CN104012770A - Selenium-containing multi-vitamin preparation capable of accelerating antibiotic metabolism of live pigs and preparing method of selenium-containing multi-vitamin preparation - Google Patents
Selenium-containing multi-vitamin preparation capable of accelerating antibiotic metabolism of live pigs and preparing method of selenium-containing multi-vitamin preparation Download PDFInfo
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Abstract
The invention discloses a selenium-containing multi-vitamin traditional Chinese medicine preparation and applications thereof, belonging to the technical field of preparation and application of feed additives. The invention particularly relates to the field of preparation and application of a traditional Chinese medicine preparation for live pig feeding. The selenium-containing multi-vitamin traditional Chinese medicine preparation is characterized by comprising selenium, vitamin E, vitamin C, vitamin D, tuckahoe and houttuynia cordata, and is used as a nutritious additive for live pig feeding. The selenium-containing multi-vitamin traditional Chinese medicine preparation is safe and effective. With the preparation, the antibiotic metabolism in live pig bodies can be accelerated, and the time of antibiotics staying in live pig bodies is shortened. Besides, the preparation has nerve calming and growth promoting effects on the live pigs, thereby reducing feeding cost and increasing feeding benefit.
Description
Technical field:
The invention belongs to preparation and the application of Chinese medicine preparation, relate in particular to a kind of preparation and application of feed addictive of feeding live pig.
Technical background:
Along with the improvement day by day of people's living standard, food-safety problem has become the focus of global concern.What people pursued now is not only to feed oneself, and meets human body and allays one's hunger, but eat the nutrition food of health again.The food of edible antibiotic residue can cause the growth inhibition of beneficial bacterium in human body intestinal canal, makes pathogenic bacteria, candida albicans breeding, causes human body to produce drug resistance to antibiotic.Therefore, antibiotic etc residue problem is one of problem of paying close attention to most of consumers in general and entire society in the food including pork in recent years.
In pig-breeding process, the control of common disease all be unable to do without antibiotic.Along with a large amount of extensive uses of antibiotic, not only cause the drug resistance of live pig, also cause containing in pork the residue of high concentration.And antibiotic residue cannot be removed by methods such as cleaning, immersion, heating in pork, therefore, antibiotic residue has a strong impact on meat quality, causes huge economic loss to pig-breeding industry.
Shorten common antibiotics residence time in pork body by certain nutrient feed additive of feeding and be not only the science difficult problem of pendulum in face of ours, and have important application value, but have no the research report of this respect.
Summary of the invention:
Goal of the invention: the invention provides a kind of preparation method and application thereof containing selenium multidimensional Chinese medicine preparation, can shorten the residence time of antibiotic in live pig body.
Technical scheme:
A kind of containing selenium multidimensional Chinese medicine preparation, it is characterized by: formed by selenium, vitamin E, Cobastab, vitamin C, Poria cocos and cordate houttuynia; Meter by weight, selenium 0.02-0.04 part, vitamin E2-3 part, vitamin B1-3 part, vitamin C 1-3 part, Poria cocos 5-7 part, cordate houttuynia 3-5 part.
Described selenium is potassium selenite.
Described a kind of preparation method containing selenium multidimensional Chinese medicine preparation, is characterized in that realizing as follows, and meter by weight, by potassium selenite 0.02-0.04 part, vitamin E2-3 part, vitamin B1-3 part, vitamin C 1-3 part, Poria cocos 5-7 part, cordate houttuynia 3-5 part is mixed, and pulverizing makes.
Inventive principle:
" containing selenium multidimensional Chinese medicine preparation " the contained inorganic chelated microelement group taking selenium element as main component, vitamin E B under the Chinese medicine acting in conjunction of C family and Poria cocos and cordate houttuynia, significantly improve live pig body cell, the particularly activity of liver and kidney cells, non-oxidizability, improve the metabolic function to taking in antibiotic, harmful element etc. in body, shorten its residence time in live pig body, reduce production costs, increase culture benefit.Concerning consumer, can eliminate Pork Security hidden danger, improve meat quality, for consumers in general's food security and health contribute.
Inventor's process long term test discovery inorganic selenium in a large number use can cause toxic reaction, therefore the consumption of selenium must strictly limit, the present invention adopts fixed proportion selenium, and it can realize the object of the invention, but higher than causing toxicity after its ratio.Lower than this ratio DeGrain.
