CN109908061B - Anti-dandruff shampoo rich in foam and preparation method thereof - Google Patents

Abstract

The invention discloses an anti-dandruff shampoo rich in foam, wherein an amino acid surfactant is a compound of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl aminoacetate, and the mass ratio is 1: 3-5: 10-20, and meanwhile, the pomegranate rind extract is added, so that unexpected technical effects are achieved in the aspect of foam richness; the pomegranate bark extract obtained by the specific extraction method enables the shampoo of the invention to have excellent anti-dandruff effect.

Description

Anti-dandruff shampoo rich in foam and preparation method thereof

Technical Field

The invention relates to the field of daily cosmetics, in particular to an anti-dandruff shampoo rich in foam and a preparation method thereof.

Background

The shampoo is used for cleaning human body secreted oil, sweat stain, cells detached from scalp and foreign dust, microorganism and unpleasant odor etc. attached on scalp and hair, keeping scalp and hair clean and hair beautiful. The shampoo is also called shampoo, is a cosmetic washing product for washing hair, and belongs to one of the earliest and fastest-developing products in the personal care market. The development of the shampoo has a long history, people use soap to clean hair before 20 th century and 30 th century, and then liquid shampoo taking surfactant as a base material is disclosed, so that the hardness and water resistance and the mildness of the product are greatly improved. With the improvement of living standard and the rapid development of science and technology, people have higher and higher requirements on the safety of the surfactant of the shampoo.

The shampoo can be roughly divided into five categories, which are respectively: (1) the transparent shampoo is the earliest in appearance and simple in formula, and mainly has a cleaning effect. (2) The pearlescent shampoo has no requirement on transparency, and the pearlescent agent is added in the prior art, namely the pearlescent agent is directly used, and the pearlescent slurry is used. (3) The conditioning shampoo is one of the most popular shampoos at present, and the familiar two-in-one shampoo is one of the shampoos and combines the hair washing and the hair care into a whole to finish the conditioning shampoo at one time. The conditioning shampoo is prepared by adding various conditioning agents on the basis of common shampoo so as to achieve the expected effect. (4) Dandruff removing shampoo is prepared from scalp functional disorder, such as bacterial growth, seborrheic dermatitis, and abnormal proliferation of glial cell. And excessive dandruff can breed more bacteria and fungi, and causes symptoms such as scalp itching and the like. Therefore, some active substances with bacteriostatic and bactericidal effects are often added into shampoo to effectively control dandruff. (5) In the sunscreen shampoo, after the hair is exposed to the radiation of ultraviolet radiation for a long time, some photochemical reactions are generated, which have great influence on the physical and chemical properties of the hair, so that some sunscreen agents are often added into the shampoo to properly prevent the hair from being damaged by the ultraviolet radiation.

The amino acid surfactant is a protein-like mild surfactant, has low irritation, low toxicity, softness, good biodegradability, good affinity to human bodies and the like, meets various requirements of consumers, and draws more and more attention of people. In China, the research on the amino acid type surfactant is relatively late and laggard, and when the amino acid type surfactant is applied to cleaning products, the problem that the amino acid type surfactant is difficult to thicken and even cannot thicken, so that the amino acid type surfactant is difficult to apply is often caused. Therefore, the application rate of amino acid type surfactants in domestic hair products is not so high. At present, various manufacturers add various high molecular polymer thickening agents to solve the problem, but the foam property of the amino acid surfactant is inhibited, so that the application of the amino acid surfactant in hair products is limited.

