CN105727382B - A kind of continous way CRRT machine capability bascules of two tripper - Google Patents

Abstract

A continuous CRRT machine capacity balance device with two circuit breakers, including a blood circulation system composed of an inlet line, a blood pump, a hollow fiber dialyzer, and a return line; The first liquid circulation system consists of liquid container, hollow fiber dialyzer, and return line, and there are two replacement fluid/dialysis fluid containers. Increased by exogenous replacement fluid/dialysis fluid container, exogenous replacement fluid/dialysis fluid container outlet pipeline, circuit breaker, liquid pump, replacement fluid/dialysis fluid container, exogenous replacement fluid/dialysis fluid container return liquid The second liquid circulation system composed of pipelines. The first liquid circulation system is in contact with the blood circulation system for substance exchange, and since its volume is fixed, no volume change is involved in the exchange process. The second liquid circulation system performs liquid exchange on the two liquid replacement/dialysis fluid containers in turn, so that they are filled with clean fresh replacement fluid, so as to achieve the purpose of continuously removing solutes in a mobile environment.

Description

A continuous CRRT machine capacity balance device with two breakers

technical field

The invention belongs to a continuous blood purification device, in particular to a continuous CRRT machine capacity balance device with two circuit breakers.

Background technique

CRRT (that is, continuous renal replacement therapy) English abbreviation for continuous renal replacement therapy. Also known as CBP (continuous blood purification); bedside blood filtration. It is a long-term, continuous extracorporeal blood purification therapy used 24 hours a day or close to 24 hours to replace damaged kidney function.

In 1995, at the first international CRRT academic conference held in San Diego, USA, CRRT was officially defined as: all blood purification technologies that can continuously remove solutes and support organ functions. During the Second World War, Murray and Delmore in Canada successfully developed the first artificial kidney machine, which was used in clinical treatment of renal failure in 1946, after which blood purification technology developed rapidly. Blood purification is to lead the patient's blood out of the body and pass through a purification device to remove some pathogenic substances and purify the blood to treat diseases. It mainly includes hemodialysis, hemofiltration, hemodiafiltration, hemoperfusion, plasma exchange, immunoadsorption, etc. At present, blood purification therapy is not only used to treat acute and chronic renal failure patients, but also has been widely used in the emergency treatment of critically ill patients.

The clinical application goals of CRRT are to remove excess water in the body, remove metabolic wastes and poisons in the body, correct water and electrolyte disorders, ensure nutritional support, promote the recovery of renal function, and remove various cytokines and inflammatory mediators. It can be used for: acute and chronic renal failure with unstable cardiovascular function, hypercatabolism or cerebral edema, as well as multiple organ dysfunction syndrome, acute respiratory distress syndrome, crush syndrome, acute necrotizing pancreas Inflammation, chronic heart failure, hepatic encephalopathy, drug and poison poisoning, etc.

At present, the CRRT machines produced by the Braun company of Germany, the CRRT machines produced by the German Fresenius Group, or some other brands of CRRT machines are mostly used clinically for continuous renal replacement therapy.

During the working process of the CRRT machine, it is necessary to precisely control the speed and volume of fluid entering and exiting the patient's extracorporeal circulation. The difference between the volume of fluid entering and exiting is the net ultrafiltration, that is, the water removed from the body. Usually, the CRRT machine uses the replacement fluid/dialysate pump to control the speed of the fluid entering the extracorporeal circulation, and the waste pump to control the speed of the fluid exiting the extracorporeal circulation. At the same time, the scale inside the CRRT machine is used to accurately and dynamically measure the amount of fluid entering and leaving the body, and Feedback adjustment of replacement fluid/dialysis fluid, waste pump speed to achieve the purpose of controlling the amount of fluid in and out of the extracorporeal circulation.

Obviously, there are drawbacks in controlling the balance of liquid in and out by dynamically measuring the weight of the liquid with a scale: first, the scale needs to be calibrated frequently, and the accuracy will gradually decrease during use; The impact of the scale will make the scale inoperable, so the existing CRRT machines cannot work in the mobile environment.

In order to overcome the shortcomings of weighing with a scale and not being able to use CRRT machines in a mobile environment, some people have studied the method of flow monitoring to realize the capacity control of CRRT machines, that is, dynamically measure the flow rate of inflow and outflow extracorporeal circulation fluid and calculate the flow rate according to the cross-sectional area . The methods for dynamic measurement of flow velocity include magnetic current method and ultrasonic method. Although this method can avoid the defect that the scale cannot work under moving conditions, it still has the defects of insufficient precision and large errors. Instant flow measurement needs to measure the flow once in a few seconds, and it needs to measure dozens of times within a minute, and then add up the results of each measurement to obtain the amount of liquid per unit time. Therefore, even if the error of a single measurement is small, the cumulative effect of the errors of countless measurement results will inevitably lead to a large total error. Compared with instant flow measurement, although the scale system also measures dynamically, it directly measures the total liquid in and out in a certain period of time each time, rather than through the accumulation of multiple measurement results, so there is no cumulative effect. In addition, tiny air bubbles in the liquid and changes in the cross-sectional area of the pipeline during use will affect the flow measurement accuracy.