Beneficial effect:
1, the present invention's safety, effective.Can accelerate the metabolism of antibiotic in live pig body, shorten its residence time in live pig body; Meanwhile, live pig is had calm the nerves, growth promoting function, evidence, in identical feeding time, pork rate of body weight gain improve about 2-3%.Reduce aquaculture cost, increase culture benefit.
Detailed description of the invention
Embodiment 1
Described a kind of preparation method containing selenium multidimensional Chinese medicine preparation, is characterized in that realizing as follows, meter by weight, and by 0.02 part of potassium selenite, vitamin E2 part, vitamin B1 part, 1 part of vitamin C, 5 parts, Poria cocos, 3 parts of mixing of cordate houttuynia, pulverizing makes.
Embodiment 2
Described a kind of preparation method containing selenium multidimensional Chinese medicine preparation, is characterized in that realizing as follows, meter by weight, and by 0.04 part of potassium selenite, 3 parts of vitamin Es, vitamin B3 part, 3 parts of vitamin Cs, 7 parts, Poria cocos, 5 parts of mixing of cordate houttuynia, pulverizing makes.
Embodiment 3
Described a kind of preparation method containing selenium multidimensional Chinese medicine preparation, is characterized in that realizing as follows, meter by weight, and by 0.03 part of potassium selenite, vitamin E2 .5 part, vitamin B2 part, Catergen part, 6 parts, Poria cocos, 4 parts of mixing of cordate houttuynia, pulverizing makes.
Embodiment 4
1, grouping and administration
Commodity select body weight to reach the good individuality of health, body condition of 60kg, raise separately, by the close principle random packet of body weight.Test provides with pig and daily ration effluent south agriculture-countryside-farmer group; Preparation is provided by research and development centre of Jiangsu Haobo Agricultural Technology Development Co., Ltd..
10 every group of market pigs, be divided into 3 test group, 1 control group, totally 6 groups of Poria cocos group and cordate houttuynia groups, 3 test group 20g/ daily ration/skies that feeding contains embodiment 1-3 respectively, Poria cocos group feeding Poria cocos 20g/ daily ration/sky, cordate houttuynia group feeding cordate houttuynia 20g/ daily ration/sky, 2 control groups only have daily ration; Raise after 7-10 days, give respectively antibiotic sulphadiazine intramuscular injection in 1-2mg/kg/ days.Test group and control group successive administration sulphadiazine 5 days before blood sampling, simulation treatment cycle.
Note: 20g/ daily ration/sky, refer to 20g preparation is mixed with daily ration after every day feeding.
Table 1 market pig experimental design
| Group | Interpolation level | Commodity pig's head number |
| Test group 1 | Basal diet+embodiment 1+ sulphadiazine | 10 |
| Test group 2 | Basal diet+embodiment 2+ sulphadiazine | 10 |
| Test group 3 | Basal diet+embodiment 3+ sulphadiazine | 10 |
| Control group | Basal diet+sulphadiazine | 10 |
| Poria cocos group | Basal diet+Poria cocos+sulphadiazine | 10 |
| Cordate houttuynia group | Basal diet+cordate houttuynia+sulphadiazine | 10 |
The collection of 2.3 samples and preparation
Sampling for the first time: (antibiotic sulphadiazine successive administration after 5 days, stop using 2 hours blood-sample withdrawals)
Sampling for the second time: (taking a blood sample for the first time after 24 hours)
Sampling for the third time: (taking a blood sample for the first time after 48 hours)
The 4th sampling: (taking a blood sample for the first time after 96 hours)
The 5th sampling: (taking a blood sample for the first time after 192 hours)
The 6th sampling: (take a blood sample for the first time after 288 hours
2.4 sample antibiotic contents detect
Blood sample transfers to Henan to import and export the detection of laboratory of inspection and quarantine bureau, and provides authoritative examining report.
3 data statistical approach
Data processing and statistical analysis adopt Excel software and SPSS system program, and significant difference person adopts LSD method to carry out multiple ratio.
4 result of the tests
Table 2 assay
Take containing after selenium multidimensional Chinese medicine preparation, after live pig simulation antibiotic therapy, within 12 days, can all eliminate residual.And live pig is in the situation that normally taking antibiotic therapy, residual life, reaches more than 20 days.In addition individually dosed Poria cocos or cordate houttuynia do not accelerate metabolism effect, illustrate that the present invention is that collaborative realization of overall compound accelerated metabolism.