Although shampoo products with various formulas exist in the current market, the performance difference of different products is large, and the foam performance of a plurality of shampoos needs to be further improved. For example, the prior art discloses a chinese patent application entitled "a mild amino acid shampoo and a preparation method thereof", publication number CN 106176270a, and the amino acid shampoo provided by the invention comprises the following components: fatty alcohol polyoxyethylene amine, coco betaine, alkyl glycoside, amino acid surfactant, water-soluble grease, polyquaternium-10, cocamide monoethanolamine, PEG-120 methyl glucose dioleate, benzoic acid, salicylic acid, glycerol, essence and water. The amino acid shampoo provided by the invention has good foaming and foam stabilizing properties, proper cleaning and washing capacity and good moistening effect; the hair after washing is bright, smooth, elastic and good in combing property; is mild to skin, non-toxic, non-irritant, comfortable and soft. However, the shampoo has single efficacy and is not obvious in the aspect of anti-dandruff effect, and meanwhile, the relationship between the foam performance of the shampoo and the type and the dosage of the amino acid surfactant in the raw materials is large. Therefore, the shampoo product with good dandruff removing effect and good foamability is researched, and has good market prospect.

Disclosure of Invention

Aiming at the defects in the prior art, the invention aims to provide mild shampoo with good anti-dandruff effect and good foamability. The invention is realized by the following technical scheme:

an anti-dandruff shampoo with rich foam is prepared from the following raw materials in percentage by weight: 1-3% of ammonium lauryl alcohol ether sulfate, 1-4% of cocobetaine, 1-5% of cocoalkyl glucoside, 2-10% of amino acid surfactant, 1-2% of pomegranate peel extract, 1-2% of PEG-7 olive oil, 100.1-0.5% of polyquaternium, 0.2-1% of cocoamide monoethanolamine, 0.2-1% of PEG-120 methyl glucose dioleate, 0.01-0.05% of benzoic acid, 0.01-0.05% of salicylic acid, 1-5% of glycerol, 0.3-0.8% of essence, and the balance of water; the amino acid surfactant is a compound of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl amino acid, and the mass ratio of the sodium lauroyl sarcosinate to the sodium myristoyl sarcosinate is 1: 3-5: 10-20.

Preferably, the mild amino acid shampoo is prepared from the following raw materials in percentage by weight: 2% of ammonium lauryl alcohol ether sulfate, 3% of cocobetaine, 2% of cocoalkyl glucoside, 5% of amino acid surfactant, 1% of pomegranate peel extract, 2% of PEG-7 olive oil, 0.5% of polyquaternium-100.25%, 0.5% of cocamide monoethanolamine, 0.5% of PEG-120 methyl glucose dioleate, 0.03% of benzoic acid, 0.03% of salicylic acid, 3% of glycerol, 0.5% of essence and the balance of water; the amino acid surfactant is a compound of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl amino acid, and the mass ratio of the sodium lauroyl sarcosinate to the sodium myristoyl sarcosinate is 1: 5: 20.

preferably, the preparation method of the pomegranate bark extract comprises the following steps:

(1) weighing pulverized pericarpium Granati, adding 75% ethanol solution according to solid-to-liquid ratio g/mL of 1:30, ultrasonic-assisted extracting for 50 min, filtering, extracting the residue for 1 time, mixing filtrates, and concentrating under reduced pressure;

(2) extracting the concentrated solution twice by using equal volume of ethyl acetate, combining the extract solutions, recovering ethyl acetate to half volume, and extracting by using equal volume of sodium hydroxide solution with mass concentration of 4%;

(3) adjusting the pH value of the extract to 4 by using dilute hydrochloric acid, adding a gelatin solution with the mass concentration of 5%, standing overnight, and filtering; collecting precipitate, dissolving with 60% acetone solution, filtering off insoluble substances, and recovering acetone from filtrate;

(4) and (3) after recovering acetone from the filtrate, loading the filtrate to a pretreated polyamide chromatographic column, eluting with 20%, 40% and 60% of absolute ethanol with the volume concentration of 3-6 times of the column volume in sequence, collecting the absolute ethanol eluate, concentrating under reduced pressure, and freeze-drying to obtain the pomegranate bark extract.