For CRRT treatment, the daily fluid exchange volume is generally more than 20L, and the maximum can be more than 100L. If the error is within 1%, the fluid error volume is 200ml-1000ml. If the treatment lasts for several days, the absolute error volume is even greater. However, the flowmeter control capacity balance error is difficult to reach below 1%.

Existing CRRT machines are not suitable for CRRT treatment in mobile vehicles such as airplanes, cars, trains, and ships, which brings challenges to the urgent need for CRRT treatment, but due to distance and transportation restrictions, CRRT treatment cannot be performed. For example, soldiers injured on the battlefield can only be transported back to the medical base for rescue and treatment, and critically ill patients cannot be rescued and treated in an ambulance.

Therefore, CRRT machines need more convenient and accurate capacity control devices and systems.

Contents of the invention

In order to solve the above-mentioned technical problems, the present invention proposes a continuous CRRT machine capacity balance device with two circuit breakers, including a blood circulation system composed of an inlet blood vessel, a blood pump, a hollow fiber dialyzer, and a return blood vessel. The first liquid circulation system consisting of a circuit, a liquid pump, a replacement fluid/dialysate container, a hollow fiber dialyzer, and a liquid return line.

The blood circulation system and the first fluid circulation system use a common hollow fiber dialyzer, and the blood in the blood circulation system and the replacement fluid/dialysis fluid in the first fluid circulation system perform solute exchange through the common hollow fiber dialyzer.

Hollow fiber dialyzer includes blood inlet, blood outlet, replacement fluid/dialysis fluid outlet, replacement fluid/dialysis fluid inlet, replacement fluid/dialysis fluid outlet, replacement fluid/dialysis fluid inlet are collectively referred to as hollow fiber dialyzer fluid ports. ;

After one end of the blood inlet line is introduced into the blood vessel of the patient, the other end is connected to the blood inlet of the hollow fiber dialyzer through the blood pump, and one end of the blood return line is connected to the blood outlet of the hollow fiber dialyzer, and the other end returns the blood to the patient in vivo.

There are two replacement fluid/dialysis fluid containers in the first liquid circulation system, which are the first replacement fluid/dialysis fluid container and the second replacement fluid/dialysis fluid container.

One end of the outlet pipeline is connected to the liquid port of the hollow fiber dialyzer, and after passing through the liquid pump, it is divided into two paths, one path passes through the first circuit breaker and is connected to the first replacement fluid/dialysate container, and the other path passes through the second circuit breaker and then connected to the first replacement fluid/dialysis fluid container. Connect the second replacement fluid/dialysis fluid container.

One end of the liquid return line is connected to the liquid port of the hollow fiber dialyzer or the blood inlet line, and the other end is divided into two lines, one line passes through the first circuit breaker and then connects to the first replacement fluid/dialysate container, and the other line passes through the second circuit breaker A second replacement/dialysate container is connected to the rear of the device.

Also includes exogenous replacement fluid/dialysis fluid container, exogenous replacement fluid/dialysis fluid container outlet line, liquid pump, circuit breaker, replacement fluid/dialysis fluid container, exogenous replacement fluid/dialysis fluid container return The second liquid circulation system composed of liquid pipelines.

One end of the outlet line of the exogenous replacement fluid/dialysis fluid container is connected to the exogenous replacement fluid/dialysis fluid container, and the other end is divided into two paths after passing through the liquid pump, and one end is connected to the second replacement fluid after passing through the first circuit breaker. / dialysate container, and the other way is connected to the first replacement fluid/dialysate container after passing through the second circuit breaker.

One end of the exogenous replacement fluid/dialysis fluid container return line is connected to the exogenous replacement fluid/dialysis fluid container, and the other end is divided into two paths, one of which passes through the first circuit breaker and then connected to the second replacement fluid/dialysis fluid container , and the other path is connected to the first replacement fluid/dialysis fluid container after passing through the second circuit breaker.

The first circuit breaking device and the second circuit breaking device are controlled in linkage, when the first circuit breaking device is opened, the second circuit breaking device is automatically closed, and when the first circuit breaking device is closed, the second circuit breaking device is automatically opened.

An ultrafiltration system composed of an ultrafiltration pipeline, an ultrafiltration pump and an ultrafiltration container is also arranged at the front end of the liquid outlet pipeline.

The ultrafiltration system also includes a flow monitoring device installed on the ultrafiltration pipeline to monitor the liquid velocity and flow in the ultrafiltration pipeline.

The first circuit breaking device and the second circuit breaking device are pipe clips.

The replacement fluid/dialysis fluid container can also be two cavities isolated from each other on the same device.

The first circuit breaking device can also be a group of circuit breaking devices, and each circuit breaking device is connected to the outlet pipeline, the liquid return pipeline, the outlet pipeline of the exogenous replacement fluid/dialysate container, and the outlet pipeline of the exogenous replacement fluid/dialysis fluid. Linkage control of container return line;

The second circuit breaking device can also be a group of circuit breaking devices, and each circuit breaking device is connected to the outlet pipeline, the liquid return pipeline, the outlet pipeline of the exogenous replacement fluid/dialysate container, and the outlet pipeline of the exogenous replacement fluid/dialysis fluid. The container return line is controlled in linkage.

The exchange volume of the first liquid circulation system is 100-500ml.

