CN105288721A - Liquid band-aid and preparation technology thereof - Google Patents
Liquid band-aid and preparation technology thereof Download PDFInfo
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- CN105288721A CN105288721A CN201510669508.5A CN201510669508A CN105288721A CN 105288721 A CN105288721 A CN 105288721A CN 201510669508 A CN201510669508 A CN 201510669508A CN 105288721 A CN105288721 A CN 105288721A
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- 239000007788 liquid Substances 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- 238000003756 stirring Methods 0.000 claims abstract description 32
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 16
- 238000010438 heat treatment Methods 0.000 claims abstract description 16
- 238000002791 soaking Methods 0.000 claims abstract description 15
- 239000004902 Softening Agent Substances 0.000 claims abstract description 12
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 12
- 239000013003 healing agent Substances 0.000 claims abstract description 12
- 239000002904 solvent Substances 0.000 claims abstract description 12
- 239000000730 antalgic agent Substances 0.000 claims abstract description 11
- 230000002439 hemostatic effect Effects 0.000 claims abstract description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 30
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 26
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 18
- 239000009277 Panax notoginseng extract Substances 0.000 claims description 13
- GEYJUFBPCGDENK-UHFFFAOYSA-M sodium;3,8-dimethyl-5-propan-2-ylazulene-1-sulfonate Chemical group [Na+].CC(C)C1=CC=C(C)C2=C(S([O-])(=O)=O)C=C(C)C2=C1 GEYJUFBPCGDENK-UHFFFAOYSA-M 0.000 claims description 12
- 235000011187 glycerol Nutrition 0.000 claims description 11
- 239000002874 hemostatic agent Substances 0.000 claims description 10
- 239000005018 casein Substances 0.000 claims description 9
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 9
- 235000021240 caseins Nutrition 0.000 claims description 9
- 229920003063 hydroxymethyl cellulose Polymers 0.000 claims description 9
- 229940031574 hydroxymethyl cellulose Drugs 0.000 claims description 9
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 8
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 8
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 8
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 claims description 7
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 7
- 229920000153 Povidone-iodine Polymers 0.000 claims description 7
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 7
- 229960001621 povidone-iodine Drugs 0.000 claims description 7
- IYLLULUTZPKQBW-UHFFFAOYSA-N Acrinol Chemical compound CC(O)C(O)=O.C1=C(N)C=CC2=C(N)C3=CC(OCC)=CC=C3N=C21 IYLLULUTZPKQBW-UHFFFAOYSA-N 0.000 claims description 6
- 229960003333 chlorhexidine gluconate Drugs 0.000 claims description 6
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 claims description 6
- 229960004189 ethacridine lactate Drugs 0.000 claims description 6
- RXXROIWDLGTUIN-UHFFFAOYSA-N zinc;(4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide Chemical compound [Zn+2].C1=CC(N)=CC=C1S(=O)(=O)[N-]C1=NC=CC=N1.C1=CC(N)=CC=C1S(=O)(=O)[N-]C1=NC=CC=N1 RXXROIWDLGTUIN-UHFFFAOYSA-N 0.000 claims description 6
- 229960002152 chlorhexidine acetate Drugs 0.000 claims description 5
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 claims description 5
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 4
- 108010010803 Gelatin Proteins 0.000 claims description 4
- 229920000159 gelatin Polymers 0.000 claims description 4
- 239000008273 gelatin Substances 0.000 claims description 4
- 235000019322 gelatine Nutrition 0.000 claims description 4
- 235000011852 gelatine desserts Nutrition 0.000 claims description 4
- 239000001814 pectin Substances 0.000 claims description 4
- 229920001277 pectin Polymers 0.000 claims description 4
- 235000010987 pectin Nutrition 0.000 claims description 4
- 239000000600 sorbitol Substances 0.000 claims description 4
- 239000000230 xanthan gum Substances 0.000 claims description 4
- 229920001285 xanthan gum Polymers 0.000 claims description 4
- 235000010493 xanthan gum Nutrition 0.000 claims description 4
- 229940082509 xanthan gum Drugs 0.000 claims description 4
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 3
- 239000000853 adhesive Substances 0.000 claims 2
- 230000001070 adhesive effect Effects 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 abstract description 4
