CN107412022A - A kind of preparation method of the anti-acne repair latex containing chamomile essential oil - Google Patents
A kind of preparation method of the anti-acne repair latex containing chamomile essential oil Download PDFInfo
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- CN107412022A CN107412022A CN201710761588.6A CN201710761588A CN107412022A CN 107412022 A CN107412022 A CN 107412022A CN 201710761588 A CN201710761588 A CN 201710761588A CN 107412022 A CN107412022 A CN 107412022A
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- essential oil
- chamomile essential
- acne
- oil
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- 235000007866 Chamaemelum nobile Nutrition 0.000 title claims abstract description 26
- 235000007232 Matricaria chamomilla Nutrition 0.000 title claims abstract description 26
- 239000000341 volatile oil Substances 0.000 title claims abstract description 23
- 230000003255 anti-acne Effects 0.000 title claims abstract description 15
- 239000004816 latex Substances 0.000 title claims abstract description 11
- 229920000126 latex Polymers 0.000 title claims abstract description 11
- 238000002360 preparation method Methods 0.000 title claims description 11
- 240000003538 Chamaemelum nobile Species 0.000 title abstract 4
- 239000007788 liquid Substances 0.000 claims abstract description 28
- 239000000839 emulsion Substances 0.000 claims abstract description 18
- 239000003921 oil Substances 0.000 claims abstract description 18
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 13
- 239000012071 phase Substances 0.000 claims abstract description 13
- 239000008346 aqueous phase Substances 0.000 claims abstract description 10
- 108010022355 Fibroins Proteins 0.000 claims abstract description 5
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 5
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims abstract description 5
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims abstract description 5
- 244000042664 Matricaria chamomilla Species 0.000 claims description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
- 229930003427 Vitamin E Natural products 0.000 claims description 6
- 238000000605 extraction Methods 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 6
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 6
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical class CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 6
- 239000011709 vitamin E Substances 0.000 claims description 6
- 235000019165 vitamin E Nutrition 0.000 claims description 6
- 229940046009 vitamin E Drugs 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 4
- AXPZIVKEZRHGAS-UHFFFAOYSA-N 3-benzyl-5-[(2-nitrophenoxy)methyl]oxolan-2-one Chemical compound [O-][N+](=O)C1=CC=CC=C1OCC1OC(=O)C(CC=2C=CC=CC=2)C1 AXPZIVKEZRHGAS-UHFFFAOYSA-N 0.000 claims description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 241000220317 Rosa Species 0.000 claims description 3
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 3
- 235000009754 Vitis X bourquina Nutrition 0.000 claims description 3
- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 3
- 235000014787 Vitis vinifera Nutrition 0.000 claims description 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 3
- 239000008367 deionised water Substances 0.000 claims description 3
- 229910021641 deionized water Inorganic materials 0.000 claims description 3
- 238000004821 distillation Methods 0.000 claims description 3
- 239000012153 distilled water Substances 0.000 claims description 3
- 230000001804 emulsifying effect Effects 0.000 claims description 3
- 238000001704 evaporation Methods 0.000 claims description 3
- 230000008020 evaporation Effects 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 239000011780 sodium chloride Substances 0.000 claims description 3
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 3
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 3
- 239000011718 vitamin C Substances 0.000 claims description 3
- 240000006365 Vitis vinifera Species 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract description 13
- 206010000496 acne Diseases 0.000 abstract description 13
- 230000000694 effects Effects 0.000 abstract description 12
- 230000000172 allergic effect Effects 0.000 abstract description 3
- 208000010668 atopic eczema Diseases 0.000 abstract description 3
- 230000000845 anti-microbial effect Effects 0.000 abstract description 2
- 239000002537 cosmetic Substances 0.000 abstract description 2
- 230000000249 desinfective effect Effects 0.000 abstract description 2
- 230000010354 integration Effects 0.000 abstract description 2
- 230000003020 moisturizing effect Effects 0.000 abstract description 2
- 230000037307 sensitive skin Effects 0.000 abstract description 2
- 230000002087 whitening effect Effects 0.000 abstract description 2
- 238000004945 emulsification Methods 0.000 abstract 1
- 230000002045 lasting effect Effects 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 description 10
- 210000003491 skin Anatomy 0.000 description 5