The first circuit breaking device and the second circuit breaking device are provided with fault alarms.

A flow rate detection device is also provided on the liquid outlet pipeline or the liquid return pipeline.

There may also be more than two replacement fluid/dialysis fluid containers in the first liquid circulation system.

Beneficial effect:

The continuous CRRT machine capacity balance device of the two circuit breakers of the present invention uses a closed volume fixed liquid system for solute exchange to ensure no change in capacity. When the exchange liquid reaches saturation or is close to saturation, it is regenerated by exogenous replacement fluid/dialysate , to ensure continuous solute removal capability, effectively solving the problem that existing CRRT machines cannot be used in mobile environments. At the same time, the present invention designs two replacement fluid/dialysis fluid containers, when the first replacement fluid/dialysis fluid container is connected to the first liquid circulation system for treatment, the second replacement fluid/dialysis fluid container is connected to the second liquid circulation system for exchange and regeneration; when the second replacement fluid/dialysis fluid container is connected to the first liquid circulation system for treatment, the first replacement fluid/dialysis fluid container is connected to the second fluid circulation system for exchange and regeneration; thereby realizing continuity in a mobile environment mobile therapy.

The continuous CRRT machine capacity balance device with two circuit breakers of the present invention can be widely used in continuous arteriovenous hemofiltration (CAVH), continuous venous-venous hemofiltration (CVVH), continuous slow ultrafiltration (SCUF), continuous Arteriovenous hemodialysis (CAVHD), continuous venovenous hemodialysis (CVVHD), continuous arteriovenous hemodiafiltration (CAVHDF), continuous venovenous hemodiafiltration (CVVHDF).

Description of drawings

Figure 1 is a schematic diagram of the structure of the post-dilution filtration mode of the continuous CRRT machine capacity balance device;

Fig. 2 is a schematic diagram of the structure of a continuous CRRT machine capacity balance device with a diluted filtration mode after ultrafiltration;

Fig. 3 is a schematic structural diagram of the dilution filtration mode before the continuous CRRT machine capacity balance device;

Fig. 4 is a schematic structural diagram of a continuous CRRT machine capacity balance device with a diluted filtration mode before ultrafiltration;

Fig. 5 is a schematic structural diagram of the dialysis mode of the continuous CRRT machine capacity balance device;

Fig. 6 is a schematic structural diagram of a continuous CRRT machine capacity balance device with an ultrafiltration dialysis mode;

Fig. 7 is a structural schematic diagram of a hollow fiber dialyzer;

Among them: blood inlet line 1, blood pump 2, hollow fiber dialyzer 3, blood return line 4, liquid outlet line 5, liquid pump 6, replacement fluid/dialysate container 7, return line 8, blood inlet 9- 1. Blood outlet 9-2, replacement fluid/dialysis fluid outlet 10, replacement fluid/dialysis fluid inlet 11, first circuit breaking device 12-1, second circuit breaking device 12-2, exogenous replacement fluid/dialysis fluid container 13 , Exogenous replacement fluid/dialysate container outlet pipeline 14,

Exogenous replacement fluid/dialysate container return line 15 , ultrafiltration line 16 , ultrafiltration pump 17 , ultrafiltration container 18 .

detailed description

Embodiment 1: As shown in Figures 1-7, a continuous CRRT machine capacity balance device with two circuit breakers, including a blood vessel composed of an inlet line 1, a blood pump 2, a hollow fiber dialyzer 3, and a blood return line 4 Circulation system, a first liquid circulation system composed of a liquid outlet pipeline 5, a liquid pump 6, a replacement fluid/dialysate container 7, a hollow fiber dialyzer 3, and a liquid return pipeline 8;

The blood circulation system and the first liquid circulation system use a common hollow fiber dialyzer 3, and the blood in the blood circulation system and the replacement fluid/dialysis fluid in the first liquid circulation system perform solute exchange through the common hollow fiber dialyzer 3;

The hollow fiber dialyzer 3 includes a blood inlet 9-1, a blood outlet 9-2, a replacement fluid/dialysis fluid outlet 10, a replacement fluid/dialysis fluid inlet 11, a replacement fluid/dialysis fluid outlet 10, and a replacement fluid/dialysis fluid inlet 11. is the liquid port of the hollow fiber dialyzer;

After one end of the blood inlet line 1 is introduced into the blood vessel of the patient, the blood pump 2 is connected to the blood inlet 9-1 of the hollow fiber dialyzer 3 through the other end, and one end of the blood return line 4 is connected to the blood outlet of the hollow fiber dialyzer 3 9-2, the other end returns the blood to the patient;

There are two replacement fluid/dialysis fluid containers 7 in the first liquid circulation system, which are the first replacement fluid/dialysis fluid container 7-1 and the second replacement fluid/dialysis fluid container 7-2;

One end of the liquid outlet pipeline 5 is connected to the liquid port of the hollow fiber dialyzer, and the other end is divided into two paths after passing through the liquid pump 6, and one path is connected to the first replacement fluid/dialysis fluid container 7- after passing through the first circuit breaker 12-1 1. The other path passes through the second circuit breaker 12-2 and then connects to the second replacement fluid/dialysate container 7-2;