- 230000004054 inflammatory process Effects 0.000 abstract description 4
- 241000894006 Bacteria Species 0.000 abstract description 3
- 229940030225 antihemorrhagics Drugs 0.000 abstract description 3
- 230000007547 defect Effects 0.000 abstract description 2
- 230000003467 diminishing effect Effects 0.000 abstract description 2
- 230000000025 haemostatic effect Effects 0.000 abstract 2
- 230000002147 killing effect Effects 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 description 21
- 206010052428 Wound Diseases 0.000 description 20
- 239000003814 drug Substances 0.000 description 6
- 239000000843 powder Substances 0.000 description 4
- 230000000740 bleeding effect Effects 0.000 description 3
- 230000029663 wound healing Effects 0.000 description 3
- 235000003181 Panax pseudoginseng Nutrition 0.000 description 2
- 244000131316 Panax pseudoginseng Species 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 239000004745 nonwoven fabric Substances 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010048038 Wound infection Diseases 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000000922 anti-bactericidal effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
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- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to liquid band-aid and a preparation technology thereof. The liquid band-aid is prepared from the following components in percentage by weight: 5%-20% of a film-forming agent, 4%-12% of a softening agent, 0.1-8% of an antibacterial agent, 3%-10% of a haemostatic and analgetic agent, 1%-5% of a healing agent, and 53%-83% of a solvent. The preparation technology comprises the following steps: adding 5%-20% of the film-forming agent and 53-83% of the solvent into a reactor, and soaking for 1-2 h; heating to 65 DEG C to 70 DEG C so that the film-forming agent completely swells; and sequentially adding the softening agent, the antibacterial agent, the haemostatic and analgetic agent and the healing agent into the reactor under stirring, and uniformly stirring to prepare the liquid band-aid. The liquid band-aid overcomes the defects that the traditional band-aid is not attractive, and the wound can not move freely. The liquid band-aid has the characteristics of being rapid in hemostatic effect, strong in inflammation diminishing and bacteria killing properties, and low in cost, and the wound part can move freely.
Description
Technical Field
The invention relates to a band-aid. In particular to a liquid woundplast which can be conveniently smeared on a wound and can quickly isolate the wound from the outside to diminish inflammation and sterilize and a preparation process thereof.
Background
In daily life, people often leave wounds due to careless injuries to the body. If not treated in a timely manner, such wounds are often infected, with more serious consequences, especially in the summer, and are prone to inflammation.
For such wounds, a band-aid is usually applied to the small wound surface to achieve the purpose of diminishing inflammation and sterilizing. The common band-aid in the market is stuck on a small wound surface, wherein one band-aid is medical adhesive tape and non-woven fabric, and the other band-aid is PU film and non-woven fabric. The band-aid with the structure mode is attached to the wound surface, so that the free movement of the wound part is influenced, and the appearance is also influenced.
Disclosure of Invention
The invention aims to solve the technical problem of providing a liquid band-aid which does not affect the appearance and has free movement of a wound and a preparation process thereof.
The technical scheme adopted by the invention is as follows: a liquid band-aid comprises the following components in percentage by weight: 5 to 20 percent of film forming agent, 4 to 12 percent of softening agent, 0.1 to 8 percent of antibacterial agent, 3 to 10 percent of hemostatic and analgesic agent, 1 to 5 percent of healing agent and 53 to 83 percent of solvent.
The film forming agent is one of casein, polyvinyl alcohol, hydroxymethyl cellulose, polyvinylpyrrolidone, pectin, gelatin and xanthan gum.
The softening agent is one of glycerin, propylene glycol and sorbitol.
The antibacterial agent is one of povidone iodine, chlorhexidine acetate, chlorhexidine gluconate, and ethacridine lactate.
The hemostatic and analgesic agent is Panax notoginseng extract.
