CN111387343A - High-biological-activity feed additive and preparation method thereof - Google Patents
High-biological-activity feed additive and preparation method thereof Download PDFInfo
- Publication number
- CN111387343A CN111387343A CN201910280394.3A CN201910280394A CN111387343A CN 111387343 A CN111387343 A CN 111387343A CN 201910280394 A CN201910280394 A CN 201910280394A CN 111387343 A CN111387343 A CN 111387343A
- Authority
- CN
- China
- Prior art keywords
- feed
- feed additive
- bioactivity
- parts
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003674 animal food additive Substances 0.000 title claims abstract description 45
- 230000000694 effects Effects 0.000 title abstract description 18
- 238000002360 preparation method Methods 0.000 title abstract description 6
- 239000002245 particle Substances 0.000 claims abstract description 41
- 241001465754 Metazoa Species 0.000 claims abstract description 40
- 239000000463 material Substances 0.000 claims abstract description 27
- 230000000975 bioactive effect Effects 0.000 claims abstract description 26
- 239000008157 edible vegetable oil Substances 0.000 claims abstract description 18
- 239000000853 adhesive Substances 0.000 claims abstract description 11
- 230000001070 adhesive effect Effects 0.000 claims abstract description 10
- 241000894006 Bacteria Species 0.000 claims description 33
- 102000004190 Enzymes Human genes 0.000 claims description 22
- 108090000790 Enzymes Proteins 0.000 claims description 22
- 229940088598 enzyme Drugs 0.000 claims description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 22
- 239000008187 granular material Substances 0.000 claims description 21
- 239000000203 mixture Substances 0.000 claims description 16
- 239000003921 oil Substances 0.000 claims description 15
- 235000019198 oils Nutrition 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 13
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 12
- 239000006041 probiotic Substances 0.000 claims description 12
- 235000018291 probiotics Nutrition 0.000 claims description 12
- 238000001035 drying Methods 0.000 claims description 11
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 10
- 239000011324 bead Substances 0.000 claims description 9
- 239000011521 glass Substances 0.000 claims description 9
- 241000193830 Bacillus <bacterium> Species 0.000 claims description 8
- 108091005804 Peptidases Proteins 0.000 claims description 7
- 239000004365 Protease Substances 0.000 claims description 7
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims description 7
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 7
- 238000005507 spraying Methods 0.000 claims description 7
- 241000193171 Clostridium butyricum Species 0.000 claims description 6
- 229910021536 Zeolite Inorganic materials 0.000 claims description 6
- 235000014655 lactic acid Nutrition 0.000 claims description 6
- 239000004310 lactic acid Substances 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 239000010457 zeolite Substances 0.000 claims description 6
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 5
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 5
- 235000019486 Sunflower oil Nutrition 0.000 claims description 5
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 5
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 5
- 235000015278 beef Nutrition 0.000 claims description 5
- 239000002600 sunflower oil Substances 0.000 claims description 5
- 235000020238 sunflower seed Nutrition 0.000 claims description 5
- 239000003760 tallow Substances 0.000 claims description 5
- 239000010497 wheat germ oil Substances 0.000 claims description 5
- 108010011619 6-Phytase Proteins 0.000 claims description 4
- 108010059892 Cellulase Proteins 0.000 claims description 4
- 239000004366 Glucose oxidase Substances 0.000 claims description 4
- 108010015776 Glucose oxidase Proteins 0.000 claims description 4
- 102000004882 Lipase Human genes 0.000 claims description 4
- 108090001060 Lipase Proteins 0.000 claims description 4
- 102000016943 Muramidase Human genes 0.000 claims description 4
- 108010014251 Muramidase Proteins 0.000 claims description 4
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 claims description 4
- 240000008042 Zea mays Species 0.000 claims description 4
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 4
- 235000005822 corn Nutrition 0.000 claims description 4
- 229940116332 glucose oxidase Drugs 0.000 claims description 4
- 235000019420 glucose oxidase Nutrition 0.000 claims description 4
- 229960000274 lysozyme Drugs 0.000 claims description 4
- 239000004325 lysozyme Substances 0.000 claims description 4