One end of the liquid return line 8 is connected to the liquid port of the hollow fiber dialyzer or the blood inlet line 1, and the other end is divided into two paths, one path passes through the first circuit breaking device 12-1 and then connects to the first replacement fluid/dialysis fluid container 7- 1. The other path passes through the second circuit breaker 12-2 and then connects to the second replacement fluid/dialysate container 7-2;

Also includes exogenous replacement fluid/dialysis fluid container 13, exogenous replacement fluid/dialysis fluid container outlet pipeline 14, liquid pump 6, circuit breaker 12-1, 12-2, replacement fluid/dialysis fluid container 7 , The second liquid circulation system composed of the return line 15 of the exogenous replacement fluid/dialysate container;

One end of the exogenous replacement fluid/dialysis fluid container outlet pipeline 14 is connected to the exogenous replacement fluid/dialysis fluid container 13, and the other end is divided into two paths after passing through the liquid pump 6, and one path passes through the first circuit breaker 12-1 Then connect the second replacement fluid/dialysis fluid container 7-2, and the other way passes through the second circuit breaker 12-2 and then connect the first replacement fluid/dialysis fluid container 7-1;

One end of the exogenous replacement fluid/dialysis fluid container return line 15 is connected to the exogenous replacement fluid/dialysis fluid container 13, and the other end is divided into two circuits, one of which passes through the first circuit breaker 12-1 and then connected to the second replacement circuit. Liquid/dialysate container 7-2, and the other path passes through the second circuit breaker 12-2 and connects to the first replacement fluid/dialysate container 7-1;

The first circuit breaking device 12-1 and the second circuit breaking device 12-2 are linked control, when the first circuit breaking device 12-1 is opened, the second circuit breaking device 12-2 is automatically closed, when the first circuit breaking device 12-1 When closed, the second circuit breaker 12-2 is automatically opened.

An ultrafiltration system composed of an ultrafiltration pipeline 16 , an ultrafiltration pump 17 and an ultrafiltration container 18 is also provided at the front end of the outlet pipeline 5 .

The ultrafiltration system also includes a flow monitoring device, which is installed on the ultrafiltration pipeline 16 to monitor the flow rate and flow rate of the liquid in the ultrafiltration pipeline 16 .

The first circuit breaking device 12-1 and the second circuit breaking device 12-2 are pipeline clips.

The replacement fluid/dialysis fluid container 7 can also be two cavities isolated from each other on the same device.

The first circuit breaker 12-1 can also be a circuit breaker group consisting of a single or multiple circuit breakers, each circuit breaker is connected to the liquid outlet pipeline 5, the liquid return pipeline 8, the exogenous replacement fluid/dialysate, etc. The container outlet line 14 and the exogenous replacement fluid/dialysate container return line 15 are linked to control;

The second circuit breaker 12-2 can also be a circuit breaker group composed of single or multiple circuit breakers, and each circuit breaker is connected to the liquid outlet pipeline 5, the liquid return pipeline 8, and the exogenous replacement fluid/dialysate container respectively. The outlet line 14 and the return line 15 of the exogenous replacement fluid/dialysate container are linked and controlled.

The exchange volume of the first liquid circulation system is 100-500ml.

The first circuit breaker 12-1 and the second circuit breaker 12-2 are provided with fault alarms.

The liquid outlet pipeline 5 or the liquid return pipeline 8 is also provided with a flow rate detection device.

There may also be more than two replacement fluid/dialysis fluid containers 7 in the first liquid circulation system.

Embodiment 2: As shown in Figures 1, 2, and 7, it is a post-dilution filtration mode structure. When it is a filtration mode, the replacement fluid/dialysis fluid container is usually called a replacement fluid container; exogenous replacement fluid/dialysis fluid The container is usually called the exogenous replacement fluid container. The replacement fluid and the dialysate are the same liquid, and the container containing the liquid is also the same container. If the name of each component of the container involves the words "replacement" and "dialysis", different names of "replacement" and "dialysis" should be selected according to the different treatment modes.

A continuous CRRT machine capacity balance device with two circuit breakers, including a blood circulation system composed of an inlet line 1, a blood pump 2, a hollow fiber dialyzer 3, and a return line 4, and a liquid outlet line 5, a liquid pump 6. The first liquid circulation system composed of the replacement fluid container 7, the hollow fiber dialyzer 3, and the liquid return line 8;

The blood circulation system and the first liquid circulation system use a common hollow fiber dialyzer 3, and the blood in the blood circulation system and the replacement fluid in the first liquid circulation system perform solute exchange through the common hollow fiber dialyzer 3;

The hollow fiber dialyzer 3 includes a blood inlet 9-1, a blood outlet 9-2, a replacement fluid outlet 10, a replacement fluid inlet 11, and the replacement fluid outlet 10 and the replacement fluid inlet 11 are collectively referred to as the liquid port of the hollow fiber dialyzer;

After one end of the blood inlet line 1 is introduced into the blood vessel of the patient, the blood pump 2 is connected to the blood inlet 9-1 of the hollow fiber dialyzer 3 through the other end, and one end of the blood return line 4 is connected to the blood outlet of the hollow fiber dialyzer 3 9-2, the other end returns the blood to the patient;

There are two replacement fluid containers 7 in the first liquid circulation system, which are the first replacement fluid container 7-1 and the second replacement fluid container 7-2;