The healing agent is sodium azulene sulfonate or sulfadiazine zinc.
The solvent is 35-45% ethanol water solution.
A preparation process of a liquid band-aid comprises the following steps:
1) adding 5-20% of film forming agent and 53-83% of solvent into a reactor, and soaking for 1-2 hours;
2) heating to 65-70 ℃ to fully swell the film-forming agent;
3) adding softening agent, antibacterial agent, hemostatic and analgesic agent and healing agent under stirring, and stirring.
According to the liquid band-aid and the preparation process thereof, the film-forming agent, the softening agent and the solvent can be prepared into liquid convenient to apply, so that a wound is quickly isolated from the outside, and the normal movement of an applied part is not influenced; the antibacterial agent can prevent wound infection; hemostatic agents prevent continued bleeding from the wound; the healing agent can promote wound healing. Therefore, the invention solves the defects of influence on the appearance and the loose movement of the wound of the traditional wound plaster. The invention has the characteristics of quick hemostasis effect, strong anti-inflammatory and bactericidal capacity, free movement of wound parts and low cost.
Detailed Description
The liquid band-aid and the preparation process thereof according to the present invention will be described in detail with reference to the following examples.
The invention relates to a liquid band-aid, which comprises the following components in percentage by weight: 5 to 20 percent of film forming agent, 4 to 12 percent of softening agent, 0.1 to 8 percent of antibacterial agent, 3 to 10 percent of hemostatic and analgesic agent, 1 to 5 percent of healing agent and 53 to 83 percent of solvent. Wherein,
the film forming agent is one of casein, polyvinyl alcohol, hydroxymethyl cellulose, polyvinylpyrrolidone, pectin, gelatin and xanthan gum;
the softening agent is one of glycerin, propylene glycol and sorbitol;
the antibacterial agent is one of povidone iodine, chlorhexidine acetate, chlorhexidine gluconate and ethacridine lactate;
the hemostatic and analgesic agent is Panax notoginseng extract;
the healing agent is sodium azulene sulfonate or sulfadiazine zinc;
the solvent is 35-45% ethanol water solution.
The invention relates to a preparation process of a liquid band-aid, which comprises the following steps:
1) adding 5-20% of film forming agent and 53-83% of solvent into a reactor, and soaking for 1-2 hours;
2) heating to 65-70 deg.c to swell the filming agent;
3) adding softening agent, antibacterial agent, hemostatic and analgesic agent and healing agent under stirring, and stirring.
Specific examples are given below:
example 1: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 5g of casein and 83g of 35% ethanol into a reactor, and soaking for 1 hour;
2) heating to 65-70 deg.c to swell casein fully;
3) and (3) sequentially adding 7.5g of glycerol, 0.5g of povidone iodine powder, 3g of panax notoginseng extract and 1g of sodium azulene sulfonate under stirring, and uniformly stirring to obtain the traditional Chinese medicine.
Example 2: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 15g of polyvinyl alcohol and 66.5g of 40% ethanol into a reactor, and soaking for 1.5 hours;
2) heating to 65-70 deg.c to swell polyvinyl alcohol fully;
3) and sequentially adding 6g of glycerol, 2.5g of povidone iodine powder, 5g of panax notoginseng extract and 5g of sodium azulene sulfonate under stirring, and uniformly stirring to obtain the traditional Chinese medicine.
Example 3: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 20g of hydroxymethyl cellulose and 53g of 45% ethanol into a reactor, and soaking for 2 hours;
2) heating to 65-70 deg.c to swell hydroxymethyl cellulose fully;
3) and sequentially adding 12g of propylene glycol, 5g of povidone iodine powder, 7g of panax notoginseng extract and 3g of sodium azulene sulfonate under stirring, and uniformly stirring.
Example 4: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 6g of polyvinylpyrrolidone and 69g of 45% ethanol into a reactor, and soaking for 2 hours;
2) heating to 65-70 deg.c to swell polyvinyl pyrrolidone fully;
3) and sequentially adding 10g of glycerol, 2g of ethacridine lactate, 10g of panax notoginseng extract and 3g of sodium azulene sulfonate under stirring, and uniformly stirring.
