CN103751330B - Cataplasm of tcm for the treatment of chloasma and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of cataplasm of tcm for the treatment of chloasma, medicament selection Flos Chrysanthemi of the present invention, Folium Hibisci Mutabilis, Semen phaseoli radiati, red hawthorn, Semen Persicae, Semen Ginkgo, Flos Mume, Flos Rosae Chinensis, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) combine, made by these drug regimens each efficacy of drugs produce synergism, thus effectively play the effect of Qinghuo Jiedu, blood circulation promoting and blood stasis dispelling, dissipating rashes whitening altogether.Cataplasm of tcm prescription drug of the present invention, gathers and buys and be all easier to, and drug price is also cheap, and compound method is easy, safety easy to use.Clinical observation, after using pharmaceutical formulation of the present invention to treat 2 courses for the treatment of, its total effective rate is 97.22%.

Description

Traditional Chinese medicine paste for treating pruriens and preparation method thereof

technical field

The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine paste for treating pruriens and a preparation method thereof.

Background technique

Melasma is a kind of hyperpigmentation spot, commonly known as chloasma in Western medicine. The disease is a skin disease more common in young and middle-aged women, especially pregnant women, and is prone to occur on the forehead and face. Traditional Chinese medicine believes that the occurrence of the disease is related to the dysfunction of the liver, kidney, and spleen, among which the liver is most closely related. Emotional disorders are the main cause of pruriens. Ye Tianshi said that "women take the liver as their innate nature", "Puji Fang" said that "the face is decolorized, and it is the main liver", "Surgical Heart Method" said "mostly due to depression, depression, weak blood, fire dryness and stagnation. Born on the face, women often have it." If liver qi stagnates, stagnation turns into fire for a long time, or violent anger hurts the liver, and the liver fire is strong, then the fire burns the head and face, blood stagnates, and black spots appear on the face; or worry hurts the spleen, and the spleen is unhealthy Luck, steaming on damp fire, qi and blood are not transported, and black spots appear on the face; or panic damages the kidneys, the qi mechanism is reversed, the kidney color is exposed, and dark spots appear on the face. In recent years, studies have found that poor-quality cosmetics and excessive sun exposure can cause evil toxins to invade outside, accumulate toxins on the skin, lose harmony in Qi and blood, and cause dark spots on the face. Therefore, "fire, poison, and stasis" are the main pathogenesis of dark spots, "no spots without stasis", and blood stasis is its root. Treatment should be based on clearing fire and detoxification, promoting blood circulation to remove blood stasis, and whitening spots.

At present, Western medicine does not have a unified understanding of the pathogenesis of chloasma. Previous studies have believed that endocrine disorders, ultraviolet radiation, and heredity are the main factors for the onset of chloasma. The latest research shows that the combination of various factors such as the imbalance of oxidation and anti-oxidation in the body, the change of blood rheology, the imbalance of microecology in the local skin lesion area, and the abnormal content of trace elements lead to the increase of melanin synthesis in local skin melanocytes. It is the pathogenesis of pruriens, but there is still no ideal method for the treatment of the disease.

Contents of the invention

After literature search, no traditional Chinese medicine paste for the public treatment of prurigo is found. For this reason, the present inventor has invented a kind of paste that effectively treats prurigo by local external application of Chinese medicine, therefore, the purpose of this invention is to provide a kind of Chinese medicine paste for the treatment of prurigo and preparation method thereof.

In order to achieve the above-mentioned purpose, the technical solution adopted by the present invention is that the traditional Chinese medicine paste for the treatment of prurigo is made of the following original medicines in parts by weight: 10-20 parts of white chrysanthemum, 10-20 parts of hibiscus leaf, 10-20 parts of mung bean 20 parts, 2-6 parts of red hawthorn, 2-6 parts of peach kernel, 2-6 parts of ginkgo kernel, 2-6 parts of wintersweet flower, 2-6 parts of rose flower, and 2-6 parts of fragrant angelica.

The medicine of the present invention is combined with white chrysanthemum, hibiscus leaf, mung bean, red hawthorn, peach kernel, ginkgo kernel, wintersweet flower, rose flower, and Angelica dahurica, and the combination of these medicines makes the effects of each medicine produce a synergistic effect, thereby effectively clearing the fire together Detoxification, promoting blood circulation and removing blood stasis, removing freckles and whitening.