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 238000003475 lamination Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 210000002374 sebum Anatomy 0.000 description 3
- 206010040882 skin lesion Diseases 0.000 description 3
- 231100000444 skin lesion Toxicity 0.000 description 3
- 208000020154 Acnes Diseases 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 description 2
- 241000219095 Vitis Species 0.000 description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000008169 grapeseed oil Substances 0.000 description 2
- 229960001340 histamine Drugs 0.000 description 2
- 230000002757 inflammatory effect Effects 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 241000186427 Cutibacterium acnes Species 0.000 description 1
- 208000036828 Device occlusion Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- 206010033733 Papule Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- 239000003098 androgen Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000003399 chemotactic effect Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000008921 facial expression Effects 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 210000004969 inflammatory cell Anatomy 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 238000002647 laser therapy Methods 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 229940127249 oral antibiotic Drugs 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229940055019 propionibacterium acne Drugs 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229960003604 testosterone Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A kind of anti-acne repair latex containing chamomile essential oil, belongs to emulsion preparing technical field, the present invention includes：Chamomile essential oil is prepared, aqueous phase liquid is prepared, prepares oil phase feed liquid and emulsification.The emulsion addition chamomile essential oil and grape-kernel oil of the present invention, has disinfecting, antimicrobial, sensitive skin of releiving, lasting the effect of protecting skin not disturbed by whelk acne.Fibroin has the effect of repairing skin tissue's cell.Using sodium carboxymethylcellulose as emulsifying agent, the hydrosol, emulsifying agent, thickener are mainly used as in cosmetics, extract effective integration can be given full play to skin care effect together.Emulsion produced by the present invention is added without chemistry, and with excellent anti-acne, moisturizing, whitening and skin-protecting effect, long-term use can make skin smooth bright, and be applied to easy allergic person.
Description
Technical field
The present invention relates to emulsion preparing technical field, and in particular to a kind of system of the anti-acne repair latex containing chamomile essential oil
Preparation Method.
Background technology
Acne is a kind of chronic inflammatory skin of pilosebaceous unit, teenager is mainly apt to occur in, to teenager
Psychology and social influence it is very big.Clinical manifestation using be apt to occur in the acne of face, papule, warts, the polymorphy skin lesion such as tubercle as
Feature, nickname acne, whelk.The generation of acne mainly blocks with hypersteatosis, pilosebaceous duct, bacterium infection
It is closely related with the factor such as inflammatory reaction.Adolesce the rapid rise of level of androgen particularly testosterone in descendant's body, promotees
Enter sebaceous glands to develop and produce a large amount of sebums.The dyskeratosis of pilosebaceous duct causes catheter blockage, sebum discharge simultaneously
Obstacle, it is micro mist thorn to form horn plug.Multiple-microorganism especially propionibacterium acnes amount reproduction in hair follicle, acne propionic acid bar
Lipase caused by bacterium decomposes sebum generation free fatty, while chemotactic inflammatory cell and medium, finally induces and aggravates inflammation
Reaction.
The method for the treatment of acne has at present：Oral antibiotic/vitamin/glucocorticoid/sex hormone zinc preparation and external application
Drug therapy, the therapy such as injection treatment/laser ultraviolet in skin lesion.Although these methods also have certain effect, have
The drawbacks of certain, such as the side effect such as endo-medicine overlong time, antibiotic/hormone, injection treatment/laser ultraviolet in skin lesion
Compare pain etc. therapy, laser therapy easily forms the charring layer of black, disturbs surgical field of view, patient is not easy observation and grasps treatment
The depth reached.The result of control treatment is difficult to if if over the course for the treatment of, assurance is not in place.
For this phenomenon we in addition to hospital can be gone to use the treatment method such as medicine/laser, contained using some
The emulsion of anti-acne composition also has good therapeutic effect, so as to develop the emulsion of the present invention.
The content of the invention
In order to solve problems of the prior art, the present invention provides a kind of anti-acne repair latex containing chamomile essential oil
Preparation method.