- 235000010335 lysozyme Nutrition 0.000 claims description 4
- 229940085127 phytase Drugs 0.000 claims description 4
- 239000004367 Lipase Substances 0.000 claims description 3
- 229940106157 cellulase Drugs 0.000 claims description 3
- -1 lard Substances 0.000 claims description 3
- 229940040461 lipase Drugs 0.000 claims description 3
- 235000019421 lipase Nutrition 0.000 claims description 3
- 239000000969 carrier Substances 0.000 claims 3
- 238000010521 absorption reaction Methods 0.000 abstract description 9
- 235000015097 nutrients Nutrition 0.000 abstract description 7
- 208000035240 Disease Resistance Diseases 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 description 19
- 230000008569 process Effects 0.000 description 10
- 230000004083 survival effect Effects 0.000 description 8
- 241000238017 Astacoidea Species 0.000 description 7
- 230000004071 biological effect Effects 0.000 description 7
- 239000000378 calcium silicate Substances 0.000 description 6
- 229910052918 calcium silicate Inorganic materials 0.000 description 6
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 description 6
- 235000019419 proteases Nutrition 0.000 description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- HCWCAKKEBCNQJP-UHFFFAOYSA-N magnesium orthosilicate Chemical compound [Mg+2].[Mg+2].[O-][Si]([O-])([O-])[O-] HCWCAKKEBCNQJP-UHFFFAOYSA-N 0.000 description 4
- 239000000391 magnesium silicate Substances 0.000 description 4
- 229910052919 magnesium silicate Inorganic materials 0.000 description 4
- 235000019792 magnesium silicate Nutrition 0.000 description 4
- 241000186660 Lactobacillus Species 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 229940039696 lactobacillus Drugs 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 230000000433 anti-nutritional effect Effects 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000000593 degrading effect Effects 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 235000012631 food intake Nutrition 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 239000010815 organic waste Substances 0.000 description 2
- 229930195730 Aflatoxin Natural products 0.000 description 1
- XWIYFDMXXLINPU-UHFFFAOYSA-N Aflatoxin G Chemical compound O=C1OCCC2=C1C(=O)OC1=C2C(OC)=CC2=C1C1C=COC1O2 XWIYFDMXXLINPU-UHFFFAOYSA-N 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 241000238557 Decapoda Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 241000194033 Enterococcus Species 0.000 description 1
- 108090000526 Papain Proteins 0.000 description 1
- 241000235342 Saccharomycetes Species 0.000 description 1
- 239000004115 Sodium Silicate Substances 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 240000008866 Ziziphus nummularia Species 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000005409 aflatoxin Substances 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000003631 expected effect Effects 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 230000008944 intestinal immunity Effects 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 239000010699 lard oil Substances 0.000 description 1
- 235000019626 lipase activity Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000010461 other edible oil Substances 0.000 description 1
- 229940055729 papain Drugs 0.000 description 1
- 235000019834 papain Nutrition 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000007420 reactivation Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 description 1
- 229910052911 sodium silicate Inorganic materials 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/28—Silicates, e.g. perlites, zeolites or bentonites
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Inorganic Chemistry (AREA)
- Fodder In General (AREA)
Abstract
The invention belongs to the technical field of animal feed, and particularly relates to a high-bioactivity feed additive and a preparation method thereof. A high-bioactivity feed additive comprises, by weight, 100 parts of a bioactive material, 400-1000 parts of a carrier, 30-100 parts of edible oil and 4-20 parts of an adhesive, wherein the particle size of the carrier is 20-150 microns, the thermal conductivity of the carrier is less than or equal to 0.085 w/m.k (25 ℃), and the animal feed with the high-bioactivity feed additive is reasonably added, so that the absorption effect of cultured animals on nutrient components in the feed can be effectively improved, and the growth rate and disease resistance of the cultured animals are improved.
Description
Technical Field
The invention belongs to the technical field of animal feed, and particularly relates to a high-bioactivity feed additive and a preparation method thereof.
