Bronwen Martin
The aim of the Metabolism Unit is to use an integrative systems biology approach to understand the multitude of factors that control metabolic function and energy homeostasis. Metabolism and aging are highly complex biological traits that involve entire networks of changes at both a molecular and systemic level, and require a broad systems approach to understanding how these networks change with age or are disrupted during disease. Dr Martin’s group focuses on the development of novel therapeutic strategies that enhance metabolic function during the aging process and aims to uncover effective treatment avenues for complex aging-related disorders that have underlying endocrine pathophysiologies. Additionally, the Metabolism Unit is investigating how cognitive ability or susceptibility to neurodegenerative disorders is affected by general systemic metabolic function, and how cognitive decline during aging could potentially be reduced by enhancing general metabolic health. The Metabolism Unit uses genetic, proteomic, bioinformatic, metabolomic, NMR, in vitro and animal behavioral approaches to investigate alterations in metabolic function and energy homeostasis during aging, and to screen potential drug candidates and targets that can maintain or enhance metabolic control.
Address: National Institute on Aging – National Institutes of Health
251 Bayview Blvd., Suite 100
Baltimore, MD 21224, USA
Phone: (410) 558-8652
Email: martinbro@mail.nih.gov
Address: National Institute on Aging – National Institutes of Health
251 Bayview Blvd., Suite 100
Baltimore, MD 21224, USA
Phone: (410) 558-8652
Email: martinbro@mail.nih.gov
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