DE69917051D1 - "flow-zytometrischer" vollblut- dendritzelle- immunfunctiontest - Google Patents
"flow-zytometrischer" vollblut- dendritzelle- immunfunctiontestInfo
- Publication number
- DE69917051D1 DE69917051D1 DE69917051T DE69917051T DE69917051D1 DE 69917051 D1 DE69917051 D1 DE 69917051D1 DE 69917051 T DE69917051 T DE 69917051T DE 69917051 T DE69917051 T DE 69917051T DE 69917051 D1 DE69917051 D1 DE 69917051D1
- Authority
- DE
- Germany
- Prior art keywords
- whole blood
- flow
- immunfunction
- dendritz
- cytometric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5002—Partitioning blood components
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US158406 | 1998-09-22 | ||
US09/158,406 US6495333B1 (en) | 1998-09-22 | 1998-09-22 | Flow cytometric, whole blood dendritic cell immune function assay |
PCT/US1999/021731 WO2000017657A1 (en) | 1998-09-22 | 1999-09-21 | A flow cytometric, whole blood dendritic cell immune function assay |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69917051D1 true DE69917051D1 (de) | 2004-06-09 |
DE69917051T2 DE69917051T2 (de) | 2004-09-02 |
Family
ID=22567963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69917051T Expired - Lifetime DE69917051T2 (de) | 1998-09-22 | 1999-09-21 | "flow-zytometrischer" vollblut- dendritzelle- immunfunctiontest |
Country Status (6)
Country | Link |
---|---|
US (1) | US6495333B1 (de) |
EP (1) | EP1116037B1 (de) |
JP (1) | JP4450998B2 (de) |
AT (1) | ATE266204T1 (de) |
DE (1) | DE69917051T2 (de) |
WO (1) | WO2000017657A1 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2264428B1 (de) | 1997-01-31 | 2017-05-03 | Xy, Llc | Optisches Gerät mit fokussierendem Reflektor zur Konvergenz von Strahlung auf einen Partikelfluss |
US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
US6071689A (en) | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
US7351546B2 (en) * | 1998-09-22 | 2008-04-01 | Becton, Dickinson And Company | Flow cytometric, whole blood dendritic cell immune function assay |
US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
ATE374945T1 (de) * | 2000-09-06 | 2007-10-15 | Ortho Mcneil Pharm Inc | Verfahren zum überwachen des effekts von kathepsin-s-inhibitoren |
US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
AU3768902A (en) | 2000-11-29 | 2002-06-11 | Xy Inc | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
US7563584B2 (en) * | 2001-07-10 | 2009-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for detecting the activation state of multiple proteins in single cells |
US7393656B2 (en) * | 2001-07-10 | 2008-07-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for risk stratification |
US7381535B2 (en) * | 2002-07-10 | 2008-06-03 | The Board Of Trustees Of The Leland Stanford Junior | Methods and compositions for detecting receptor-ligand interactions in single cells |
US7097833B2 (en) | 2002-07-19 | 2006-08-29 | Boston Scientific Scimed, Inc. | Selected cell delivery for heart failure |
US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
CN1674780A (zh) | 2002-08-01 | 2005-09-28 | Xy公司 | 低压精子分离系统 |
CA2534394C (en) | 2002-08-15 | 2013-01-08 | Xy, Inc. | High resolution flow cytometer |
AU2002950778A0 (en) * | 2002-08-15 | 2002-09-12 | The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland | A method of characterizing dendritic cells |
US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
HUE026838T2 (en) | 2003-03-28 | 2016-07-28 | Inguran Llc | Method for providing sex-sorted animal sperm |