Background
In the feeding process of animals, how to improve the absorption of the animals to the effective components of the feed is vital, and for feed processing enterprises, one idea is to add probiotics and feed enzymes into basic feed individually or in a compound way, so that the absorption capacity of the animals to the nutrient texture is improved through the survival of the probiotics and the feed enzymes in the bodies of the animals, and the feed has a health-care function on the animals, thereby achieving the expected effect.
However, in actual operation, because different beneficial bacteria and bioactive substances produced by feed enzymes have different heat resistance limits, if the beneficial bacteria and the feed enzymes are added at the beginning of feed processing, because the processing temperature of the feed is generally 80-150 ℃ and the processing time is about 5-40 min, the biological activities of the beneficial bacteria and the feed enzymes can be rapidly reduced or even inactivated in the feed processing process, and cannot meet the actual use requirements, for example, lactic acid bacteria can be inactivated under the processing condition of 40-60 ℃ (general lactic acid bacteria are inactivated at the temperature higher than 40 ℃, enterococcus is inactivated at the temperature higher than 60 ℃), and bacillus cannot survive under the condition that the temperature exceeds 100 ℃ and the time is longer than 40 min; therefore, beneficial bacteria such as lactobacillus and bacillus cannot be applied to the shrimp and crab feed process and the expanded feed process.
The fermentation liquor is mixed with other components of the feed to obtain a product in a surface spraying mode, and the fermentation liquor contains a certain amount of water, so that beneficial bacteria are in an active state and are not dormant, and the survival rate of the feed is extremely low in the storage process; beneficial bacteria and feed enzymes easily cause feed mildew; when the liquid feed enzyme is mixed with protease, the protease may destroy other active substances, and the probiotics and the feed enzyme cannot be widely applied to the feed industry due to the limitation of the beneficial bacteria and the feed enzyme.
Disclosure of Invention
In order to solve the problems, the invention provides a high-bioactivity feed additive, an animal feed reasonably added with the high-bioactivity feed additive can effectively improve the absorption effect of animals on nutrient components in the feed, improve the growth rate of the animals, and provide a preparation method suitable for industrial production.
The invention is realized by adopting the following technical scheme:
a high-bioactivity feed additive comprises, by weight, 100 parts of a bioactive material, 400-1000 parts of a carrier, 30-100 parts of edible oil and 4-20 parts of an adhesive, wherein the particle size of the carrier is 20-150 microns, and the thermal conductivity of the carrier is less than or equal to 0.085 w/m.k (25 ℃).
Preferably, the bioactive material comprises probiotics, and the probiotics is one or more of bacillus, lactic acid bacteria, clostridium butyricum, yeast and the like. The bacillus has stronger protease, amylase and lipase activities, also has enzymes for degrading complex carbohydrates in the feed, can destroy cell walls of plant feed cells, promote release of nutrients of the cells, eliminate anti-nutritional factors in the feed and reduce barriers of the anti-nutritional factors to animal digestion and utilization; the lactobacillus can improve the intestinal immunity, promote gastric secretion and enhance the digestion function; degrading organic wastes such as residual bait, excrement and the like in the pond; the bait coefficient is reduced, and the culture period is shortened; inhibiting harmful bacteria in water; has extremely strong low oxygen-dissolving reproductive capacity; the clostridium butyricum can be set in the aquatic animal for 72 hours, repair the intestinal mucosa of the aquatic animal, prevent enteritis, and improve the problems of excrement dragging, floating and the like of the animal; increasing food intake and removing aflatoxin in the feed; the yeast has good feeding attraction and provides rich mycoprotein; the food intake of the animals is increased, and the rapid growth of the animals is promoted; the micro-ecological environment of the aquatic animals can be adjusted; improving the absorption and utilization rate of animals to the feed and enhancing the immunity.
Preferably, the bioactive material comprises feed enzyme, and the feed enzyme is one or more of glucose oxidase, phytase, protease, lysozyme, cellulase, lipase and the like. They have various physiological activities of helping digestion and absorption of feed, inhibiting and killing germs, viruses and the like.
Bioactive materials such as probiotics, feed enzymes and the like can effectively regulate water quality, have strong water purification capacity, inhibit harmful bacteria in water, reduce organic waste, purify suspended matters in water and improve the transparency of water.