The present invention uses following technical scheme：
A kind of preparation method of the anti-acne repair latex containing chamomile essential oil, comprises the following steps：
Step 1：200g chamomiles dried flower is weighed with distilled water with 1:8 solid-liquid ratio mixing, obtains distillate, is placed in
In 5000ml container, and into distillate add mass percent 1% sodium chloride, stand 4 hours；
Step 2：Distillate is heated with electric jacket, keeps slight boiling condition to be extracted, and distillation 3 hours of extraction, stops adding
Heat, filter to get filtrate；
Step 3：Take filtrate 0.5ml, add the extraction of 20ml hexanes, stand overnight, with Rotary Evaporators heating evaporation,
Obtain yellow transparent shape chamomile essential oil；
Step 4：Deionized water is weighed, is heated to 60 DEG C, adds the carboxylic benzyl for accounting for ionized water mass percent 1%,
Whole dissolvings are treated, add the Sodium Hyaluronate for accounting for ionized water mass percent 2%, is well mixed and is cooled to room temperature, then
The glycerine and 3% 1,3-BDO for accounting for ionized water mass percent 6% are added, is well mixed, is added and account for ionized water
The fibroin of mass percent 5% and 1% L-vitamin C mixing hook, and obtain aqueous phase liquid；
Step 5：Chamomile essential oil and grape-kernel oil are taken, and adds vitamin E and emulsifying agent, wherein chamomile essential oil, Portugal
Grape seed oil, vitamin E, the mass ratio of emulsifying agent are 50:50:1:3, it is well mixed to obtain oil phase feed liquid；
Step 6：Aqueous phase liquid is slowly added into oil phase feed liquid, described aqueous phase liquid and oil phase feed liquid mass ratio
For 85:15, mixed liquor is well mixed to obtain, the sodium carboxymethylcellulose of percentage by weight 3% is added into mixed liquor, then will mixing
Liquid adds vacuum emulsifying machine Inner and emulsified, and produces emulsion.
Preferably, the emulsifying agent in described step five is polyvinyl alcohol.
Preferably, the essence that percentage by weight 3% is added into oil phase feed liquid is also included in described step five.
Preferably, described essence is flavoring rose essence.
The beneficial effects of the present invention are:
1) chamomile essential oil has disinfecting, antimicrobial, sensitive skin of releiving, and persistently protects skin not disturbed by whelk acne
The effect of.
2) OPC (OPC) is that the main composition of grape pip has the superpower anti-oxidant ability for removing free radical,
The harmful substances such as free radical can be removed rapidly, the release of inflammatory factor is fundamentally prevented, so as to remove this inflammation disease of acne
Shape, suppress allergic phenomena.Grape pip can suppress to produce the enzyme that histamine needs, and prevent from generating histamine, so as to dephlogistication symptom, have
Effect goes acne.
3) fibroin has the effect of repairing skin tissue's cell.
4) hydrosol, emulsifying agent, thickening are mainly used as in cosmetics as emulsifying agent using sodium carboxymethylcellulose
Agent, extract effective integration can be given full play to skin care effect together.
5) emulsion produced by the present invention is added without chemistry, and has excellent anti-acne, moisturizing, whitening and skin-protecting effect, for a long time
Using that can make, skin smooth is bright, and is applied to easy allergic person.
Embodiment
Below with reference to specific embodiment, the present invention is described further.