Example 5: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 6g of casein and 80.5g of 35% ethanol into a reactor, and soaking for 1.5 hours;
2) heating to 65-70 deg.c to swell casein fully;
3) and (3) adding 7g of glycerol, 0.5g of chlorhexidine acetate, 4g of panax notoginseng extract and 2g of sodium azulene sulfonate in sequence under stirring, and uniformly stirring to obtain the traditional Chinese medicine.
Example 6: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 12g of polyvinyl alcohol and 63g of 40% ethanol into a reactor, and soaking for 1 hour;
2) heating to 65-70 deg.c to swell polyvinyl alcohol fully;
3) and sequentially adding 12g of glycerol, 3g of chlorhexidine gluconate, 5g of panax notoginseng extract and 5g of sodium azulene sulfonate under stirring, and uniformly stirring to obtain the traditional Chinese medicine.
Example 7: taking 100g as an example for preparation, the following components are taken by weight:
1) 6g of hydroxymethyl cellulose and 70g of 45% ethanol are added into a reactor and soaked for 1.5 hours;
2) heating to 65-70 deg.c to swell hydroxymethyl cellulose fully;
3) and sequentially adding 10g of propylene glycol, 5g of ethacridine lactate, 7g of panax notoginseng extract and 2g of sodium azulene sulfonate under stirring, and uniformly stirring.
Example 8: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 5g of pectin and 71g of 45% ethanol into a reactor, and soaking for 2 hours;
2) heating to 65-70 deg.c to swell polyvinyl pyrrolidone fully;
3) and sequentially adding 7g of glycerol, 8g of chlorhexidine gluconate, 6g of panax notoginseng extract and 3g of sodium azulene sulfonate while stirring, and uniformly stirring to obtain the traditional Chinese medicine.
Example 9: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 9g of xanthan gum and 65g of 40% ethanol into a reactor, and soaking for 1 hour;
2) heating to 65-70 deg.c to swell hydroxymethyl cellulose;
3) adding 11g of glycerol, 5g of ethacridine lactate, 7g of pseudo-ginseng extract and 3g of sulfadiazine zinc in sequence under stirring, and stirring uniformly to obtain the compound.
Example 10: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 6g of polyvinylpyrrolidone and 73g of 45% ethanol into a reactor, and soaking for 1 hour;
2) heating to 65-70 deg.c to swell polyvinyl pyrrolidone fully;
3) and adding 7g of propylene glycol, 4g of povidone iodine powder, 5g of pseudo-ginseng extract and 5g of sulfadiazine zinc in sequence under stirring, and uniformly stirring to obtain the composition.
Example 11: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 6g of casein and 78.9g of 35% ethanol into a reactor, and soaking for 1.5 hours;
2) heating to 65-70 deg.c to swell casein fully;
3) adding 7g of glycerol, 0.1g of chlorhexidine acetate, 4g of panax notoginseng extract and 4g of sulfadiazine zinc in sequence under stirring, and stirring uniformly to obtain the oral liquid.
Example 12: taking 100g as an example for preparation, the following components are taken by weight:
1) adding 15g of gelatin and 71g of 35% ethanol into a reactor, and soaking for 1.5 hours;
2) heating to 65-70 deg.c to swell hydroxymethyl cellulose fully;
3) and sequentially adding 4g of sorbitol, 2.5g of chlorhexidine gluconate, 4g of panax notoginseng extract and 3.5g of sodium azulene sulfonate while stirring, and uniformly stirring to obtain the traditional Chinese medicine.
The invention has been described in detail with reference to the specific embodiments and the specific features of the liquid band-aid, but it is not limited thereto, and it is intended that the invention shall be construed as including all such modifications and alterations insofar as they come within the spirit and scope of the invention as defined by the appended claims.
