diff --git a/.release-please-manifest.json b/.release-please-manifest.json
index eeb4bcda..5be20145 100644
--- a/.release-please-manifest.json
+++ b/.release-please-manifest.json
@@ -1,3 +1,3 @@
 {
-    ".": "2.20.2"
+    ".": "2.21.0"
 }
\ No newline at end of file
diff --git a/CHANGELOG.md b/CHANGELOG.md
index 549b44f4..0ed89fd5 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -4,6 +4,21 @@
 
 [1]: https://pypi.org/project/google-cloud-datastore/#history
 
+## [2.21.0](https://github.com/googleapis/python-datastore/compare/v2.20.2...v2.21.0) (2025-04-10)
+
+
+### Features
+
+* Add REST Interceptors which support reading metadata ([7be9c4c](https://github.com/googleapis/python-datastore/commit/7be9c4c594af2c2414e394b8bfe62574b58ef337))
+* Add support for opt-in debug logging ([7be9c4c](https://github.com/googleapis/python-datastore/commit/7be9c4c594af2c2414e394b8bfe62574b58ef337))
+
+
+### Bug Fixes
+
+* Allow protobuf 6.x ([#598](https://github.com/googleapis/python-datastore/issues/598)) ([7c1171b](https://github.com/googleapis/python-datastore/commit/7c1171bf657f7cf4d1404e19611f6c874a8998ca))
+* Backwards-compatibility for previous meaning format ([#603](https://github.com/googleapis/python-datastore/issues/603)) ([ed92e8e](https://github.com/googleapis/python-datastore/commit/ed92e8e54a9e0f44302efee89a30a322d0a73636))
+* Fix typing issue with gRPC metadata when key ends in -bin ([7be9c4c](https://github.com/googleapis/python-datastore/commit/7be9c4c594af2c2414e394b8bfe62574b58ef337))
+
 ## [2.20.2](https://github.com/googleapis/python-datastore/compare/v2.20.1...v2.20.2) (2024-12-12)
 
 
diff --git a/google/cloud/datastore/gapic_version.py b/google/cloud/datastore/gapic_version.py
index 6975b43d..81570778 100644
--- a/google/cloud/datastore/gapic_version.py
+++ b/google/cloud/datastore/gapic_version.py
@@ -12,4 +12,4 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
-__version__ = "2.20.2"  # {x-release-please-version}
+__version__ = "2.21.0"  # {x-release-please-version}
diff --git a/google/cloud/datastore/version.py b/google/cloud/datastore/version.py
index e37230a6..563b0e16 100644
--- a/google/cloud/datastore/version.py
+++ b/google/cloud/datastore/version.py
@@ -12,4 +12,4 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
-__version__ = "2.20.2"
+__version__ = "2.21.0"
diff --git a/google/cloud/datastore_admin/gapic_version.py b/google/cloud/datastore_admin/gapic_version.py
index 4c1787c5..e546bae0 100644
--- a/google/cloud/datastore_admin/gapic_version.py
+++ b/google/cloud/datastore_admin/gapic_version.py
@@ -13,4 +13,4 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 #
-__version__ = "2.20.2"  # {x-release-please-version}
+__version__ = "2.21.0"  # {x-release-please-version}
diff --git a/google/cloud/datastore_admin_v1/gapic_version.py b/google/cloud/datastore_admin_v1/gapic_version.py
index efd18799..6e29ec5f 100644
--- a/google/cloud/datastore_admin_v1/gapic_version.py
+++ b/google/cloud/datastore_admin_v1/gapic_version.py
@@ -12,4 +12,4 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
-__version__ = "2.20.2"  # {x-release-please-version}
+__version__ = "2.21.0"  # {x-release-please-version}
diff --git a/google/cloud/datastore_v1/gapic_version.py b/google/cloud/datastore_v1/gapic_version.py
index efd18799..6e29ec5f 100644
--- a/google/cloud/datastore_v1/gapic_version.py
+++ b/google/cloud/datastore_v1/gapic_version.py
@@ -12,4 +12,4 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
-__version__ = "2.20.2"  # {x-release-please-version}
+__version__ = "2.21.0"  # {x-release-please-version}