Claims (3)
1. containing a selenium multidimensional Chinese medicine preparation, it is characterized by: formed by selenium, vitamin E, Cobastab, vitamin C, Poria cocos and cordate houttuynia; Meter by weight, selenium 0.02-0.04 part, vitamin E 2-3 part, Cobastab 1-3 part, vitamin C 1-3 part, Poria cocos 5-7 part, cordate houttuynia 3-5 part.
2. one according to claim 1, containing selenium multidimensional Chinese medicine preparation, is characterized in that described selenium is potassium selenite.
3. an a kind of preparation method containing selenium multidimensional Chinese medicine preparation as claimed in claim 1, it is characterized in that realizing as follows, meter by weight, by potassium selenite 0.02-0.04, vitamin E 2-3 part, Cobastab 1-3 part, vitamin C 1-3 part, Poria cocos 5-7 part, cordate houttuynia 3-5 part is mixed, and pulverizing makes.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410266117.4A CN104012770B (en) | 2014-06-16 | 2014-06-16 | A kind of can improve live pig antibiotic accretion rate containing selenium multidimensional preparation and preparation method thereof |
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| CN201410266117.4A CN104012770B (en) | 2014-06-16 | 2014-06-16 | A kind of can improve live pig antibiotic accretion rate containing selenium multidimensional preparation and preparation method thereof |
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| CN104012770A true CN104012770A (en) | 2014-09-03 |
| CN104012770B CN104012770B (en) | 2016-03-16 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105146206A (en) * | 2015-09-30 | 2015-12-16 | 江苏浩波农业科技开发有限公司 | Traditional Chinese medicine composition and application thereof |
| CN106107029A (en) * | 2016-06-21 | 2016-11-16 | 宁波东瑭生物科技有限公司 | A kind of biological Chinese medicine compound preparation with degraded antibiotics of animal residual and preparation method thereof |
| CN111264694A (en) * | 2018-12-05 | 2020-06-12 | 北京康为天生物科技有限公司 | Antibiotic eliminating agent and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1537447A (en) * | 2003-04-16 | 2004-10-20 | 四川省川大三康生物工程股份有限公司 | Composite feed additive without antibiotic |
| CN1561759A (en) * | 2004-04-06 | 2005-01-12 | 李滋星 | Selenium enrivhed multiple vitamin plant powder |
| CN1957741A (en) * | 2005-11-02 | 2007-05-09 | 吴建敏 | Nuisance free premixing feedstuff for milch cow |
| CN102187956A (en) * | 2011-06-22 | 2011-09-21 | 毕景阳 | Non-antibiotic biological compound premix |
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2014
- 2014-06-16 CN CN201410266117.4A patent/CN104012770B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1537447A (en) * | 2003-04-16 | 2004-10-20 | 四川省川大三康生物工程股份有限公司 | Composite feed additive without antibiotic |
| CN1561759A (en) * | 2004-04-06 | 2005-01-12 | 李滋星 | Selenium enrivhed multiple vitamin plant powder |
| CN1957741A (en) * | 2005-11-02 | 2007-05-09 | 吴建敏 | Nuisance free premixing feedstuff for milch cow |
| CN102187956A (en) * | 2011-06-22 | 2011-09-21 | 毕景阳 | Non-antibiotic biological compound premix |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105146206A (en) * | 2015-09-30 | 2015-12-16 | 江苏浩波农业科技开发有限公司 | Traditional Chinese medicine composition and application thereof |
| CN105146206B (en) * | 2015-09-30 | 2018-08-03 | 江苏浩波农业科技开发有限公司 | A kind of Chinese medicine composition and its application |
| CN106107029A (en) * | 2016-06-21 | 2016-11-16 | 宁波东瑭生物科技有限公司 | A kind of biological Chinese medicine compound preparation with degraded antibiotics of animal residual and preparation method thereof |
| CN111264694A (en) * | 2018-12-05 | 2020-06-12 | 北京康为天生物科技有限公司 | Antibiotic eliminating agent and preparation method and application thereof |
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| CN104012770B (en) | 2016-03-16 |
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