The invention relates to a preparation method of an anti-dandruff shampoo rich in foam, which is characterized by comprising the following steps of:

(1) adding water into a reaction cylinder, adding ammonium lauryl ether sulfate, stirring and heating to 75-80 ℃, and completely dissolving to obtain a solution A;

(2) adding coco betaine and coco alkyl glucoside into the solution A, uniformly stirring, cooling to 70-75 ℃, and completely dissolving to obtain a solution B;

(3) adding the amino acid surfactant, the pomegranate peel extract and the polyquaternium-10 into the solution B, uniformly stirring, cooling to 55-65 ℃, adding glycerol, uniformly stirring, and completely dissolving to obtain a solution C;

(4) cooling the solution C to 35-45 ℃, adding PEG-7 olive oil, benzoic acid, salicylic acid and essence, finally adding the cocamide monoethanolamine and the PEG-120 methyl glucose dioleate, uniformly mixing, and discharging to obtain the liquid.

Compared with the prior art, the cosmetic has the beneficial effects that: (1) the amino acid surfactant adopted by the shampoo is a compound of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl aminoacetate, and the mass ratio is 1: 3-5: 10-20, and meanwhile, the pomegranate rind extract is added, so that unexpected technical effects are achieved in the aspect of foam richness; (2) the pomegranate bark extract obtained by the specific extraction method enables the shampoo of the invention to have excellent anti-dandruff effect.

Detailed Description

The present invention will be further specifically described with reference to the following examples.

Example 1:

an anti-dandruff shampoo with rich foam is prepared from the following raw materials in percentage by weight: 2% of ammonium lauryl alcohol ether sulfate, 3% of cocobetaine, 2% of cocoalkyl glucoside, 5% of amino acid surfactant, 1% of pomegranate peel extract, 2% of PEG-7 olive oil, 0.5% of polyquaternium-100.25%, 0.5% of cocamide monoethanolamine, 0.5% of PEG-120 methyl glucose dioleate, 0.03% of benzoic acid, 0.03% of salicylic acid, 3% of glycerol, 0.5% of essence and the balance of water; the amino acid surfactant is a compound of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl amino acid, and the mass ratio of the sodium lauroyl sarcosinate to the sodium myristoyl sarcosinate is 1: 5: 20.

the preparation method of the pomegranate bark extract comprises the following steps:

(1) weighing pulverized pericarpium Granati, adding 75% ethanol solution according to solid-to-liquid ratio g/mL of 1:30, ultrasonic-assisted extracting for 50 min, filtering, extracting the residue for 1 time, mixing filtrates, and concentrating under reduced pressure;

(2) extracting the concentrated solution twice by using equal volume of ethyl acetate, combining the extract solutions, recovering ethyl acetate to half volume, and extracting by using equal volume of sodium hydroxide solution with mass concentration of 4%;

(3) adjusting the pH value of the extract to 4 by using dilute hydrochloric acid, adding a gelatin solution with the mass concentration of 5%, standing overnight, and filtering; collecting precipitate, dissolving with 60% acetone solution, filtering off insoluble substances, and recovering acetone from filtrate;

(4) and (3) after recovering acetone from the filtrate, loading the filtrate to a pretreated polyamide chromatographic column, eluting with 20%, 40% and 60% of absolute ethanol in a volume concentration of 5 times of the column volume in sequence, collecting the absolute ethanol eluate, concentrating under reduced pressure, and freeze-drying to obtain the pomegranate bark extract.

The preparation method of the shampoo comprises the following steps:

(1) adding water into a reaction cylinder, adding ammonium lauryl alcohol ether sulfate, stirring and heating to 80 ℃, and completely dissolving to obtain a solution A;

(2) adding coco betaine and coco alkyl glucoside into the solution A, uniformly stirring, cooling to 75 ℃, and completely dissolving to obtain a solution B;

(3) adding the amino acid surfactant, the pomegranate peel extract and the polyquaternium-10 into the solution B, uniformly stirring, cooling to 55 ℃, adding the glycerol, uniformly stirring, and completely dissolving to obtain a solution C;

(4) cooling the solution C to 45 deg.C, adding PEG-7 olive oil, benzoic acid, salicylic acid and essence, finally adding cocamide monoethanolamine and PEG-120 methyl glucose dioleate, mixing well, and discharging.