One end of the liquid outlet pipeline 5 is connected to the replacement fluid outlet 10 of the hollow fiber dialyzer 3, and the other end is divided into two paths after passing through the liquid pump 6, and one path is connected to the first replacement fluid container 7 after passing through the first circuit breaker 12-1. -1, the other path passes through the second circuit breaker 12-2 and then connects to the second replacement fluid container 7-2;

One end of the outlet pipeline 5 can be connected to the replacement fluid outlet 10 of the hollow fiber dialyzer 3, and can also be connected to the replacement fluid inlet 11; if one end of the outlet pipeline 5 is connected to the replacement fluid outlet of the hollow fiber dialyzer 3 10, the replacement fluid inlet 11 of the hollow fiber dialyzer 3 is sealed; if one end of the outlet pipeline 5 is connected to the replacement fluid inlet 11 of the hollow fiber dialyzer 3, the replacement fluid outlet 10 of the hollow fiber dialyzer 3 is sealed;

One end of the liquid return line 8 is connected to the blood vessel line 1, and the other end is divided into two paths, one path passes through the first circuit breaking device 12-1 and then connects to the first replacement fluid container 7-1, and the other path passes through the second circuit breaking device 12 After -2, connect the second replacement fluid container 7-2;

It also includes the exogenous replacement fluid container 13, the exogenous replacement fluid container outlet pipeline 14, the liquid pump 6, the circuit breaker 12-1, 12-2, the replacement fluid container 7, and the return liquid of the exogenous replacement fluid container. The second liquid circulation system that pipeline 15 forms;

One end of the outlet pipeline 14 of the exogenous replacement liquid container is connected to the exogenous replacement liquid container 13, and the other end is divided into two paths after passing through the liquid pump 6, and one end is connected to the second replacement liquid after passing through the first circuit breaker 12-1. Container 7-2, the other path passes through the second circuit breaker 12-2 and then connects to the first replacement fluid container 7-1;

One end of the exogenous replacement liquid container return line 15 is connected to the exogenous replacement liquid container 13, and the other end is divided into two paths, one of which passes through the first circuit breaking device 12-1 and then connects to the second replacement liquid container 7-2. The other path passes through the second circuit breaker 12-2 and then connects to the first replacement fluid container 7-1;

The first circuit breaking device 12-1 and the second circuit breaking device 12-2 are linked control, when the first circuit breaking device 12-1 is opened, the second circuit breaking device 12-2 is automatically closed, when the first circuit breaking device 12-1 When closed, the second circuit breaker 12-2 is automatically opened.

As shown in FIG. 2 , an ultrafiltration system composed of an ultrafiltration pipeline 16 , an ultrafiltration pump 17 and an ultrafiltration container 18 is also provided at the front end of the liquid outlet pipeline 5 .

The ultrafiltration system also includes a flow monitoring device, which is installed on the ultrafiltration pipeline 16 to monitor the flow rate and flow rate of the liquid in the ultrafiltration pipeline 16 .

The first circuit breaking device 12-1 and the second circuit breaking device 12-2 are pipeline clips.

The replacement fluid container 7 can also be two cavities isolated from each other on the same device.

The first circuit breaker 12-1 can also be a circuit breaker group consisting of a single or multiple circuit breakers, each circuit breaker respectively discharges liquid to the liquid outlet pipeline 5, the liquid return pipeline 8, and the exogenous replacement fluid container. The pipeline 14 and the return pipeline 15 of the exogenous replacement fluid container are linked to control;

The second circuit breaker 12-2 can also be a circuit breaker group composed of a single or multiple circuit breakers, and each circuit breaker is connected to the liquid outlet pipeline 5, the liquid return pipeline 8, and the outlet pipe of the exogenous replacement fluid container respectively. 14, exogenous replacement fluid container return line 15 for linkage control.

The exchange volume of the first liquid circulation system is 100-500ml.

The first circuit breaker 12-1 and the second circuit breaker 12-2 are provided with fault alarms.

The liquid outlet pipeline 5 or the liquid return pipeline 8 is also provided with a flow rate detection device.

There may also be more than two replacement fluid containers 7 in the first liquid circulation system.

Embodiment 3: As shown in Figures 3, 4, and 7, it is a pre-dilution filtration mode structure. When it is a filtration mode, the replacement fluid/dialysis fluid container is usually called a replacement fluid container; exogenous replacement fluid/dialysis fluid The container is usually called the exogenous replacement fluid container. The replacement fluid and the dialysate are the same liquid, and the container containing the liquid is also the same container. If the name of each component of the container involves the words "replacement" and "dialysis", different names of "replacement" and "dialysis" should be selected according to the different treatment modes.