US20040197836A1 (en) * | 2003-04-04 | 2004-10-07 | Hashemi Brian B. | Measurement of F-actin in whole blood cellular subsets |
SE0301058D0 (sv) * | 2003-04-10 | 2003-04-10 | Biacore Ab | Method and kit for cell analyte assay |
US20040219612A1 (en) * | 2003-05-02 | 2004-11-04 | Beckman Coulter, Inc. | Methods for detecting intracellular defensins in various leukocyte subpopulations |
US7354773B2 (en) * | 2003-05-14 | 2008-04-08 | Beckman Coulter, Inc. | Method and apparatus for preparing cell samples for intracellular antigen detection using flow cytometry |
NZ544103A (en) | 2003-05-15 | 2010-10-29 | Xy Llc | Efficient haploid cell sorting for flow cytometer systems |
CA2561661C (en) | 2004-03-29 | 2015-11-24 | Monsanto Technology Llc | Sperm suspensions for sorting into x or y chromosome-bearing enriched populations |
AU2005260887B2 (en) * | 2004-07-08 | 2010-07-08 | Medinet Co., Ltd. | Dendritic cell, drug containing the dendritic cell, therapeutic method using the dendritic cell and method of culturing gamma delta T cell |
WO2006012597A2 (en) | 2004-07-22 | 2006-02-02 | Monsanto Technology Llc | Process for enriching a population of sperm cells |
US8214157B2 (en) * | 2006-03-31 | 2012-07-03 | Nodality, Inc. | Method and apparatus for representing multidimensional data |
US8771971B2 (en) * | 2006-07-28 | 2014-07-08 | The Research Foundation Of State University Of New York | Methods and kits for measurement of lymphocyte function |
TWI443063B (zh) * | 2007-07-11 | 2014-07-01 | Mitsubishi Gas Chemical Co | 用於製造過氧化氫之作用溶液的再生觸媒之製造方法 |
WO2009025847A2 (en) | 2007-08-21 | 2009-02-26 | Nodality, Inc. | Methods for diagnosis, prognosis and methods of treatment |
US20090291458A1 (en) * | 2008-05-22 | 2009-11-26 | Nodality, Inc. | Method for Determining the Status of an Individual |
US8399206B2 (en) | 2008-07-10 | 2013-03-19 | Nodality, Inc. | Methods for diagnosis, prognosis and methods of treatment |
US8227202B2 (en) | 2008-07-10 | 2012-07-24 | Nodality, Inc. | Methods for diagnosis, prognosis and methods of treatment |
US9034257B2 (en) | 2008-10-27 | 2015-05-19 | Nodality, Inc. | High throughput flow cytometry system and method |
US8309306B2 (en) * | 2008-11-12 | 2012-11-13 | Nodality, Inc. | Detection composition |
US20100209929A1 (en) * | 2009-01-14 | 2010-08-19 | Nodality, Inc., A Delaware Corporation | Multiple mechanisms for modulation of jak/stat activity |
US20100204973A1 (en) * | 2009-01-15 | 2010-08-12 | Nodality, Inc., A Delaware Corporation | Methods For Diagnosis, Prognosis And Treatment |
US20100233733A1 (en) * | 2009-02-10 | 2010-09-16 | Nodality, Inc., A Delaware Corporation | Multiple mechanisms for modulation of the pi3 kinase pathway |
US20100215644A1 (en) * | 2009-02-25 | 2010-08-26 | Nodality, Inc. A Delaware Corporation | Analysis of nodes in cellular pathways |
US8242248B2 (en) * | 2009-03-23 | 2012-08-14 | Nodality, Inc. | Kits for multiparametric phospho analysis |
US8187885B2 (en) * | 2009-05-07 | 2012-05-29 | Nodality, Inc. | Microbead kit and method for quantitative calibration and performance monitoring of a fluorescence instrument |
US20100297676A1 (en) * | 2009-05-20 | 2010-11-25 | Nodality, Inc. | Methods for diagnosis, prognosis and methods of treatment |
US9459246B2 (en) | 2009-09-08 | 2016-10-04 | Nodality, Inc. | Induced intercellular communication |