In the formula of the present invention, white chrysanthemum is king, and its nature is pungent, sweet, bitter, slightly cold. In spring, it can dehumidify, in summer, it can quench thirst, in autumn, it can relieve dryness, and in winter, it can clear fire. "Shen Nong's Materia Medica" records that "mainly control all dizziness, swelling and pain, loss of eyesight, dead skin muscles, aversion to rheumatism, long-term use of Qi, light body and endurance." Hibiscus leaves are flat and pungent in nature. Detoxification, detumescence, and detoxification; mung beans are known as "the best food in the world, and the long grain for the world", and their medicinal value is also extremely high. "Compendium of Materia Medica" says: "Mung bean has the same effect on reducing swelling and treating acne as red bean, but the power of pressing heat and detoxifying is superior to it." It can also "relieve all poisons of gold, stone, arsenic, and vegetation"; the combination of the two medicines is a minister , to assist the power of monarch medicine to clear away heat, detoxify, and beautify the skin. Red hawthorn is sour, sweet and slightly warm, and is a good medicine for promoting blood circulation and dispelling blood stasis; peach kernels are bitter and sweet in taste, and have a wide range of effects in promoting blood circulation and removing blood stasis, and can be used to treat various diseases caused by blood stasis; ginkgo kernels are flat in nature, sweet and bitter in taste. "Fengyuan" records that it has the functions of lowering phlegm, detoxifying, and killing insects; wintersweet flower, slightly sweet, pungent, cool in nature, can clear away heat and detoxify, regulate qi and activate blood stasis, and ward off dirty fragrance; rose flower is sweet, warm in nature, and can Promote blood circulation, regulate menstruation, detoxify and reduce swelling; various medicines are used to enhance the effect of promoting blood circulation, removing blood stasis, and beautifying spots for monarchs and ministers; Fragrant Angelica dahurica is warm in nature and pungent in taste. Olive oil is the most ideal food oil, known by Westerners as "liquid gold", "vegetable oil queen", "Mediterranean nectar"; Sophora japonica honey has the functions of clearing away heat, detoxification and cooling blood of Sophora japonica, and has The effect of detoxification and moistening dryness of honey is the first-class product in honey. The three are used together to open the skin, moisten the skin, and lead the medicine directly to the sick place.

Modern pharmacological studies have shown that: chrysanthemum is rich in essential oils and chrysanthemum pigments, which can effectively inhibit the production of skin melanin, soften epidermal cells, remove skin wrinkles, and make skin white and tender; Alkali has excellent cleansing and moisturizing effects, and has a remarkable function of removing sebum. It can effectively remove impurities in the skin, thoroughly remove waste in the deep layer of the skin, and make the skin healthy, full of vitality, and rejuvenate; hibiscus leaves have anti-inflammatory and antibacterial properties. It can improve the antioxidant capacity of liver cells; the fatty oil in peach kernels can soften the cuticle of the skin, moisturize the skin, and inhibit bacteria. Hydrocyanic acid in peach kernels can eliminate pigmentation, freckles, and dark spots; ginkgo can nourish the skin and resist aging, dilate capillaries, promote blood circulation, make the skin rosy and refreshed; rose has anti-inflammatory, anti-oxidation, anti-virus, anti-tumor Angelica dahurica not only has antipyretic and anti-inflammatory effects, but also improves local blood circulation, eliminates the accumulation of pigment in the tissue, promotes the metabolism of skin cells, and achieves the effect of beauty; olive oil, which is rich in mono Unsaturated fatty acids, as well as vitamin A, vitamin B, vitamin D, vitamin E, vitamin K and antioxidants, etc., have excellent natural health care and beauty effects; honey is also rich in various nutrients, including vitamin A. Vitamin B1, vitamin B2, vitamin B6, vitamin C, vitamin D, vitamin K, fructose, glucose, protein, oxidase and trace elements can stimulate the blood circulation of the skin, improve the nutritional status of the skin, and improve the metabolism of the skin. Promote cell growth and delay aging; make the skin more elastic and tough, and the surface smoother and more moist.

In order to obtain the above-mentioned medicine, the white chrysanthemum flower, hibiscus leaf, mung bean, red hawthorn, peach kernel, ginkgo kernel, wintersweet flower, rose flower and fragrant Angelica dahurica were respectively cleaned, dried, crushed, passed through a 120-mesh sieve, and then Mix to get the medicinal powder and seal the package; when in use, the above medicinal powder is blended with olive oil and Sophora japonica nectar, and the amount of blending olive oil and Sophora japonica nectar is based on the paste made from the medicinal powder, wherein the volume ratio of olive oil and Sophora japonica nectar is 1:3.

The traditional Chinese medicine paste formula medicine of the present invention is easy to collect and purchase, the medicine price is also low, the preparation method is simple and convenient, and the use is convenient and safe. According to clinical observation, after 2 courses of treatment with the pharmaceutical formulation of the present invention, the total effective rate is 97.22%.

Detailed ways

The traditional Chinese medicine paste for treating pruritis according to the present invention is made of the following original medicines in parts by weight: 10-20 parts of white chrysanthemum, 10-20 parts of hibiscus leaf, 10-20 parts of mung bean, 2-6 parts of red hawthorn, 2 to 6 parts of peach kernels, 2 to 6 parts of ginkgo kernels, 2 to 6 parts of wintersweet flowers, 2 to 6 parts of rose flowers, and 2 to 6 parts of Angelica dahurica.