In the 12 examples, 30 parts of samples are prepared according to the formula in each example, 360 parts of samples are prepared, volunteers willing to try are searched, and when accidental skin scratches occur, the product is applied to the wound, so that the wound is prevented from being infected by bacteria, bleeding is stopped, pain is relieved, and wound healing is promoted. The trial result shows that the 12 products of the embodiment can quickly isolate the wound from the outside, prevent bacterial infection, relieve pain and heal quickly, and have no wound and mouthfeel dyed during trial, and the significant efficiency is 100%. Therefore, the product of the patent has the effects of preventing the wound from being infected by bacteria, stopping bleeding and relieving pain and promoting wound healing, and is worthy of popularization.
Claims (8)
1. The liquid band-aid is characterized by comprising the following components in percentage by weight: 5 to 20 percent of film forming agent, 4 to 12 percent of softening agent, 0.1 to 8 percent of antibacterial agent, 3 to 10 percent of hemostatic and analgesic agent, 1 to 5 percent of healing agent and 53 to 83 percent of solvent.
2. The liquid band-aid according to claim 1, wherein the film-forming agent is one of casein, polyvinyl alcohol, hydroxymethyl cellulose, polyvinyl pyrrolidone, pectin, gelatin and xanthan gum.
3. The liquid band-aid according to claim 1, wherein the softening agent is one of glycerin, propylene glycol and sorbitol.
4. The liquid band-aid according to claim 1, wherein the antibacterial agent is one of povidone iodine, chlorhexidine acetate, chlorhexidine gluconate, ethacridine lactate.
5. The liquid adhesive bandage of claim 1, wherein the hemostatic and analgesic agent is Panax notoginseng extract.
6. The liquid adhesive bandage of claim 1 wherein the healing agent is sodium azulene sulfonate or zinc sulfadiazine.
7. The liquid band-aid according to claim 1, characterized in that said solvent is 35% -45% ethanol aqueous solution.
8. The preparation process of the liquid band-aid of claim 1, which is characterized by comprising the following steps:
1) adding 5-20% of film forming agent and 53-83% of solvent into a reactor, and soaking for 1-2 hours;
2) heating to 65-70 ℃ to fully swell the film-forming agent;
3) adding softening agent, antibacterial agent, hemostatic and analgesic agent and healing agent under stirring, and stirring.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510669508.5A CN105288721B (en) | 2015-10-16 | 2015-10-16 | A kind of liquid adhesive bandage and its preparation process |
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| CN201510669508.5A CN105288721B (en) | 2015-10-16 | 2015-10-16 | A kind of liquid adhesive bandage and its preparation process |
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| CN105288721A true CN105288721A (en) | 2016-02-03 |
| CN105288721B CN105288721B (en) | 2018-08-28 |
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| CN105816547A (en) * | 2016-03-30 | 2016-08-03 | 吴美燕 | Method for preparing band-aid unguent |
| CN105999393A (en) * | 2016-07-15 | 2016-10-12 | 蓝佳堂生物医药（福建）有限公司 | Liquid band-aid and preparation method thereof |
| CN106075560A (en) * | 2016-07-26 | 2016-11-09 | 上海第二工业大学 | A kind of preparation method of polymeric liquid adhesive bandage |
| CN106540316A (en) * | 2016-12-08 | 2017-03-29 | 苏州艾博迈尔新材料有限公司 | A kind of antibacterial liquid medical dressing and preparation method thereof |
| CN106727446A (en) * | 2016-12-26 | 2017-05-31 | 广州立白企业集团有限公司 | Film-forming composition, diaphragm and application |
| CN106924803A (en) * | 2017-05-05 | 2017-07-07 | 江南大学 | A kind of high-performance medical use liquid adhesive bandage and preparation method thereof |
| CN107308144A (en) * | 2017-06-29 | 2017-11-03 | 杨阳 | A kind of liquid preparation and its preparation method and application |