Embodiment 1
A kind of preparation method of the anti-acne repair latex containing chamomile essential oil, comprises the following steps：
Step 1：200g chamomiles dried flower is weighed with distilled water with 1:8 solid-liquid ratio mixing, obtains distillate, is placed in
In 5000ml container, and into distillate add mass percent 1% sodium chloride, stand 4 hours；
Step 2：Distillate is heated with electric jacket, keeps slight boiling condition to be extracted, and distillation 3 hours of extraction, stops adding
Heat, filter to get filtrate；
Step 3：Take filtrate 0.5ml, add the extraction of 20ml hexanes, stand overnight, with Rotary Evaporators heating evaporation,
Obtain yellow transparent shape chamomile essential oil；
Step 4：Deionized water is weighed, is heated to 60 DEG C, adds the carboxylic benzyl for accounting for ionized water mass percent 1%,
Whole dissolvings are treated, add the Sodium Hyaluronate for accounting for ionized water mass percent 2%, is well mixed and is cooled to room temperature, then
The glycerine and 3% 1,3-BDO for accounting for ionized water mass percent 6% are added, is well mixed, is added and account for ionized water
The fibroin of mass percent 5% and 1% L-vitamin C mixing hook, and obtain aqueous phase liquid；
Step 5：Chamomile essential oil and grape-kernel oil are taken, and adds vitamin E and emulsifying agent, wherein chamomile essential oil, Portugal
Grape seed oil, vitamin E, the mass ratio of emulsifying agent are 50:50:1:3, it is well mixed to obtain oil phase feed liquid；
Step 6：Aqueous phase liquid is slowly added into oil phase feed liquid, described aqueous phase liquid and oil phase feed liquid mass ratio
For 85:15, mixed liquor is well mixed to obtain, the sodium carboxymethylcellulose of percentage by weight 3% is added into mixed liquor, then will mixing
Liquid adds vacuum emulsifying machine Inner and emulsified, and produces emulsion.
Emulsifying agent in described step five is polyvinyl alcohol.
Also include the essence that percentage by weight 3% is added into oil phase feed liquid in described step five, described essence is
Flavoring rose essence.
The physical and chemical index of embodiment 1 is as follows：
(1) character
This product is that viscosity is suitable, fine and smooth uniform, the good emulsion of stretchability.
(2) pH value inspection
A small amount of emulsion, pH 6-7 are dipped with the pH test paper of wetting.
(3) caloric test
Emulsion is packaged in clear vial, in 4 DEG C of refrigerator cold-storage observations in one week or so without lamination.In 55 DEG C of perseverance
24h in incubator, no phenomena such as being layered, be spoiled.
(4) centrifugal test
Emulsion is packaged in 3000r/min in tool plug test tube and centrifuges 20min, no lamination.
(5) irritation test, sensitivity test
Small white mouse back cuts off hair, smears by emulsion prepared by embodiment 1 in cutting plucked position, and do not apply position and carry out
Compare, as a result without excitant and allergic reaction.
Emulsion prepared by Example 1 is applied in volunteer's gesture and facial expression, is observed after spending 30 minutes, does not occur rubescent, dermexanthesis,
Foaming phenomena.
(6) room temperature places experiment
The made emulsion of embodiment 1 is placed in bottle, investigation 6 months is stored at room temperature, no lamination, feels after without change
Change, smell is unchanged.
(7) anti-acne effect
The serious people of volunteer 15 of face acnes is chosen, the emulsion of the gained of embodiment 1 is used for volunteer's face acnes disease
At shape, volunteer is generally comfortable on, and acne lightens, and does not stay acne print.Continuous use through a period of time, the situation of acne are obvious
Improve and even disappear.
Claims (4)
1. a kind of preparation method of the anti-acne repair latex containing chamomile essential oil, it is characterised in that comprise the following steps：
Step 1：200g chamomiles dried flower is weighed with distilled water with 1:8 solid-liquid ratio mixing, obtains distillate, is placed in 5000ml's
In container, and into distillate add mass percent 1% sodium chloride, stand 4 hours；
Step 2：Distillate is heated with electric jacket, keeps slight boiling condition to be extracted, and distillation 3 hours of extraction, stops heating,
Filter to get filtrate；
Step 3：Filtrate 0.5ml is taken, the extraction of 20ml hexanes is added, stands overnight, with Rotary Evaporators heating evaporation, obtain
Yellow transparent shape chamomile essential oil；
Step 4：Deionized water is weighed, is heated to 60 DEG C, adds the carboxylic benzyl for accounting for ionized water mass percent 1%, is treated complete
Portion dissolves, and adds the Sodium Hyaluronate for accounting for ionized water mass percent 2%, is well mixed and is cooled to room temperature, adds
The glycerine of ionized water mass percent 6% and 3% 1,3-BDO are accounted for, is well mixed, is added and account for ion water quality
The fibroin of percentage 5% and 1% L-vitamin C mixing hook, and obtain aqueous phase liquid；
Step 5：Chamomile essential oil and grape-kernel oil are taken, and adds vitamin E and emulsifying agent, wherein chamomile essential oil, grape pip
Oil, vitamin E, the mass ratio of emulsifying agent are 50:50:1:3, it is well mixed to obtain oil phase feed liquid；
Step 6：Aqueous phase liquid is slowly added into oil phase feed liquid, described aqueous phase liquid is 85 with oil phase feed liquid mass ratio:
15, mixed liquor is well mixed to obtain, the sodium carboxymethylcellulose of percentage by weight 3% is added into mixed liquor, then mixed liquor is added
Enter vacuum emulsifying machine Inner to be emulsified, produce emulsion.