The carrier forms a coating effect on bioactive materials such as probiotics, feed enzymes and the like, and edible oil is sprayed on the surfaces of the carrier and bioactive material particles, so that the steam ground penetration can be prevented, the bioactive materials are protected from being influenced by high-temperature and high-humidity processing conditions in the feed processing process, the feed additive with high bioactivity is ensured to be added at the beginning stage of feed processing, the bioactivity of the bioactive materials in the obtained feed finished product reaches more than 70%, the absorption effect of animals on nutrient components in the feed can be effectively improved, the growth rate and the health condition of the animals are improved, and the feed additive is the most ideal scheme for replacing feed antibiotics.
In a preferred scheme, the carrier is one or more of low-thermal-conductivity-coefficient materials such as silicate particles, hollow glass beads, zeolite powder particles and the like. The silicate particles can be selected from calcium silicate, magnesium silicate, sodium silicate and the like, the thermal conductivity coefficient of the silicate is 0.045-0.052 w/m.k (25 ℃), the thermal conductivity coefficient of the hollow glass beads can be selected from 0.025-0.04 w/m.k (25 ℃), the thermal conductivity coefficient of the zeolite powder is 0.02-0.025 w/m.k (25 ℃), neither the silicate particles nor the hollow glass beads can be digested by animals, and can be directly discharged along with excrement of animals, and the zeolite powder can relieve and prevent the toxic action of some compounds, heavy metals and ammonia in the digestive tract of the animals.
Preferably, the food additive further comprises 0.1-60 parts of trehalose by weight. The trehalose has the effects of protecting the integrity and the activity of cells and promoting the reactivation of dormant beneficial bacteria in a severe environment, and can protect the activity of the beneficial bacteria and feed enzymes from losing in the feed processing process.
Preferably, the edible oil is one or more of refined sunflower oil, sunflower seed oil, beef tallow, lard, wheat germ oil, corn germ oil and other edible oils with low thermal conductivity coefficient, wherein the thermal conductivity coefficient of the refined sunflower oil, sunflower seed oil, wheat germ oil and corn germ oil is 0.2-0.22 w/m.k (25 ℃), and the thermal conductivity coefficient of the beef tallow and lard is 0.18-0.2 w/m.k (25 ℃), and the thermal conductivity coefficient of the vegetable oil is far smaller than that of water, so that the biological activity of the bioactive material can be further improved during feed processing.
A preparation method of a high-bioactivity feed additive comprises the following steps:
s1, mixing, namely uniformly mixing the bioactive material, the adhesive and the carrier according to a proportion to prepare a mixture;
s2, preparing a granular material, adding water into the mixture, granulating, and drying to obtain the granular material, wherein the granulating and drying temperatures are both 40-60 ℃;
s3, wrapping oil, spraying the edible oil on the surface of the granules to enable the granules to absorb the edible oil, and thus obtaining the high-bioactivity feed additive.
The edible oil is mixed with the granules in a spraying mode, so that the edible oil can prevent the wet and hot steam from being absorbed by the bacteria and enzyme granules in the granulation process, and the protection effect on the bacteria and the enzyme is enhanced.
Preferably, in step S2, 0.05 to 0.2 parts by weight of water is added to 1 part by weight of the mixture. The addition amount of the water is determined according to the properties of the materials and the requirements of the granulation process so as to meet the actual production requirements. Less water is beneficial to the prepared granular material with less water content, and the difficulty of the drying process is reduced.
Preferably, in the step S2, the particle size of the particle material is 0.3 to 1.5 mm. The feed intake of small aquatic animals such as crayfish is less, the particle size of the limited granular material is 0.3-1.5 mm, the effective intake of the high-biological-activity feed additive when crayfish eats can be guaranteed, namely the effective intake of probiotics and feed enzymes is guaranteed, and the effect of the probiotics and the feed enzymes is guaranteed to meet the established requirements.
An animal feed comprises the high-bioactivity feed additive. Due to the existence of the high-biological-activity feed additive, the absorption effect of animals on nutrient components in the feed can be effectively improved, the growth rate of the animals is improved, the feed coefficient is reduced, the disease resistance of the animals is improved, and the water environment is improved.