A continuous CRRT machine capacity balance device with two circuit breakers, including a blood circulation system composed of an inlet line 1, a blood pump 2, a hollow fiber dialyzer 3, and a return line 4, and a liquid outlet line 5, a liquid pump 6. The first liquid circulation system composed of the replacement fluid container 7, the hollow fiber dialyzer 3, and the liquid return line 8;

The blood circulation system and the first liquid circulation system use a common hollow fiber dialyzer 3, and the blood in the blood circulation system and the replacement fluid in the first liquid circulation system perform solute exchange through the common hollow fiber dialyzer 3;

The hollow fiber dialyzer 3 includes a blood inlet 9-1, a blood outlet 9-2, a replacement fluid outlet 10, a replacement fluid inlet 11, and the replacement fluid outlet 10 and the replacement fluid inlet 11 are collectively referred to as the liquid port of the hollow fiber dialyzer;

After one end of the blood inlet line 1 is introduced into the blood vessel of the patient, the blood pump 2 is connected to the blood inlet 9-1 of the hollow fiber dialyzer 3 through the other end, and one end of the blood return line 4 is connected to the blood outlet of the hollow fiber dialyzer 3 9-2, the other end returns the blood to the patient;

There are two replacement fluid containers 7 in the first liquid circulation system, which are the first replacement fluid container 7-1 and the second replacement fluid container 7-2.

One end of the liquid outlet pipeline 5 is connected to the replacement fluid outlet 10 of the hollow fiber dialyzer 3, and the other end is divided into two paths after passing through the liquid pump 6, and one path is connected to the first replacement fluid container 7 after passing through the first circuit breaker 12-1. -1, the other path passes through the second circuit breaker 12-2 and then connects to the second replacement fluid container 7-2;

One end of the outlet pipeline 5 can be connected to the replacement fluid outlet 10 of the hollow fiber dialyzer 3, and can also be connected to the replacement fluid inlet 11; if one end of the outlet pipeline 5 is connected to the replacement fluid outlet of the hollow fiber dialyzer 3 10, the replacement fluid inlet 11 of the hollow fiber dialyzer 3 is sealed; if one end of the outlet line 5 is connected to the replacement fluid inlet 11 of the hollow fiber dialyzer 3, the replacement fluid outlet 10 of the hollow fiber dialyzer 3 is sealed.

One end of the liquid return line 8 is connected to the blood vessel line 1, and the other end is divided into two paths, one path passes through the first circuit breaking device 12-1 and then connects to the first replacement fluid container 7-1, and the other path passes through the second circuit breaking device 12 After -2, connect the second replacement fluid container 7-2;

It also includes the exogenous replacement fluid container 13, the exogenous replacement fluid container outlet pipeline 14, the liquid pump 6, the circuit breaker 12-1, 12-2, the replacement fluid container 7, and the return liquid of the exogenous replacement fluid container. The second liquid circulation system that pipeline 15 forms;

One end of the outlet pipeline 14 of the exogenous replacement liquid container is connected to the exogenous replacement liquid container 13, and the other end is divided into two paths after passing through the liquid pump 6, and one end is connected to the second replacement liquid after passing through the first circuit breaker 12-1. Container 7-2, the other path passes through the second circuit breaker 12-2 and then connects to the first replacement fluid container 7-1;

One end of the exogenous replacement liquid container return line 15 is connected to the exogenous replacement liquid container 13, and the other end is divided into two paths, one of which passes through the first circuit breaking device 12-1 and then connects to the second replacement liquid container 7-2. The other path passes through the second circuit breaker 12-2 and then connects to the first replacement fluid container 7-1;

The first circuit breaking device 12-1 and the second circuit breaking device 12-2 are linked control, when the first circuit breaking device 12-1 is opened, the second circuit breaking device 12-2 is automatically closed, when the first circuit breaking device 12-1 When closed, the second circuit breaker 12-2 is automatically opened.

As shown in FIG. 4 , an ultrafiltration system composed of an ultrafiltration pipeline 16 , an ultrafiltration pump 17 , and an ultrafiltration container 18 is provided at the front end of the outlet pipeline 5 .

The ultrafiltration system also includes a flow monitoring device, which is installed on the ultrafiltration pipeline 16 to monitor the flow rate and flow rate of the liquid in the ultrafiltration pipeline 16 .

The first circuit breaking device 12-1 and the second circuit breaking device 12-2 are pipeline clips.

The replacement fluid container 7 can also be two cavities isolated from each other on the same device.

The first circuit breaker 12-1 can also be a circuit breaker group consisting of a single or multiple circuit breakers, each circuit breaker respectively discharges liquid to the liquid outlet pipeline 5, the liquid return pipeline 8, and the exogenous replacement fluid container. The pipeline 14 and the return pipeline 15 of the exogenous replacement fluid container are linked to control;

The second circuit breaker 12-2 can also be a circuit breaker group composed of a single or multiple circuit breakers, and each circuit breaker is connected to the liquid outlet pipeline 5, the liquid return pipeline 8, and the outlet pipe of the exogenous replacement fluid container respectively. 14, exogenous replacement fluid container return line 15 for linkage control.

The exchange volume of the first liquid circulation system is 100-500ml.

The first circuit breaker 12-1 and the second circuit breaker 12-2 are provided with fault alarms.

The liquid outlet pipeline 5 or the liquid return pipeline 8 is also provided with a flow rate detection device.

There may also be more than two replacement fluid containers 7 in the first liquid circulation system.

Embodiment 4: As shown in Figures 5, 6, and 7, it is a dialysis mode structure. When it is a dialysis mode, the replacement fluid/dialysis fluid container is usually called a dialysate container; the exogenous replacement fluid/dialysis fluid container is usually called a dialysate container. For exogenous dialysate containers, the replacement fluid and the dialysate are the same liquid, and the container containing the liquid is also the same container. If the names of the components of the container involve the words "replacement" and "dialysis", according to the treatment Depending on the mode, choose different names for "replacement" and "dialysis".