Example 2:

an anti-dandruff shampoo with rich foam is prepared from the following raw materials in percentage by weight: 1% of ammonium lauryl alcohol ether sulfate, 4% of coco betaine, 1% of coco alkyl glucoside, 10% of amino acid surfactant, 1% of pomegranate peel extract, 2% of PEG-7 olive oil, 100.1% of polyquaternium-ammonium salt, 1% of cocamide monoethanolamine, 0.2% of PEG-120 methyl glucose dioleate, 0.05% of benzoic acid, 0.01% of salicylic acid, 5% of glycerol, 0.3% of essence and the balance of water; the amino acid surfactant is a compound of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl amino acid, and the mass ratio of the sodium lauroyl sarcosinate to the sodium myristoyl sarcosinate is 1: 3: 20.

the preparation method of the pomegranate bark extract and the preparation method of the shampoo are the same as the example 1.

Example 3:

an anti-dandruff shampoo with rich foam is prepared from the following raw materials in percentage by weight: 3% of ammonium lauryl alcohol ether sulfate, 1% of cocobetaine, 5% of cocoalkyl glucoside, 2% of amino acid surfactant, 2% of pomegranate peel extract, 1% of PEG-7 olive oil, 100.5% of polyquaternium-cocoamide monoethanolamine, 0.2% of PEG-120 methyl glucose dioleate, 0.01% of benzoic acid, 0.05% of salicylic acid, 1% of glycerol, 0.8% of essence and the balance of water; the amino acid surfactant is a compound of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl amino acid, and the mass ratio of the sodium lauroyl sarcosinate to the sodium myristoyl sarcosinate is 1: 5: 10.

the preparation method of the pomegranate bark extract and the preparation method of the shampoo are the same as the example 1.

Comparative example 1:

a shampoo is different from the shampoo of example 1 only in that the raw material components do not contain pomegranate bark extract, and the other raw material components are the same as those of example 1.

Comparative example 2:

the shampoo is characterized in that the raw material components are only different from those in example 1 in that the mass ratio of sodium lauroyl sarcosinate to sodium lauroyl glutamate to sodium myristoyl amino acid in the amino acid surfactant is 10: 3: 1, the rest is the same as example 1.

Comparative example 3:

the only difference between the raw material components of the shampoo and the raw material components of the shampoo in example 1 is that the mass ratio of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl amino acid in the amino acid surfactant is 1: 1: 1, the rest is the same as example 1.

Comparative example 4:

the only difference between the raw material components of the sunscreen spray and the raw material components of the sunscreen spray in the embodiment 1 is that the pomegranate bark extract is obtained by collecting 40% ethanol eluent in the step (4), concentrating under reduced pressure and freeze-drying, and the other steps are the same as the step (1).

First, shampoo initial foam height test

The shampoos prepared in examples 1 to 3 and comparative examples 1 to 4 were tested for initial foam height according to the method specified in "6.2.6 foam (shampoo)" in GB13173-2008 "surfactant detergent test methods", and the test results are shown in table 1.

TABLE 1

	Example 1	Example 2	Example 3	Comparative example 1	Comparative example 2	Comparative example 3	Comparative example 4
								Initial foam height/mm	158	151	143	127	118	139	135

As can be seen from the test results, the shampoos according to examples 1-3 of the present invention have excellent initial foam height, wherein example 1 is the most preferred embodiment. The experimental test data of example 1 and comparative examples 1 to 4 can be used to conclude that: according to the invention, the amino acid surfactant is obtained by compounding three raw materials of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl amino acid according to a specific proportion, and the pomegranate bark extract is added, so that an unexpected technical effect is achieved in the aspect of foam richness. Meanwhile, the pomegranate rind extract must be obtained through a specific preparation method, and satisfactory and rich foam can be obtained finally.