The invention has the beneficial effects that:
1. according to the high-bioactivity feed additive, the carrier forms a coating effect on bioactive materials such as probiotics and feed enzymes, and edible oil is sprayed on the surfaces of the carrier and the bioactive materials, so that the bioactive materials can be protected from being influenced by high-temperature processing conditions in the feed processing process, and the bioactivity of the bioactive materials in the feed finished product obtained after the high-bioactivity feed additive is added at the beginning stage of feed processing is ensured to be more than 70%.
2. The high-bioactivity feed additive provided by the invention has the advantages that silicate particles, hollow glass beads and zeolite particles cannot be digested by animals and can be directly discharged along with excrement of the animals.
3. The trehalose can protect the integrity rate and the biological activity of living cells under severe conditions, and is beneficial to improving the revival rate of beneficial bacteria.
Detailed Description
The technical solutions in the examples will be clearly and completely described below. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without any inventive step, are within the scope of the present invention.
In the following embodiments 1 to 7, the bioactive materials refer to bacillus, lactic acid bacteria, clostridium butyricum, yeast, glucose oxidase, phytase, protease, lysozyme, cellulase and lipase in table 1; the edible oil refers to refined sunflower oil, sunflower seed oil, beef tallow, lard, wheat germ oil and corn germ oil in the table 1; the adhesive is purchased from animal feed adhesive produced by Dongyang commercial and trade company of jujube village.
Example 1
A high-bioactivity feed additive comprises the components shown in the table 1 in parts by weight, wherein the silicate particles are calcium silicate particles, the particle size of the calcium silicate particles is 20-150 um, and the heat conductivity coefficient of the calcium silicate particles is 0.045-0.052 w/m.k (25 ℃).
Example 2
A high-biological-activity feed additive comprises the components shown in the table 1 in parts by weight, wherein the particle size of zeolite powder particles is 20-80 um, and the heat conductivity coefficient is 0.02-0.025 w/m.k (25 ℃).
In the above embodiments 1-2, a high-bioactivity feed additive is prepared by the following steps:
s1, mixing, namely uniformly mixing the bioactive material, the carrier and the adhesive in proportion to prepare a mixture;
s2, preparing a granular material, adding water into the mixture, adding 0.2 part of water into 1 part of the mixture, granulating and drying to obtain the granular material with the grain diameter of 0.3-1.5 mm, wherein the granulating and drying temperatures are 40-46 ℃;
s3, wrapping oil, and spraying edible oil on the surfaces of the particles for 30 min-1 h to prepare the high-bioactivity feed additive.
Example 3
A high-bioactivity feed additive comprises the components shown in the table 1 in parts by weight, wherein silicate particles are magnesium silicate particles, the particle size of the magnesium silicate particles is 60-150 mu m, and the heat conductivity coefficient of the magnesium silicate particles is 0.45-0.6 w/m.k (25 ℃).
Example 4
A high-bioactivity feed additive comprises the components shown in the table 1 in parts by weight, wherein the particle size of calcium carbonate particles is 20-150 um, and the heat conductivity coefficient is 0.045-0.052 w/m.k (25 ℃).
In the above embodiments 3 to 4, a high-bioactivity feed additive is prepared by the following steps:
s1, mixing, namely uniformly mixing the bioactive material, the carrier and the adhesive in proportion to prepare a mixture;
s2, preparing a granular material, adding water into the mixture, adding 0.05 part of water into 1 part of the mixture, granulating and drying to obtain the granular material with the particle size of 0.3-1.5 mm, wherein the granulating and drying temperatures are 56-60 ℃;
s3, wrapping oil, and spraying the edible oil on the surface of the granules to obtain the feed additive with high biological activity.
Example 5
A high-bioactivity feed additive comprises the components shown in the table 1 in parts by weight, wherein the silicate particles are calcium silicate particles, the particle size of the calcium silicate particles is 50-150 um, and the heat conductivity coefficient is 0.045-0.052 w/m.k (25 ℃); the hollow glass beads have a particle size of 50-150 um and a thermal conductivity of 0.03-0.04 w/m.k (25 ℃).