A continuous CRRT machine capacity balance device with two circuit breakers, including a blood circulation system composed of an inlet line 1, a blood pump 2, a hollow fiber dialyzer 3, and a return line 4, and a liquid outlet line 5, a liquid pump 6. The first liquid circulation system composed of the dialysate container 7, the hollow fiber dialyzer 3, and the liquid return line 8;

The blood circulation system and the first liquid circulation system use a common hollow fiber dialyzer 3, and the blood in the blood circulation system and the dialysate in the first liquid circulation system perform solute exchange through the common hollow fiber dialyzer 3;

The hollow fiber dialyzer 3 includes a blood inlet 9-1, a blood outlet 9-2, a dialysate outlet 10, a dialysate inlet 11, and the dialysate outlet 10 and the dialysate inlet 11 are collectively referred to as the liquid port of the hollow fiber dialyzer;

After one end of the blood inlet line 1 is introduced into the blood vessel of the patient, the blood pump 2 is connected to the blood inlet 9-1 of the hollow fiber dialyzer 3 through the other end, and one end of the blood return line 4 is connected to the blood outlet of the hollow fiber dialyzer 3 9-2, the other end returns the blood to the patient;

There are two dialysate containers 7 in the first liquid circulation system, which are the first dialysate container 7-1 and the second dialysate container 7-2.

One end of the outlet pipeline 5 is connected to the dialysate outlet 10 of the hollow fiber dialyzer 3, and the other end is divided into two paths after passing through the liquid pump 6, and one end is connected to the first dialysate container 7 after passing through the first circuit breaker 12-1 -1, the other way passes through the second circuit breaker 12-2 and connects to the second dialysate container 7-2;

One end of the liquid return line 8 is connected to the dialysate inlet 11 of the hollow fiber dialyzer 3, and the other end is divided into two paths, one path passes through the first circuit breaker 12-1 and is connected to the first dialysate container 7-1, and the other end is connected to the first dialysate container 7-1. Connect the second dialysate container 7-2 after passing through the second circuit breaker 12-2;

Also includes exogenous dialysate container 13, exogenous dialysate container outlet pipeline 14, liquid pump 6, circuit breaker 12-1, 12-2, dialysate container 7, exogenous dialysate container return fluid The second liquid circulation system that pipeline 15 forms;

One end of the exogenous dialysate container outlet pipeline 14 is connected to the exogenous dialysate container 13, and the other end is divided into two paths after passing through the liquid pump 6, and one end is connected to the second dialysate after passing through the first circuit breaker 12-1. The container 7-2, the other way is connected to the first dialysate container 7-1 after passing through the second circuit breaker 12-2;

One end of the exogenous dialysate container return line 15 is connected to the exogenous dialysate container 13, and the other end is divided into two paths, one path passes through the first circuit breaker 12-1 and then connects to the second dialysate container 7-2, The other path passes through the second circuit breaker 12-2 and then connects to the first dialysate container 7-1;

The first circuit breaking device 12-1 and the second circuit breaking device 12-2 are linked control, when the first circuit breaking device 12-1 is opened, the second circuit breaking device 12-2 is automatically closed, when the first circuit breaking device 12-1 When closed, the second circuit breaker 12-2 is automatically opened.

As shown in FIG. 6 , an ultrafiltration system consisting of an ultrafiltration pipeline 16 , an ultrafiltration pump 17 , and an ultrafiltration container 18 is provided at the front end of the outlet pipeline 5 .

The ultrafiltration system also includes a flow monitoring device, which is installed on the ultrafiltration pipeline 16 to monitor the flow rate and flow rate of the liquid in the ultrafiltration pipeline 16 .

The first circuit breaking device 12-1 and the second circuit breaking device 12-2 are pipeline clips.

The dialysate container 7 can also be two cavities isolated from each other on the same device.

The first circuit breaker 12-1 can also be a circuit breaker group consisting of a single or multiple circuit breakers, and each circuit breaker discharges liquid to the liquid outlet pipeline 5, the liquid return pipeline 8, and the exogenous dialysate container respectively. The pipeline 14 and the return pipeline 15 of the exogenous dialysate container are linked to control;

The second circuit breaker 12-2 can also be a circuit breaker group composed of a single or multiple circuit breakers, and each circuit breaker is connected to the liquid outlet pipeline 5, the liquid return pipeline 8, and the fluid outlet pipe of the exogenous dialysate container respectively. 14, exogenous dialysate container return line 15 for linkage control.

The exchange volume of the first liquid circulation system is 100-500ml.

The first circuit breaker 12-1 and the second circuit breaker 12-2 are provided with fault alarms.

The liquid outlet pipeline 5 or the liquid return pipeline 8 is also provided with a flow rate detection device.

There may also be more than two dialysate containers 7 in the first liquid circulation system.

