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URL of this page: https://medlineplus.gov/lab-tests/nasal-swab/

Nasal Swab

What is a nasal swab?

A nasal swab is a test that checks for viruses and bacteria that cause respiratory infections.

There are many types of respiratory infections. A nasal swab test can help your health care provider diagnose the type of infection you have and determine which treatment would be best for you. The test may be done by taking a sample of cells from inside your nostrils or from the nasopharynx, the uppermost part of your nose and throat.

Other names: anterior nares test, nasal mid-turbinate swab, NMT swab nasopharyngeal culture, nasopharyngeal (NP) swab

What is it used for?

A nasal swab is used to diagnose certain infections of the respiratory system. These can include:

  • The flu.
  • COVID-19.
  • Respiratory syncytial virus (RSV), a common and usually mild respiratory infection. But it can cause serious lung infections in infants and older adults.
  • Whooping cough, a respiratory infection that can cause coughing fits. Coughing can become violent and rapid.
  • Meningitis, a disease caused by inflammation of the membranes that surround the brain and spinal cord.
  • MRSA (methicillin-resistant Staphylococcus aureus), a serious type of bacterial infection that can be very difficult to treat.

Why do I need a nasal swab?

You may need this test if you have symptoms of a respiratory infection. They can include:

What happens during a nasal swab?

A nasal swab may be taken from:

  • The front part of your nostrils (anterior nares).
    • You or your provider might collect the sample.
    • It's less uncomfortable than other types of swab tests.
  • The back of your nostrils, in a procedure known as nasal mid-turbinate (NMT) swab.
    • You or your provider might collect the sample.
  • Your nasopharynx (the uppermost part of your nose and throat), which is deeper into your respiratory system.
    • Your provider must collect the sample.
    • It's less comfortable than other types of nasal swab tests.
    • It's more effective for detecting viruses or bacteria in the upper respiratory tract.

During an anterior nares test, you will start by tilting your head back. Then you or your provider will:

  • Gently insert a swab inside your nostril.
  • Rotate the swab in four or five sweeping circles for 10-15 seconds.
  • Remove the swab and insert it into your second nostril.
  • Swab the second nostril using the same technique.
  • Remove the swab.

If you only swab one nostril, don't rotate the swab in your nostril, or only keep the swab in one area, you may not get a good sample.

If you are doing the test yourself, your provider will let you know how to prepare and package your sample. This often involves placing your swab in a sterile tube, closing it, and sealing it in a special bag. You would then give that bag to your provider or follow the instructions on how to return your sample for testing.

During an NMT swab, you will start by tilting your head back. Then you or your provider will:

  • Gently insert a swab onto the bottom of your nostril, pushing it until you feel it stopping.
  • Rotate the swab for 10 to 15 seconds.
  • Remove the swab and insert it into your second nostril.
  • Swab the second nostril using the same technique.
  • Remove the swab.

If you only swab one nostril, don't rotate the swab in your nostril, or only keep the swab in one area, you may not get a good sample.

If you are doing the test yourself, the provider will let you know how to prepare and package your sample. This often involves placing your swab in a sterile tube, closing it, and sealing it in a special bag. You would then give that bag to your provider or follow the instructions on how to return your samplefor testing.

During a nasopharyngeal (NP) swab:

  • You will tilt your head back.
  • Your provider will insert a long swab into your nostril until it reaches your nasopharynx (the upper part of your throat).
  • Your provider will rotate the swab for 10 to 15 seconds and remove it.

If your provider gets enough of a sample from one of your nostrils, they may only need to do one. But they may need to get a sample from your other nostril as well if they had trouble getting the sample from the first side.

Will I need to do anything to prepare for the test?

You don't need any special preparations for a nasal swab.

Are there any risks to the test?

The test may tickle your throat or cause you to cough. A nasopharyngeal swab may be uncomfortable and cause coughing or gagging. All these effects are temporary.

What do the results mean?

A negative result means no harmful viruses or bacteria were found in your sample.

A positive result means a specific type of harmful virus or bacteria was found in your sample. If you are diagnosed with an infection, follow your provider's recommendations for treating your illness. This may include medicines and steps to prevent spreading the infection.

To understand the results of a nasal swab test, your provider may consider your symptoms, medical history, and the results of other tests.

Learn more about laboratory tests, reference ranges, and understanding results.