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| CN110201218A (en) * | 2018-12-23 | 2019-09-06 | 山东泰开制药有限公司 | Liquid adhesive bandage and preparation method thereof |
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| CN113425503A (en) * | 2021-06-24 | 2021-09-24 | 上海海洋大学 | Compound anti-inflammatory composition band-aid and preparation method thereof |
| WO2022234889A1 (en) * | 2021-05-03 | 2022-11-10 | 수바이오 주식회사 | Adhesive transparent multifunctional wound covering material and method for manufacturing same |
| CN118649284A (en) * | 2024-07-01 | 2024-09-17 | 天津大学 | A liquid dressing containing mesenchymal stem cell exosomes and its preparation method and application |
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| CN105999393A (en) * | 2016-07-15 | 2016-10-12 | 蓝佳堂生物医药（福建）有限公司 | Liquid band-aid and preparation method thereof |
| CN106075560A (en) * | 2016-07-26 | 2016-11-09 | 上海第二工业大学 | A kind of preparation method of polymeric liquid adhesive bandage |
| CN106540316A (en) * | 2016-12-08 | 2017-03-29 | 苏州艾博迈尔新材料有限公司 | A kind of antibacterial liquid medical dressing and preparation method thereof |
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| CN108904530A (en) * | 2018-08-03 | 2018-11-30 | 安徽省银锂子生物科技发展有限公司 | A kind of bactericidal nano-silver hemostatic composition |
| CN109464696A (en) * | 2018-12-05 | 2019-03-15 | 福建易元生物医药有限公司 | A kind of atomizing liquid adhesive bandage |
| CN110201218A (en) * | 2018-12-23 | 2019-09-06 | 山东泰开制药有限公司 | Liquid adhesive bandage and preparation method thereof |
| CN109731132A (en) * | 2019-01-30 | 2019-05-10 | 中国人民解放军西部战区总医院 | The liquid bandage of alleviation arthralgia containing Ginger P.E |
| CN109731132B (en) * | 2019-01-30 | 2021-05-11 | 中国人民解放军西部战区总医院 | Liquid bandage containing rhizoma Zingiberis recens extract for relieving arthralgia |
| CN111184906A (en) * | 2020-02-19 | 2020-05-22 | 江南大学 | A kind of liquid dressing based on PVA and preparation method thereof |
| CN111184906B (en) * | 2020-02-19 | 2020-12-29 | 江南大学 | A kind of liquid dressing based on PVA and preparation method thereof |
| CN112245652A (en) * | 2020-10-16 | 2021-01-22 | 合肥贝壳派创新科技有限公司 | Bacteriostatic liquid band-aid capable of quickly forming film and preparation method thereof |
| WO2022234889A1 (en) * | 2021-05-03 | 2022-11-10 | 수바이오 주식회사 | Adhesive transparent multifunctional wound covering material and method for manufacturing same |
| CN113425503A (en) * | 2021-06-24 | 2021-09-24 | 上海海洋大学 | Compound anti-inflammatory composition band-aid and preparation method thereof |
| CN118649284A (en) * | 2024-07-01 | 2024-09-17 | 天津大学 | A liquid dressing containing mesenchymal stem cell exosomes and its preparation method and application |
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Effective date of registration: 20160222 Address after: 300308, B205, building 8, airport business park, 80 Ring Road North, Tianjin Airport Economic Zone Applicant after: Tianjin top pharmaceutical technology Co., Ltd. Address before: 300380 Tianjin city Xiqing District Zhangjiawo Industrial Zone Fengze Road No. 6 Applicant before: Tianjin Jing Shuo Science and Trade Co., Ltd. |
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Address after: 300308, B205, building 8, airport business park, 80 Ring Road North, Tianjin Airport Economic Zone Applicant after: Tianjin top pharmaceutical Limited by Share Ltd Address before: 300308, B205, building 8, airport business park, 80 Ring Road North, Tianjin Airport Economic Zone Applicant before: Tianjin top pharmaceutical technology Co., Ltd. |
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Denomination of invention: A liquid band aid and its preparation technology Effective date of registration: 20210318 Granted publication date: 20180828 Pledgee: Business Department of Bank of Tianjin Co.,Ltd. Pledgor: Tianjin top pharmaceutical Limited by Share Ltd. Registration number: Y2021120000008 |