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BR112013030381A2 - reagentes e métodos para tratar doença dental - Google Patents

reagentes e métodos para tratar doença dental

Info

Publication number
BR112013030381A2
BR112013030381A2 BR112013030381A BR112013030381A BR112013030381A2 BR 112013030381 A2 BR112013030381 A2 BR 112013030381A2 BR 112013030381 A BR112013030381 A BR 112013030381A BR 112013030381 A BR112013030381 A BR 112013030381A BR 112013030381 A2 BR112013030381 A2 BR 112013030381A2
Authority
BR
Brazil
Prior art keywords
reagents
methods
treating dental
dental disease
disease
Prior art date
Application number
BR112013030381A
Other languages
English (en)
Other versions
BR112013030381B1 (pt
Inventor
Tamerler-Behar Candan
Zhang Hai
Fong Hanson
Somerman Martha
Sarikaya Mehmet
Gungormus Mustafa
Original Assignee
Univ Washington Through Its Center For Commercialization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington Through Its Center For Commercialization filed Critical Univ Washington Through Its Center For Commercialization
Publication of BR112013030381A2 publication Critical patent/BR112013030381A2/pt
Publication of BR112013030381B1 publication Critical patent/BR112013030381B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Birds (AREA)
  • General Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
BR112013030381-6A 2011-05-27 2012-05-25 Produto de cuidado oral BR112013030381B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161490757P 2011-05-27 2011-05-27
US61/490,757 2011-05-27
US201161509986P 2011-07-20 2011-07-20
US61/509,986 2011-07-20
PCT/US2012/039650 WO2012166626A1 (en) 2011-05-27 2012-05-25 Reagents and methods for treating dental disease

Publications (2)

Publication Number Publication Date
BR112013030381A2 true BR112013030381A2 (pt) 2017-08-08
BR112013030381B1 BR112013030381B1 (pt) 2021-10-26

Family

ID=46208844

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013030381-6A BR112013030381B1 (pt) 2011-05-27 2012-05-25 Produto de cuidado oral

Country Status (5)

Country Link
US (2) US9290555B2 (pt)
JP (2) JP2014517693A (pt)
KR (1) KR20140056187A (pt)
BR (1) BR112013030381B1 (pt)
WO (1) WO2012166626A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012166626A1 (en) 2011-05-27 2012-12-06 University Of Washington Through Its Center For Commercialization Reagents and methods for treating dental disease
JP6134146B2 (ja) * 2012-01-30 2017-05-24 国立大学法人広島大学 ヒトアメロゲニン部分ペプチド
US20160324728A1 (en) * 2014-01-17 2016-11-10 Straumann Holding Ag Process for Producing EMD of Increased Stability
CN107427560B (zh) * 2015-01-13 2021-06-15 华盛顿大学商业中心 用于增白牙齿的试剂和方法
US9962465B2 (en) * 2015-07-07 2018-05-08 University Of Southern California Amelogenin-chitosan hydrogel for dentin hypersensitivity
JP7019567B2 (ja) 2015-10-26 2022-02-15 ビーエーエスエフ ソシエタス・ヨーロピア 不凍タンパク質を含む口腔ケア製品及び方法
RU2745996C2 (ru) * 2015-10-26 2021-04-05 Басф Се Продукты и способы для ухода за полостью рта, содержащие гидроксиапатит-связывающие белки
BR112018008214B1 (pt) * 2015-10-26 2021-12-14 Basf Se Métodos para reparar ou inibir a erosão dentária e para fabricar um produto de cuidado oral, dentifrício, composição, e, proteína semelhante à hidrofobina
WO2017123986A1 (en) * 2016-01-13 2017-07-20 University Of Washington Reagents and methods for mineralization of tooth enamel
JP6962707B2 (ja) * 2017-05-19 2021-11-05 プリマハム株式会社 洗浄剤組成物
BR112021003356A2 (pt) * 2018-08-30 2021-05-25 University Of Washington composições e métodos para assistência odontológica
US20230201315A1 (en) 2020-01-03 2023-06-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Tnap locally administered for promoting periodontal health
CN116848129A (zh) * 2021-02-16 2023-10-03 香港大学 抗菌和矿化组合物及其使用方法
CN113321710B (zh) * 2021-05-27 2022-07-05 吉林大学 一种具有促进釉质结构性矿化再生功能的多肽
WO2024081656A1 (en) * 2022-10-14 2024-04-18 Ohio State Innovation Foundation Bone sialoprotein compositions and methods of using thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2241489C2 (ru) 1998-02-27 2004-12-10 Биора Биоэкс Аб Композиции матриксных протеинов для залечивания ран
WO2000006734A1 (en) 1998-07-29 2000-02-10 Northwestern University Chondrogenic and osteogenic inducing molecule
US6677306B1 (en) 1998-07-29 2004-01-13 Northwestern University Chondrogenic and osteogenic inducing molecule
ATE401350T1 (de) 2000-08-16 2008-08-15 Acologix Inc Dentalzubereitungen enthaltend peptide, die das knochenwachstum fördern
BR0212527A (pt) * 2001-09-14 2004-10-19 Biora Bioex Ab Composições de proteìna de matriz esmaltada para modulação de resposta imune
US7132015B2 (en) * 2002-02-20 2006-11-07 University Of Southern California Materials for dental and biomedical application
CN1982453A (zh) * 2005-12-12 2007-06-20 杨淑伟 人类新基因及其编码多肽的用途
EP2520935A3 (en) 2006-08-09 2013-02-13 Homestead Clinical Corporation Organ-specific proteins and methods of their use
JP2011525913A (ja) * 2008-06-27 2011-09-29 ストラウマン ホールディング アーゲー エナメル基質誘導体の画分ｃ
US20100070200A1 (en) 2008-09-17 2010-03-18 Mehmet Sarikaya Method and system for designing polypeptides and polypeptide-like polymers with specific chemical and physical characteristics
WO2011073447A1 (en) 2009-12-18 2011-06-23 Straumann Holding Ag Emd c-depleted
GB0922438D0 (en) 2009-12-22 2010-02-03 Ucl Business Plc Agents having tissue generative activity
WO2012166626A1 (en) 2011-05-27 2012-12-06 University Of Washington Through Its Center For Commercialization Reagents and methods for treating dental disease
JP6134146B2 (ja) * 2012-01-30 2017-05-24 国立大学法人広島大学 ヒトアメロゲニン部分ペプチド
US20140186273A1 (en) * 2012-12-27 2014-07-03 University Of Southern California Chitosan -Amelogenin Hydrogel for In Situ Enamel Growth
CN107427560B (zh) 2015-01-13 2021-06-15 华盛顿大学商业中心 用于增白牙齿的试剂和方法

Also Published As

Publication number Publication date
JP2017012188A (ja) 2017-01-19
US20160152672A1 (en) 2016-06-02
BR112013030381B1 (pt) 2021-10-26
KR20140056187A (ko) 2014-05-09
JP2014517693A (ja) 2014-07-24
US9290555B2 (en) 2016-03-22
US9809633B2 (en) 2017-11-07
WO2012166626A1 (en) 2012-12-06
US20150065435A1 (en) 2015-03-05
WO2012166626A8 (en) 2014-01-03

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/05/2012, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 13A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2828 DE 18-03-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.