Claims (10)

1. A continuous CRRT machine capacity balance device with two circuit breakers, including a blood circulation system composed of an inlet line, a blood pump, a hollow fiber dialyzer, and a blood return line, and a liquid outlet line, a liquid pump, and a replacement fluid / The first liquid circulation system composed of dialysate container, hollow fiber dialyzer, and return line; The blood circulation system and the first liquid circulation system use a common hollow fiber dialyzer, and the blood in the blood circulation system and the replacement fluid/dialysis fluid in the first liquid circulation system perform solute exchange through the common hollow fiber dialyzer; The hollow fiber dialyzer includes a blood inlet, a blood outlet, a replacement fluid/dialysis fluid outlet, a replacement fluid/dialysis fluid inlet, a replacement fluid/dialysis fluid outlet, and a replacement fluid/dialysis fluid inlet are collectively referred to as hollow fiber dialyzer liquid ports; After one end of the blood inlet line is introduced into the blood vessel of the patient, the other end is connected to the blood inlet of the hollow fiber dialyzer through the blood pump, and one end of the blood return line is connected to the blood outlet of the hollow fiber dialyzer, and the other end returns the blood to the patient in vivo; It is characterized in that: there are two replacement fluid/dialysis fluid containers in the first liquid circulation system, which are the first replacement fluid/dialysis fluid container and the second replacement fluid/dialysis fluid container; One end of the liquid outlet pipeline is connected to the liquid port of the hollow fiber dialyzer, and the other end is divided into two paths after passing through the liquid pump, one path is connected to the first replacement fluid/dialysate container after passing through the first circuit breaker, and the other path passes through the second circuit breaker The device is connected to the second replacement fluid/dialysis fluid container; One end of the liquid return line is connected to the liquid port of the hollow fiber dialyzer or the blood inlet line, and the other end is divided into two lines, one line passes through the first circuit breaker and then connects to the first replacement fluid/dialysate container, and the other line passes through the second circuit breaker The device is connected to the second replacement fluid/dialysis fluid container; Also includes exogenous replacement fluid/dialysis fluid container, exogenous replacement fluid/dialysis fluid container outlet line, liquid pump, circuit breaker, replacement fluid/dialysis fluid container, exogenous replacement fluid/dialysis fluid container return The second liquid circulation system composed of liquid pipelines; One end of the outlet line of the exogenous replacement fluid/dialysis fluid container is connected to the exogenous replacement fluid/dialysis fluid container, and the other end is divided into two paths after passing through the liquid pump, and one end is connected to the second replacement fluid after passing through the first circuit breaker. / dialysate container, the other way is connected to the first replacement fluid/dialysate container after passing through the second circuit breaker; One end of the exogenous replacement fluid/dialysis fluid container return line is connected to the exogenous replacement fluid/dialysis fluid container, and the other end is divided into two paths, one of which passes through the first circuit breaker and then connected to the second replacement fluid/dialysis fluid container , and the other path is connected to the first replacement fluid/dialysate container after passing through the second circuit breaker; The first circuit breaking device and the second circuit breaking device are controlled in linkage, when the first circuit breaking device is opened, the second circuit breaking device is automatically closed, and when the first circuit breaking device is closed, the second circuit breaking device is automatically opened. 2. The continuous CRRT machine capacity balance device of two circuit breakers according to claim 1, characterized in that: the front end of the outlet pipeline is also provided with an ultrafiltration pipeline, an ultrafiltration pump, and an ultrafiltration container. ultrafiltration system. 3. The continuous type CRRT machine capacity balancing device of two circuit breakers according to claim 2, characterized in that: the ultrafiltration system also includes a flow monitoring device, and the flow monitoring device is installed on the ultrafiltration pipeline, for ultrafiltration The liquid flow rate and flow in the filter line are monitored. 4. The continuous CRRT machine capacity balance device with two breaking devices according to claim 1, characterized in that: the first breaking device and the second breaking device are pipeline clamps. 5. The continuous CRRT machine capacity balance device with two circuit breakers according to claim 1, characterized in that: the replacement fluid/dialysis fluid container can also be two cavities isolated from each other on the same device. 6. The continuous CRRT machine capacity balance device of two circuit breakers according to claim 1, characterized in that: the first circuit breaker can also be a circuit breaker group, and each circuit breaker is connected to the liquid outlet pipeline and the liquid return line respectively. Pipeline, exogenous replacement fluid/dialysis fluid container outlet pipeline, exogenous replacement fluid/dialysis fluid container return pipeline for linkage control; The second circuit breaking device can also be a group of circuit breaking devices, and each circuit breaking device is connected to the outlet pipeline, the liquid return pipeline, the outlet pipeline of the exogenous replacement fluid/dialysate container, and the outlet pipeline of the exogenous replacement fluid/dialysis fluid. The container return line is controlled in linkage. 7. The continuous CRRT machine capacity balance device with two circuit breakers according to claim 1, characterized in that: the exchange volume of the first liquid circulation system is 100-500ml. 8. The continuous CRRT machine capacity balancing device with two breakers according to claim 1, characterized in that: the first breaker and the second breaker are provided with fault alarms. 9. The continuous CRRT machine capacity balance device with two circuit breakers according to claim 1, characterized in that: a flow rate detection device is also provided on the liquid outlet pipeline or the liquid return pipeline. 10. The continuous CRRT machine capacity balance device with two circuit breakers according to claim 1, characterized in that: the replacement fluid/dialysis fluid container in the first liquid circulation system can also be set to more than two.