Example 6
The feed additive with high biological activity comprises the components shown in the table 1 in parts by weight, wherein the particle size of the hollow glass beads is 20-80 um, and the heat conductivity coefficient is 0.025-0.03 w/m.k (25 ℃).
Example 7
The feed additive with high biological activity comprises the components shown in the table 1 in parts by weight, wherein the particle size of the hollow glass beads is 20-80 um, and the heat conductivity coefficient is 0.025-0.03 w/m.k (25 ℃).
In the above embodiments 5 to 7, a high-bioactivity feed additive is prepared by the following steps:
s1, mixing, namely uniformly mixing the bioactive material, the carrier and the adhesive in proportion to prepare a mixture;
s2, preparing a granular material, adding water into the mixture, adding 0.15 part of water into 1 part of the mixture, granulating and drying to obtain the granular material with the grain diameter of 0.3-1.5 mm, wherein the granulating and drying temperatures are both 48-52 ℃;
s3, wrapping oil, and spraying the edible oil on the surface of the granules to obtain the feed additive with high biological activity.
TABLE 1 component proportions for examples 1 to 7
| Item (kg) | Example 1 | Example 2 | Example 3 | Example 4 | Example 5 | Example 6 | Example 7 |
| Bacillus | 100 | 0 | 0 | 0 | 10 | 50 | 20 |
| Lactic acid bacteria | 0 | 80 | 0 | 0 | 10 | 20 | 15 |
| Clostridium butyricum | 0 | 0 | 60 | 0 | 40 | 10 | 5 |
| Yeast | 0 | 0 | 0 | 20 | 40 | 20 | 5 |
| Glucose oxidase | 0 | 20 | 0 | 15 | 0 | 0 | 5 |
| Phytase | 0 | 0 | 10 | 5 | 0 | 0 | 10 |
| Protease enzyme | 0 | 0 | 10 | 5 | 0 | 0 | 10 |
| Lysozyme | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cellulase enzymes | 0 | 0 | 5 | 15 | 0 | 0 | 15 |
| Lipase enzyme | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Papain | 0 | 0 | 10 | 9 | 0 | 0 | 5 |
| Silicate particles | 700 | 0 | 400 | 0 | 500 | 0 | 0 |
| Calcium carbonate particles | 0 | 0 | 0 | 500 | 0 | 0 | 0 |
| Hollow glass bead | 0 | 0 | 0 | 0 | 500 | 700 | 800 |
| Zeolite powder particles | 0 | 600 | 0 | 0 | 0 | 0 | 0 |
| Adhesive agent | 8 | 6 | 10 | 12 | 16 | 4 | 20 |
| Refining sunflower oil | 20 | 0 | 0 | 0 | 0 | 0 | 0 |
| Sunflower seed oil | 10 | 70 | 0 | 0 | 0 | 0 | 0 |
| Beef tallow | 20 | 0 | 50 | 0 | 0 | 0 | 0 |
| Lard oil | 10 | 0 | 0 | 30 | 0 | 0 | 0 |
| Wheat germ oil | 10 | 0 | 0 | 0 | 45 | 30 | 0 |
| Corn germ oil | 30 | 0 | 0 | 0 | 0 | 30 | 85 |
| Trehalose | 0 | 10 | 0 | 0.1 | 0 | 40 | 60 |
In the experiment, the high-bioactivity feed additives of the examples 1 to 7 are mixed with 1000kg of basal feed, the mixture is divided into two groups for experiment, and the animal feed of the experiment groups 1 to 7 is produced at the temperature of 100 ℃;
and adding the same amount of untreated beneficial bacteria such as bacillus, lactobacillus, clostridium butyricum and saccharomycetes to the basic feed under the same condition as that of the experimental group 1-7 to obtain the animal feed of a control group 1, a control group 2, a control group 3, a control group 4, a control group 5, a control group 6 and a control group 7.