In order to obtain the above-mentioned medicine, the white chrysanthemum flower, hibiscus leaf, mung bean, red hawthorn, peach kernel, ginkgo kernel, wintersweet flower, rose flower and fragrant Angelica dahurica were respectively cleaned, dried, crushed, passed through a 120-mesh sieve, and then Mix to get the medicinal powder and seal the package; when in use, the above medicinal powder is blended with olive oil and Sophora japonica nectar, and the amount of blending olive oil and Sophora japonica nectar is based on the paste made from the medicinal powder, wherein the volume ratio of olive oil and Sophora japonica nectar is 1:3.

When in use, pour the above medicinal powder into a medicine bowl, add olive oil and Sophora japonica nectar, make a paste evenly with a medicine mixing board, spread it on the face, remove it after 30 minutes of external application, wash your face with warm water, once a day, 4 One week is a course of treatment; the amount of adding olive oil and nectar is based on the powder made into a paste, and the volume ratio of olive oil and nectar is 1:3.

Embodiment 1: the traditional Chinese medicine paste for the treatment of Pruriosis according to the present invention is made from the former medicine of following parts by weight: 10 parts of white chrysanthemum, 10 parts of lotus leaf, 10 parts of mung bean, 2 parts of red hawthorn, 2 parts of peach kernel, 2 parts of ginkgo kernels, 2 parts of wintersweet flowers, 2 parts of rose flowers, and 2 parts of fragrant angelica.

Embodiment 2: the traditional Chinese medicine paste for the treatment of Pruriosis according to the present invention is made from the former medicine of following parts by weight: 15 parts of white chrysanthemums, 15 parts of hibiscus leaves, 15 parts of mung beans, 4 parts of red hawthorn, 4 parts of peach kernels, 4 parts of ginkgo kernels, 4 parts of wintersweet flowers, 4 parts of rose flowers, and 4 parts of fragrant angelica.

Embodiment 3: the traditional Chinese medicine paste for the treatment of Pruriosis according to the present invention is made from the former medicine of following parts by weight: 15 parts of white chrysanthemums, 20 parts of lotus leaves, 20 parts of mung beans, 6 parts of red hawthorn, 6 parts of peach kernels, 6 parts of ginkgo kernels, 6 parts of wintersweet flowers, 6 parts of rose flowers, and 6 parts of fragrant angelica.

Clinical Observation Data

(1) The main function and therapeutic scope of the invented drug

1. Main functions: clear fire and detoxify, promote blood circulation and remove blood stasis, remove freckles and whiten skin

2. The scope of treatment: suitable for dark spots on the face.

(2) Clinical observation of the medicine of the present invention

1. Efficacy standard: cured means that the area of pigmented spots disappears > 90% with the naked eye, and the color basically disappears; markedly effective means that the area of pigmented spots fades with the naked eye > 60%, and the color becomes significantly lighter; effective means that the area of pigmented spots fades > 30% with the naked eye. The color becomes lighter; ineffective means that the area of the color spot disappears <30% according to the naked eye, and the color change is not obvious.

2. Treatment result: treatment group is treated with medicine of the present invention, and matched group is treated with hydroquinone cream. Results: The total effective rate of the present invention in treating Prurigo is 97.22%, and that of the control group is 77.77%. There is a significant difference between the two groups [p<0.05]. 

Table 1 Comparison of effective rates between the two groups

group no cure markedly effective efficient invalid Total effective rate (%) therapy group 36 twenty one 10 4 1 97.22 ^△ control group 36 8 11 9 8        77.77

Note: △ Compared with the control group, P <0.05, the difference between the two groups is significant.

It can be seen from Table 1 that the curative effect of the treatment group was significantly better than that of the control group (p<0.05).

Claims (1)

1. a Chinese medicine paste for the treatment of prurigo, characterized in that the Chinese medicine paste for the treatment of prurigo is made from the former medicine of the following parts by weight: 10 to 20 parts of hibiscus leaves, 10 to 20 parts of white chrysanthemums, 10-20 parts of mung bean, 2-6 parts of red hawthorn, 2-6 parts of peach kernel, 2-6 parts of ginkgo kernel, 2-6 parts of wintersweet flower, 2-6 parts of rose flower, 2-6 parts of Angelica dahurica; The hibiscus leaves, white chrysanthemums, mung beans, red hawthorn, peach kernels, ginkgo kernels, wintersweet flowers, rose flowers, and Angelica dahurica are washed separately, dried, crushed, passed through a 120-mesh sieve, and then mixed to obtain a medicinal powder, which can be sealed and packaged; use At the same time, the above medicinal powder is mixed with olive oil and Sophora japonica nectar, and the amount of blending olive oil and Sophora japonica nectar is based on the paste made from the medicinal powder, wherein the volume ratio of olive oil and Sophora japonica nectar is 1:3.