Second, dandruff removal Effect test

80 patients with dandruff are selected, each patient is scored by using an adhesive dandruff ten-grade scoring method, and the 80 patients are averagely divided into 4 groups of 20 patients each according to the scoring grade, so that the severity of dandruff of each group of patients has no significant difference and is comparable. The test groups 1 to 4 used the shampoos prepared in examples 1 to 3 and comparative example 4, respectively, once a day in the morning, continuously used for 7 days, not washed for 8 to 9 days, and observed the dandruff condition of the user in the afternoon of 10 days, and evaluated the complete treatment effective rate (the percentage of people who have no dandruff to the total number of the group after use), and the test results are shown in table 2 below.

TABLE 2

	Example 1	Example 2	Example 3	Comparative example 4
					The total effective rate of the treatment	90%	85%	85%	45%

From the test results, it can be concluded that the shampoos of examples 1-3 of the present invention have excellent anti-dandruff effects. The shampoo of comparative example 4 employs a pomegranate bark extract prepared by a different method from examples 1 to 3, resulting in a greatly reduced anti-dandruff effect.

The above-mentioned embodiments are merely preferred embodiments of the present invention, and the scope of the present invention should not be limited thereby, and those skilled in the art should not make any insubstantial changes and substitutions based on the present invention.

Claims (1)

1. An anti-dandruff shampoo with rich foam is prepared from the following raw materials in percentage by weight: 2% of ammonium lauryl alcohol ether sulfate, 3% of cocobetaine, 2% of cocoglucoside, 5% of amino acid surfactant, 1% of pomegranate peel extract, 2% of PEG-7 olive oil, 0.5% of polyquaternium-100.25%, 0.5% of cocamide monoethanolamine, 0.5% of PEG-120 methyl glucose dioleate, 0.03% of benzoic acid, 0.03% of salicylic acid, 3% of glycerol, 0.5% of essence and the balance of water; the amino acid surfactant is a compound of sodium lauroyl sarcosinate, sodium lauroyl glutamate and sodium myristoyl amino acid, and the mass ratio of the sodium lauroyl sarcosinate to the sodium myristoyl sarcosinate is 1: 5: 20;

the preparation method of the pomegranate bark extract comprises the following steps:

(1) weighing pulverized pericarpium Granati, adding 75% ethanol solution according to solid-to-liquid ratio g/mL of 1:30, ultrasonic-assisted extracting for 50 min, filtering, extracting the residue for 1 time, mixing filtrates, and concentrating under reduced pressure;

(2) extracting the concentrated solution twice by using equal volume of ethyl acetate, combining the extract solutions, recovering ethyl acetate to half volume, and extracting by using equal volume of sodium hydroxide solution with mass concentration of 4%;

(3) adjusting the pH value of the extract to 4 by using dilute hydrochloric acid, adding a gelatin solution with the mass concentration of 5%, standing overnight, and filtering; collecting precipitate, dissolving with 60% acetone solution, filtering off insoluble substances, and recovering acetone from filtrate;

(4) after recovering acetone from the filtrate, loading the filtrate to a pretreated polyamide chromatographic column, eluting with 20%, 40% and 60% of absolute ethanol in a volume concentration of 5 times the volume of the column in sequence, collecting the absolute ethanol eluate, concentrating under reduced pressure, and freeze-drying to obtain a pomegranate bark extract;

the preparation method of the shampoo comprises the following steps:

(1) adding water into a reaction cylinder, adding ammonium lauryl alcohol ether sulfate, stirring and heating to 80 ℃, and completely dissolving to obtain a solution A;

(2) adding coco betaine and coco glucoside into the solution A, uniformly stirring, cooling to 75 ℃, and completely dissolving to obtain a solution B;

(3) adding the amino acid surfactant, the pomegranate peel extract and the polyquaternium-10 into the solution B, uniformly stirring, cooling to 55 ℃, adding the glycerol, uniformly stirring, and completely dissolving to obtain a solution C;

(4) cooling the solution C to 45 deg.C, adding PEG-7 olive oil, benzoic acid, salicylic acid and essence, finally adding cocamide monoethanolamine and PEG-120 methyl glucose dioleate, mixing well, and discharging.