Testing the survival rates of beneficial bacteria in the experimental groups 1-7 and the control groups 1-7, weighing 1g of animal feed of the experimental groups 1-8 and the control groups 1-8 respectively during testing, measuring the total bacteria number by using a blood counting plate, and diluting by 107～108After multiplication, the dilution multiple is properly selected according to the actual living bacteria survival effect, the living bacteria are respectively cultured under the aerobic condition and the anaerobic condition, the number of the living bacteria obtained after the culture is tested, the results of more living bacteria under the aerobic condition and the anaerobic condition are taken for each group to be calculated, the survival rate of the beneficial bacteria is the number of the living bacteria/the total number of the bacteria, and the test results are shown in table 2:
TABLE 2 survival rate of beneficial bacteria
| Item | Survival rate of beneficial bacteria (%) | Item | Survival rate of beneficial bacteria (%) |
| Experimental group 1 | 76 | Control group 1 | 4.2 |
| Experimental group 2 | 75 | Control group 2 | 3.6 |
| Experimental group 3 | 71 | Control group 3 | 2.5 |
| Experimental group 4 | 73 | Control group 4 | 2.8 |
| Experimental group 5 | 85 | Control group 5 | 0 |
| Experimental group 6 | 82 | Control group 6 | 0 |
| Experimental group 7 | 84 | Control group 7 | 0 |
The results of feeding 100 crayfish in the growth period at a rate of 3% of the weight of crayfish per day with the animal feeds of the experimental groups 1 to 7 and the control group 1 are shown in table 3, in which the feeding time per day is the same for each group, and the average weight of crayfish is compared after 15 days.
TABLE 3 average crayfish weight
According to the results, the high-biological-activity feed additive can effectively improve the absorption effect of animals on the nutrient components in the feed and can obviously improve the growth rate of crayfish.
Claims (10)
1. The high-bioactivity feed additive is characterized by comprising 100 parts by weight of bioactive materials, 400-1000 parts by weight of carriers, 30-100 parts by weight of edible oil and 4-20 parts by weight of adhesives, wherein the particle size of the carriers is 20-150 microns, and the thermal conductivity of the carriers is less than or equal to 0.085 w/m.k (25 ℃).
2. The feed additive with high bioactivity according to claim 1, wherein the bioactive material comprises probiotics, and the probiotics is one or more of bacillus, lactic acid bacteria, clostridium butyricum, yeast and the like.
3. The feed additive with high bioactivity as claimed in claim 1, wherein the bioactive material comprises feed enzyme, and the feed enzyme is one or more of glucose oxidase, phytase, protease, lysozyme, cellulase, lipase, etc.
4. The feed additive with high bioactivity as claimed in claim 1, wherein the carrier is one or more of silicate particles, hollow glass beads, zeolite powder particles and other materials with low thermal conductivity coefficient.
5. The feed additive with high bioactivity according to claim 1, further comprising 0.1-60 parts by weight of trehalose.
6. The feed additive with high bioactivity as claimed in claim 1, wherein the edible oil is one or more of edible oil with low thermal conductivity such as refined sunflower oil, sunflower seed oil, beef tallow, lard, wheat germ oil and corn germ oil.
7. A method for preparing the highly bioactive feed additive according to claim 1, comprising the steps of:
s1, mixing, namely uniformly mixing the bioactive material, the adhesive and the carrier according to a proportion to prepare a mixture;
s2, preparing a granular material, adding water into the mixture, granulating, and drying to obtain the granular material, wherein the granulating and drying temperatures are both 40-60 ℃;
s3, wrapping oil, spraying the edible oil on the surface of the granules to enable the granules to absorb the edible oil, and thus obtaining the high-bioactivity feed additive.
8. The method for preparing a feed additive with high bioactivity according to claim 7, wherein in step S2, 0.05-0.2 parts by weight of water is added to 1 part by weight of the mixture.
9. The method for preparing a feed additive with high bioactivity according to claim 7, wherein in step S2, the particle size of the granules is 0.3-1.5 mm.
