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CL2008002384A1 - Compounds derived from quinolinyloxypiperidine and pyrrolidine, pharmaceutical composition, pharmaceutical combination, useful for the treatment of inflammatory and / or allergic diseases of the respiratory tract. - Google Patents

Compounds derived from quinolinyloxypiperidine and pyrrolidine, pharmaceutical composition, pharmaceutical combination, useful for the treatment of inflammatory and / or allergic diseases of the respiratory tract.

Info

Publication number
CL2008002384A1
CL2008002384A1 CL2008002384A CL2008002384A CL2008002384A1 CL 2008002384 A1 CL2008002384 A1 CL 2008002384A1 CL 2008002384 A CL2008002384 A CL 2008002384A CL 2008002384 A CL2008002384 A CL 2008002384A CL 2008002384 A1 CL2008002384 A1 CL 2008002384A1
Authority
CL
Chile
Prior art keywords
quinolinyloxypiperidine
pyrrolidine
inflammatory
useful
treatment
Prior art date
Application number
CL2008002384A
Other languages
Spanish (es)
Inventor
Panayiotis Alexandrou Procopiou
Ashley Paul Hancock
Paul Martin Gore
Simon Teanby Hodgson
Sadie Vile
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CL2008002384A1 publication Critical patent/CL2008002384A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compuestos derivados de quinoliniloxipiperidina y pirrolidina, composición farmacéutica, combinación farmacéutica, útil para el tratamiento de enfermedades inflamatorias y/o alérgicas del tracto respiratorio.Compounds derived from quinolinyloxypiperidine and pyrrolidine, pharmaceutical composition, pharmaceutical combination, useful for the treatment of inflammatory and / or allergic diseases of the respiratory tract.

CL2008002384A 2007-08-15 2008-08-13 Compounds derived from quinolinyloxypiperidine and pyrrolidine, pharmaceutical composition, pharmaceutical combination, useful for the treatment of inflammatory and / or allergic diseases of the respiratory tract. CL2008002384A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95594107P 2007-08-15 2007-08-15
US8258508P 2008-07-22 2008-07-22

Publications (1)

Publication Number Publication Date
CL2008002384A1 true CL2008002384A1 (en) 2009-07-17

Family

ID=40351220

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008002384A CL2008002384A1 (en) 2007-08-15 2008-08-13 Compounds derived from quinolinyloxypiperidine and pyrrolidine, pharmaceutical composition, pharmaceutical combination, useful for the treatment of inflammatory and / or allergic diseases of the respiratory tract.

Country Status (8)

Country Link
US (2) US7884114B2 (en)
EP (1) EP2185542A2 (en)
JP (1) JP2010535845A (en)
AR (1) AR067927A1 (en)
CL (1) CL2008002384A1 (en)
PE (1) PE20090595A1 (en)
TW (1) TW200922581A (en)
WO (1) WO2009021965A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009050204A1 (en) * 2007-10-16 2009-04-23 Glaxo Group Limited Quinoline derivatives used to treat inflammatory and allergic diseases
WO2012045729A1 (en) 2010-10-05 2012-04-12 Glaxo Group Limited Imidazo [1, 2 -a] pyridine and pyrazolo [1, 5 -a] pyridine derivatives as trpv1 antagonists
WO2012072512A1 (en) 2010-11-29 2012-06-07 Glaxo Group Limited N-cyclobutyl-imidazopyridine or -pyrazolopyridine carboxamides as trpv1 antagonists
JP2014510768A (en) 2011-04-11 2014-05-01 グラクソ グループ リミテッド N-cyclobutylimidazopyridine methylamine as a TRPV1 antagonist
WO2014022752A1 (en) 2012-08-03 2014-02-06 Amgen Inc. Macrocycles as pim inhibitors
EP2963027B1 (en) 2013-02-28 2018-12-26 TiumBio Co., Ltd. Tricyclic compound and use thereof
WO2015028976A2 (en) * 2013-08-30 2015-03-05 Mahesh Kandula Compounds and methods for the treatment of inflammatory diseases
US10377775B2 (en) 2014-12-04 2019-08-13 Shin-Etsu Chemical Co., Ltd. Method for producing polyalkylene glycol derivative having amino group at end
US9708350B2 (en) 2014-12-04 2017-07-18 Shin-Etsu Chemical Co., Ltd. Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator
JP6460937B2 (en) * 2014-12-04 2019-01-30 信越化学工業株式会社 Method for producing polyalkylene glycol derivative having amino group at terminal
CA3200753A1 (en) * 2020-12-11 2022-06-16 Mahesh Kandula A composition comprising fexofenadine

