en) 2023-03-31
JP2019187427A (ja) 2019-10-31
GEP20196970B (en) 2019-04-25
HRP20182029T1 (hr) 2019-02-08
MA39347A1 (fr) 2018-06-29
JP6574431B2 (ja) 2019-09-11
CN110092837A (zh) 2019-08-06
PL3110434T3 (pl) 2019-01-31
CL2016002136A1 (es) 2017-08-11
SG11201606691QA (en) 2016-09-29
JP2022002513A (ja) 2022-01-11
NZ760789A (en) 2023-03-31
BR112016019390B1 (pt) 2023-11-14
EA037256B1 (ru) 2021-02-26
CA3178241A1 (en) 2015-08-27
TW201630931A (zh) 2016-09-01
ES2700149T3 (es) 2019-02-14
CN106232135B (zh) 2019-12-10
MY178774A (en) 2020-10-20
BR112016019390A2 (pt) 2017-10-24
JO3729B1 (ar) 2021-01-31
CY1120997T1 (el) 2019-12-11
ECSP16076535A (es) 2017-08-31
EA201691702A1 (ru) 2017-01-30
KR20160141718A (ko) 2016-12-09

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