References

  1. American Lung Association [Internet]. Chicago: American Lung Association; c2024. COVID-19 Symptoms; [reviewed 2024 Feb 2; cited 2024 Mar 27]; [about 3 screens]. Available from: https://www.lung.org/lung-health-diseases/lung-disease-lookup/COVID-19/symptoms-diagnosis
  2. Centers for Disease Control and Prevention [Internet]. Atlanta: U.S. Department of Health and Human Services; COVID-19: Interim Guidelines for Collecting and Handling of Clinical Specimens for COVID-19 Testing; [updated 2024 Jun 4; cited 2024 Jun 25]; [about 7 screens]. Available from: https://www.cdc.gov/covid/hcp/clinical-care/clinical-specimen-guidelines.html
  3. Centers for Disease Control and Prevention [Internet]. Atlanta: U.S. Department of Health and Human Services; COVID-19: Symptoms of COVID-19; [updated 2024 Jun 25; cited 2024 Jun 25]; [about 3 screens]. Available from: https://www.cdc.gov/covid/signs-symptoms/
  4. Centers for Disease Control and Prevention [Internet]. Atlanta: U.S. Department of Health and Human Services; COVID-19: Testing for COVID-19; [updated 2024 Jun 25; cited 2024 Aug 2]; [about 5 screens]. Available from: https://www.cdc.gov/covid/testing/
  5. Cleveland Clinic: Health Library: Diagnostics & Testing [Internet]. Cleveland (OH): Cleveland Clinic; c2024. Meningitis; [reviewed 2022 Aug 22; cited 2024 Mar 28]; [about 15 screens]. Available from: https://my.clevelandclinic.org/health/diseases/14600-meningitis
  6. Cleveland Clinic: Health Library: Diagnostics & Testing [Internet]. Cleveland (OH): Cleveland Clinic; c2024. Methicillin-Resistant Staphylococcus Aureus (MRSA); [reviewed 2021 Jan 19; cited 2024 Mar 28]; [about 7 screens]. Available from: https://my.clevelandclinic.org/health/diseases/11633-methicillin-resistant-staphylococcus-aureus-mrsa
  7. Cleveland Clinic: Health Library: Diagnostics & Testing [Internet]. Cleveland (OH): Cleveland Clinic; c2024. Nasopharyngeal Swab; [reviewed 2022 May 02; cited 2024 Mar 28]; [about 6 screens]. Available from: https://my.clevelandclinic.org/health/diagnostics/22878-nasopharyngeal-swab
  8. Hinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Tests. 2nd Ed, Kindle. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Nasopharyngeal Culture; p. 386.
  9. Marty FM, Chen K, Verrill KA. How to Obtain a Nasopharyngeal Swab Specimen. N Engl J Med [Internet]. 2020 May 29 [cited 2024 Mar 27]; 382(10):1056. Available from: https://pubmed.ncbi.nlm.nih.gov/32469478/?from_term=How+to+Obtain+a+Nasopharyngeal+Swab+Specimen.+&from_sort=date&from_pos=1
  10. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998-2024. MRSA Infection; [cited 2024 Mar 28]; [about 3 screens]. Available from: https://www.mayoclinic.org/diseases-conditions/mrsa/diagnosis-treatment/drc-20375340
  11. Rush [Internet]. Chicago: Rush University Medical Center, Rush Copley Medical Center or Rush Oak Park Hospital; c2020. Swab Differences for POC and Standard COVID Testing; [cited 2024 Mar 27]; [about 1 screens]. Available from: https://www.rush.edu/sites/default/files/2020-09/coronavirus-swab-differences.pdf
  12. Testing.com [Internet]. Seattle (WA): OneCare Media; c2024. Coronavirus (COVID-19) Testing; [modified 2021 Nov 9; cited 2024 Mar 27]; [about 10 screens]. Available from: https://www.testing.com/coronavirus-covid-19-testing/
  13. Testing.com [Internet]. Seattle (WA): OneCare Media; c2024. Proper Self-collection of Nasal Swabs Critical for Accurate COVID-19 Testing; [modified 2020 Nov 12; cited 2024 Mar 28]; [about 5 screens]. Available from: https://www.testing.com/news/proper-self-collection-nasal-swabs-critical-accurate-covid-19-testing/
  14. Testing.com [Internet]. Seattle (WA): OneCare Media; c2024. Respiratory Syncytial Virus (RSV) Testing; [modified 2020 Oct 2; cited 2024 Mar 27]; [about 9 screens]. Available from: https://www.testing.com/tests/respiratory-syncytial-virus-rsv-testing/
  15. Uršič T, Kogoj R, Šikonja J, Jevšnik Virant M, Petrovec M. A simplified nasopharyngeal swab collection procedure for minimizing patient discomfort while retaining sample quality. Front Public Health. 2023 Mar 23;11:1066934. [cited 2024 Mar 289]; [about 9 screens]. doi: 10.3389/fpubh.2023.1066934. PMID: 37033037; PMCID: PMC10076767.
  16. Vermont Department of Public Health [Internet]. Burlington (VT): Procedure for Collecting an Anterior Nares Swab; 2020 Jun 22 [cited 2024 Mar 27]; [about 5 screens]. Available from: https://www.healthvermont.gov/sites/default/files/DEPRIP.EMSNasalNares%20Procedure%20for%20Anterior%20Nares%20Nasal%20Swab.pdf
  17. Very Well Health [Internet]. New York: About, Inc.; c2024. What Is an Upper Respiratory Infection; [updated 2023 Sep 11; cited 2024 Mar 27]; [about 3 screens]. Available from: https://www.verywellhealth.com/upper-respiratory-infection-overview-4582263
  18. Washington State Department of Health [Internet].Swab Instructions Mid-turbinate self-swab nasal specimen collection; [cited 2024 Mar 27][about 2 screens]. Available from: https://www.doh.wa.gov/Portals/1/Documents/1600/coronavirus/Self-SwabMid-turbinateCollectionInstructions.pdf

The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.