Family Cites Families (21)

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DE3632329A1 (en) * 1986-09-24 1988-03-31 Bayer Ag SUBSTITUTED PHENYLSULPHONAMID
FR2737892B1 (en) * 1995-08-17 1997-10-24 Fournier Ind & Sante NOVEL BENZENESULFONAMIDE COMPOUNDS, PREPARATION METHOD AND THERAPEUTIC USE
AU2001234690A1 (en) 2000-02-01 2001-08-14 Cor Therapeutics, Inc. 2-(1h)-quinolone and 2-(1h)-quinoxalone inhibitors of factor xa
ATE341545T1 (en) 2001-07-16 2006-10-15 Astrazeneca Ab QUINOLINE DERIVATIVES AND THEIR USE AS TYROSINE KINASE INHIBITORS
AU2002365664A1 (en) 2001-12-05 2003-06-17 Astrazeneca Ab Quinoline derivatives as antitumour agents
AU2002365665A1 (en) 2001-12-05 2003-06-17 Astrazeneca Ab Pharmaceutical compositions comprising benzofuranyl substituted 3-cyanoquinoline derivatives and their use for the treatment of solid tumours
WO2003047584A1 (en) 2001-12-05 2003-06-12 Astrazeneca Ab Quinoline derivatives
WO2003048159A1 (en) 2001-12-05 2003-06-12 Astrazeneca Ab Quinoline derivatives
WO2003047585A1 (en) 2001-12-05 2003-06-12 Astrazeneca Ab Pharmaceutical compositions comprising benzofuranyl substituted 3-cyanoquinoline derivatives and their use for the treatment of solid tumours
WO2003105850A1 (en) 2002-06-18 2003-12-24 Abbott Laboratories 2-aminoquinolines as melanin concentrating hormone receptor antagonists
GB0215823D0 (en) 2002-07-09 2002-08-14 Astrazeneca Ab Quinazoline derivatives
US20040033959A1 (en) 2002-07-19 2004-02-19 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical compositions for hepatitis C viral protease inhibitors
TWI347946B (en) * 2002-10-11 2011-09-01 Otsuka Pharma Co Ltd 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound
EP1608639A2 (en) 2003-02-28 2005-12-28 Bayer Pharmaceuticals Corporation Novel bicyclic urea derivatives useful in the treatment of cancer and other disorders
DE10316081A1 (en) * 2003-04-08 2004-10-21 Morphochem AG Aktiengesellschaft für kombinatorische Chemie New compounds with antibacterial activity
SI2210607T1 (en) 2003-09-26 2011-11-30 Exelixis Inc N-?á3-fluoro-4-(?í6-(methyloxy)-7-?á(3-morpholin-4-ylpropyl)oxy?åquinolin-4-yl?çoxy)phenyl?å-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide for the treatment of cancer
FR2865205B1 (en) * 2004-01-16 2006-02-24 Sanofi Synthelabo ARYLOXYALKYLCARBAMATE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF
GB0407025D0 (en) 2004-03-29 2004-04-28 Glaxo Group Ltd Novel compounds
JP5314244B2 (en) 2004-10-27 2013-10-16 富山化学工業株式会社 Novel nitrogen-containing heterocyclic compounds and salts thereof
CA2603748A1 (en) 2005-04-06 2006-10-12 Exelixis, Inc. C-met modulators and methods of use
WO2006110516A1 (en) 2005-04-11 2006-10-19 Abbott Laboratories Acylhydrazide p2x7 antagonists and uses thereof

Also Published As

Publication number Publication date
WO2009021965A2 (en) 2009-02-19
TW200922581A (en) 2009-06-01
AR067927A1 (en) 2009-10-28
EP2185542A2 (en) 2010-05-19
PE20090595A1 (en) 2009-06-06
JP2010535845A (en) 2010-11-25
US7884114B2 (en) 2011-02-08
US20110281909A1 (en) 2011-11-17
WO2009021965A3 (en) 2009-04-16
US20090270355A1 (en) 2009-10-29

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