diff --git a/lib/matplotlib/backends/backend_wx.py b/lib/matplotlib/backends/backend_wx.py
index da78f69d9e8e..bc80d0f0b564 100644
--- a/lib/matplotlib/backends/backend_wx.py
+++ b/lib/matplotlib/backends/backend_wx.py
@@ -515,6 +515,12 @@ def __init__(self, parent, id, figure=None):
         self.Bind(wx.EVT_RIGHT_DOWN, self._onMouseButton)
         self.Bind(wx.EVT_RIGHT_DCLICK, self._onMouseButton)
         self.Bind(wx.EVT_RIGHT_UP, self._onMouseButton)
+        self.Bind(wx.EVT_MOUSE_AUX1_DOWN, self._onMouseButton)
+        self.Bind(wx.EVT_MOUSE_AUX1_UP, self._onMouseButton)
+        self.Bind(wx.EVT_MOUSE_AUX2_DOWN, self._onMouseButton)
+        self.Bind(wx.EVT_MOUSE_AUX2_UP, self._onMouseButton)
+        self.Bind(wx.EVT_MOUSE_AUX1_DCLICK, self._onMouseButton)
+        self.Bind(wx.EVT_MOUSE_AUX2_DCLICK, self._onMouseButton)
         self.Bind(wx.EVT_MOUSEWHEEL, self._onMouseWheel)
         self.Bind(wx.EVT_MOTION, self._onMotion)
         self.Bind(wx.EVT_LEAVE_WINDOW, self._onLeave)
@@ -766,6 +772,8 @@ def _onMouseButton(self, event):
             wx.MOUSE_BTN_LEFT: MouseButton.LEFT,
             wx.MOUSE_BTN_MIDDLE: MouseButton.MIDDLE,
             wx.MOUSE_BTN_RIGHT: MouseButton.RIGHT,
+            wx.MOUSE_BTN_AUX1: MouseButton.BACK,
+            wx.MOUSE_BTN_AUX2: MouseButton.FORWARD,
         }
         button = event.GetButton()
         button = button_map.get(button, button)