A kind of 2. preparation method of anti-acne repair latex containing chamomile essential oil according to claim 1, it is characterised in that：
Emulsifying agent in described step five is polyvinyl alcohol.
A kind of 3. preparation method of anti-acne repair latex containing chamomile essential oil according to claim 1, it is characterised in that：
Also include the essence that percentage by weight 3% is added into oil phase feed liquid in described step five.
A kind of 4. preparation method of anti-acne repair latex containing chamomile essential oil according to claim 3, it is characterised in that：
Described essence is flavoring rose essence.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710761588.6A CN107412022A (en) | 2017-08-30 | 2017-08-30 | A kind of preparation method of the anti-acne repair latex containing chamomile essential oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710761588.6A CN107412022A (en) | 2017-08-30 | 2017-08-30 | A kind of preparation method of the anti-acne repair latex containing chamomile essential oil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107412022A true CN107412022A (en) | 2017-12-01 |
Family
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103705423A (en) * | 2013-12-26 | 2014-04-09 | 青岛永通电梯工程有限公司 | Acne-removing compound essential oil |
| CN105176689A (en) * | 2015-07-17 | 2015-12-23 | 王再青 | Method for improving extraction rate of chamomilia essential oil |
| CN105250606A (en) * | 2015-10-09 | 2016-01-20 | 广州萃纳康生物科技有限公司 | Natural plant acne removing agent |
| CN105560122A (en) * | 2016-01-22 | 2016-05-11 | 柳州博泽科技有限公司 | Pure natural facial cleanser with oil controlling and acne removing functions and preparing method thereof |
| CN106350220A (en) * | 2016-08-26 | 2017-01-25 | 广西灏源盛世生物科技有限公司 | Method for extracting essential oil from chamomile |
| CN106821940A (en) * | 2017-03-27 | 2017-06-13 | 上海莱妃化妆品有限公司 | A kind of formula for dispelling pox |
| CN107095820A (en) * | 2017-06-06 | 2017-08-29 | 安徽吉乃尔电器科技有限公司 | A kind of preparation method of saururus chinensis whitening emulsion |
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- 2017-08-30 CN CN201710761588.6A patent/CN107412022A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705423A (en) * | 2013-12-26 | 2014-04-09 | 青岛永通电梯工程有限公司 | Acne-removing compound essential oil |
| CN105176689A (en) * | 2015-07-17 | 2015-12-23 | 王再青 | Method for improving extraction rate of chamomilia essential oil |
| CN105250606A (en) * | 2015-10-09 | 2016-01-20 | 广州萃纳康生物科技有限公司 | Natural plant acne removing agent |
| CN105560122A (en) * | 2016-01-22 | 2016-05-11 | 柳州博泽科技有限公司 | Pure natural facial cleanser with oil controlling and acne removing functions and preparing method thereof |
| CN106350220A (en) * | 2016-08-26 | 2017-01-25 | 广西灏源盛世生物科技有限公司 | Method for extracting essential oil from chamomile |
| CN106821940A (en) * | 2017-03-27 | 2017-06-13 | 上海莱妃化妆品有限公司 | A kind of formula for dispelling pox |
| CN107095820A (en) * | 2017-06-06 | 2017-08-29 | 安徽吉乃尔电器科技有限公司 | A kind of preparation method of saururus chinensis whitening emulsion |
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