10. An animal feed comprising the highly bioactive feed additive of claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910280394.3A CN111387343A (en) | 2019-04-09 | 2019-04-09 | High-biological-activity feed additive and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910280394.3A CN111387343A (en) | 2019-04-09 | 2019-04-09 | High-biological-activity feed additive and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111387343A true CN111387343A (en) | 2020-07-10 |
Family
ID=71410738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910280394.3A Pending CN111387343A (en) | 2019-04-09 | 2019-04-09 | High-biological-activity feed additive and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111387343A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1615086A (en) * | 2002-01-15 | 2005-05-11 | 巴斯福股份公司 | Granulates containing feed-enzymes |
| CN104928278A (en) * | 2015-07-13 | 2015-09-23 | 通威股份有限公司 | Preparation method for composite bacillus microcapsule preparations |
| CN105994954A (en) * | 2016-05-13 | 2016-10-12 | 杭州康德权饲料有限公司 | Microencapsulated microecological preparation and preparation method thereof |
| CN107080053A (en) * | 2017-03-21 | 2017-08-22 | 四川新华扬山野生物有限公司 | A kind of heat-resistance type coating bioactive substance and preparation method thereof |
-
2019
- 2019-04-09 CN CN201910280394.3A patent/CN111387343A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1615086A (en) * | 2002-01-15 | 2005-05-11 | 巴斯福股份公司 | Granulates containing feed-enzymes |
| CN104928278A (en) * | 2015-07-13 | 2015-09-23 | 通威股份有限公司 | Preparation method for composite bacillus microcapsule preparations |
| CN105994954A (en) * | 2016-05-13 | 2016-10-12 | 杭州康德权饲料有限公司 | Microencapsulated microecological preparation and preparation method thereof |
| CN107080053A (en) * | 2017-03-21 | 2017-08-22 | 四川新华扬山野生物有限公司 | A kind of heat-resistance type coating bioactive substance and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101449744B (en) | Multifunctional biology aquatic feedstuff additive | |
| CN1281147C (en) | Microbial fodder additive and its preparing method and use | |
| CN104285825B (en) | A kind of recycling cow dung prepares the method for fermenting bed padding | |
| CN103004659B (en) | Fish fry culturing method for four major Chinese carps | |
| CN102511662A (en) | Composite probiotic microorganism feed additive, preparation method and application thereof | |
| CN111418713B (en) | Feed for regulating intestinal health of micropterus salmoides | |
| CN105399219A (en) | Water quality regulation and control compound microbial preparation and production method thereof | |
| CN104664049A (en) | A kind of microbial fermentation organic feed | |
| CN105341530A (en) | Clean type special compound feed for stichopus japonicus and processing method of clean type special compound feed | |
| CN112205545A (en) | Preparation method of liver-protecting intestine-protecting fermented penaeus vannamei granule | |
| CN111728083A (en) | A kind of bacteria-enzyme fusion fermentation culture capable of improving the intestinal function of livestock and poultry and preparation method thereof | |
| CN104664131A (en) | Organic feed for sea cucumber farming | |
| CN112493372A (en) | Livestock feed additive, application thereof and broiler feed | |
| CN112655839A (en) | Exogenous enzyme composite preparation and preparation method and application thereof | |
| CN111387343A (en) | High-biological-activity feed additive and preparation method thereof | |
| CN108587966B (en) | Application of a pure natural plant-derived EM bacteria culture medium and its fermented products in aquaculture | |
| CN104664062A (en) | Preparation method of polypeptide microbial aquatic feed | |
| CN110063425A (en) | A kind of sea cucumber, prawn and formula of jellyfish pond three-dimensional culture ecological feed and preparation method thereof | |
| CN108813111A (en) | Secondary enzymolysis ocean substance prepares method of pig starter feed and products thereof and application | |
| CN104450576A (en) | Liquid preparation of bacillus pumilus and bdellovibrio and application thereof | |
| CN114287515A (en) | Method for preparing biological feed by using wheat processing by-products | |
| CN104673775A (en) | Micro-ecological preparation for repairing aquiculture water environment and preparation method of micro-ecological preparation | |
| CN114766613A (en) | Biological agent suitable for high-density culture of loaches and preparation method thereof | |
| CN114668070A (en) | Multifunctional composite biological feed for feeding and preparation method thereof | |
| CN113068773A (en) | Feed additive for replacing antibiotics and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200710 |