GB201308271D0 (en) * | 2013-05-08 | 2013-06-12 | Nat Univ Ireland | Semi-automated whole blood immuno potency assay |
WO2016023008A1 (en) * | 2014-08-07 | 2016-02-11 | The General Hospital Corporation | Platelet-targeted microfluidic isolation of cells |
CA3213163A1 (en) | 2021-03-25 | 2022-09-29 | Iovance Biotherapeutics, Inc. | Methods and compositions for t-cell coculture potency assays and use with cell therapy products |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4902613A (en) | 1984-05-14 | 1990-02-20 | Becton, Dickinson And Company | Lysing agent for analysis of peripheral blood cells |
US4654312A (en) * | 1984-05-14 | 1987-03-31 | Becton, Dickinson And Company | Lysing agent for analysis of peripheral blood cells |
US5098849A (en) * | 1988-07-13 | 1992-03-24 | Becton Dickinson And Company | Material and method to reduce non-specific binding of a labelled material |
WO1993005478A1 (en) * | 1991-08-28 | 1993-03-18 | Becton, Dickinson & Company | Gravitational attractor engine for adaptively autoclustering n-dimensional data streams |
US5597563A (en) | 1992-09-04 | 1997-01-28 | Beschorner; William E. | Method induction of antigen-specific immune tolerance |
US5627025A (en) | 1994-08-12 | 1997-05-06 | The Rockefeller University | Method for the identification of compounds capable of abrogating human immunodeficiency virus (HIV) infection of dendritic cells and T-lymphocytes |
US5648219A (en) | 1995-06-07 | 1997-07-15 | Zymogenetics, Inc. | Immortalized dendritic cells |
US5698679A (en) | 1994-09-19 | 1997-12-16 | National Jewish Center For Immunology And Respiratory Medicine | Product and process for targeting an immune response |
US5648248A (en) | 1994-12-30 | 1997-07-15 | Boehringer Ingelheim International Gmbh | Methods for producing differentiated cells from immature hematopoietic cells |
US5643786A (en) | 1995-01-27 | 1997-07-01 | The United States Of America As Represented By The Department Of Health And Human Services | Method for isolating dendritic cells |
US5788963A (en) | 1995-07-31 | 1998-08-04 | Pacific Northwest Cancer Foundation | Isolation and/or preservation of dendritic cells for prostate cancer immunotherapy |
US6080409A (en) | 1995-12-28 | 2000-06-27 | Dendreon Corporation | Immunostimulatory method |
JP2000505650A (ja) | 1996-02-08 | 2000-05-16 | アメリカ合衆国 | 樹状突起細胞を形質転換し、そしてt細胞を活性化するための方法及び組成物 |
JP2001502670A (ja) | 1996-10-09 | 2001-02-27 | カンタベリー ヘルス リミテッド | 樹状細胞に特異的な抗体 |
CA2268284A1 (en) | 1996-10-10 | 1998-04-16 | Duke University | Method of producing a thymic microenvironment that supports the development of dendritic cells |
-
1998
- 1998-09-22 US US09/158,406 patent/US6495333B1/en not_active Expired - Lifetime
-
1999
- 1999-09-21 JP JP2000571267A patent/JP4450998B2/ja not_active Expired - Fee Related
- 1999-09-21 WO PCT/US1999/021731 patent/WO2000017657A1/en active IP Right Grant
- 1999-09-21 DE DE69917051T patent/DE69917051T2/de not_active Expired - Lifetime
- 1999-09-21 EP EP99946994A patent/EP1116037B1/de not_active Expired - Lifetime
- 1999-09-21 AT AT99946994T patent/ATE266204T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2000017657A1 (en) | 2000-03-30 |
JP4450998B2 (ja) | 2010-04-14 |
US6495333B1 (en) | 2002-12-17 |
DE69917051T2 (de) | 2004-09-02 |
WO2000017657A9 (en) | 2000-08-17 |
ATE266204T1 (de) | 2004-05-15 |
JP2002525606A (ja) | 2002-08-13 |
EP1116037B1 (de) | 2004-05-06 |
EP1116037A1 (de) | 2001-07-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |